GUANOSINE-5-triphosphATE (BioDeep_00001868319)

Main id: BioDeep_00000001617

 

BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


guanosine 5-(tetrahydrogen triphosphate)

化学式: C10H16N5O14P3 (522.9906626)
中文名称: 鸟苷三磷酸, 5'-三磷酸鸟苷三钠三磷酸鸟苷三钠 钠盐 水合物
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
InChI: InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1

描述信息

COVID info from PDB, Protein Data Bank, WikiPathways
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

3 个代谢物同义名

guanosine 5-(tetrahydrogen triphosphate); GUANOSINE-5-triphosphATE; GTP



数据库引用编号

19 个数据库交叉引用编号

分类词条

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sapna I, A Jayadeep. Enzyme-treated red rice (Oryza sativa L.) bran extracts mitigate inflammatory markers in RAW 264.7 macrophage cells and exhibit anti-inflammatory efficacy greater/comparable to ferulic acid, catechin, γ-tocopherol, and γ-oryzanol. Journal of ethnopharmacology. 2024 Apr; 323(?):117616. doi: 10.1016/j.jep.2023.117616. [PMID: 38142877]
  • Lijun Shi, Chenguang Yang, Mingyuan Zhang, Kangning Li, Keying Wang, Li Jiao, Ruming Liu, Yunyun Wang, Ming Li, Yong Wang, Lu Ma, Shuxin Hu, Xin Bian. Dissecting the mechanism of atlastin-mediated homotypic membrane fusion at the single-molecule level. Nature communications. 2024 Mar; 15(1):2488. doi: 10.1038/s41467-024-46919-z. [PMID: 38509071]
  • Mengjie Zhu, Nan Wu, Jiayi Zhong, Chen Chen, Wenwen Liu, Yingdang Ren, Xifeng Wang, Huaibing Jin. N6-methyladenosine modification of the mRNA for a key gene in purine nucleotide metabolism regulates virus proliferation in an insect vector. Cell reports. 2024 Feb; 43(2):113821. doi: 10.1016/j.celrep.2024.113821. [PMID: 38368611]
  • Cody Aplin, Richard A Cerione. Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6. The Journal of biological chemistry. 2023 Dec; 300(2):105608. doi: 10.1016/j.jbc.2023.105608. [PMID: 38159849]
  • Huayin Bao, Wei Wang, Haibo Sun, Jianzhong Chen. Probing mutation-induced conformational transformation of the GTP/M-RAS complex through Gaussian accelerated molecular dynamics simulations. Journal of enzyme inhibition and medicinal chemistry. 2023 Dec; 38(1):2195995. doi: 10.1080/14756366.2023.2195995. [PMID: 37057639]
  • Man Zhang, Wenshuang Wang, Kaixin Liu, Chao Jia, Yuanyuan Hou, Gang Bai. Astragaloside IV protects against lung injury and pulmonary fibrosis in COPD by targeting GTP-GDP domain of RAS and downregulating the RAS/RAF/FoxO signaling pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Nov; 120(?):155066. doi: 10.1016/j.phymed.2023.155066. [PMID: 37690229]
  • Cecilia Rodriguez-Furlan, Ariana Emami, Jaimie M Van Norman. Distinct ADP-ribosylation factor-GTP exchange factors govern the opposite polarity of two receptor kinases. Plant physiology. 2023 Oct; ?(?):. doi: 10.1093/plphys/kiad519. [PMID: 37787604]
  • Junying Li, Xueling Chang, Xiangming Chen, Ruiyu Ma, Renrong Qi, Wei Liu, Yan Li, Yi Wan, Qinqin Qiu, Qiance Shao, Aiqiao Liu, Kai Zhan. Effects of green tea powder on production performance, egg quality, and blood biochemical parameters in laying hens. Poultry science. 2023 Oct; 102(10):102924. doi: 10.1016/j.psj.2023.102924. [PMID: 37542941]
  • Heng Shi, Xinhai Zhao, Peng Qin, Xianling Zhou, Sisi Liu, Chuanchuan Sun, Qiuyu Cao, Shiping Zhu, Shengyun Sun. Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice. American journal of nephrology. 2023 Sep; ?(?):. doi: 10.1159/000534106. [PMID: 37734331]
  • Yanan Wang, Kun Liu, Meishan Lu, Jiachen Shi, Yong-Jiang Xu, Yuanfa Liu. Comparative evaluation of static and dynamic simulated digestion models. Journal of the science of food and agriculture. 2023 Sep; 103(12):5893-5903. doi: 10.1002/jsfa.12692. [PMID: 37144349]
  • Jahanvi Ganotra, Bhawana Sharma, Brijesh Biswal, Deepak Bhardwaj, Narendra Tuteja. Emerging role of small GTPases and their interactome in plants to combat abiotic and biotic stress. Protoplasma. 2023 Jul; 260(4):1007-1029. doi: 10.1007/s00709-022-01830-6. [PMID: 36525153]
  • Tian-Tian Jiang, Cong-Lan Ji, Li-Jun Yu, Meng-Ke Song, Yan Li, Qiang Liao, Tuo Wei, Opeyemi Joshua Olatunji, Jian Zuo, Jun Han. Resveratrol-induced SIRT1 activation inhibits glycolysis-fueled angiogenesis under rheumatoid arthritis conditions independent of HIF-1α. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2023 Apr; ?(?):. doi: 10.1007/s00011-023-01728-w. [PMID: 37016140]
  • Katie J Porter, Lingyan Cao, Katherine W Osteryoung. Dynamics of the Synechococcus elongatus cytoskeletal GTPase FtsZ yields mechanistic and evolutionary insight into cyanobacterial and chloroplast FtsZs. The Journal of biological chemistry. 2023 03; 299(3):102917. doi: 10.1016/j.jbc.2023.102917. [PMID: 36657643]
  • Ian R Fleming, Jonathan P Hannan, George Hayden Swisher, Corey D Tesdahl, Justin G Martyr, Nicholas J Cordaro, Annette H Erbse, Joseph J Falke. Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements. Analytical biochemistry. 2023 02; 663(?):115019. doi: 10.1016/j.ab.2022.115019. [PMID: 36526022]
  • Yongshun Zhou, Fanze Meng, Kai Han, Kaiyue Zhang, Jianfeng Gao, Fulong Chen. Screening and validating of endogenous reference genes in Chlorella sp. TLD 6B under abiotic stress. Scientific reports. 2023 01; 13(1):1555. doi: 10.1038/s41598-023-28311-x. [PMID: 36707665]
  • Yingjie Guo, Huan Zhang, Chen Yan, Birong Shen, Yue Zhang, Xiangyang Guo, Sha Sun, Fan Yu, Jiayun Yan, Ronghe Liu, Qianping Zhang, Di Zhang, Haiyang Liu, Yang Liu, Yaoyao Zhang, Wenlei Li, Jiangyu Qin, He Lv, Zhaoxia Wang, Yun Yuan, Jie-Feng Yang, Ya-Ting Zhong, Song Gao, Bing Zhou, Lei Liu, Deling Kong, Xiaojiang Hao, Junjie Hu, Quan Chen. Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction. Nature chemical biology. 2023 Jan; ?(?):. doi: 10.1038/s41589-022-01224-y. [PMID: 36635564]
  • Qian-Zhi Ni, Bing Zhu, Yan Ji, Qian-Wen Zheng, Xin Liang, Ning Ma, Hao Jiang, Feng-Kun Zhang, Yu-Rong Shang, Yi-Kang Wang, Sheng Xu, Er-Bin Zhang, Yan-Mei Yuan, Tian-Wei Chen, Fen-Fen Yin, Hui-Jun Cao, Jing-Yi Huang, Ji Xia, Xu-Fen Ding, Xiao-Song Qiu, Kai Ding, Chao Song, Wen-Tao Zhou, Meng Wu, Kang Wang, Rui Lui, Qiu Lin, Wei Chen, Zhi-Gang Li, Shu-Qun Cheng, Xiao-Fan Wang, Dong Xie, Jing-Jing Li. PPDPF Promotes the Development of Mutant KRAS-Driven Pancreatic Ductal Adenocarcinoma by Regulating the GEF Activity of SOS1. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023 01; 10(2):e2202448. doi: 10.1002/advs.202202448. [PMID: 36453576]
  • H Y Bao, W Wang, H B Sun, J Z Chen. Binding modes of GDP, GTP and GNP to NRAS deciphered by using Gaussian accelerated molecular dynamics simulations. SAR and QSAR in environmental research. 2023 Jan; 34(1):65-89. doi: 10.1080/1062936x.2023.2165542. [PMID: 36762439]
  • Gianfranco Paccione, Miguel Á Robles-Ramos, Carlos Alfonso, Marta Sobrinos-Sanguino, William Margolin, Silvia Zorrilla, Begoña Monterroso, Germán Rivas. Lipid Surfaces and Glutamate Anions Enhance Formation of Dynamic Biomolecular Condensates Containing Bacterial Cell Division Protein FtsZ and Its DNA-Bound Regulator SlmA. Biochemistry. 2022 11; 61(22):2482-2489. doi: 10.1021/acs.biochem.2c00424. [PMID: 36315857]
  • Di Zhang, Bei Jing, Zhenni Chen, Xin Li, Huimei Shi, Yachun Zheng, Shiquan Chang, Guoping Zhao. Ferulic acid alleviates sciatica by inhibiting peripheral sensitization through the RhoA/p38MAPK signalling pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Nov; 106(?):154420. doi: 10.1016/j.phymed.2022.154420. [PMID: 36115115]
  • Wei Liu, Chunxia G Cronin, Ziming Cao, Chengliang Wang, Jianbin Ruan, Sunitha Pulikkot, Alexxus Hall, Hao Sun, Alex Groisman, Yunfeng Chen, Anthony T Vella, Liang Hu, Bruce T Liang, Zhichao Fan. Nexinhib20 Inhibits Neutrophil Adhesion and β2 Integrin Activation by Antagonizing Rac-1-Guanosine 5'-Triphosphate Interaction. Journal of immunology (Baltimore, Md. : 1950). 2022 10; 209(8):1574-1585. doi: 10.4049/jimmunol.2101112. [PMID: 36165184]
  • Huiling Guo, Juan Wang, Su Ren, Lang-Fan Zheng, Yi-Xuan Zhuang, Dong-Lin Li, Hui-Hui Sun, Li-Ying Liu, Changchuan Xie, Ya-Ying Wu, Hong-Rui Wang, Xianming Deng, Peng Li, Tong-Jin Zhao. Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system. Nature communications. 2022 10; 13(1):6004. doi: 10.1038/s41467-022-33788-7. [PMID: 36224181]
  • Van A Ngo, Angel E Garcia. Millisecond molecular dynamics simulations of KRas-dimer formation and interfaces. Biophysical journal. 2022 10; 121(19):3730-3744. doi: 10.1016/j.bpj.2022.04.026. [PMID: 35462078]
  • Adriana Trutzenberg, Stefan Engelhardt, Lukas Weiß, Ralph Hückelhoven. Barley guanine nucleotide exchange factor HvGEF14 is an activator of the susceptibility factor HvRACB and supports host cell entry by Blumeria graminis f. sp. hordei. Molecular plant pathology. 2022 10; 23(10):1524-1537. doi: 10.1111/mpp.13246. [PMID: 35849420]
  • Guohua Lv, Myung Soo Ko, Tapojyoti Das, David Eliezer. Molecular and functional interactions of alpha-synuclein with Rab3a. The Journal of biological chemistry. 2022 09; 298(9):102239. doi: 10.1016/j.jbc.2022.102239. [PMID: 35809645]
  • Wudtichai Wisuitiprot, Kornkanok Ingkaninan, Sirada Jones, Neti Waranuch. Effect of green tea extract loaded chitosan microparticles on facial skin: A split-face, double-blind, randomized placebo-controlled study. Journal of cosmetic dermatology. 2022 Sep; 21(9):4001-4008. doi: 10.1111/jocd.14707. [PMID: 34965006]
  • Dustin E Bosch, William R Jeck, David P Siderovski. Self-activating G protein α subunits engage seven-transmembrane regulator of G protein signaling (RGS) proteins and a Rho guanine nucleotide exchange factor effector in the amoeba Naegleria fowleri. The Journal of biological chemistry. 2022 08; 298(8):102167. doi: 10.1016/j.jbc.2022.102167. [PMID: 35738399]
  • Kazuhiro Ito, Doshun Ito, Mina Goto, Sae Suzuki, Shinji Masuda, Koh Iba, Kensuke Kusumi. Regulation of ppGpp Synthesis and Its Impact on Chloroplast Biogenesis during Early Leaf Development in Rice. Plant & cell physiology. 2022 Jul; 63(7):919-931. doi: 10.1093/pcp/pcac053. [PMID: 35428891]
  • T Wang, M J Jin, L K Li. [The GTP-Bound form of Rab3D Promotes Lipid Droplet Growth in Adipocyte]. Molekuliarnaia biologiia. 2022 Jul; 56(4):564-573. doi: 10.31857/s0026898422040140. [PMID: 35964313]
  • Negar Shahsavari, Boyuan Wang, Yu Imai, Miho Mori, Sangkeun Son, Libang Liang, Nils Böhringer, Sylvie Manuse, Michael F Gates, Madeleine Morrissette, Rachel Corsetti, Josh L Espinoza, Chris L Dupont, Michael T Laub, Kim Lewis. A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP. mBio. 2022 06; 13(3):e0070022. doi: 10.1128/mbio.00700-22. [PMID: 35575547]
  • Giang Pham, Dong-Min Shin, Yoon Kim, Soo-Hwan Kim. Ran-GTP/-GDP-dependent nuclear accumulation of NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1 and TGACG-BINDING FACTOR2 controls salicylic acid-induced leaf senescence. Plant physiology. 2022 06; 189(3):1774-1793. doi: 10.1093/plphys/kiac164. [PMID: 35417014]
  • Bikram D Pant, Seonghee Lee, Hee-Kyung Lee, Nick Krom, Pooja Pant, YoonJeong Jang, Kirankumar S Mysore. Overexpression of Arabidopsis nucleolar GTP-binding 1 (NOG1) proteins confers drought tolerance in rice. Plant physiology. 2022 06; 189(2):988-1004. doi: 10.1093/plphys/kiac078. [PMID: 35260897]
  • Chen Ling, Xingyong Chen, Weihuang Lin, Zhaoyu Geng. Green tea powder inclusion promoted hatchability through increased yolk antioxidant activity. Poultry science. 2022 May; 101(5):101804. doi: 10.1016/j.psj.2022.101804. [PMID: 35325830]
  • Donghua Jin, Miao Jia, Yuxian Xie, Lihua Lin, Hong Qiu, Guoyuan Lu. Impact of klotho on the expression of SRGAP2a in podocytes in diabetic nephropathy. BMC nephrology. 2022 04; 23(1):151. doi: 10.1186/s12882-022-02765-z. [PMID: 35436879]
  • Kiran S Toti, John R Jimah, Veronica Salmaso, Jenny E Hinshaw, Kenneth A Jacobson. Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin. Biomolecules. 2022 04; 12(4):. doi: 10.3390/biom12040584. [PMID: 35454173]
  • Kunpeng Liu, Dongbo Qiu, Xue Liang, Yingqi Huang, Yao Wang, Xin Jia, Kun Li, Jingyuan Zhao, Cong Du, Xiusheng Qiu, Jun Cui, Zhendong Xiao, Yunfei Qin, Qi Zhang. Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy. Autophagy. 2022 04; 18(4):860-876. doi: 10.1080/15548627.2021.1961072. [PMID: 34382907]
  • Sybille Koehler, Johanna Odenthal, Vivian Ludwig, David Unnersjö Jess, Martin Höhne, Christian Jüngst, Ferdi Grawe, Martin Helmstädter, Johanna L Janku, Carsten Bergmann, Peter F Hoyer, H Henning Hagmann, Gerd Walz, Wilhelm Bloch, Carien Niessen, Bernhard Schermer, Andreas Wodarz, Barry Denholm, Thomas Benzing, Sandra Iden, Paul T Brinkkoetter. Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney international. 2022 04; 101(4):733-751. doi: 10.1016/j.kint.2021.11.030. [PMID: 34929254]
  • Yachana Jha, Budheswar Dehury, S P Jeevan Kumar, Anurag Chaurasia, Udai B Singh, Manoj Kumar Yadav, U B Angadi, Rajiv Ranjan, Minaketan Tripathy, R B Subramanian, Sunil Kumar, Jesus Simal-Gandara. Delineation of molecular interactions of plant growth promoting bacteria induced β-1,3-glucanases and guanosine triphosphate ligand for antifungal response in rice: a molecular dynamics approach. Molecular biology reports. 2022 Apr; 49(4):2579-2589. doi: 10.1007/s11033-021-07059-5. [PMID: 34914086]
  • Kohsuke Yamada, Toru Hyodo, Syunichiro Urabe, Satomi Haga, Toshio Hosaka. Serum YKL-40 Level is Associated with Geriatric Nutritional Risk Index (GNRI) and γ-GTP in Hemodialysis Patients. The journal of medical investigation : JMI. 2022; 69(1.2):101-106. doi: 10.2152/jmi.69.101. [PMID: 35466129]
  • Hiroshi Senoo, Daisuke Murata, May Wai, Kenta Arai, Wakiko Iwata, Hiromi Sesaki, Miho Iijima. KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis. Molecular cell. 2021 11; 81(22):4622-4634.e8. doi: 10.1016/j.molcel.2021.09.001. [PMID: 34551282]
  • Natsumi Maruta, Yuri Trusov, Alan M Jones, Jose R Botella. Heterotrimeric G Proteins in Plants: Canonical and Atypical Gα Subunits. International journal of molecular sciences. 2021 Oct; 22(21):. doi: 10.3390/ijms222111841. [PMID: 34769272]
  • Anna Bianchi-Smiraglia, David W Wolff, Daniel J Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M Wombacher, Ashley L Mussell, Shichen Shen, Jialin Chen, Dong-Hyun Yun, Anderson O'Brien Cox, Cristina M Furdui, Edward Hurley, Maria Laura Feltri, Jun Qu, Thomas Hollis, Jules Berlin Nde Kengne, Bernard Fongang, Rui J Sousa, Mikhail E Kandel, Eugene S Kandel, Klaus M Hahn, Mikhail A Nikiforov. Regulation of local GTP availability controls RAC1 activity and cell invasion. Nature communications. 2021 10; 12(1):6091. doi: 10.1038/s41467-021-26324-6. [PMID: 34667203]
  • Johannes Kattan, Anne Doerr, Marileen Dogterom, Christophe Danelon. Shaping Liposomes by Cell-Free Expressed Bacterial Microtubules. ACS synthetic biology. 2021 10; 10(10):2447-2455. doi: 10.1021/acssynbio.1c00278. [PMID: 34585918]
  • Gonzalo P Solis, Tatyana V Kozhanova, Alexey Koval, Svetlana S Zhilina, Tatyana I Mescheryakova, Aleksandr A Abramov, Evgeny V Ishmuratov, Ekaterina S Bolshakova, Karina V Osipova, Sergey O Ayvazyan, Sébastien Lebon, Ilya V Kanivets, Denis V Pyankov, Sabina Troccaz, Denis N Silachev, Nikolay N Zavadenko, Andrey G Prityko, Vladimir L Katanaev. Pediatric Encephalopathy: Clinical, Biochemical and Cellular Insights into the Role of Gln52 of GNAO1 and GNAI1 for the Dominant Disease. Cells. 2021 10; 10(10):. doi: 10.3390/cells10102749. [PMID: 34685729]
  • Ying Liu, Xiaoyun Wang, Danhui Dong, Luqin Guo, Xiaonan Dong, Jing Leng, Bing Zhao, Yang-Dong Guo, Na Zhang. Research Advances in Heterotrimeric G-Protein α Subunits and Uncanonical G-Protein Coupled Receptors in Plants. International journal of molecular sciences. 2021 Aug; 22(16):. doi: 10.3390/ijms22168678. [PMID: 34445383]
  • Jianzhong Chen, Lifei Wang, Wei Wang, Haibo Sun, Laixue Pang, Huayin Bao. Conformational transformation of switch domains in GDP/K-Ras induced by G13 mutants: An investigation through Gaussian accelerated molecular dynamics simulations and principal component analysis. Computers in biology and medicine. 2021 08; 135(?):104639. doi: 10.1016/j.compbiomed.2021.104639. [PMID: 34247129]
  • Krishnakanth Baratam, Kirtika Jha, Anand Srivastava. Flexible pivoting of dynamin pleckstrin homology domain catalyzes fission: insights into molecular degrees of freedom. Molecular biology of the cell. 2021 07; 32(14):1306-1319. doi: 10.1091/mbc.e20-12-0794. [PMID: 33979205]
  • Linda Sistemich, Lyubomir Dimitrov Stanchev, Miriam Kutsch, Aurélien Roux, Thomas Günther Pomorski, Christian Herrmann. Structural requirements for membrane binding of human guanylate-binding protein 1. The FEBS journal. 2021 07; 288(13):4098-4114. doi: 10.1111/febs.15703. [PMID: 33405388]
  • Natsumi Maruta, Yuri Trusov, Daisuke Urano, David Chakravorty, Sarah M Assmann, Alan M Jones, Jose R Botella. GTP binding by Arabidopsis extra-large G protein 2 is not essential for its functions. Plant physiology. 2021 06; 186(2):1240-1253. doi: 10.1093/plphys/kiab119. [PMID: 33729516]
  • Wenbin Zhou, Bangjie Zhu, Fang Kou, Shenglan Qi, Chunming Lv, Yu Cheng, Hai Wei. Targeted Metabolic Profiling and PRM Analysis of Proteins Revealed Impaired Polyunsaturated Fatty Acid Metabolism and GTP Metabolism in the Brainstem of Spontaneously Hypertensive Rats. Journal of proteome research. 2021 06; 20(6):3305-3314. doi: 10.1021/acs.jproteome.1c00208. [PMID: 33999640]
  • Diego A Ramirez-Diaz, Adrián Merino-Salomón, Fabian Meyer, Michael Heymann, Germán Rivas, Marc Bramkamp, Petra Schwille. FtsZ induces membrane deformations via torsional stress upon GTP hydrolysis. Nature communications. 2021 06; 12(1):3310. doi: 10.1038/s41467-021-23387-3. [PMID: 34083531]
  • Simona Catozzi, Melinda Halasz, Christina Kiel. Predicted 'wiring landscape' of Ras-effector interactions in 29 human tissues. NPJ systems biology and applications. 2021 02; 7(1):10. doi: 10.1038/s41540-021-00170-0. [PMID: 33580066]
  • X Zhou, K Shafique, M Sajid, Q Ali, E Khalili, M A Javed, M S Haider, G Zhou, G Zhu. Era-like GTP protein gene expression in rice. Brazilian journal of biology = Revista brasleira de biologia. 2021; 82(?):e250700. doi: 10.1590/1519-6984.250700. [PMID: 34259718]
  • Soumen Bera, Mubasher Rashid, Alexander B Medvinsky, Gui-Quan Sun, Bai-Lian Li, Claudia Acquisti, Adnan Sljoka, Amit Chakraborty. Allosteric regulation of glutamate dehydrogenase deamination activity. Scientific reports. 2020 10; 10(1):16523. doi: 10.1038/s41598-020-73743-4. [PMID: 33020580]
  • Iker Lamas, Nathalie Weber, Sophie G Martin. Activation of Cdc42 GTPase upon CRY2-Induced Cortical Recruitment Is Antagonized by GAPs in Fission Yeast. Cells. 2020 09; 9(9):. doi: 10.3390/cells9092089. [PMID: 32932721]
  • Wupeng Yan, Evan Markegard, Srisathiyanarayanan Dharmaiah, Anatoly Urisman, Matthew Drew, Dominic Esposito, Klaus Scheffzek, Dwight V Nissley, Frank McCormick, Dhirendra K Simanshu. Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR. Cell reports. 2020 07; 32(3):107909. doi: 10.1016/j.celrep.2020.107909. [PMID: 32697994]
  • Lulu Li, Li Xu, Si Wen, Ying Yang, Xin Li, Qiuling Fan. The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells. Journal of cellular physiology. 2020 07; 235(7-8):5787-5795. doi: 10.1002/jcp.29512. [PMID: 31975379]
  • Ruihui Zhang, Donghoon M Lee, John R Jimah, Nathalie Gerassimov, Changsong Yang, Sangjoon Kim, Delgermaa Luvsanjav, Jonathan Winkelman, Marcel Mettlen, Michael E Abrams, Raghav Kalia, Peter Keene, Pratima Pandey, Benjamin Ravaux, Ji Hoon Kim, Jonathon A Ditlev, Guofeng Zhang, Michael K Rosen, Adam Frost, Neal M Alto, Margaret Gardel, Sandra L Schmid, Tatyana M Svitkina, Jenny E Hinshaw, Elizabeth H Chen. Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein. Nature cell biology. 2020 06; 22(6):674-688. doi: 10.1038/s41556-020-0519-7. [PMID: 32451441]
  • Iván J Bazany-Rodríguez, María K Salomón-Flores, Joanatan M Bautista-Renedo, Nelly González-Rivas, Alejandro Dorazco-González. Chemosensing of Guanosine Triphosphate Based on a Fluorescent Dinuclear Zn(II)-Dipicolylamine Complex in Water. Inorganic chemistry. 2020 Jun; 59(11):7739-7751. doi: 10.1021/acs.inorgchem.0c00777. [PMID: 32391691]
  • Abdo A Elfiky. Anti-HCV, nucleotide inhibitors, repurposing against COVID-19. Life sciences. 2020 May; 248(?):117477. doi: 10.1016/j.lfs.2020.117477. [PMID: 32119961]
  • Takuma Kishimoto, Nario Tomishige, Motohide Murate, Reiko Ishitsuka, Hubert Schaller, Yves Mély, Kazumitsu Ueda, Toshihide Kobayashi. Cholesterol asymmetry at the tip of filopodia during cell adhesion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020 05; 34(5):6185-6197. doi: 10.1096/fj.201900065rr. [PMID: 32162745]
  • Honghong Sun, Mei Lin, Ali Zamani, Jason R Goldsmith, Amanda E Boggs, Mingyue Li, Chin-Nien Lee, Xu Chen, Xinyuan Li, Ting Li, Brigid L Dorrity, Ning Li, Yunwei Lou, Songlin Shi, Wei Wang, Youhai H Chen. The TIPE Molecular Pilot That Directs Lymphocyte Migration in Health and Inflammation. Scientific reports. 2020 04; 10(1):6617. doi: 10.1038/s41598-020-63629-w. [PMID: 32313148]
  • Linda Sistemich, Miriam Kutsch, Benjamin Hämisch, Ping Zhang, Sergii Shydlovskyi, Nathalie Britzen-Laurent, Michael Stürzl, Klaus Huber, Christian Herrmann. The Molecular Mechanism of Polymer Formation of Farnesylated Human Guanylate-binding Protein 1. Journal of molecular biology. 2020 03; 432(7):2164-2185. doi: 10.1016/j.jmb.2020.02.009. [PMID: 32087202]
  • Gang Li, Qian Zhao, Tian Luan, Yangbo Hu, Yueling Zhang, Ting Li, Chunlai Wang, Fang Xie, Wanjiang Zhang, Paul R Langford, Siguo Liu. Basal-Level Effects of (p)ppGpp in the Absence of Branched-Chain Amino Acids in Actinobacillus pleuropneumoniae. Journal of bacteriology. 2020 03; 202(8):. doi: 10.1128/jb.00640-19. [PMID: 32015147]
  • Karolina Luczkowska, Caroline Stekelenburg, Frédérique Sloan-Béna, Emmanuelle Ranza, Giacomo Gastaldi, Valérie Schwitzgebel, Pierre Maechler. Hyperinsulinism associated with GLUD1 mutation: allosteric regulation and functional characterization of p.G446V glutamate dehydrogenase. Human genomics. 2020 03; 14(1):9. doi: 10.1186/s40246-020-00262-8. [PMID: 32143698]
  • Yuxin Li, Ashley E Ross. Plasma-treated carbon-fiber microelectrodes for improved purine detection with fast-scan cyclic voltammetry. The Analyst. 2020 Feb; 145(3):805-815. doi: 10.1039/c9an01636h. [PMID: 31820742]
  • Yifan Ge, Xiaojun Shi, Sivakumar Boopathy, Julie McDonald, Adam W Smith, Luke H Chao. Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane. eLife. 2020 01; 9(?):. doi: 10.7554/elife.50973. [PMID: 31922487]
  • Liselot Dewachter, Babette Deckers, Ella Martin, Pauline Herpels, Sotirios Gkekas, Wim Versées, Natalie Verstraeten, Maarten Fauvart, Jan Michiels. GTP Binding is Necessary for the Activation of a Toxic Mutant Isoform of the Essential GTPase ObgE. International journal of molecular sciences. 2019 Dec; 21(1):. doi: 10.3390/ijms21010016. [PMID: 31861427]
  • Selma Yilmaz Dejgaard, John F Presley. Rab18 regulates lipolysis via Arf/GBF1 and adipose triglyceride lipase. Biochemical and biophysical research communications. 2019 12; 520(3):526-531. doi: 10.1016/j.bbrc.2019.10.069. [PMID: 31610914]
  • Sanchaita Das, Andrew W Malaby, Agata Nawrotek, Wenhua Zhang, Mahel Zeghouf, Sarah Maslen, Mark Skehel, Srinivas Chakravarthy, Thomas C Irving, Osman Bilsel, Jacqueline Cherfils, David G Lambright. Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes. Structure (London, England : 1993). 2019 12; 27(12):1782-1797.e7. doi: 10.1016/j.str.2019.09.007. [PMID: 31601460]
  • Sophia Karouzaki, Charoula Peta, Emmanouella Tsirimonaki, Dimitra Mangoura. PKCε-dependent H-Ras activation encompasses the recruitment of the RasGEF SOS1 and of the RasGAP neurofibromin in the lipid rafts of embryonic neurons. Neurochemistry international. 2019 12; 131(?):104582. doi: 10.1016/j.neuint.2019.104582. [PMID: 31629778]
  • Hong-Miao Xia, Jin Wang, Xiao-Jie Xie, Li-Juan Xu, Shi-Qi Tang. Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats. International journal of molecular medicine. 2019 Oct; 44(4):1523-1530. doi: 10.3892/ijmm.2019.4285. [PMID: 31364723]
  • Patrícia M Silva, Charles Puerner, Agnese Seminara, Martine Bassilana, Robert A Arkowitz. Secretory Vesicle Clustering in Fungal Filamentous Cells Does Not Require Directional Growth. Cell reports. 2019 08; 28(8):2231-2245.e5. doi: 10.1016/j.celrep.2019.07.062. [PMID: 31433995]
  • Peter Major, Kacper M Sendra, Paul Dean, Tom A Williams, Andrew K Watson, David T Thwaites, T Martin Embley, Robert P Hirt. A new family of cell surface located purine transporters in Microsporidia and related fungal endoparasites. eLife. 2019 07; 8(?):. doi: 10.7554/elife.47037. [PMID: 31355745]
  • Srikanth Budnar, Kabir B Husain, Guillermo A Gomez, Maedeh Naghibosadat, Amrita Varma, Suzie Verma, Nicholas A Hamilton, Richard G Morris, Alpha S Yap. Anillin Promotes Cell Contractility by Cyclic Resetting of RhoA Residence Kinetics. Developmental cell. 2019 06; 49(6):894-906.e12. doi: 10.1016/j.devcel.2019.04.031. [PMID: 31105010]
  • Yuta Homma, Riko Kinoshita, Yoshihiko Kuchitsu, Paulina S Wawro, Soujiro Marubashi, Mai E Oguchi, Morié Ishida, Naonobu Fujita, Mitsunori Fukuda. Comprehensive knockout analysis of the Rab family GTPases in epithelial cells. The Journal of cell biology. 2019 06; 218(6):2035-2050. doi: 10.1083/jcb.201810134. [PMID: 31072826]
  • Ileana Márquez, Gabriel Díaz-Haro, Marisela Vélez. Surface Orientation and Binding Strength Modulate Shape of FtsZ on Lipid Surfaces. International journal of molecular sciences. 2019 May; 20(10):. doi: 10.3390/ijms20102545. [PMID: 31137602]
  • Zhihua Wang, Unchol Kim, Yanting Jiao, Chaowen Li, Yingying Guo, Xiaoyao Ma, Min Jiang, Zhihong Jiang, Yuanyuan Hou, Gang Bai. Quantitative Proteomics Combined with Affinity MS Revealed the Molecular Mechanism of Ginsenoside Antitumor Effects. Journal of proteome research. 2019 05; 18(5):2100-2108. doi: 10.1021/acs.jproteome.8b00972. [PMID: 30860844]
  • Malgorzata M Kopacz, André S G Lorenzoni, Carlos R Polaquini, Luis O Regasini, Dirk-Jan Scheffers. Purification and characterization of FtsZ from the citrus canker pathogen Xanthomonas citri subsp. citri. MicrobiologyOpen. 2019 05; 8(5):e00706. doi: 10.1002/mbo3.706. [PMID: 30085414]
  • Ron Orbach, Jonathon Howard. The dynamic and structural properties of axonemal tubulins support the high length stability of cilia. Nature communications. 2019 04; 10(1):1838. doi: 10.1038/s41467-019-09779-6. [PMID: 31015426]
  • Y Liu, J-B Chen, M Zhang, X-L Zhang, J-L Meng, J Zhou, Z-Y Hao, L Zhang, X-B Zu, C-Z Liang. SGK2 promotes renal cancer progression via enhancing ERK 1/2 and AKT phosphorylation. European review for medical and pharmacological sciences. 2019 Apr; 23(7):2756-2767. doi: 10.26355/eurrev_201904_17549. [PMID: 31002126]
  • Lu Cheng, Xin Zhang, Xiaojie Zheng, Zufang Wu, Peifang Weng. RNA-seq transcriptomic analysis of green tea polyphenols regulation of differently expressed genes in Saccharomyces cerevisiae under ethanol stress. World journal of microbiology & biotechnology. 2019 Mar; 35(4):59. doi: 10.1007/s11274-019-2639-4. [PMID: 30915597]
  • Jelena Sikimic, Timothy S McMillen, Cita Bleile, Frank Dastvan, Ulrich Quast, Peter Krippeit-Drews, Gisela Drews, Joseph Bryan. ATP binding without hydrolysis switches sulfonylurea receptor 1 (SUR1) to outward-facing conformations that activate KATP channels. The Journal of biological chemistry. 2019 03; 294(10):3707-3719. doi: 10.1074/jbc.ra118.005236. [PMID: 30587573]
  • Basanta Kumar Das, Pragyan Roy, Ajaya Kumar Rout, Deepak Ranjan Sahoo, Soumya Prasad Panda, Sushmita Pattanaik, Budheswar Dehury, Bijay Kumar Behera, Sudhansu Sekhar Mishra. Molecular cloning, GTP recognition mechanism and tissue-specific expression profiling of myxovirus resistance (Mx) protein in Labeo rohita (Hamilton) after Poly I:C induction. Scientific reports. 2019 03; 9(1):3956. doi: 10.1038/s41598-019-40323-0. [PMID: 30850653]
  • Tuomo Ketomäki, Maria Vähätupa, Ulrike May, Toini Pemmari, Ella Ruikka, Jussi Hietamo, Pirkka Kaipiainen, Harlan Barker, Seppo Parkkila, Hannele Uusitalo-Järvinen, Tero A H Järvinen. R-Ras regulates vascular permeability, but not overall healing in skin wounds. Experimental dermatology. 2019 02; 28(2):202-206. doi: 10.1111/exd.13851. [PMID: 30489650]
  • Benjamin Auxier, Jaclyn Dee, Mary L Berbee, Michelle Momany. Diversity of opisthokont septin proteins reveals structural constraints and conserved motifs. BMC evolutionary biology. 2019 01; 19(1):4. doi: 10.1186/s12862-018-1297-8. [PMID: 30616529]
  • Tsai-Shin Chiang, Ming-Chieh Lin, Meng-Chen Tsai, Chieh-Hsin Chen, Li-Ting Jang, Fang-Jen S Lee. ADP-ribosylation factor-like 4A interacts with Robo1 to promote cell migration by regulating Cdc42 activation. Molecular biology of the cell. 2019 01; 30(1):69-81. doi: 10.1091/mbc.e18-01-0001. [PMID: 30427759]
  • Zhengxiao Zhao, Baojun Liu, Jing Sun, Linwei Lu, Lumei Liu, Jian Qiu, Qiuping Li, Chen Yan, Shan Jiang, Nabijan Mohammadtursun, Wenjuan Ma, Mihui Li, Jingcheng Dong, Weiyi Gong. Scutellaria Flavonoids Effectively Inhibit the Malignant Phenotypes of Non-small Cell Lung Cancer in an Id1-dependent Manner. International journal of biological sciences. 2019; 15(7):1500-1513. doi: 10.7150/ijbs.33146. [PMID: 31337979]
  • Ricardo Charles, Mohamed Bourmoum, Shirley Campbell, Audrey Claing. Methods to Investigate the β-Arrestin-Mediated Control of ARF6 Activation to Regulate Trafficking and Actin Cytoskeleton Remodeling. Methods in molecular biology (Clifton, N.J.). 2019; 1957(?):159-168. doi: 10.1007/978-1-4939-9158-7_10. [PMID: 30919353]
  • Tomohiro Shima, Manatsu Morikawa, Junichi Kaneshiro, Taketoshi Kambara, Shinji Kamimura, Toshiki Yagi, Hiroyuki Iwamoto, Sotaro Uemura, Hideki Shigematsu, Mikako Shirouzu, Taro Ichimura, Tomonobu M Watanabe, Ryo Nitta, Yasushi Okada, Nobutaka Hirokawa. Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport. The Journal of cell biology. 2018 12; 217(12):4164-4183. doi: 10.1083/jcb.201711178. [PMID: 30297389]
  • Miguel A Betancourt-Solis, Tanvi Desai, James A McNew. The atlastin membrane anchor forms an intramembrane hairpin that does not span the phospholipid bilayer. The Journal of biological chemistry. 2018 11; 293(48):18514-18524. doi: 10.1074/jbc.ra118.003812. [PMID: 30287684]
  • Seng Zhu, Shaarvari Bhat, Sylvie Syan, Yoshihiko Kuchitsu, Mitsunori Fukuda, Chiara Zurzolo. Rab11a-Rab8a cascade regulates the formation of tunneling nanotubes through vesicle recycling. Journal of cell science. 2018 10; 131(19):. doi: 10.1242/jcs.215889. [PMID: 30209134]
  • Kelsey N Maxwell, Yong Zhou, John F Hancock. Rac1 Nanoscale Organization on the Plasma Membrane Is Driven by Lipid Binding Specificity Encoded in the Membrane Anchor. Molecular and cellular biology. 2018 09; 38(18):. doi: 10.1128/mcb.00186-18. [PMID: 29967243]
  • Dan Dan Xu, Chong Bing Xu, Hon Ming Lam, Fuk-Ling Wong, Albert Wing Nang Leung, Merrin Man Long Leong, William Chi Shing Cho, Robin Hoeven, Qingtao Lv, Rong Rong. Proteomic analysis reveals that pheophorbide a-mediated photodynamic treatment inhibits prostate cancer growth by hampering GDP-GTP exchange of ras-family proteins. Photodiagnosis and photodynamic therapy. 2018 Sep; 23(?):35-39. doi: 10.1016/j.pdpdt.2018.05.014. [PMID: 29800714]
  • Lynn G L Richardson, Eliana L Small, Hitoshi Inoue, Danny J Schnell. Molecular Topology of the Transit Peptide during Chloroplast Protein Import. The Plant cell. 2018 Aug; 30(8):1789-1806. doi: 10.1105/tpc.18.00172. [PMID: 29991536]
  • Leopold Kong, Kem A Sochacki, Huaibin Wang, Shunming Fang, Bertram Canagarajah, Andrew D Kehr, William J Rice, Marie-Paule Strub, Justin W Taraska, Jenny E Hinshaw. Cryo-EM of the dynamin polymer assembled on lipid membrane. Nature. 2018 08; 560(7717):258-262. doi: 10.1038/s41586-018-0378-6. [PMID: 30069048]
  • Magdalena Blom, Katarina Reis, Pontus Aspenström. RhoD localization and function is dependent on its GTP/GDP-bound state and unique N-terminal motif. European journal of cell biology. 2018 Aug; 97(6):393-401. doi: 10.1016/j.ejcb.2018.05.003. [PMID: 29776664]
  • Marcin Krupka, Marta Sobrinos-Sanguino, Mercedes Jiménez, Germán Rivas, William Margolin. Escherichia coli ZipA Organizes FtsZ Polymers into Dynamic Ring-Like Protofilament Structures. mBio. 2018 06; 9(3):. doi: 10.1128/mbio.01008-18. [PMID: 29921670]
  • Guendalina Rossi, Kelly Watson, Wade Kennedy, Patrick Brennwald. The tomosyn homologue, Sro7, is a direct effector of the Rab GTPase, Sec4, in post-Golgi vesicle tethering. Molecular biology of the cell. 2018 06; 29(12):1476-1486. doi: 10.1091/mbc.e18-02-0138. [PMID: 29668350]