bithionol (BioDeep_00001867789)

Main id: BioDeep_00000006641

 

Volatile Flavor Compounds


代谢物信息卡片


bithionol

化学式: C12H6Cl4O2S (353.88426160000006)
中文名称: 硫双二氯酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(C=C(C(=C1SC2=C(C(=CC(=C2)Cl)Cl)O)O)Cl)Cl
InChI: InChI=1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H

描述信息

D - Dermatologicals > D10 - Anti-acne preparations > D10A - Anti-acne preparations for topical use > D10AB - Preparations containing sulfur
P - Antiparasitic products, insecticides and repellents > P02 - Anthelmintics > P02B - Antitrematodals
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent

同义名列表

2 个代谢物同义名

bithionol; Bithionol



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Karl Kevala, Michel Lagarde, Arthur A Spector, Hee-Yong Kim. Biosynthesis of N-Docosahexanoylethanolamine from Unesterified Docosahexaenoic Acid and Docosahexaenoyl-Lysophosphatidylcholine in Neuronal Cells. International journal of molecular sciences. 2020 Nov; 21(22):. doi: 10.3390/ijms21228768. [PMID: 33233525]
  • Geetika Aggarwal, Jonah E Zarrow, Zahra Mashhadi, C Robb Flynn, Paige Vinson, C David Weaver, Sean S Davies. Symmetrically substituted dichlorophenes inhibit N-acyl-phosphatidylethanolamine phospholipase D. The Journal of biological chemistry. 2020 05; 295(21):7289-7300. doi: 10.1074/jbc.ra120.013362. [PMID: 32284327]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Wooseong Kim, Guijin Zou, Taylor P A Hari, Ingrid K Wilt, Wenpeng Zhu, Nicolas Galle, Hammad A Faizi, Gabriel L Hendricks, Katerina Tori, Wen Pan, Xiaowen Huang, Andrew D Steele, Erika E Csatary, Madeline M Dekarske, Jake L Rosen, Noelly de Queiroz Ribeiro, Kiho Lee, Jenna Port, Beth Burgwyn Fuchs, Petia M Vlahovska, William M Wuest, Huajian Gao, Frederick M Ausubel, Eleftherios Mylonakis. A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 2019 08; 116(33):16529-16534. doi: 10.1073/pnas.1904700116. [PMID: 31358625]
  • Emil Jakobsen, Sofie C Lange, Jens V Andersen, Claus Desler, Henriette F Kihl, Michaela C Hohnholt, Malin H Stridh, Lene J Rasmussen, Helle S Waagepetersen, Lasse K Bak. The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms. Biochemical pharmacology. 2018 09; 155(?):92-101. doi: 10.1016/j.bcp.2018.06.023. [PMID: 29940175]
  • Matthew R Fleming, Maile R Brown, Jack Kronengold, Yalan Zhang, David P Jenkins, Gulia Barcia, Rima Nabbout, Anne E Bausch, Peter Ruth, Robert Lukowski, Dhasakumar S Navaratnam, Leonard K Kaczmarek. Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex. Cell reports. 2016 08; 16(9):2281-8. doi: 10.1016/j.celrep.2016.07.024. [PMID: 27545877]
  • Kana Matsubara, Seigo Sanoh, Shigeru Ohta, Shigeyuki Kitamura, Kazumi Sugihara, Nariaki Fujimoto. An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide. Toxicology letters. 2012 Jan; 208(1):30-5. doi: 10.1016/j.toxlet.2011.10.004. [PMID: 22015988]
  • Shao-Hua Long, Zhu-Qin Yu, Li Shuai, Yun-Liang Guo, De-Lin Duan, Xin-Ying Xu, Xiao-Dan Li. The hypoglycemic effect of the kelp on diabetes mellitus model induced by alloxan in rats. International journal of molecular sciences. 2012; 13(3):3354-65. doi: 10.3390/ijms13033354. [PMID: 22489155]
  • Jennifer Keiser, Hanan Sayed, Maged el-Ghanam, Hoda Sabry, Saad Anani, Aly el-Wakeel, Christoph Hatz, Jürg Utzinger, Sayed Seif el-Din, Walaa el-Maadawy, Sanaa Botros. Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials. PLoS neglected tropical diseases. 2011 Sep; 5(9):e1285. doi: 10.1371/journal.pntd.0001285. [PMID: 21909440]
  • Yasuto Kido, Pär Matsson, Kathleen M Giacomini. Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. Journal of medicinal chemistry. 2011 Jul; 54(13):4548-58. doi: 10.1021/jm2001629. [PMID: 21599003]
  • Frank C Victor, David E Cohen, Nicholas A Soter. A 20-year analysis of previous and emerging allergens that elicit photoallergic contact dermatitis. Journal of the American Academy of Dermatology. 2010 Apr; 62(4):605-10. doi: 10.1016/j.jaad.2009.06.084. [PMID: 20163891]
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  • Saki Takahashi, Yoichi Sakakibara, Emi Mishiro, Haruna Kouriki, Rika Nobe, Katsuhisa Kurogi, Shin Yasuda, Ming-Cheh Liu, Masahito Suiko. Molecular cloning, expression and characterization of a novel mouse SULT6 cytosolic sulfotransferase. Journal of biochemistry. 2009 Sep; 146(3):399-405. doi: 10.1093/jb/mvp087. [PMID: 19505954]
  • Ming Li, Christopher J Smith, Matthew T Walker, Thomas J Smith. Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. The Journal of biological chemistry. 2009 Aug; 284(34):22988-3000. doi: 10.1074/jbc.m109.020222. [PMID: 19531491]
  • Yoshinori Sanada, Hiroyuki Senba, Rieko Mochizuki, Hidemi Arakaki, Tadahiro Gotoh, Shin-Ichiro Fukumoto, Hajime Nagahata. Evaluation of marked rise in fecal egg output after bithionol administration to horse and its application as a diagnostic marker for equine Anoplocephala perfoliata infection. The Journal of veterinary medical science. 2009 May; 71(5):617-20. doi: 10.1292/jvms.71.617. [PMID: 19498288]
  • Judd L Walson, Grace John-Stewart. Treatment of helminth co-infection in individuals with HIV-1: A systematic review of the literature. PLoS neglected tropical diseases. 2007 Dec; 1(3):e102. doi: 10.1371/journal.pntd.0000102. [PMID: 18160978]
  • Renee L Florent, Joy A Becker, Mark D Powell. Evaluation of bithionol as a bath treatment for amoebic gill disease caused by Neoparamoeba spp. Veterinary parasitology. 2007 Mar; 144(3-4):197-207. doi: 10.1016/j.vetpar.2006.10.018. [PMID: 17129675]
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