IDAZOXAN (BioDeep_00001871443)

Main id: BioDeep_00000008418

 


代谢物信息卡片


IDAZOXAN

化学式: C11H12N2O2 (204.0899)
中文名称: 亚达唑散
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CN=C(N1)C2COC3=CC=CC=C3O2
InChI: InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)

描述信息

C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists

同义名列表

2 个代谢物同义名

IDAZOXAN; Idazoxan



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ADRA1A, ADRA2A, CA1, CA3, DBH, GFAP, POMC, PRL, TH
Nucleus 3 ADRA1A, PRL, TH
cytosol 6 ADRA1A, CA1, CA3, GFAP, PRKCQ, TH
dendrite 5 DRD2, HTR1A, HTR2A, MAOB, TH
nucleoplasm 2 ADRA1A, PRL
RNA polymerase II transcription regulator complex 1 PRL
Cell membrane 8 ADRA1A, ADRA2A, ADRB3, DRD2, HTR1A, HTR2A, OPRD1, TNF
Cytoplasmic side 1 MAOB
Cell projection, axon 2 HTR2A, TH
Multi-pass membrane protein 7 ADRA1A, ADRA2A, ADRB3, DRD2, HTR1A, HTR2A, OPRD1
Golgi apparatus membrane 1 DRD2
Synapse 4 DBH, DRD2, HTR1A, TAC1
cell surface 1 TNF
dendritic shaft 1 HTR2A
glutamatergic synapse 3 ADRA2A, DRD2, HTR2A
Golgi apparatus 1 NPY
Golgi membrane 2 DRD2, INS
neuronal cell body 5 ADRA2A, HTR2A, MAOB, TAC1, TNF
presynaptic membrane 3 DRD2, HTR2A, OPRD1
smooth endoplasmic reticulum 1 TH
synaptic vesicle 1 TH
Presynapse 1 HTR2A
acrosomal vesicle 1 DRD2
plasma membrane 9 ADRA1A, ADRA2A, ADRB3, DRD2, HTR1A, HTR2A, OPRD1, PRKCQ, TNF
synaptic vesicle membrane 2 DRD2, OPRD1
terminal bouton 1 TH
Membrane 2 DBH, OPRD1
axon 4 DRD2, HTR2A, TAC1, TH
basolateral plasma membrane 1 ADRA2A
caveola 2 ADRA1A, HTR2A
extracellular exosome 1 CA1
endoplasmic reticulum 1 DBH
extracellular space 7 DBH, INS, NPY, POMC, PRL, TAC1, TNF
perinuclear region of cytoplasm 1 TH
mitochondrion 2 MAOB, TH
intracellular membrane-bounded organelle 2 ADRA1A, DBH
Secreted 5 DBH, INS, NPY, POMC, PRL
extracellular region 7 DBH, INS, NPY, POMC, PRL, TAC1, TNF
cytoplasmic side of plasma membrane 1 TH
Mitochondrion outer membrane 1 MAOB
mitochondrial outer membrane 1 MAOB
astrocyte end-foot 1 GFAP
centriolar satellite 2 DBH, PRKCQ
ciliary membrane 1 DRD2
Nucleus membrane 1 ADRA1A
nuclear membrane 1 ADRA1A
external side of plasma membrane 1 TNF
dendritic spine 1 DRD2
perikaryon 2 DRD2, TH
cytoplasmic vesicle 2 HTR2A, TH
Melanosome membrane 1 TH
recycling endosome 1 TNF
Single-pass type II membrane protein 2 DBH, TNF
postsynaptic membrane 2 DRD2, HTR2A
presynaptic active zone membrane 1 ADRA2A
Cytoplasm, perinuclear region 1 TH
Membrane raft 1 TNF
GABA-ergic synapse 3 ADRA2A, DRD2, NPY
secretory granule 1 POMC
intermediate filament 1 GFAP
lateral plasma membrane 1 DRD2
receptor complex 2 ADRA2A, ADRB3
neuron projection 2 OPRD1, TH
cilium 1 DRD2
chromatin 1 PRL
cell projection 1 GFAP
phagocytic cup 1 TNF
non-motile cilium 1 DRD2
sperm flagellum 1 DRD2
endosome lumen 2 INS, PRL
Membrane, caveola 2 ADRA1A, HTR2A
cell body fiber 1 HTR2A
Cell projection, dendrite 2 HTR1A, HTR2A
cell body 1 GFAP
intermediate filament cytoskeleton 1 GFAP
secretory granule lumen 3 DBH, INS, POMC
secretory granule membrane 1 DBH
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
axon terminus 3 ADRA2A, DRD2, OPRD1
endocytic vesicle 1 DRD2
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
mitochondrial envelope 1 MAOB
postsynaptic density membrane 2 ADRA2A, OPRD1
immunological synapse 1 PRKCQ
neuronal dense core vesicle 2 NPY, OPRD1
aggresome 1 PRKCQ
Single-pass type IV membrane protein 1 MAOB
neurofilament 1 HTR2A
dopaminergic synapse 2 ADRA2A, DRD2
dendrite membrane 1 OPRD1
Cytoplasmic vesicle, secretory vesicle membrane 1 DBH
cytoplasmic side of lysosomal membrane 1 GFAP
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen 1 DBH
chromaffin granule lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle 1 NPY
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
transport vesicle membrane 1 DBH
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane 1 DBH
chromaffin granule membrane 1 DBH
G protein-coupled receptor complex 1 DRD2
G protein-coupled serotonin receptor complex 1 HTR2A
spine apparatus 1 OPRD1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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  • Daniel Cussac, Stéphane Schaak, Céline Gales, Christodoulos Flordellis, Colette Denis, Hervé Paris. alpha(2B)-Adrenergic receptors activate MAPK and modulate proliferation of primary cultured proximal tubule cells. American journal of physiology. Renal physiology. 2002 May; 282(5):F943-52. doi: 10.1152/ajprenal.0108.2001. [PMID: 11934705]
  • Xinhui Li, Dawn Conklin, Weiya Ma, Xiaoying Zhu, James C Eisenach. Spinal noradrenergic activation mediates allodynia reduction from an allosteric adenosine modulator in a rat model of neuropathic pain. Pain. 2002 May; 97(1-2):117-25. doi: 10.1016/s0304-3959(02)00011-8. [PMID: 12031785]
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