Edifenphos (BioDeep_00001873644)

Main id: BioDeep_00000009899

 

Industrial Pollutants


代谢物信息卡片


O-Ethyl-S,S-diphenyl dithiophosphate

化学式: C14H15O2PS2 (310.0251)
中文名称: 甲醇中敌瘟磷溶液, 烯啶虫胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCOP(=O)(SC1=CC=CC=C1)SC2=CC=CC=C2
InChI: InChI=1S/C14H15O2PS2/c1-2-16-17(15,18-13-9-5-3-6-10-13)19-14-11-7-4-8-12-14/h3-12H,2H2,1H3

描述信息

同义名列表

6 个代谢物同义名

O-Ethyl-S,S-diphenyl dithiophosphate; Edifenphos; EDDP; EFP; Edifenphos; Edifenphos



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 ABCB1, ALB, ARHGAP45, CASP3, CASP9, CNP, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP3A4, HELB
Peripheral membrane protein 3 ACHE, CYP2B6, OSBP2
Endoplasmic reticulum membrane 6 CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP3A4
Nucleus 6 ACHE, ALB, APCS, CASP3, CASP9, HELB
cytosol 7 ALB, AP1AR, ARHGAP45, CASP3, CASP9, HELB, OSBP2
nuclear body 1 HELB
centrosome 1 ALB
nucleoplasm 3 CASP3, CD2, HELB
Cell membrane 3 ABCB1, ACHE, CD2
Lipid-anchor 1 CNP
ruffle membrane 1 ARHGAP45
Multi-pass membrane protein 1 ABCB1
Synapse 2 ACHE, CNP
cell surface 3 ABCB1, ACHE, CD2
glutamatergic synapse 2 CASP3, LRRC4C
Golgi apparatus 4 ACHE, ALB, AP1AR, CD2
mitochondrial inner membrane 1 CNP
neuromuscular junction 1 ACHE
neuronal cell body 1 CASP3
acrosomal vesicle 1 OSBP2
endosome 1 AP1AR
plasma membrane 10 ABCB1, ACHE, ARHGAP45, BCHE, CD2, CYP2C19, CYP2C8, CYP2C9, LRRC4C, OSBP2
Membrane 8 ABCB1, ACHE, ARHGAP45, CNP, CYP2D6, CYP3A4, LRRC4C, OSBP2
apical plasma membrane 1 ABCB1
extracellular exosome 4 ABCB1, ALB, APCS, CNP
endoplasmic reticulum 2 ALB, CYP2D6
extracellular space 6 ACHE, ALB, APCS, BCHE, CNP, LRRC4C
perinuclear region of cytoplasm 2 ACHE, CNP
Schaffer collateral - CA1 synapse 1 LRRC4C
mitochondrion 3 CASP9, CYP2D6, HELB
protein-containing complex 3 ALB, CASP9, CD2
intracellular membrane-bounded organelle 6 CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP3A4
Microsome membrane 4 CYP2B6, CYP2C9, CYP2D6, CYP3A4
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 CD2, LRRC4C
Secreted 4 ACHE, ALB, APCS, BCHE
extracellular region 6 ACHE, ALB, APCS, ARHGAP45, BCHE, CD2
cytoplasmic side of plasma membrane 1 CD2
Single-pass membrane protein 1 CYP2D6
mitochondrial outer membrane 1 CNP
Extracellular side 1 ACHE
anchoring junction 1 ALB
external side of plasma membrane 1 CD2
Early endosome 1 AP1AR
cell-cell junction 1 CD2
Apical cell membrane 1 ABCB1
Cell projection, ruffle membrane 1 ARHGAP45
microtubule 1 CNP
basement membrane 1 ACHE
collagen-containing extracellular matrix 1 APCS
Postsynaptic cell membrane 1 LRRC4C
Late endosome 1 AP1AR
ciliary basal body 1 ALB
Chromosome 1 HELB
centriole 1 ALB
Cytoplasmic vesicle, secretory vesicle, acrosome 1 OSBP2
spindle pole 1 ALB
blood microparticle 3 ALB, APCS, BCHE
Lipid-anchor, GPI-anchor 1 ACHE
site of double-strand break 1 HELB
microvillus 1 CNP
Melanosome 1 CNP
side of membrane 1 ACHE
pseudopodium 1 CNP
secretory granule lumen 1 ARHGAP45
endoplasmic reticulum lumen 2 ALB, BCHE
platelet alpha granule lumen 1 ALB
transport vesicle 1 AP1AR
azurophil granule lumen 1 ARHGAP45
postsynaptic density membrane 1 LRRC4C
perinuclear endoplasmic reticulum 1 OSBP2
nuclear envelope lumen 1 BCHE
apoptosome 1 CASP9
synaptic cleft 1 ACHE
external side of apical plasma membrane 1 ABCB1
apical dendrite 1 OSBP2
death-inducing signaling complex 1 CASP3
myelin sheath abaxonal region 1 CNP
myelin sheath adaxonal region 1 CNP
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB
caspase complex 1 CASP9


文献列表

  • Ajaz Ahmad, Pooja Kumari, Masood Ahmad. Apigenin attenuates edifenphos-induced toxicity by modulating ROS-mediated oxidative stress, mitochondrial dysfunction and caspase signal pathway in rat liver and kidney. Pesticide biochemistry and physiology. 2019 Sep; 159(?):163-172. doi: 10.1016/j.pestbp.2019.06.010. [PMID: 31400778]
  • Ajaz Ahmad, Atif Zafar, Masood Ahmad. Mitigating effects of apigenin on edifenphos-induced oxidative stress, DNA damage and apoptotic cell death in human peripheral blood lymphocytes. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2019 May; 127(?):218-227. doi: 10.1016/j.fct.2019.03.034. [PMID: 30910686]
  • Ajaz Ahmad, Masood Ahmad. Understanding the fate of human serum albumin upon interaction with edifenphos: Biophysical and biochemical approaches. Pesticide biochemistry and physiology. 2018 Feb; 145(?):46-55. doi: 10.1016/j.pestbp.2018.01.006. [PMID: 29482731]
  • Ling-An Kong, Jun Yang, Guo-Tian Li, Lin-Lu Qi, Yu-Jun Zhang, Chen-Fang Wang, Wen-Sheng Zhao, Jin-Rong Xu, You-Liang Peng. Different chitin synthase genes are required for various developmental and plant infection processes in the rice blast fungus Magnaporthe oryzae. PLoS pathogens. 2012 Feb; 8(2):e1002526. doi: 10.1371/journal.ppat.1002526. [PMID: 22346755]
  • K S el-Gendy, N M Aly, A H el-Sebae. Effects of edifenphos and glyphosate on the immune response and protein biosynthesis of bolti fish (Tilapia nilotica). Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1998 Mar; 33(2):135-49. doi: 10.1080/03601239809373135. [PMID: 9536512]
  • A B Din, O Yarden. The Neurospora crassa chs-2 gene encodes a non-essential chitin synthase. Microbiology (Reading, England). 1994 Sep; 140 ( Pt 9)(?):2189-97. doi: 10.1099/13500872-140-9-2189. [PMID: 7952169]
  • J M Poul. Biochemical changes in liver and plasma of rats after oral administration of edifenphos. Toxicology letters. 1983 Apr; 16(1-2):31-4. doi: 10.1016/0378-4274(83)90006-1. [PMID: 6836611]