mecamylamine (BioDeep_00001867896)

Main id: BioDeep_00000003466

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


methyl(2,3,3-trimethyltrinorbornan-2-yl)amine

化学式: C11H21N (167.1674)
中文名称: 异莰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1(C2CCC(C2)C1(C)NC)C
InChI: InChI=1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3

描述信息

C - Cardiovascular system > C02 - Antihypertensives > C02B - Antiadrenergic agents, ganglion-blocking > C02BB - Secondary and tertiary amines
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D005730 - Ganglionic Blockers
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents

同义名列表

4 个代谢物同义名

methyl(2,3,3-trimethyltrinorbornan-2-yl)amine; mecamylamine; Mecamylamine; Mecamylamine



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 BDNF, CA1, CA3, CHAT, POMC, SLC6A3, TH, VEGFA
Peripheral membrane protein 1 ACHE
Endoplasmic reticulum membrane 1 DRD1
Nucleus 6 ACHE, CHAT, DRD1, FOS, TH, VEGFA
cytosol 5 CA1, CA3, CHAT, FOS, TH
dendrite 4 BDNF, DRD2, HTR1A, TH
nucleoplasm 1 FOS
RNA polymerase II transcription regulator complex 1 FOS
Cell membrane 7 ACHE, DRD1, DRD2, HTR1A, OPRD1, SLC6A3, TNF
Cell projection, axon 2 SLC6A3, TH
Multi-pass membrane protein 6 CACNA1I, DRD1, DRD2, HTR1A, OPRD1, SLC6A3
Golgi apparatus membrane 1 DRD2
Synapse 4 ACHE, CHAT, DRD2, HTR1A
cell surface 4 ACHE, SLC6A3, TNF, VEGFA
glutamatergic synapse 2 DRD1, DRD2
Golgi apparatus 2 ACHE, VEGFA
Golgi membrane 1 DRD2
neuromuscular junction 1 ACHE
neuronal cell body 2 SLC6A3, TNF
presynaptic membrane 4 DRD1, DRD2, OPRD1, SLC6A3
smooth endoplasmic reticulum 1 TH
synaptic vesicle 2 BDNF, TH
acrosomal vesicle 1 DRD2
plasma membrane 10 ACHE, BCHE, CACNA1I, DRD1, DRD2, HTR1A, OPRD1, REN, SLC6A3, TNF
synaptic vesicle membrane 2 DRD2, OPRD1
terminal bouton 1 TH
Membrane 7 ACHE, BDNF, CACNA1I, OPRD1, REN, SLC6A3, VEGFA
axon 4 BDNF, DRD2, SLC6A3, TH
extracellular exosome 1 CA1
endoplasmic reticulum 2 FOS, VEGFA
extracellular space 9 ACHE, BCHE, BDNF, IL10, IL6, POMC, REN, TNF, VEGFA
perinuclear region of cytoplasm 3 ACHE, BDNF, TH
adherens junction 1 VEGFA
mitochondrion 1 TH
Secreted 8 ACHE, BCHE, BDNF, IL10, IL6, POMC, REN, VEGFA
extracellular region 9 ACHE, BCHE, BDNF, IL10, IL6, POMC, REN, TNF, VEGFA
cytoplasmic side of plasma membrane 1 TH
neuronal cell body membrane 1 SLC6A3
Extracellular side 1 ACHE
ciliary membrane 2 DRD1, DRD2
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
dendritic spine 2 DRD1, DRD2
perikaryon 2 DRD2, TH
cytoplasmic vesicle 1 TH
Melanosome membrane 1 TH
apical part of cell 1 REN
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 3 DRD1, DRD2, SLC6A3
Cytoplasm, perinuclear region 1 TH
Membrane raft 2 SLC6A3, TNF
GABA-ergic synapse 2 DRD1, DRD2
flotillin complex 1 SLC6A3
extracellular matrix 1 VEGFA
basement membrane 1 ACHE
Cell projection, dendritic spine 1 DRD1
secretory granule 2 POMC, VEGFA
lateral plasma membrane 1 DRD2
Cell projection, neuron projection 1 SLC6A3
neuron projection 4 CHAT, OPRD1, SLC6A3, TH
cilium 2 DRD1, DRD2
chromatin 1 FOS
phagocytic cup 1 TNF
blood microparticle 1 BCHE
non-motile cilium 2 DRD1, DRD2
Lipid-anchor, GPI-anchor 1 ACHE
sperm flagellum 1 DRD2
Cell projection, dendrite 2 DRD1, HTR1A
side of membrane 1 ACHE
secretory granule lumen 1 POMC
endoplasmic reticulum lumen 3 BCHE, BDNF, IL6
nuclear matrix 1 FOS
platelet alpha granule lumen 1 VEGFA
axon terminus 3 DRD2, OPRD1, SLC6A3
voltage-gated calcium channel complex 1 CACNA1I
endocytic vesicle 1 DRD2
postsynaptic density membrane 1 OPRD1
neuronal dense core vesicle 1 OPRD1
nuclear envelope lumen 1 BCHE
synaptic cleft 1 ACHE
protein-DNA complex 1 FOS
dopaminergic synapse 2 DRD2, SLC6A3
dendrite membrane 1 OPRD1
Cell projection, cilium membrane 1 DRD1
transcription factor AP-1 complex 1 FOS
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
interleukin-6 receptor complex 1 IL6
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
G protein-coupled receptor complex 2 DRD1, DRD2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Isoform H]: Cell membrane 1 ACHE
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
spine apparatus 1 OPRD1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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