Ticarcillin (BioDeep_00001868066)

Main id: BioDeep_00000001974

 


代谢物信息卡片


Ticarcillin

化学式: C15H16N2O6S2 (384.0449756)
中文名称: 替卡西林
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CSC=C3)C(=O)O)C(=O)O)C
InChI: InChI=1S/C15H16N2O6S2/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23)/t7-,8-,9+,12-/m1/s1

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01C - Beta-lactam antibacterials, penicillins > J01CA - Penicillins with extended spectrum
A penicillin compound having a 6beta-[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino side-group.
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

1 个代谢物同义名

Ticarcillin



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Moli Wang, Yanxia Gao, Xueli Liu, Jing Zhang, Qiang Wang, Junshan Chang, Lantong Zhang. Determination and pharmacokinetic analysis of ticarcillin disodium-clavulanate potassium for injection in rat plasma by UPLC-ESI-MS/MS. The Journal of international medical research. 2020 Dec; 48(12):300060520967822. doi: 10.1177/0300060520967822. [PMID: 33356736]
  • Caleb J P Economou, Jennifer Ordoñez, Steven C Wallis, Brent Richards, Brett McWhinney, Jeffrey Lipman, Jason A Roberts. Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit. International journal of antimicrobial agents. 2020 Sep; 56(3):106058. doi: 10.1016/j.ijantimicag.2020.106058. [PMID: 32590056]
  • Caleb J P Economou, Jiao Xie, Gregory Comadira, Brent Richards, Mandy Tallott, Steven C Wallis, Jenny Ordoñez, Jeffrey Lipman, Jason A Roberts. Population pharmacokinetics of ticarcillin in critically ill patients receiving extended daily diafiltration. International journal of antimicrobial agents. 2019 Sep; 54(3):351-355. doi: 10.1016/j.ijantimicag.2019.06.027. [PMID: 31279852]
  • Grazia Piizzi, David T Parker, Yunshan Peng, Markus Dobler, Anup Patnaik, Som Wattanasin, Eugene Liu, Francois Lenoir, Jill Nunez, John Kerrigan, David McKenney, Colin Osborne, Donghui Yu, Leanne Lanieri, Jade Bojkovic, JoAnn Dzink-Fox, Maria-Dawn Lilly, Elizabeth R Sprague, Yipin Lu, Hongming Wang, Srijan Ranjitkar, Lili Xie, Bing Wang, Meir Glick, Lawrence G Hamann, Ruben Tommasi, Xia Yang, Charles R Dean. Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC. Journal of medicinal chemistry. 2017 06; 60(12):5002-5014. doi: 10.1021/acs.jmedchem.7b00377. [PMID: 28549219]
  • P Usarek, K Dobrzaniecka, K Szymanek-Majchrzak, A Sawicka-Grzelak, A Mlynarczyk, M Durlik, M Ciszek, L Paczek, A Chmura, A Kwiatkowski, G Mlynarczyk. Drug Susceptibility Assessment in Stenotrophomonas Maltophilia Strains Isolated From the Blood of Organ Transplantation Recipients in a Warsaw Teaching Hospital During 2011 to 2014. Transplantation proceedings. 2016 Jun; 48(5):1411-3. doi: 10.1016/j.transproceed.2016.01.072. [PMID: 27496417]
  • Sophia Lionaki, Konstantinos Panagiotellis, Demetrios Moris, George Daikos, Mina Psyhogiou, Spiridon Vernadakis, Georgios Zavos, John N Boletis. Clostridium difficile infection among kidney transplant recipients: frequency, clinical presentation, and outcome. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 2015 Mar; 123(3):234-9. doi: 10.1111/apm.12348. [PMID: 25556694]
  • Micah E Stevens, Paula M Pijut. Agrobacterium-mediated genetic transformation and plant regeneration of the hardwood tree species Fraxinus profunda. Plant cell reports. 2014 Jun; 33(6):861-70. doi: 10.1007/s00299-014-1562-2. [PMID: 24493252]
  • A B Bennett, P A Martin, S A Gottlieb, M Govendir. In vitro susceptibilities of feline and canine Escherichia coli and Pseudomonas spp. isolates to ticarcillin and ticarcillin-clavulanic acid. Australian veterinary journal. 2013 May; 91(5):171-8. doi: 10.1111/avj.12044. [PMID: 23614511]
  • Aaron T Wolman, Michael R Gionfriddo, Gregory A Heindel, Paran Mukhija, Sarah Witkowski, Ajay Bommareddy, Adam L Vanwert. Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics. Drug metabolism and disposition: the biological fate of chemicals. 2013 Apr; 41(4):791-800. doi: 10.1124/dmd.112.049569. [PMID: 23344796]
  • Rachida Kermas, Abdelaziz Touati, Lucien Brasme, Elisabeth Le Magrex-Debar, Sadjia Mehrane, François-Xavier Weill, Christophe De Champs. Characterization of extended-spectrum beta-lactamase-producing Salmonella enterica serotype Brunei and Heidelberg at the Hussein Dey hospital in Algiers (Algeria). Foodborne pathogens and disease. 2012 Sep; 9(9):803-8. doi: 10.1089/fpd.2012.1159. [PMID: 22871227]
  • Ivone Vaz-Moreira, Olga C Nunes, Célia M Manaia. Diversity and antibiotic resistance in Pseudomonas spp. from drinking water. The Science of the total environment. 2012 Jun; 426(?):366-74. doi: 10.1016/j.scitotenv.2012.03.046. [PMID: 22521167]
  • Xiao-ling Liu, Dai-zhi Peng, Liang Xue, Wen-ting Shu, Xin Zhou, Jing Liu. [Analysis of resistance phenotype and homology of Klebsiella pneumoniae in burn patients]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. 2012 Apr; 28(2):96-100. doi: . [PMID: 22781319]
  • Vânia Figueira, Elizabete A Serra, Ivone Vaz-Moreira, Teresa R S Brandão, Célia M Manaia. Comparison of ubiquitous antibiotic-resistant Enterobacteriaceae populations isolated from wastewaters, surface waters and drinking waters. Journal of water and health. 2012 Mar; 10(1):1-10. doi: 10.2166/wh.2011.002. [PMID: 22361697]
  • Janak Kishore. Isolation, identification & characterization of Proteus penneri--a missed rare pathogen. The Indian journal of medical research. 2012 Mar; 135(?):341-5. doi: . [PMID: 22561620]
  • Shen Wan, Amanda M Johnson, Illimar Altosaar. Expression of nitrous oxide reductase from Pseudomonas stutzeri in transgenic tobacco roots using the root-specific rolD promoter from Agrobacterium rhizogenes. Ecology and evolution. 2012 Feb; 2(2):286-97. doi: 10.1002/ece3.74. [PMID: 22423324]
  • Erdal Erol, Stephan J Locke, Judy K Donahoe, Mary A Mackin, Craig N Carter. Beta-hemolytic Streptococcus spp. from horses: a retrospective study (2000-2010). Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 2012 Jan; 24(1):142-7. doi: 10.1177/1040638711434138. [PMID: 22362945]
  • Izabela Korona-Glowniak, Ewelina Grywalska, Beata Chudzik, Agnieszka Bojarska-Junak, Anna Malm, Jacek Rolinski. Upper respiratory tract colonization by gram-negative rods in patients with chronic lymphocytic leukemia: analysis of risk factors. TheScientificWorldJournal. 2012; 2012(?):617218. doi: 10.1100/2012/617218. [PMID: 22606052]
  • Consuelo Esteve, Elena Alcaide, María Dolores Blasco. Aeromonas hydrophila subsp. dhakensis isolated from feces, water and fish in Mediterranean Spain. Microbes and environments. 2012; 27(4):367-73. doi: 10.1264/jsme2.me12009. [PMID: 22472298]
  • S Hammami, I Boutiba-Ben Boubaker, R Ghozzi, M Saidani, S Amine, S Ben Redjeb. Nosocomial outbreak of imipenem-resistant Pseudomonas aeruginosa producing VIM-2 metallo-β-lactamase in a kidney transplantation unit. Diagnostic pathology. 2011 Oct; 6(?):106. doi: 10.1186/1746-1596-6-106. [PMID: 22035284]
  • Elpis Mantadakis, Aggelos Tsalkidis, Maria Panopoulou, Spyridon Pagkalis, Gregory Tripsianis, Mathew E Falagas, Mathew Falagas, Sophia Kartali-Ktenidou, Athanassios Chatzimichael. Antimicrobial susceptibility of pediatric uropathogens in Thrace, Greece. International urology and nephrology. 2011 Jun; 43(2):549-55. doi: 10.1007/s11255-010-9768-x. [PMID: 20524067]
  • Joanna Mokracka, Ryszard Koczura, Konrad Pawłowski, Adam Kaznowski. Resistance patterns and integron cassette arrays of Enterobacter cloacae complex strains of human origin. Journal of medical microbiology. 2011 Jun; 60(Pt 6):737-743. doi: 10.1099/jmm.0.027979-0. [PMID: 21330416]
  • Joanna Mokracka, Ryszard Koczura, Lucyna Jabłońska, Adam Kaznowski. Phylogenetic groups, virulence genes and quinolone resistance of integron-bearing Escherichia coli strains isolated from a wastewater treatment plant. Antonie van Leeuwenhoek. 2011 May; 99(4):817-24. doi: 10.1007/s10482-011-9555-4. [PMID: 21293926]
  • James E Dombrowski, James C Baldwin, Steve C Alderman, Ruth C Martin. Transformation of Epichloë typhina by electroporation of conidia. BMC research notes. 2011 Mar; 4(?):46. doi: 10.1186/1756-0500-4-46. [PMID: 21375770]
  • Iman K Behiry, Emad A Abada, Entsar A Ahmed, Rania S Labeeb. Enteropathogenic Escherichia coli associated with diarrhea in children in Cairo, Egypt. TheScientificWorldJournal. 2011; 11(?):2613-9. doi: 10.1100/2011/485381. [PMID: 22262949]
  • Perlinot Herindrainy, Frédérique Randrianirina, Rila Ratovoson, Elisoa Ratsima Hariniana, Yves Buisson, Nathalie Genel, Dominique Decré, Guillaume Arlet, Antoine Talarmin, Vincent Richard. Rectal carriage of extended-spectrum beta-lactamase-producing gram-negative bacilli in community settings in Madagascar. PloS one. 2011; 6(7):e22738. doi: 10.1371/journal.pone.0022738. [PMID: 21829498]
  • Eric Gomez, Martha Sanchez, Zonaira Gul, Carl Urban, Noriel Mariano, Robert H K Eng, David B Huang, Tom Chiang. Polymyxin Combination Therapy and the Use of Serum Bactericidal Titers in the Management of KPC-Producing Klebsiella pneumoniae Infections: A Report of 3 Cases. Case reports in medicine. 2011; 2011(?):659769. doi: 10.1155/2011/659769. [PMID: 22162703]
  • Brett C McWhinney, Steven C Wallis, Tara Hillister, Jason A Roberts, Jeffrey Lipman, Jacobus P J Ungerer. Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 Jul; 878(22):2039-43. doi: 10.1016/j.jchromb.2010.05.027. [PMID: 20561826]
  • Todisoa Andriatahina, Frédérique Randrianirina, Eliosa Ratsima Hariniana, Antoine Talarmin, Honoré Raobijaona, Yves Buisson, Vincent Richard. High prevalence of fecal carriage of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a pediatric unit in Madagascar. BMC infectious diseases. 2010 Jul; 10(?):204. doi: 10.1186/1471-2334-10-204. [PMID: 20624313]
  • Jeffery T Zobell, Krow Ampofo, Jared Cash, Kent Korgenski, Barbara A Chatfield. High dose intermittent ticarcillin-clavulanate administration in pediatric cystic fibrosis patients. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 2010 Jul; 9(4):280-3. doi: 10.1016/j.jcf.2010.04.003. [PMID: 20472513]
  • Mitesh H Patel, Grishma R Trivedi, Sachin M Patel, Mahendra M Vegad. Antibiotic susceptibility pattern in urinary isolates of gram negative bacilli with special reference to AmpC β-lactamase in a tertiary care hospital. Urology annals. 2010 Jan; 2(1):7-11. doi: 10.4103/0974-7796.62915. [PMID: 20842250]
  • Tomasz Bogiel, Agnieszka Mikucka, Tomasz Skalski, Eugenia Gospodarek. [Occurrence and susceptibility to antibiotics of carbapenem-resistant Pseudomonas aeruginosa strains between 1998 and 2009]. Medycyna doswiadczalna i mikrobiologia. 2010; 62(3):221-9. doi: . [PMID: 21114014]
  • Sara Romano, Fabien Aujoulat, Estelle Jumas-Bilak, Agnès Masnou, Jean-Luc Jeannot, Enevold Falsen, Hélène Marchandin, Corinne Teyssier. Multilocus sequence typing supports the hypothesis that Ochrobactrum anthropi displays a human-associated subpopulation. BMC microbiology. 2009 Dec; 9(?):267. doi: 10.1186/1471-2180-9-267. [PMID: 20021660]
  • Manthena V S Varma, Bo Feng, R Scott Obach, Matthew D Troutman, Jonathan Chupka, Howard R Miller, Ayman El-Kattan. Physicochemical determinants of human renal clearance. Journal of medicinal chemistry. 2009 Aug; 52(15):4844-52. doi: 10.1021/jm900403j. [PMID: 19445515]
  • Ningxia Du, Paula M Pijut. Agrobacterium-mediated transformation of Fraxinus pennsylvanica hypocotyls and plant regeneration. Plant cell reports. 2009 Jun; 28(6):915-23. doi: 10.1007/s00299-009-0697-z. [PMID: 19343350]
  • Judilee Marrow, Julia K Whittington, Mark Mitchell, Lois L Hoyer, Carol Maddox. Prevalence and antibiotic-resistance characteristics of Enterococcus spp. Isolated from free-living and captive raptors in Central Illinois. Journal of wildlife diseases. 2009 Apr; 45(2):302-13. doi: 10.7589/0090-3558-45.2.302. [PMID: 19395740]
  • Emilie Laroche, Barbara Pawlak, Thierry Berthe, David Skurnik, Fabienne Petit. Occurrence of antibiotic resistance and class 1, 2 and 3 integrons in Escherichia coli isolated from a densely populated estuary (Seine, France). FEMS microbiology ecology. 2009 Apr; 68(1):118-30. doi: 10.1111/j.1574-6941.2009.00655.x. [PMID: 19243438]
  • Ritu Aggarwal, Uma Chaudhary, Rama Sikka. Detection of Extended Spectrum β-lactamase Production Among Uropathogens. Journal of laboratory physicians. 2009 Jan; 1(1):7-10. doi: 10.4103/0974-2727.44423. [PMID: 21938241]
  • Pinar Onguru, Ayse Erbay, Hurrem Bodur, Gulseren Baran, Esragul Akinci, Neriman Balaban, Mustafa Aydin Cevik. Imipenem-resistant Pseudomonas aeruginosa: risk factors for nosocomial infections. Journal of Korean medical science. 2008 Dec; 23(6):982-7. doi: 10.3346/jkms.2008.23.6.982. [PMID: 19119440]
  • Veronika Steinbauerová, Pavel Neumann, Jirí Macas. Experimental evidence for splicing of intron-containing transcripts of plant LTR retrotransposon Ogre. Molecular genetics and genomics : MGG. 2008 Nov; 280(5):427-36. doi: 10.1007/s00438-008-0376-8. [PMID: 18762986]
  • Viren A Javiya, Somsuvra B Ghatak, Kamlesh R Patel, Jagruti A Patel. Antibiotic susceptibility patterns of Pseudomonas aeruginosa at a tertiary care hospital in Gujarat, India. Indian journal of pharmacology. 2008 Oct; 40(5):230-4. doi: 10.4103/0253-7613.44156. [PMID: 20040963]
  • H Ben Abdallah, S Noomen, A Ben Elhadj Khélifa, O Sahnoun, A Elargoubi, M Mastouri. [Susceptibility patterns of Pseudomonas aeruginosa strains isolated in the Monastir region, Tunisia]. Medecine et maladies infectieuses. 2008 Oct; 38(10):554-6. doi: 10.1016/j.medmal.2008.05.002. [PMID: 18814981]
  • R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1385-405. doi: 10.1124/dmd.108.020479. [PMID: 18426954]
  • Magdalena Stoczko, Jean-Marie Frère, Gian Maria Rossolini, Jean-Denis Docquier. Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. Antimicrobial agents and chemotherapy. 2008 Jul; 52(7):2473-9. doi: 10.1128/aac.01062-07. [PMID: 18443127]
  • Efstratios Apostolakis, Nikolaos Panagopoulos, Efstratios N Koletsis, James Crockett, Helen Stamou-Kouki, Efrosini Sourgiadaki, Kriton Filos, Dimitrios Dougenis. Influence of ultra-low dose Aprotinin on thoracic surgical operations: a prospective randomized trial. Journal of cardiothoracic surgery. 2008 Mar; 3(?):14. doi: 10.1186/1749-8090-3-14. [PMID: 18361800]
  • Gregory Kaler, David M Truong, Akash Khandelwal, Megha Nagle, Satish A Eraly, Peter W Swaan, Sanjay K Nigam. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. The Journal of biological chemistry. 2007 Aug; 282(33):23841-53. doi: 10.1074/jbc.m703467200. [PMID: 17553798]
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  • P D Lister, V M Gardner, C C Sanders. Clavulanate induces expression of the Pseudomonas aeruginosa AmpC cephalosporinase at physiologically relevant concentrations and antagonizes the antibacterial activity of ticarcillin. Antimicrobial agents and chemotherapy. 1999 Apr; 43(4):882-9. doi: 10.1128/aac.43.4.882. [PMID: 10103195]
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