6-Oxoprostaglandin F1α (BioDeep_00001868172)
Main id: BioDeep_00000629487
代谢物信息卡片
6-keto-Prostaglandin F1alpha
化学式: C20H34O6 (370.2355)
中文名称: 6-酮-前列腺素F 1α
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCC(C=CC1C(CC(C1CC(=O)CCCCC(=O)O)O)O)O
InChI: InChI=1S/C20H34O6/c1-2-3-4-7-14(21)10-11-16-17(19(24)13-18(16)23)12-15(22)8-5-6-9-20(25)26/h10-11,14,16-19,21,23-24H,2-9,12-13H2,1H3,(H,25,26)/b11-10+/t14-,16+,17+,18+,19-/m0/s1
描述信息
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:28158
- KEGG: C05961
- PubChem: 5280888
- ChEMBL: CHEMBL2074840
- MeSH: 6-Ketoprostaglandin F1 alpha
- CAS: 58962-34-8
- PubChem: 8245
- LipidMAPS: LMFA03010001
- 3DMET: B01935
- NIKKAJI: J240.195I
- KNApSAcK: 28158
分类词条
相关代谢途径
Reactome(5)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yao Tang, Sunhua Huang, Wenhao Lin, Ke Wen, Zhexuan Lin, Ming Han. Arachidonic Acid-Dependent Pathway Inhibition in Platelets: its Role in Multiple Injury-Induced Coagulopathy and the Potential Mechanisms.
Shock (Augusta, Ga.).
2021 01; 55(1):121-127. doi:
10.1097/shk.0000000000001563. [PMID: 32433211] - Nicolai Rytter, Peter Piil, Howard Carter, Michael Nyberg, Ylva Hellsten, Lasse Gliemann. Microvascular Function Is Impaired after Short-Term Immobilization in Healthy Men.
Medicine and science in sports and exercise.
2020 10; 52(10):2107-2116. doi:
10.1249/mss.0000000000002369. [PMID: 32496738] - Sumith R Panicker, Indranil Biswas, Hemant Giri, Xiaofeng Cai, Alireza R Rezaie. PKC (Protein Kinase C)-δ Modulates AT (Antithrombin) Signaling in Vascular Endothelial Cells.
Arteriosclerosis, thrombosis, and vascular biology.
2020 07; 40(7):1748-1762. doi:
10.1161/atvbaha.120.314479. [PMID: 32404004] - Lili Li, Qi Huang, Xianchun Duan, Lan Han, Daiyin Peng. Protective effect of Clinopodium chinense (Benth.) O. Kuntze against abnormal uterine bleeding in female rats.
Journal of pharmacological sciences.
2020 May; 143(1):1-8. doi:
10.1016/j.jphs.2020.02.004. [PMID: 32094083] - Lasse Gliemann, Nicolai Rytter, Andrea Tamariz-Ellemann, Jon Egelund, Nina Brandt, Howard H Carter, Ylva Hellsten. Lifelong Physical Activity Determines Vascular Function in Late Postmenopausal Women.
Medicine and science in sports and exercise.
2020 03; 52(3):627-636. doi:
10.1249/mss.0000000000002180. [PMID: 31609299] - Changqin Li, Miyun Hu, Shengjun Jiang, Zhenhua Liang, Jinmei Wang, Zhenhua Liu, Hui-Min David Wang, Wenyi Kang. Evaluation Procoagulant Activity and Mechanism of Astragalin.
Molecules (Basel, Switzerland).
2020 Jan; 25(1):. doi:
10.3390/molecules25010177. [PMID: 31906332] - Chunpeng Lu, Yanping Yin, Yongliang Cui, Lili Wang, Yan Bai, Jian Li, Tingting Huang, Maimaiti Reziwanguli, Lifu Miao. 1,25(OH)2D3 improves blood lipid metabolism, liver function, and atherosclerosis by constraining the TGF-β/Smad signaling pathway in rats with hyperlipidemia.
Cell cycle (Georgetown, Tex.).
2019 Nov; 18(22):3111-3124. doi:
10.1080/15384101.2019.1669389. [PMID: 31544583] - Linea L Ring, Rune B Strandby, Amalie Henriksen, Rikard Ambrus, Henrik Sørensen, Jens P Gøtze, Lars B Svendsen, Michael P Achiam. Laser speckle contrast imaging for quantitative assessment of facial flushing during mesenteric traction syndrome in upper gastrointestinal surgery.
Journal of clinical monitoring and computing.
2019 Oct; 33(5):903-910. doi:
10.1007/s10877-018-0226-0. [PMID: 30460600] - Anindita A Nandi, Nisha S Wadhwani, Sadhana R Joshi. Maternal vitamin D deficiency increases the thromboxane/prostacyclin ratio through alterations in the one-carbon cycle in Wistar rats.
BioFactors (Oxford, England).
2019 Jul; 45(4):548-555. doi:
10.1002/biof.1510. [PMID: 30985971] - Chun-Cai Zou, Hai-Yan Yan, Li-Li Wang, Ying-Ying Bian. [Anti-platelet aggregation and anti-thrombotic mechanism of Trichosanthis Fructus combined with aspirin based on network pharmacology].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2019 Apr; 44(8):1654-1659. doi:
10.19540/j.cnki.cjcmm.20190111.003. [PMID: 31090331] - Yu He, Xiaohui Lou, Zhan Jin, Li Yu, Ling Deng, Haitong Wan. Mahuang decoction mitigates airway inflammation and regulates IL-21/STAT3 signaling pathway in rat asthma model.
Journal of ethnopharmacology.
2018 Oct; 224(?):373-380. doi:
10.1016/j.jep.2018.06.011. [PMID: 29906536] - Ran Ni, Nima Vaezzadeh, Ji Zhou, Jeffrey I Weitz, Marco Cattaneo, Peter L Gross. Effect of Different Doses of Acetylsalicylic Acid on the Antithrombotic Activity of Clopidogrel in a Mouse Arterial Thrombosis Model.
Arteriosclerosis, thrombosis, and vascular biology.
2018 10; 38(10):2338-2344. doi:
10.1161/atvbaha.118.311404. [PMID: 30354213] - Yezhe Cheng, Yanjie Chu, Xitong Su, Kexia Zhang, Yu Zhang, Zhenzhong Wang, Wei Xiao, Longshan Zhao, Xiaohui Chen. Pharmacokinetic-pharmacodynamic modeling to study the anti-dysmenorrhea effect of Guizhi Fuling capsule on primary dysmenorrhea rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2018 Sep; 48(?):141-151. doi:
10.1016/j.phymed.2018.04.041. [PMID: 30195872] - Kamil Przyborowski, Bartosz Proniewski, Joanna Czarny, Marta Smeda, Barbara Sitek, Agnieszka Zakrzewska, Jerzy A Zoladz, Stefan Chlopicki. Vascular Nitric Oxide-Superoxide Balance and Thrombus Formation after Acute Exercise.
Medicine and science in sports and exercise.
2018 07; 50(7):1405-1412. doi:
10.1249/mss.0000000000001589. [PMID: 29470281] - John M Thomason, Todd M Archer, Robert W Wills, Andrew J Mackin. Effects of immunosuppressive agents on the hemostatic system in normal dogs.
Journal of veterinary internal medicine.
2018 Jul; 32(4):1325-1333. doi:
10.1111/jvim.15132. [PMID: 29749651] - Jane A Mitchell, Rebecca B Knowles, Nicholas S Kirkby, Daniel M Reed, Matthew L Edin, William E White, Melissa V Chan, Hilary Longhurst, Magdi M Yaqoob, Ginger L Milne, Darryl C Zeldin, Timothy D Warner. Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M.
Circulation research.
2018 02; 122(4):555-559. doi:
10.1161/circresaha.117.312144. [PMID: 29298774] - N McLewee, T Archer, R Wills, A Mackin, J Thomason. Effects of aspirin dose escalation on platelet function and urinary thromboxane and prostacyclin levels in normal dogs.
Journal of veterinary pharmacology and therapeutics.
2018 Feb; 41(1):60-67. doi:
10.1111/jvp.12432. [PMID: 28664658] - Zu-Yue Deng, Wei-Guang Shan, Shen-Feng Wang, Meng-Mei Hu, Yan Chen. Effects of astaxanthin on blood coagulation, fibrinolysis and platelet aggregation in hyperlipidemic rats.
Pharmaceutical biology.
2017 Dec; 55(1):663-672. doi:
10.1080/13880209.2016.1261905. [PMID: 27951728] - K Przyborowski, H Kassassir, M Wojewoda, K Kmiecik, B Sitek, K Siewiera, A Zakrzewska, A M Rudolf, R Kostogrys, C Watala, J A Zoladz, S Chlopicki. Effects of a single bout of strenuous exercise on platelet activation in female ApoE/LDLR-/- mice.
Platelets.
2017 Nov; 28(7):657-667. doi:
10.1080/09537104.2016.1254764. [PMID: 28067100] - Tomiya Yasumasu, Kazuo Takahara, Yutaka Otsuji. Low-dose Aspirin Inhibits Cardiac Sympathetic Activation and Vagal Withdrawal Response to Morning Rising.
Journal of cardiovascular pharmacology.
2017 Oct; 70(4):239-244. doi:
10.1097/fjc.0000000000000509. [PMID: 28991105] - Gabriel Mayoral-Andrade, Laura Pérez-Campos-Mayoral, Abraham Majluf-Cruz, Eduardo Perez-Campos Mayoral, Carlos Perez Campos Mayoral, Ana Rocha-Núñez, Margarito Martinez, Edgar Zenteno, Leticia Hernandez-Gonzalez, María Guadalupe López Juan, Alma Dolores Pérez-Santiago, Eduardo Pérez-Campos. Reduced platelet aggregation in women after intercourse: a possible role for the cyclooxygenase pathway.
Clinical and experimental pharmacology & physiology.
2017 Aug; 44(8):847-853. doi:
10.1111/1440-1681.12783. [PMID: 28502103] - Pingyao Xie, Yong Zhang, Xuebiao Wang, Jinfeng Wei, Wenyi Kang. Antithrombotic effect and mechanism of Rubus spp. Blackberry.
Food & function.
2017 May; 8(5):2000-2012. doi:
10.1039/c6fo01717g. [PMID: 28485425] - Meryem Temiz-Resitoglu, Sefika Pinar Kucukkavruk, Demet Sinem Guden, Pelin Cecen, Ayse Nihal Sari, Bahar Tunctan, Aysegul Gorur, Lulufer Tamer-Gumus, Cuneyt Kemal Buharalioglu, Kafait U Malik, Seyhan Sahan-Firat. Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats.
European journal of pharmacology.
2017 May; 802(?):7-19. doi:
10.1016/j.ejphar.2017.02.034. [PMID: 28228357] - M Wojewoda, K Przyborowski, B Sitek, A Zakrzewska, L Mateuszuk, J A Zoladz, S Chlopicki. Effects of chronic nitric oxide synthase inhibition on V'O2max and exercise capacity in mice.
Naunyn-Schmiedeberg's archives of pharmacology.
2017 Mar; 390(3):235-244. doi:
10.1007/s00210-016-1318-3. [PMID: 27915453] - Junxiu Zhang, Yu Feng, Shaodan Li, Yi Liu, Yin Zhang, Yunxia Guo, Minghui Yang. Microvascular pathological features and changes in related injury factors in a rat acute blood stasis model.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2017 02; 37(1):108-15. doi:
10.1016/s0254-6272(17)30034-1. [PMID: 29957919] - Pingyao Xie, Lili Cui, Yuan Shan, Wen-Yi Kang. Antithrombotic Effect and Mechanism of Radix Paeoniae Rubra.
BioMed research international.
2017; 2017(?):9475074. doi:
10.1155/2017/9475074. [PMID: 28299338] - Opeyemi Abayomi Obilade, Alani Suleimon Akanmu, Fiona Broughton Pipkin, Bosede Bukola Afolabi. Prostacyclin, thromboxane and glomerular filtration rate are abnormal in sickle cell pregnancy.
PloS one.
2017; 12(9):e0184345. doi:
10.1371/journal.pone.0184345. [PMID: 28880908] - Hsin-Ling Ho, Shao-Jung Hsu, Fa-Yauh Lee, Hui-Chun Huang, I-Fang Hsin, Ming-Chih Hou, Shou-Dong Lee. Role of cyclooxygenase isoforms in encephalopathy of cirrhotic rats.
Journal of the Chinese Medical Association : JCMA.
2016 Nov; 79(11):583-588. doi:
10.1016/j.jcma.2016.05.007. [PMID: 27580512] - Giovanni Pallio, Alessandra Bitto, Gabriele Pizzino, Federica Galfo, Natasha Irrera, Letteria Minutoli, Vincenzo Arcoraci, Giovanni Squadrito, Antonio Macrì, Francesco Squadrito, Domenica Altavilla. Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.
European journal of pharmacology.
2016 Oct; 789(?):152-162. doi:
10.1016/j.ejphar.2016.07.033. [PMID: 27450484] - Andrzej Fedorowicz, Łukasz Mateuszuk, Grzegorz Kopec, Tomasz Skórka, Barbara Kutryb-Zając, Agnieszka Zakrzewska, Maria Walczak, Andrzej Jakubowski, Magdalena Łomnicka, Ewa Słomińska, Stefan Chlopicki. Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension.
Respiratory research.
2016 08; 17(1):108. doi:
10.1186/s12931-016-0423-7. [PMID: 27581040] - Jie Yin, Shuling You, Nannan Li, Shouhai Jiao, Hesheng Hu, Mei Xue, Ye Wang, Wenjuan Cheng, Ju Liu, Min Xu, Suhua Yan, Xiaolu Li. Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats.
Respiratory research.
2016 08; 17(1):99. doi:
10.1186/s12931-016-0409-5. [PMID: 27491388] - Yuan Cao, Jing Wang, Guozhu Su, Yan Wu, Ruifeng Bai, Qian Zhang, Xiaoli Gao, Chun Li, Suyile Chen, Pengfei Tu, Xingyun Chai. Anti-myocardial ischemia effect of Syringa pinnatifolia Hemsl. by inhibiting expression of cyclooxygenase-1 and -2 in myocardial tissues of mice.
Journal of ethnopharmacology.
2016 Jul; 187(?):259-68. doi:
10.1016/j.jep.2016.04.039. [PMID: 27130642] - Ning Ma, Xi-Wang Liu, Ya-Jun Yang, Dong-Shuai Shen, Xiao-Le Zhao, Isam Mohamed, Xiao-Jun Kong, Jian-Yong Li. Evaluation on antithrombotic effect of aspirin eugenol ester from the view of platelet aggregation, hemorheology, TXB2/6-keto-PGF1α and blood biochemistry in rat model.
BMC veterinary research.
2016 Jun; 12(1):108. doi:
10.1186/s12917-016-0738-0. [PMID: 27296110] - Ewelina Jursza-Piotrowska, Marta J Siemieniuch. Identifying diagnostic endocrine markers and changes in endometrial gene expressions during pyometra in cats.
Reproductive biology.
2016 Jun; 16(2):174-80. doi:
10.1016/j.repbio.2015.12.003. [PMID: 27288342] - Yu-yan Zhang, Hui-fen Zhou, Jie-hong Yang, Yu He, Xiao-qiang Chen, Katsuyoshi Nishinari, Hao-fang Wan, Hai-tong Wan. Effects of Danhong Injection (丹红注射液) and its main components on anticoagulation and fibrinolysis in cultured vein endothelial cells.
Chinese journal of integrative medicine.
2016 Apr; 22(4):276-83. doi:
10.1007/s11655-016-2498-x. [PMID: 27059485] - Filip Mejza, Aleksander Kania, Pawel Nastalek, Agata Nizankowska-Jedrzejczyk, Ewa Nizankowska-Mogilnicka. Systemic prostacyclin and thromboxane production in obstructive sleep apnea.
Advances in medical sciences.
2016 Mar; 61(1):154-9. doi:
10.1016/j.advms.2015.12.001. [PMID: 26773760] - Ferdous Khan, Pinky Karim Syeda, Michael Nii N Nartey, Mohammad Shahidur Rahman, Mohammad Safiqul Islam, Kohji Nishimura, Mitsuo Jisaka, Fumiaki Shono, Kazushige Yokota. Pretreatment of cultured preadipocytes with arachidonic acid during the differentiation phase without a cAMP-elevating agent enhances fat storage after the maturation phase.
Prostaglandins & other lipid mediators.
2016 03; 123(?):16-27. doi:
10.1016/j.prostaglandins.2016.02.003. [PMID: 26928048] - I N Medvedev. [Dynamics of violations of intravascular platelet activity in rats during the formation of metabolic syndrome using fructose models].
Voprosy pitaniia.
2016; 85(1):42-6. doi:
NULL. [PMID: 27228700] - Haruyo Ujike-Omori, Yohei Maeshima, Masaru Kinomura, Katsuyuki Tanabe, Kiyoshi Mori, Hiroyuki Watatani, Norikazu Hinamoto, Hitoshi Sugiyama, Yoshiki Sakai, Hiroshi Morimatsu, Hirofumi Makino. The urinary levels of prostanoid metabolites predict acute kidney injury in heterogeneous adult Japanese ICU patients: a prospective observational study.
Clinical and experimental nephrology.
2015 Dec; 19(6):1024-36. doi:
10.1007/s10157-015-1092-4. [PMID: 25669623] - Linli Wang, Yunru Yu, Jihong Yang, Xiaoping Zhao, Zheng Li. Dissecting Xuesaitong's mechanisms on preventing stroke based on the microarray and connectivity map.
Molecular bioSystems.
2015 Nov; 11(11):3033-9. doi:
10.1039/c5mb00379b. [PMID: 26305988] - Shuang-kun Wang, Chen Lu, You-jing Wang. [Effects of Electroacupuncture Stimulation of "Neiguan" (PC 6) at Different Frequencies on Plasma Vasoactive Substance Levels in Myocardial Ischemic Reperfusion Rats].
Zhen ci yan jiu = Acupuncture research.
2015 Oct; 40(5):378-82. doi:
. [PMID: 26669194] - Xuan Dang, Jing-Jing Miao, An-Qi Chen, Peng Li, Lin Chen, Jin-Ru Liang, Ren-Ming Xie, Ye Zhao. The antithrombotic effect of RSNK in blood-stasis model rats.
Journal of ethnopharmacology.
2015 Sep; 173(?):266-72. doi:
10.1016/j.jep.2015.06.030. [PMID: 26216512] - Jules I Schwartz, Bret J Musser, Wesley K Tanaka, William V Taggart, Anish Mehta, Keith M Gottesdiener, Howard E Greenberg. Inhibition of prostacyclin and thromboxane biosynthesis in healthy volunteers by single and multiple doses of acetaminophen and indomethacin.
Clinical pharmacology in drug development.
2015 09; 4(5):337-45. doi:
10.1002/cpdd.194. [PMID: 27137142] - Jianlu Wang, Lan Wang, Hongjun Yang, Yun You, Haiyu Xu, Leilei Gong, Xiaojie Yin, Wandan Wang, Shuangrong Gao, Long Cheng, Rixin Liang, Fulong Liao. Prevention of atherosclerosis by Yindan Xinnaotong capsule combined with swimming in rats.
BMC complementary and alternative medicine.
2015 Apr; 15(?):109. doi:
10.1186/s12906-015-0622-7. [PMID: 25886942] - Dimitrios Tsikas, Vu Vi Pham, Maria-Theresia Suchy, Marcel A van de Ree, Menno V Huisman, Jürgen C Frölich, Hans M G Princen. No effects of atorvastatin (10 mg/d or 80 mg/d) on nitric oxide, prostacyclin, thromboxane and oxidative stress in type 2 diabetes mellitus patients of the DALI study.
Pharmacological research.
2015 Apr; 94(?):1-8. doi:
10.1016/j.phrs.2015.01.004. [PMID: 25662039] - Dong Luo, Abul Fajol, Anja T Umbach, Angelika A Noegel, Stefan Laufer, Florian Lang, Michael Föller. Influence of annexin A7 on insulin sensitivity of cellular glucose uptake.
Pflugers Archiv : European journal of physiology.
2015 Apr; 467(4):641-9. doi:
10.1007/s00424-014-1541-z. [PMID: 24903239] - Elizabeth Alejandrina Guzmán-Hernández, Rafael Villalobos-Molina, María Alicia Sánchez-Mendoza, Leonardo Del Valle-Mondragón, Gustavo Pastelín-Hernández, Maximiliano Ibarra-Barajas. Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension.
Canadian journal of physiology and pharmacology.
2015 Apr; 93(4):299-308. doi:
10.1139/cjpp-2014-0347. [PMID: 25761067] - Yang Zhan, Hong Shi, Stephanie P B Caligiuri, Yinghong Wu, Vanessa Declercq, Carla G Taylor, Peter Zahradka, Malcolm R Ogborn, Harold M Aukema. Trans-10,cis-12-conjugated linoleic acid worsens renal pathology and alters cyclooxygenase derived oxylipins in obesity-associated nephropathy.
The Journal of nutritional biochemistry.
2015 Feb; 26(2):130-7. doi:
10.1016/j.jnutbio.2014.09.011. [PMID: 25458529] - Shaohong Yu, Shou wei Yue, Zhaochun Liu, Tiefeng Zhang, Nan Xiang, Hui Fu. Yerba mate (Ilex paraguariensis) improves microcirculation of volunteers with high blood viscosity: a randomized, double-blind, placebo-controlled trial.
Experimental gerontology.
2015 Feb; 62(?):14-22. doi:
10.1016/j.exger.2014.12.016. [PMID: 25562195] - Evi X Stavrou, Chao Fang, Alona Merkulova, Omar Alhalabi, Nadja Grobe, Silvio Antoniak, Nigel Mackman, Alvin H Schmaier. Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor.
Blood.
2015 Jan; 125(4):710-9. doi:
10.1182/blood-2014-01-550285. [PMID: 25339356] - Kamil Przyborowski, Marta Wojewoda, Barbara Sitek, Agnieszka Zakrzewska, Agnieszka Kij, Krystyna Wandzel, Jerzy Andrzej Zoladz, Stefan Chlopicki. Effects of 1-Methylnicotinamide (MNA) on Exercise Capacity and Endothelial Response in Diabetic Mice.
PloS one.
2015; 10(6):e0130908. doi:
10.1371/journal.pone.0130908. [PMID: 26115505] - Johan Rohde, Hans R Pedersen, Peter N Bjerring, Fin Stolze Larsen. Effects of dexamethasone and cox inhibitors on intracranial pressure and cerebral perfusion in the lipopolysaccharide treated rats with hyperammonemia.
PloS one.
2015; 10(2):e0117416. doi:
10.1371/journal.pone.0117416. [PMID: 25675251] - T Wang, l H Jiang, J B Zhu, X Y Wei, L Li, B Liu. Effect of hypertonic sodium chloride hydroxyethyl starch 40 on ET, TXB2, 6-keto-PGF1α, and ANP of preeclampsia in caesarean section.
Clinical and experimental obstetrics & gynecology.
2015; 42(1):36-9. doi:
. [PMID: 25864279] - Jeffrey S Zaltzman, Vesta Lai, Miklos Z Schulz, Kyung-Hee Moon, David Z Cherney. A randomized cross-over comparison of short-term exposure of once-daily extended release tacrolimus and twice-daily tacrolimus on renal function in healthy volunteers.
Transplant international : official journal of the European Society for Organ Transplantation.
2014 Dec; 27(12):1294-302. doi:
10.1111/tri.12435. [PMID: 25160518] - Stephanie Ross, John Eikelboom, Sonia S Anand, Niclas Eriksson, Hertzel C Gerstein, Shamir Mehta, Stuart J Connolly, Lynda Rose, Paul M Ridker, Lars Wallentin, Daniel I Chasman, Salim Yusuf, Guillaume Paré. Association of cyclooxygenase-2 genetic variant with cardiovascular disease.
European heart journal.
2014 Sep; 35(33):2242-8a. doi:
10.1093/eurheartj/ehu168. [PMID: 24796340] - Dezhao Liu, Pinjie Huang, Xiaoyun Li, Mian Ge, Gangjian Luo, Ziqing Hei. Using inflammatory and oxidative biomarkers in urine to predict early acute kidney injury in patients undergoing liver transplantation.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2014 Aug; 19(5):424-9. doi:
10.3109/1354750x.2014.924997. [PMID: 24888736] - De-Jun Liu, Wei Chen, Yan-Miao Huo, Wei Liu, Jun-Feng Zhang, Rong Hua, Yong-Wei Sun. Prostacyclin decreases splanchnic vascular contractility in cirrhotic rats.
Hepatobiliary & pancreatic diseases international : HBPD INT.
2014 Aug; 13(4):416-22. doi:
10.1016/s1499-3872(14)60270-8. [PMID: 25100127] - V Cavalca, B Rocca, I Squellerio, A Dragani, F Veglia, F Pagliaccia, B Porro, S S Barbieri, E Tremoli, C Patrono. In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia.
Thrombosis and haemostasis.
2014 Jul; 112(1):118-27. doi:
10.1160/th13-10-0844. [PMID: 24671522] - Wenting Zhou, Adil Abdurahman, Anwar Umar, Guldiyar Iskander, Elzira Abdusalam, Benedicte Berké, Bernard Bégaud, Nicholas Moore. Effects of Cydonia oblonga Miller extracts on blood hemostasis, coagulation and fibrinolysis in mice, and experimental thrombosis in rats.
Journal of ethnopharmacology.
2014 May; 154(1):163-9. doi:
10.1016/j.jep.2014.03.056. [PMID: 24704668] - H Q Zhai, J R Hhang, M C Gao, Y Liu, S F Zhang, X H Wang, F Y Meng, Y P Wang. Comparative study between Ephedra sinica Stapf and Fructus Schisandrae Chinensis on ET-1 and 6-keto-prostaglandin F1α in rats with idiopathic pulmonary fibrosis.
Genetics and molecular research : GMR.
2014 May; 13(2):3761-71. doi:
10.4238/2014.may.13.3. [PMID: 24854661] - Michael Nyberg, Kaare Seidelin, Thomas Rostgaard Andersen, Nickie Neumann Overby, Ylva Hellsten, Jens Bangsbo. Biomarkers of vascular function in premenopausal and recent postmenopausal women of similar age: effect of exercise training.
American journal of physiology. Regulatory, integrative and comparative physiology.
2014 Apr; 306(7):R510-7. doi:
10.1152/ajpregu.00539.2013. [PMID: 24477543] - Agata Niżankowska-Jędrzejczyk, Fernanda R Almeida, Alan A Lowe, Aleksander Kania, Paweł Nastałek, Filip Mejza, Jonathan H Foley, Ewa Niżankowska-Mogilnicka, Anetta Undas. Modulation of inflammatory and hemostatic markers in obstructive sleep apnea patients treated with mandibular advancement splints: a parallel, controlled trial.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.
2014 Mar; 10(3):255-62. doi:
10.5664/jcsm.3522. [PMID: 24634622] - Yonghyun Lee, Wooseong Kim, Sungchae Hong, Huijeong Park, Soohwan Yum, Jeong-Hyun Yoon, Yunjin Jung. Colon-targeted celecoxib ameliorates TNBS-induced rat colitis: a potential pharmacologic mechanism and therapeutic advantages.
European journal of pharmacology.
2014 Mar; 726(?):49-56. doi:
10.1016/j.ejphar.2014.01.011. [PMID: 24462351] - Anwar Umar, Wenting Zhou, Elzira Abdusalam, Arzigul Tursun, Nadira Reyim, Ibadet Tohti, Nicholas Moore. Effect of Ocimum basilicum L. on cyclo-oxygenase isoforms and prostaglandins involved in thrombosis.
Journal of ethnopharmacology.
2014 Feb; 152(1):151-5. doi:
10.1016/j.jep.2013.12.051. [PMID: 24412551] - Ming-Qiu Shan, Xing Chen, Juan Li, Bin Yu, An-Wei Ding. [Comparative study on effects of Rubiae Radix et Rhizoma and carbonized Rubiae Radix et Rhizoma on acute blood stasis rat model].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2014 Feb; 39(3):493-7. doi:
NULL. [PMID: 24946554] - Chen Yu, Dong Qi, Wei Lian, Qing-Zhong Li, Hong-Juan Li, Hua-Ying Fan. Effects of danshensu on platelet aggregation and thrombosis: in vivo arteriovenous shunt and venous thrombosis models in rats.
PloS one.
2014; 9(11):e110124. doi:
10.1371/journal.pone.0110124. [PMID: 25375124] - Yujing Sun, Xuesen Wen, Yu Zhao, Tao Shen, Zhihua Liu, Huifeng Gao, Shubing Qiu, Ying Chen. Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats.
Journal of ethnopharmacology.
2013 Nov; 150(2):514-20. doi:
10.1016/j.jep.2013.08.057. [PMID: 24041459] - Lu Bai, Lin Zhu, Wen-Fu Tang, Mei-Hua Wan, Wei Huang, Guang-Yuan Chen. [Effects of electro-acupuncture at Zusanli point on gastric and intestinal blood flow in rats with acute necrotizing pancreatitis].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.
2013 Nov; 44(6):982-6. doi:
. [PMID: 24490517] - Stephen A Brose, Mikhail Y Golovko. Eicosanoid post-mortem induction in kidney tissue is prevented by microwave irradiation.
Prostaglandins, leukotrienes, and essential fatty acids.
2013 Oct; 89(5):313-8. doi:
10.1016/j.plefa.2013.09.005. [PMID: 24113545] - Rendong Ren, Yosuke Azuma, Takao Ojima, Takashi Hashimoto, Masashi Mizuno, Yosuke Nishitani, Masaru Yoshida, Takeshi Azuma, Kazuki Kanazawa. Modulation of platelet aggregation-related eicosanoid production by dietary F-fucoidan from brown alga Laminaria japonica in human subjects.
The British journal of nutrition.
2013 Sep; 110(5):880-90. doi:
10.1017/s000711451200606x. [PMID: 23374164] - Harold M Aukema, Jing Lu, Faye Borthwick, Spencer D Proctor. Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome.
The British journal of nutrition.
2013 Jul; 110(1):11-9. doi:
10.1017/s0007114512004606. [PMID: 23151363] - Jianyong Zhang, Rixin Liang, Lan Wang, Renyi Yan, Rui Hou, Shuangrong Gao, Bin Yang. Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats.
Journal of ethnopharmacology.
2013 Jul; 148(2):563-9. doi:
10.1016/j.jep.2013.04.053. [PMID: 23685195] - M Jungner, C Lundblad, P Bentzer. Rosuvastatin in experimental brain trauma: improved capillary patency but no effect on edema or cerebral blood flow.
Microvascular research.
2013 Jul; 88(?):48-55. doi:
10.1016/j.mvr.2013.03.004. [PMID: 23538316] - T Sankari, S L Hoti, L K Das, V Govindaraj, P K Das. Effect of Diethylcarbamazine (DEC) on prostaglandin levels in Wuchereria bancrofti infected microfilaraemics.
Parasitology research.
2013 Jun; 112(6):2353-9. doi:
10.1007/s00436-013-3399-y. [PMID: 23525692] - Darren T Beck, Darren P Casey, Jeffrey S Martin, Blaze D Emerson, Randy W Braith. Exercise training improves endothelial function in young prehypertensives.
Experimental biology and medicine (Maywood, N.J.).
2013 Apr; 238(4):433-41. doi:
10.1177/1535370213477600. [PMID: 23760009] - Jie Xue, Ke-Ping Zhang, Lu-Jia Zhu, Mei-Lin Xie, Hong-Quan Zhang. Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats.
Chinese journal of integrative medicine.
2013 Feb; 19(2):137-42. doi:
10.1007/s11655-012-1209-5. [PMID: 23001461] - Xiangqian Kong, Hai Yuan, Xuejun Wu, Jingyong Zhang, Hua Zhou, Maohua Wang, Yang Liu, Xing Jin. High-mobility-group box protein 1A box reduces development of sodium laurate-induced thromboangiitis obliterans in rats.
Journal of vascular surgery.
2013 Jan; 57(1):194-204. doi:
10.1016/j.jvs.2012.06.083. [PMID: 23069071] - Hongli Gao, Zhaochun Liu, Xiaolan Qu, Ying Zhao. Effects of Yerba Mate tea (Ilex paraguariensis) on vascular endothelial function and liver lipoprotein receptor gene expression in hyperlipidemic rats.
Fitoterapia.
2013 Jan; 84(?):264-72. doi:
10.1016/j.fitote.2012.12.024. [PMID: 23266732] - Gang Wu, Qiang Xie, Lin Xu, Hong Jiang, Zhengrong Huang, Congxin Huang. Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia.
Chemical & pharmaceutical bulletin.
2013; 61(2):121-4. doi:
10.1248/cpb.c12-00462. [PMID: 23207681] - J Mo, B Bai, Y Li, J Deng, S Zhang, Y Chen, Y Zeng. Expression of interleukin-18 in a rat model of deep vein thrombosis.
The Journal of cardiovascular surgery.
2012 Oct; 53(5):625-30. doi:
NULL. [PMID: 22318348] - Chan Chen, Chang-xun Chen, Xi-min Wu, Rui Wang, Yi-ming Li. [Effects of extracts of Radix Scrophulariae on blood pressure in spontaneously hypertensive rats and the underlying mechanisms].
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2012 Sep; 10(9):1009-17. doi:
10.3736/jcim20120910. [PMID: 22979933] - Yohei Fujimoto, Yuki Nomura, Kumiko Hirakawa, Arisa Hotta, Ai Nakamoto, Noriko Yoshikawa, Naoko Ohira, Shigeki Tatekawa. Flurbiprofen axetil provides a prophylactic benefit against mesenteric traction syndrome associated with remifentanil infusion during laparotomy.
Journal of anesthesia.
2012 Aug; 26(4):490-5. doi:
10.1007/s00540-012-1368-8. [PMID: 22382665] - Ling Zhu, Fang Yang, Chun-Lan Jin, Liang-Xiao Ma, Ying-Ru Chen, Hong-Wen Yuan, Jiang Zhu. [Effect of electroacupuncture at different frequencies on serum estradiol and progesterone levels in late-stage pregnancy rats].
Zhen ci yan jiu = Acupuncture research.
2012 Aug; 37(4):281-5. doi:
NULL. [PMID: 23140048] - Mark Enzler, Stefan Schipp, Laurent B Nicolas, Jasper Dingemanse, Christoph Siethoff. Determination of 6-keto prostaglandin F1α and its metabolites in human plasma by LC-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2012 Jul; 901(?):67-71. doi:
10.1016/j.jchromb.2012.05.044. [PMID: 22762914] - Bin Liu, Wenhong Luo, Yingzhan Zhang, Hui Li, Jiling Zhang, Xue-Rui Tan, Yingbi Zhou. Concomitant activation of functionally opposing prostacyclin and thromboxane prostanoid receptors by cyclo-oxygenase-1-mediated prostacyclin synthesis in mouse arteries.
Experimental physiology.
2012 Jul; 97(7):895-904. doi:
10.1113/expphysiol.2011.063784. [PMID: 22447972] - Yonghyun Lee, Hyunjeong Kim, Wooseong Kim, Jeong-Hyun Yoon, Seong Hoon Jeong, Yunjin Jung. Colon-specific delivery of celecoxib is a potential strategy to improve toxicological and pharmacological properties of the selective Cox-2 inhibitor: implication in treatment of familiar adenomatous polyposis.
Journal of drug targeting.
2012 Jul; 20(6):524-34. doi:
10.3109/1061186x.2012.693498. [PMID: 22632102] - C Skarke, N Alamuddin, J A Lawson, L Cen, K J Propert, G A Fitzgerald. Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649.
Clinical pharmacology and therapeutics.
2012 Jun; 91(6):986-93. doi:
10.1038/clpt.2012.3. [PMID: 22278334] - Yan Zhao, Xin Yu, Li-Li Shi, Bai-Nian Chen, Shao-Hua Wang, Guan-Hua Du. [Effects of the effective components group of xiaoshuantongluo formula on rat acute blood stasis model].
Yao xue xue bao = Acta pharmaceutica Sinica.
2012 May; 47(5):604-8. doi:
NULL. [PMID: 22812003] - Abdukerem Kaiser, Yuan-Yuan Wei, Xiao Li, Dong Yan, Akber Aisa Haji, Kerram Parhat. [Effects of two different extracts of total saponins from Cicer arietinum on kidney of T2DM rats].
Yao xue xue bao = Acta pharmaceutica Sinica.
2012 Apr; 47(4):541-5. doi:
. [PMID: 22799041] - Wen-Liang Song, Jane Stubbe, Emanuela Ricciotti, Naji Alamuddin, Salam Ibrahim, Irene Crichton, Maxwell Prempeh, John A Lawson, Robert L Wilensky, Lars Melholt Rasmussen, Ellen Puré, Garret A FitzGerald. Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.
The Journal of clinical investigation.
2012 Apr; 122(4):1459-68. doi:
10.1172/jci59262. [PMID: 22406532] - J S Martin, D T Beck, J M Aranda, R W Braith. Enhanced external counterpulsation improves peripheral artery function and glucose tolerance in subjects with abnormal glucose tolerance.
Journal of applied physiology (Bethesda, Md. : 1985).
2012 Mar; 112(5):868-76. doi:
10.1152/japplphysiol.01336.2011. [PMID: 22194326] - Jia-Wei Wang, Jue-Min Gao, Yu-Jie Huang. [Effects of puerarin on the vascular active factor related to cerebral vasospasm after aneurysm subarachnoid hemorrhage].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2012 Feb; 32(2):164-7. doi:
. [PMID: 22574584] - Cheng-Bin Zhou, Jian Zhuang, Ji-Mei Chen, Xiao-Hua Zhang, Raphael C Lui. Decrease in inflammatory response does not prevent placental dysfunction after fetal cardiac bypass in goats.
The Journal of thoracic and cardiovascular surgery.
2012 Feb; 143(2):445-50. doi:
10.1016/j.jtcvs.2011.07.011. [PMID: 21821267] - Xing Wei, Zhan-Yi Wang, Jie-Yang Li, Ling Wan, Fu-Yuan He, Xiao-Peng Duan, Guang-Wei Zhong, Yao Jiang, Dong-Sheng Wang. [Study of dahuangzhechong pills on anti-arterial thrombosis with the orthogonal design].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2012 Jan; 35(1):106-11. doi:
NULL. [PMID: 22734422] - Ashraf Mohammad El-Badry, Jae-Hwi Jang, Ahmed Elsherbiny, Claudio Contaldo, Yinghua Tian, Dimitri A Raptis, Endre Laczko, Wolfgang Moritz, Rolf Graf, Pierre-Alain Clavien. Chemical composition of hepatic lipids mediates reperfusion injury of the macrosteatotic mouse liver through thromboxane A(2).
Journal of hepatology.
2011 Dec; 55(6):1291-9. doi:
10.1016/j.jhep.2011.04.019. [PMID: 21703192] - Derek L Chappell, Xiaoyao Xiao, Waldemar Radziszewski, Omar F Laterza. Development and validation of a LC/MS/MS method for 6-keto PGF1α, a metabolite of prostacyclin (PGI₂).
Journal of pharmaceutical and biomedical analysis.
2011 Nov; 56(3):600-3. doi:
10.1016/j.jpba.2011.06.019. [PMID: 21782371] - Chun-hua Li, Xiao-xuan Ren, Meng-wei Guo, Ya-fang Zhao, Bo Ji, Yu-qi Liu, Hong-wen Yuan, Jie-ping Xie, Lu-fen Zhang, Jiang Zhu. [Effect of electroacupuncture at different acupoints on plasma TXB2 and 6-keto-PGF(1alpha), contents in dysmenorrhea rats].
Zhen ci yan jiu = Acupuncture research.
2011 Oct; 36(5):347-52. doi:
. [PMID: 22073886] - Caoimhe M Lynch, Ruth O'Kelly, Bernard Stuart, Achim Treumann, Ronan Conroy, Carmen L Regan. The role of thromboxane A(2) in the pathogenesis of intrauterine growth restriction associated with maternal smoking in pregnancy.
Prostaglandins & other lipid mediators.
2011 Aug; 95(1-4):63-7. doi:
10.1016/j.prostaglandins.2011.06.007. [PMID: 21723954] - J P Wang, H X Xu, Y X Wu, Y J Ye, J L Ruan, C M Xiong, Y L Cai. Ent-16β,17-dihydroxy-kauran-19-oic acid, a kaurane diterpene acid from Siegesbeckia pubescens, presents antiplatelet and antithrombotic effects in rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2011 Jul; 18(10):873-8. doi:
10.1016/j.phymed.2011.01.024. [PMID: 21377851]
