N,N-Dimethyladenosine (BioDeep_00001869166)

Main id: BioDeep_00000005201

 


代谢物信息卡片


N6,N6-Dimethyladenosine

  化学式: C12H17N5O4 (295.128)
中文名称: 6-二甲基氨基嘌呤-9-核糖苷
  谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)O)O
InChI: InChI=1S/C12H17N5O4/c1-16(2)10-7-11(14-4-13-10)17(5-15-7)12-9(20)8(19)6(3-18)21-12/h4-6,8-9,12,18-20H,3H2,1-2H3/t6-,8-,9-,12-/m1/s1


描述信息

N6,N6-Dimethyladenosine is a modified ribonucleoside previously found in rRNA, and also exhibits in mycobacterium bovis Bacille Calmette-Guérin tRNA[1].

同义名列表

31 个代谢物同义名

N6,N6-Dimethyladenosine; N,N-Dimethyladenosine; N6,N6-Dimethyladenosine; (2R,3R,4S,5R)-2-(6-(Dimethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; (2R,3R,4S,5R)-2-(6-(DIMETHYLAMINO)PURIN-9-YL)-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL; (2R,3R,4S,5R)-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol; (2R,3R,4S,5R)-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 0L9766EW9W; 26A; 6-(Dimethylamino)purine ribonucleoside; 6-(Dimethylamino)purine riboside; 6-(gamma,gamma-dimethylamino)purine riboside; 6-Dimethyladenosine; 6-Dimethylamino-9-(b-D-ribofuranosyl)purine; 6-dimethylamino-9-(beta-d-ribofuranosyl)purine; 6-Dimethylaminopurine 9-riboside; 6-Dimethylaminopurine D-riboside; 6-dimethylaminopurine riboside; 6-Dimethylaminopurine-9-riboside; 6-N-Dimethyladenosine; 6N-DIMETHYLADENOSINE; Adenosine, N,N-dimethyl-; adenosine, N(6),N(6)-dimethyl-; Adenosine,N,N-dimethyl-; N,N-DIMETHYL-9-.BETA.-D-RIBOFURANOSYL-9H-PURINE-6-AMINE; N,N-DIMETHYL-9-BETA-D-RIBOFURANOSYL-9H-PURINE-6-AMINE; N,N-Dimethyl-9-pentofuranosyl-9H-purin-6-amine; N,N-Dimethyladenosine; 6-(Dimethylamino)purineribonucleoside; 6-Dimethylaminopurine-9-riboside; N(6),N(6)-dimethyladenosine; N6-Dimethyladenosine; UNII-0L9766EW9W



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ACE2, ADAM17, ALB, ALKBH3, BUD23, FTO, METTL3, PVR, RPS14
Endosome membrane 2 HLA-A, HLA-B
Endoplasmic reticulum membrane 5 BSG, HLA-A, HLA-B, HLA-C, TAPBP
Nucleus 8 ADK, ALB, ALKBH3, BUD23, FTO, METTL3, TRMT6, ZC3H13
cytosol 8 ADAM17, ADK, ALB, ALKBH3, DIMT1, FTO, METTL3, RPS14
nuclear body 1 METTL3
centrosome 1 ALB
nucleoplasm 9 ADK, ALKBH3, BUD23, DIMT1, FTO, METTL3, RPS14, TRMT6, ZC3H13
Cell membrane 7 ACE2, ADAM17, BSG, DPP4, HLA-A, HLA-B, HLA-C
lamellipodium 1 DPP4
Early endosome membrane 3 HLA-A, HLA-B, HLA-C
cell junction 1 DPP4
cell surface 8 ACE2, ADAM17, DPP4, HLA-A, HLA-B, HLA-C, NECTIN2, PVR
Golgi apparatus 5 ALB, HLA-A, HLA-B, HLA-C, METTL3
Golgi membrane 6 ADAM17, BSG, HLA-A, HLA-B, HLA-C, TAPBP
lysosomal membrane 3 DPP4, HLA-A, HLA-B
sarcolemma 1 BSG
endosome 1 BSG
plasma membrane 11 ACE2, ADAM17, ADK, BSG, DPP4, FTO, HLA-A, HLA-B, HLA-C, NECTIN2, PVR
Membrane 12 ACE2, ADAM17, BSG, DPP4, HLA-A, HLA-B, HLA-C, NECTIN2, PVR, RPS14, TAPBP, ZC3H13
apical plasma membrane 3 ACE2, ADAM17, DPP4
basolateral plasma membrane 1 BSG
extracellular exosome 9 ACE2, ALB, BSG, DPP4, HLA-A, HLA-B, HLA-C, NECTIN2, RPS14
Lysosome membrane 2 HLA-A, HLA-B
endoplasmic reticulum 5 ALB, HLA-A, HLA-B, HLA-C, TAPBP
extracellular space 6 ACE2, ALB, HLA-A, HLA-B, HLA-C, PVR
perinuclear region of cytoplasm 1 BUD23
adherens junction 1 PVR
intercellular canaliculus 1 DPP4
mitochondrion 2 ALKBH3, BSG
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 2 BSG, FTO
postsynaptic density 1 RPS14
Single-pass type I membrane protein 7 ACE2, ADAM17, BSG, HLA-A, HLA-B, HLA-C, TAPBP
Secreted 3 ACE2, ALB, DPP4
extracellular region 3 ACE2, ALB, DPP4
Single-pass membrane protein 5 DPP4, HLA-A, HLA-B, HLA-C, PVR
anchoring junction 2 ALB, DPP4
Cell projection, cilium 1 ACE2
photoreceptor inner segment 1 BSG
photoreceptor outer segment 1 BSG
external side of plasma membrane 3 HLA-A, HLA-B, HLA-C
actin cytoskeleton 1 ADAM17
nucleolus 3 BUD23, DIMT1, RPS14
cell-cell junction 1 NECTIN2
Single-pass type II membrane protein 1 DPP4
Apical cell membrane 2 ACE2, DPP4
Cytoplasm, perinuclear region 1 BUD23
Membrane raft 3 ACE2, ADAM17, DPP4
focal adhesion 5 BSG, DPP4, NECTIN2, PVR, RPS14
zonula adherens 1 NECTIN2
lateral plasma membrane 1 BSG
nuclear speck 3 FTO, METTL3, ZC3H13
ciliary basal body 1 ALB
cilium 1 ACE2
phagocytic vesicle membrane 4 HLA-A, HLA-B, HLA-C, TAPBP
centriole 1 ALB
Cell projection, cilium, photoreceptor outer segment 1 BSG
brush border membrane 1 ACE2
Nucleus, nucleolus 2 DIMT1, RPS14
spindle pole 1 ALB
blood microparticle 1 ALB
Basolateral cell membrane 1 BSG
[Isoform 2]: Cell membrane 1 BSG
Recycling endosome membrane 3 HLA-A, HLA-B, HLA-C
Endomembrane system 2 DPP4, TAPBP
Nucleus, nucleoplasm 3 BUD23, DIMT1, ZC3H13
Melanosome 1 BSG
Nucleus speckle 3 FTO, METTL3, ZC3H13
secretory granule membrane 2 HLA-B, HLA-C
endoplasmic reticulum lumen 3 ACE2, ADAM17, ALB
platelet alpha granule lumen 1 ALB
endocytic vesicle membrane 1 ACE2
endocytic vesicle 1 DPP4
small-subunit processome 2 DIMT1, RPS14
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 TAPBP
endoplasmic reticulum exit site 1 HLA-A
ER to Golgi transport vesicle membrane 3 HLA-A, HLA-B, HLA-C
[Isoform 2]: Cytoplasm 1 ADK
ribonucleoprotein complex 1 RPS14
[Isoform 1]: Nucleus 1 ADK
lumenal side of endoplasmic reticulum membrane 4 HLA-A, HLA-B, HLA-C, TAPBP
MHC class I peptide loading complex 2 HLA-A, TAPBP
Tapasin-ERp57 complex 1 TAPBP
apical junction complex 1 NECTIN2
[Isoform 1]: Cell membrane 1 BSG
acrosomal membrane 1 BSG
cytosolic ribosome 1 RPS14
cell-cell contact zone 1 NECTIN2
[Isoform 3]: Cell membrane 1 BSG
Golgi medial cisterna 1 HLA-A
lamellipodium membrane 1 DPP4
oxidoreductase complex 1 METTL3
ribosome 1 RPS14
MHC class I protein complex 3 HLA-A, HLA-B, HLA-C
MHC class II protein complex 3 HLA-A, HLA-B, HLA-C
Cell projection, lamellipodium membrane 1 DPP4
Cell projection, invadopodium membrane 1 DPP4
cytosolic small ribosomal subunit 1 RPS14
[Isoform 4]: Cell membrane 1 BSG
[Dipeptidyl peptidase 4 soluble form]: Secreted 1 DPP4
ciliary transition fiber 1 ALB
small ribosomal subunit 1 RPS14
RNA N6-methyladenosine methyltransferase complex 2 METTL3, ZC3H13
tRNA (m1A) methyltransferase complex 1 TRMT6
[Processed angiotensin-converting enzyme 2]: Secreted 1 ACE2
[Isoform 2]: Apical cell membrane 1 ACE2


文献列表

  • E Strzelczyk, M Kampert, L Michalski. Production of cytokinin-like substances by mycorrhizal fungi of pine (Pinus sylvestris L.) in cultures with and without metabolites of actinomycetes. Acta microbiologica Polonica. 1985; 34(2):177-85. doi: ". [PMID: 2412406]