Inositol 1,3,4-trisphosphate (BioDeep_00001868887)
Main id: BioDeep_00000004626
代谢物信息卡片
化学式: C6H15O15P3 (419.9624)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1(C(C(C(C(C1OP(=O)(O)O)O)OP(=O)(O)O)OP(=O)(O)O)O)O
InChI: InChI=1S/C6H15O15P3/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)/t1-,2-,3+,4+,5+,6+/m1/s1
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:18228
- KEGG: C01243
- PubChem: 439455
- DrugBank: DB01729
- ChEMBL: CHEMBL329137
- CAS: 93133-76-7
- MetaboLights: MTBLC18228
- PubChem: 4464
- PDB-CCD: I3S
- 3DMET: B01421
- NIKKAJI: J386.725K
- RefMet: Inositol 1,3,4-trisphosphate
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Zhen Guan, Jianhua Wang, Jin Guo, Fang Wang, Xiuwei Wang, Guannan Li, Qiu Xie, Xu Han, Bo Niu, Ting Zhang. The maternal ITPK1 gene polymorphism is associated with neural tube defects in a high-risk Chinese population.
PloS one.
2014; 9(1):e86145. doi:
10.1371/journal.pone.0086145. [PMID: 24465924] - H Plattner, I M Sehring, I K Mohamed, K Miranda, W De Souza, R Billington, A Genazzani, E-M Ladenburger. Calcium signaling in closely related protozoan groups (Alveolata): non-parasitic ciliates (Paramecium, Tetrahymena) vs. parasitic Apicomplexa (Plasmodium, Toxoplasma).
Cell calcium.
2012 May; 51(5):351-82. doi:
10.1016/j.ceca.2012.01.006. [PMID: 22387010] - Gregory J Miller, Monita P Wilson, Philip W Majerus, James H Hurley. Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase.
Molecular cell.
2005 Apr; 18(2):201-12. doi:
10.1016/j.molcel.2005.03.016. [PMID: 15837423] - J M Kavran, D E Klein, A Lee, M Falasca, S J Isakoff, E Y Skolnik, M A Lemmon. Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains.
The Journal of biological chemistry.
1998 Nov; 273(46):30497-508. doi:
10.1074/jbc.273.46.30497. [PMID: 9804818] - M P Wilson, P W Majerus. Characterization of a cDNA encoding Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase.
Biochemical and biophysical research communications.
1997 Mar; 232(3):678-81. doi:
10.1006/bbrc.1997.6355. [PMID: 9126335] - Z Tan, K S Bruzik, S B Shears. Properties of the inositol 3,4,5,6-tetrakisphosphate 1-kinase purified from rat liver. Regulation of enzyme activity by inositol 1,3,4-trisphosphate.
The Journal of biological chemistry.
1997 Jan; 272(4):2285-90. doi:
10.1074/jbc.272.4.2285. [PMID: 8999935] - G S Bird, J W Putney. Effect of inositol 1,3,4,5-tetrakisphosphate on inositol trisphosphate-activated Ca2+ signaling in mouse lacrimal acinar cells.
The Journal of biological chemistry.
1996 Mar; 271(12):6766-70. doi:
10.1074/jbc.271.12.6766. [PMID: 8636098] - M L Contreras. Nerve growth factor stimulates the production of inositol 1,3,4- and 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate in PC12 cells.
Journal of neurochemistry.
1993 Sep; 61(3):1035-42. doi:
10.1111/j.1471-4159.1993.tb03617.x. [PMID: 8360670] - M Abdullah, P J Hughes, A Craxton, R Gigg, T Desai, J F Marecek, G D Prestwich, S B Shears. Purification and characterization of inositol-1,3,4-trisphosphate 5/6-kinase from rat liver using an inositol hexakisphosphate affinity column.
The Journal of biological chemistry.
1992 Nov; 267(31):22340-5. doi:
. [PMID: 1331051] - R R Mattingly, L R Stephens, R F Irvine, J C Garrison. Effects of transformation with the v-src oncogene on inositol phosphate metabolism in rat-1 fibroblasts. D-myo-inositol 1,4,5,6-tetrakisphosphate is increased in v-src-transformed rat-1 fibroblasts and can be synthesized from D-myo-inositol 1,3,4-trisphosphate in cytosolic extracts.
The Journal of biological chemistry.
1991 Aug; 266(23):15144-53. doi:
. [PMID: 1869546] - M Romano, M Molino, C Cerletti. Endotoxic lipid A induces intracellular Ca2+ increase in human platelets.
The Biochemical journal.
1991 Aug; 278 ( Pt 1)(?):75-80. doi:
10.1042/bj2780075. [PMID: 1909116] - . .
.
. doi:
. [PMID: 22038091]
