enoxacin (BioDeep_00001868182)
Main id: BioDeep_00000002432
代谢物信息卡片
enoxacin
化学式: C15H17FN4O3 (320.1284624)
中文名称: 依诺沙星
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O
InChI: InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23)
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01M - Quinolone antibacterials > J01MA - Fluoroquinolones
D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors > D065609 - Cytochrome P-450 CYP1A2 Inhibitors
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
同义名列表
1 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:157175
- KEGG: C06979
- KEGGdrug: D00310
- PubChem: 3229
- DrugBank: DB00467
- ChEMBL: CHEMBL826
- MeSH: Enoxacin
- CAS: 74011-58-8
- PubChem: 9193
- NIKKAJI: J20.568K
- RefMet: Enoxacin
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Nezar Boreak, Ethar Awad Alrajab, Rayan Ali Nahari, Loay Ebrahim Najmi, Muhannad Ali Masmali, Atiah Abdulrahman Ghawi, Mohammed M Al Moaleem, Majed Yahya Alhazmi, Abdulrahman Abdullah Maqbul. Unveiling Therapeutic Potential: Targeting Fusobacterium nucleatum's Lipopolysaccharide Biosynthesis for Endodontic Infections-An In Silico Screening Study.
International journal of molecular sciences.
2024 Apr; 25(8):. doi:
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Se pu = Chinese journal of chromatography.
2022 Sep; 40(9):843-853. doi:
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Journal of medicinal chemistry.
2022 08; 65(16):11010-11033. doi:
10.1021/acs.jmedchem.2c00189. [PMID: 35695407] - Zongyuan Zhou, Yiming Li, Xiaofang Ma, Biyun Cao, Ting Peng, Yuwen Sheng, Huipan Peng, Runze Li, Yu Cao, Ruiying Xi, Fu Li, Mengru Wang, Handong Sun, Guolin Zhang, Hongbin Zhang, Kaifeng Hu, Weilie Xiao, Fei Wang. Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Journal of medicinal chemistry.
2021 06; 64(11):7404-7421. doi:
10.1021/acs.jmedchem.1c00018. [PMID: 34038111] - Amirhossein Ahmadi, Sharif Moradi. In silico analysis suggests the RNAi-enhancing antibiotic enoxacin as a potential inhibitor of SARS-CoV-2 infection.
Scientific reports.
2021 05; 11(1):10271. doi:
10.1038/s41598-021-89605-6. [PMID: 33986351] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
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Viruses.
2020 12; 13(1):. doi:
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Viruses.
2020 09; 12(9):. doi:
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
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European journal of medicinal chemistry.
2019 Oct; 180(?):238-252. doi:
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European journal of medicinal chemistry.
2019 Sep; 178(?):726-739. doi:
10.1016/j.ejmech.2019.06.026. [PMID: 31229875] - Anna Margaret McDonnell, Holly M Pyles, Edgar S Diaz-Cruz, Christopher E Barton. Enoxacin and Epigallocatechin Gallate (EGCG) Act Synergistically to Inhibit the Growth of Cervical Cancer Cells in Culture.
Molecules (Basel, Switzerland).
2019 Apr; 24(8):. doi:
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Bioorganic & medicinal chemistry.
2019 03; 27(6):991-1001. doi:
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Carcinogenesis.
2019 03; 40(1):131-144. doi:
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Bioorganic & medicinal chemistry.
2018 12; 26(23-24):6115-6127. doi:
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European journal of medicinal chemistry.
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2012 May; 287(21):17894-17904. doi:
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2011 Jun; 11(?):7. doi:
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Antimicrobial agents and chemotherapy.
2010 Nov; 54(11):4765-71. doi:
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BMC nephrology.
2010 Aug; 11(?):19. doi:
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Journal of chromatographic science.
2010 Jan; 48(1):49-54. doi:
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Drug testing and analysis.
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2009 Dec; 28(12):2522-7. doi:
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2009 Jul; 19(3):107-11. doi:
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Drug and chemical toxicology.
2006 Jan; 29(1):25-38. doi:
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Guang pu xue yu guang pu fen xi = Guang pu.
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2005 Apr; 28(6):555-65. doi:
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The British journal of dermatology.
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The Japanese journal of antibiotics.
2002 Jun; 55(3):259-69. doi:
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