FENITROTHION (BioDeep_00001871685)
代谢物信息卡片
化学式: C9H12NO5PS (277.0174)
中文名称: 杀螟硫磷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C=CC(=C1)OP(=S)(OC)OC)[N+](=O)[O-]
InChI: InChI=1S/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3
描述信息
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
D010575 - Pesticides > D007306 - Insecticides
D004791 - Enzyme Inhibitors
C471 - Enzyme Inhibitor
D016573 - Agrochemicals
同义名列表
2 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:34757
- PubChem: 31200
- ChEMBL: CHEMBL347698
- MeSH: Fenitrothion
- CAS: 122-14-5
- RefMet: Fenitrothion
- KEGG: C14442
- PubChem: 17395442
- KNApSAcK: 34757
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Seham M Hamed, Marwa Yousry A Mohamed, Badriah Saleh Alammari, Hamada AbdElgawad. Insights into the growth and biochemical defense responses associated with fenitrothion toxicity and uptake by freshwater cyanobacteria.
Chemosphere.
2024 Jun; 358(?):141909. doi:
10.1016/j.chemosphere.2024.141909
. [PMID: 38593960] - Yifan Wang, Mengru An, Kelly M Stevens, Nannan Liu. Insecticide Resistance in Alabama Populations of the Mosquito Aedes albopictus.
Journal of medical entomology.
2022 09; 59(5):1678-1686. doi:
10.1093/jme/tjac085
. [PMID: 35851609] - Yasmina M Abd-Elhakim, Gihan G Moustafa, Nabela I El-Sharkawy, Mohamed M A Hussein, Mervat H Ghoneim, Maha M El Deib. The ameliorative effect of curcumin on hepatic CYP1A1 and CYP1A2 genes dysregulation and hepatorenal damage induced by fenitrothion oral intoxication in male rats.
Pesticide biochemistry and physiology.
2021 Nov; 179(?):104959. doi:
10.1016/j.pestbp.2021.104959
. [PMID: 34802538] - Kien Hong Trinh, Ulhas Sopanrao Kadam, Jinnan Song, Yuhan Cho, Chang Ho Kang, Kyun Oh Lee, Chae Oh Lim, Woo Sik Chung, Jong Chan Hong. Novel DNA Aptameric Sensors to Detect the Toxic Insecticide Fenitrothion.
International journal of molecular sciences.
2021 Oct; 22(19):. doi:
10.3390/ijms221910846
. [PMID: 34639187] - Sadia Sharmin, Md Touhidul Islam, Md Anwar Sadat, Rayeda Jannat, Md Rushna Alam, Md Shahjahan. Sumithion induced structural erythrocyte alteration and damage to the liver and kidney of Nile tilapia.
Environmental science and pollution research international.
2021 Jul; 28(27):36695-36706. doi:
10.1007/s11356-021-13263-4
. [PMID: 33694120] - Khairy A Ibrahim, Hala A Abdelgaid, Mohamed Ali El-Desouky, Abdelgawad Ali Fahmi, Mohamed M Abdel-Daim. Linseed ameliorates renal apoptosis in rat fetuses induced by single or combined exposure to diesel nanoparticles or fenitrothion by inhibiting transcriptional activation of p21/p53 and caspase-3/9 through pro-oxidant stimulus.
Environmental toxicology.
2021 May; 36(5):958-974. doi:
10.1002/tox.23097
. [PMID: 33393722] - Sayed M Badawy. Optimization of reaction time for detection of organophosphorus pesticides by enzymatic inhibition assay and mathematical modeling of enzyme inhibition.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2021; 56(2):142-149. doi:
10.1080/03601234.2020.1853455
. [PMID: 33287632] - Marta Spochacz, Monika Szymczak, Szymon Chowański, Sabino Aurelio Bufo, Zbigniew Adamski. Solanum Nigrum Fruit Extract Increases Toxicity of Fenitrothion-A Synthetic Insecticide, in the Mealworm Beetle Tenebrio Molitor Larvae.
Toxins.
2020 09; 12(10):. doi:
10.3390/toxins12100612
. [PMID: 32987787] - Rashad Rasool Khan, Thuwaini Hashil Abdullah Al-Ghafri, Salim Ali Humaid Al-Khatri, Ibtisam Salim Suliman Al-Mazidi, Fatma Gharib Al-Rawahi. Resistance to deltamethrin and fenitrothion in dubas bug, Ommatissus lybicus de Bergevin (Homoptera: Tropiduchidae) and possible biochemical mechanisms.
Scientific reports.
2020 08; 10(1):13220. doi:
10.1038/s41598-020-70150-7
. [PMID: 32764706] - Atef M K Nassar, Yehia M M Salim, Khalid S A Eid, Hazem M Shaheen, Abdullah A Saati, Helal F Hetta, Amr Elmistekawy, Gaber El-Saber Batiha. Ameliorative Effects of Honey, Propolis, Pollen, and Royal Jelly Mixture against Chronic Toxicity of Sumithion Insecticide in White Albino Rats.
Molecules (Basel, Switzerland).
2020 Jun; 25(11):. doi:
10.3390/molecules25112633
. [PMID: 32517066] - Khairy A Ibrahim, Mohammed Eleyan, Heba Ali Abd El-Rahman, Soad A Khwanes, Rania A Mohamed. Quercetin Attenuates the Oxidative Injury-Mediated Upregulation of Apoptotic Gene Expression and Catecholaminergic Neurotransmitters of the Fetal Rats' Brain Following Prenatal Exposure to Fenitrothion Insecticide.
Neurotoxicity research.
2020 Apr; 37(4):871-882. doi:
10.1007/s12640-020-00172-6
. [PMID: 32034696] - Rasha T Alam, Tamer S Imam, Azza M A Abo-Elmaaty, Ahmed Hamed Arisha. Amelioration of fenitrothion induced oxidative DNA damage and inactivation of caspase-3 in the brain and spleen tissues of male rats by N-acetylcysteine.
Life sciences.
2019 Aug; 231(?):116534. doi:
10.1016/j.lfs.2019.06.009
. [PMID: 31173782] - Rashad Rasool Khan, Salim Ali Humaid Al-Khatri, Thuwaini Hashil Abdullah Al-Ghafri, Ibtisam Salim Suliman Al-Mazidi, Fatima Gharib Al-Rawahi, Saif Suliman Al-Jabri, Muhammad Hammad Hussain. Susceptibility survey of Ommatissus lybicus (de Bergevin) populations against deltamethrin and fenitrothion in Oman.
Scientific reports.
2019 08; 9(1):11690. doi:
10.1038/s41598-019-48244-8
. [PMID: 31406297] - Azza A A Galal, Raghda A Ramadan, Mohamed M M Metwally, Sawsan M A El-Sheikh. Protective effect of N-acetylcysteine on fenitrothion-induced toxicity: The antioxidant status and metabolizing enzymes expression in rats.
Ecotoxicology and environmental safety.
2019 Apr; 171(?):502-510. doi:
10.1016/j.ecoenv.2019.01.004
. [PMID: 30639957] - Fatma M El-Demerdash, Ali B Jebur, Hoda M Nasr, Hanin M Hamid. Modulatory effect of Turnera diffusa against testicular toxicity induced by fenitrothion and/or hexavalent chromium in rats.
Environmental toxicology.
2019 Mar; 34(3):330-339. doi:
10.1002/tox.22688
. [PMID: 30578656] - Hong Liu, Yifang Wan, Yuxin Wang, Yue Zhao, Yue Zhang, Ao Zhang, Qiang Weng, Meiyu Xu. Walnut Polyphenol Extract Protects against Fenitrothion-Induced Immunotoxicity in Murine Splenic Lymphocytes.
Nutrients.
2018 Nov; 10(12):. doi:
10.3390/nu10121838
. [PMID: 30513644] - Marija D Milošević, Milica G Paunović, Miloš M Matić, Branka I Ognjanović, Zorica S Saičić. Role of selenium and vitamin C in mitigating oxidative stress induced by fenitrothion in rat liver.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Oct; 106(?):232-238. doi:
10.1016/j.biopha.2018.06.132
. [PMID: 29966965] - Yong-Zhe Zhu, Min Fu, In-Hong Jeong, Jeong-Han Kim, Chuan-Jie Zhang. Metabolism of an Insecticide Fenitrothion by Cunninghamella elegans ATCC36112.
Journal of agricultural and food chemistry.
2017 Dec; 65(49):10711-10718. doi:
10.1021/acs.jafc.7b04273
. [PMID: 29144738] - Marija D Milošević, Milica G Paunović, Miloš M Matić, Branka I Ognjanović, Zorica S Saičić. The ameliorating effects of selenium and vitamin C against fenitrothion-induced blood toxicity in Wistar rats.
Environmental toxicology and pharmacology.
2017 Dec; 56(?):204-209. doi:
10.1016/j.etap.2017.09.016
. [PMID: 28961515] - Tatsunori Takayasu, Hiroki Yamamoto, Yuko Ishida, Mizuho Nosaka, Mariko Kawaguchi, Yumi Kuninaka, Akihiko Kimura, Toshikazu Kondo. Postmortem distribution of chlorpyrifos-methyl, fenitrothion, and their metabolites in body fluids and organ tissues of an intoxication case.
Legal medicine (Tokyo, Japan).
2017 Nov; 29(?):44-50. doi:
10.1016/j.legalmed.2017.10.002
. [PMID: 29054069] - Sanjeev Kumar Dhungana, Il-Doo Kim, Hwa-Sook Kwak, Dong-Hyun Shin. Unraveling the effect of structurally different classes of insecticide on germination and early plant growth of soybean [Glycine max (L.) Merr].
Pesticide biochemistry and physiology.
2016 Jun; 130(?):39-43. doi:
10.1016/j.pestbp.2015.12.002
. [PMID: 27155482] - T M Saber, R M Abd El-Aziz, H A Ali. Quercetin mitigates fenitrothion-induced testicular toxicity in rats.
Andrologia.
2016 Jun; 48(5):491-500. doi:
10.1111/and.12467
. [PMID: 26264430] - Jean-Martin Lapointe, Patricia A Snyder, William J Reagan. Evaluation of urinary corticosterone as a biomarker of stress in rats using fenitrothion as a chemical stressor.
Journal of immunotoxicology.
2016 05; 13(3):386-92. doi:
10.3109/1547691x.2015.1106623
. [PMID: 27297964] - Hirotaka Sato, Yuki Ito, Jun Ueyama, Yuya Kano, Tomoya Arakawa, Masahiro Gotoh, Takaaki Kondo, Yuka Sugiura, Isao Saito, Eiji Shibata, Michihiro Kamijima. Effects of Paraoxonase 1 gene polymorphisms on organophosphate insecticide metabolism in Japanese pest control workers.
Journal of occupational health.
2016; 58(1):56-65. doi:
10.1539/joh.15-0175-oa
. [PMID: 26549836] - Paul G Story, Kris French, Lee B Astheimer, William A Buttemer. Fenitrothion, an organophosphorous insecticide, impairs locomotory function and alters body temperatures in Sminthopsis macroura (Gould 1845) without reducing metabolic rates during running endurance and thermogenic performance tests.
Environmental toxicology and chemistry.
2016 Jan; 35(1):152-62. doi:
10.1002/etc.3168
. [PMID: 26184692] - Mohamed Ahmed Ibrahim Ahmed, Christoph F A Vogel, Fumio Matsumura. Unique biochemical and molecular biological mechanism of synergistic actions of formamidine compounds on selected pyrethroid and neonicotinoid insecticides on the fourth instar larvae of Aedes aegypti (Diptera: Culicidae).
Pesticide biochemistry and physiology.
2015 May; 120(?):57-63. doi:
10.1016/j.pestbp.2015.01.008
. [PMID: 25987221] - S Lavarías, C F García. Acute toxicity of organophosphate fenitrothion on biomarkers in prawn Palaemonetes argentinus (Crustacea: Palaemonidae).
Environmental monitoring and assessment.
2015 Mar; 187(3):65. doi:
10.1007/s10661-014-4224-5
. [PMID: 25647787] - Kanako Tago, Takashi Okubo, Hideomi Itoh, Yoshitomo Kikuchi, Tomoyuki Hori, Yuya Sato, Atsushi Nagayama, Kentaro Hayashi, Seishi Ikeda, Masahito Hayatsu. Insecticide-degrading Burkholderia symbionts of the stinkbug naturally occupy various environments of sugarcane fields in a Southeast island of Japan.
Microbes and environments.
2015; 30(1):29-36. doi:
10.1264/jsme2.me14124
. [PMID: 25736865] - Sandra E Hernández, Conrad Sernia, Adrian J Bradley. Effect of atrazine and fenitrothion at no-observed-effect-levels (NOEL) on amphibian and mammalian corticosterone-binding-globulin (CBG).
Toxicology letters.
2014 Nov; 230(3):408-12. doi:
10.1016/j.toxlet.2014.08.015
. [PMID: 25138046] - Putri Ayu Jayusman, Siti Balkis Budin, Ahmad Rohi Ghazali, Izatus Shima Taib, Santhana Raj Louis. Effects of palm oil tocotrienol-rich fraction on biochemical and morphological alterations of liver in fenitrothion-treated rats.
Pakistan journal of pharmaceutical sciences.
2014 Nov; 27(6):1873-80. doi:
. [PMID: 25362611]
- Eman A Abd El-Gawad, Omnia M Abdel Hamid. Effect of vitamin C dietary supplementation in reducing the alterations induced by fenitrothion in Oreochromis niloticus.
Fish physiology and biochemistry.
2014 Jun; 40(3):787-96. doi:
10.1007/s10695-013-9885-4
. [PMID: 24197701] - Himiko Suzuki, Yuki Ito, Yuki Noro, Mamoru Koketsu, Michihiro Kamijima, Motohiro Tomizawa. Organophosphate agents induce plasma hypertriglyceridemia in mouse via single or dual inhibition of the endocannabinoid hydrolyzing enzyme(s).
Toxicology letters.
2014 Feb; 225(1):153-7. doi:
10.1016/j.toxlet.2013.12.004
. [PMID: 24361246] - Xiangjiang Tang, Bo Liang, Tuyong Yi, Giuseppe Manco, Ilaria Palchetti, Ilariapalchetti, Aihua Liu. Cell surface display of organophosphorus hydrolase for sensitive spectrophotometric detection of p-nitrophenol substituted organophosphates.
Enzyme and microbial technology.
2014 Feb; 55(?):107-12. doi:
10.1016/j.enzmictec.2013.10.006
. [PMID: 24411452] - Kentaro Kitamura, Kaori Maruyama, Sachiko Hamano, Tomohiro Kishi, Tsuyoshi Kawakami, Yasuo Takahashi, Sukeo Onodera. Effect of hypochlorite oxidation on cholinesterase-inhibition assay of acetonitrile extracts from fruits and vegetables for monitoring traces of organophosphate pesticides.
The Journal of toxicological sciences.
2014 Feb; 39(1):71-81. doi:
10.2131/jts.39.71
. [PMID: 24418711] - Izatus Shima Taib, Siti Balkis Budin, Ahmad Rohi Ghazali, Putri Ayu Jayusman, Jamaludin Mohamed. Fenitrothion alters sperm characteristics in rats: ameliorating effects of palm oil tocotrienol-rich fraction.
Experimental animals.
2014; 63(4):383-93. doi:
10.1538/expanim.63.383
. [PMID: 25030881] - A P Rodrigues, C Gravato, L Guimarães. Involvement of the antioxidant system in differential sensitivity of Carcinus maenas to fenitrothion exposure.
Environmental science. Processes & impacts.
2013 Oct; 15(10):1938-48. doi:
10.1039/c3em00367a
. [PMID: 24056931] - S Lavarías, C García, R Crespo, N Pedrini, H Heras. Study of biochemical biomarkers in freshwater prawn Macrobrachium borellii (Crustacea: Palaemonidae) exposed to organophosphate fenitrothion.
Ecotoxicology and environmental safety.
2013 Oct; 96(?):10-6. doi:
10.1016/j.ecoenv.2013.05.040
. [PMID: 23876938] - Shoetsu Chiba, Toru Ikawa, Hiroshi Takeshita, Sanae Kanno, Tomonori Nagai, Meri Takada, Toshiji Mukai, Michael F Wempe. Human organic cation transporter 2 (hOCT2): Inhibitor studies using S2-hOCT2 cells.
Toxicology.
2013 Aug; 310(?):98-103. doi:
10.1016/j.tox.2013.06.001
. [PMID: 23770354] - Hiromi Ikeura, Sadahiro Hamasaki, Masahiko Tamaki. Effects of ozone microbubble treatment on removal of residual pesticides and quality of persimmon leaves.
Food chemistry.
2013 May; 138(1):366-71. doi:
10.1016/j.foodchem.2012.09.139
. [PMID: 23265500] - Izatus Shima Taib, Siti Balkis Budin, Ahmad Rohi Ghazali, Putri Ayu Jayusman, Santhana Raj Louis, Jamaludin Mohamed. Fenitrothion induced oxidative stress and morphological alterations of sperm and testes in male Sprague-Dawley rats.
Clinics (Sao Paulo, Brazil).
2013 Jan; 68(1):93-100. doi:
10.6061/clinics/2013(01)oa15
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Roczniki Panstwowego Zakladu Higieny.
2013; 64(1):25-9. doi:
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Environment international.
2012 Nov; 48(?):109-20. doi:
10.1016/j.envint.2012.07.007
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Environmental toxicology.
2012 Nov; 27(11):653-61. doi:
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Environment international.
2012 Oct; 47(?):28-36. doi:
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Analytica chimica acta.
2012 Sep; 743(?):137-44. doi:
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. [PMID: 22882834] - El-Maghraby Somia, Farghaly Madiha. Pathological effects of dichlorvos and fenitrothion in mice.
Pathology, research and practice.
2012 May; 208(5):286-91. doi:
10.1016/j.prp.2012.01.010
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Toxicology letters.
2012 Apr; 210(2):220-4. doi:
10.1016/j.toxlet.2011.10.008
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Journal of Zhejiang University. Science. B.
2012 Apr; 13(4):318-26. doi:
10.1631/jzus.b1100318
. [PMID: 22467373] - Fatma M El-Demerdash. Cytotoxic effect of fenitrothion and lambda-cyhalothrin mixture on lipid peroxidation and antioxidant defense system in rat kidney.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2012; 47(4):262-8. doi:
10.1080/03601234.2012.636589
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Parasites & vectors.
2011 Dec; 4(?):236. doi:
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Clinical toxicology (Philadelphia, Pa.).
2011 Nov; 49(9):820-7. doi:
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Journal of AOAC International.
2011 Nov; 94(6):1911-7. doi:
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Archives of oral biology.
2011 Nov; 56(11):1339-46. doi:
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Legal medicine (Tokyo, Japan).
2011 Jul; 13(4):180-5. doi:
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Journal of the American Mosquito Control Association.
2011 Jun; 27(2):129-34. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2011 Jun; 49(6):1346-52. doi:
10.1016/j.fct.2011.03.018
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Journal of biochemical and molecular toxicology.
2011 May; 25(3):169-74. doi:
10.1002/jbt.20373
. [PMID: 20957683] - Andrew D Southam, Anke Lange, Adam Hines, Elizabeth M Hill, Yoshinao Katsu, Taisen Iguchi, Charles R Tyler, Mark R Viant. Metabolomics reveals target and off-target toxicities of a model organophosphate pesticide to roach (Rutilus rutilus): implications for biomonitoring.
Environmental science & technology.
2011 Apr; 45(8):3759-67. doi:
10.1021/es103814d
. [PMID: 21410251] - Takeshi Saito, Tomokazu Fukushima, Yuko Yui, Shota Miyazaki, Akihiro Nakamoto, Akira Namera, Sadaki Inokuchi. Monolithic spin column extraction and GC-MS for the simultaneous assay of diquat, paraquat, and fenitrothion in human serum and urine.
Analytical and bioanalytical chemistry.
2011 Apr; 400(1):25-31. doi:
10.1007/s00216-010-4633-4
. [PMID: 21221537] - Justina Ukpebor, Valon Llabjani, Francis L Martin, Crispin J Halsall. Sublethal genotoxicity and cell alterations by organophosphorus pesticides in MCF-7 cells: implications for environmentally relevant concentrations.
Environmental toxicology and chemistry.
2011 Mar; 30(3):632-9. doi:
10.1002/etc.417
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Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2011; 27(10):999-1005. doi:
10.2116/analsci.27.999
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PloS one.
2011; 6(9):e24430. doi:
10.1371/journal.pone.0024430
. [PMID: 21915326] - Joana R Almeida, Cristiana Oliveira, Carlos Gravato, Lúcia Guilhermino. Linking behavioural alterations with biomarkers responses in the European seabass Dicentrarchus labrax L. exposed to the organophosphate pesticide fenitrothion.
Ecotoxicology (London, England).
2010 Nov; 19(8):1369-81. doi:
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Journal of agricultural and food chemistry.
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