D-Ribulose 5-phosphate (BioDeep_00000001741)

 

Secondary id: BioDeep_00001868493

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite


代谢物信息卡片


{[(2R,3R)-2,3,5-trihydroxy-4-oxopentyl]oxy}phosphonic acid

化学式: C5H11O8P (230.0192)
中文名称: D-核酮糖-5-磷酸
谱图信息: 最多检出来源 Homo sapiens(blood) 41.4%

Reviewed

Last reviewed on 2024-09-14.

Cite this Page

D-Ribulose 5-phosphate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/d-ribulose_5-phosphate (retrieved 2024-12-26) (BioDeep RN: BioDeep_00000001741). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(C(=O)[C@@H]([C@@H](COP(=O)(O)O)O)O)O
InChI: InChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h4-6,8-9H,1-2H2,(H2,10,11,12)/t4-,5+/m1/s1

描述信息

D-Ribulose 5-phosphate is a metabolite in the Pentose phosphate pathway, Pentose and glucuronate interconversions, and in the Riboflavin metabolism (KEGG) [HMDB]. D-Ribulose 5-phosphate is found in many foods, some of which are olive, cocoa bean, common chokecherry, and orange mint.
D-Ribulose 5-phosphate is a metabolite in the following pathways: pentose phosphate pathway, pentose and glucuronate interconversions, and riboflavin metabolism (KEGG).
Acquisition and generation of the data is financially supported in part by CREST/JST.

同义名列表

11 个代谢物同义名

{[(2R,3R)-2,3,5-trihydroxy-4-oxopentyl]oxy}phosphonic acid; D-Erythro-pent-2-ulose 5-(dihydrogen phosphoric acid); D-Erythro-pent-2-ulose 5-(dihydrogen phosphate); Ribulose 5-phosphate, (D)-isomer; Ribulose 5-phosphate, (L)-isomer; D-Ribulose 5-phosphoric acid; D-Ribulose 5-phosphate; D-Ribulose-5-phosphate; Ribulose 5-phosphate; Ru-5-P; Ara



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(4)

PlantCyc(0)

代谢反应

319 个相关的代谢反应过程信息。

Reactome(9)

BioCyc(23)

WikiPathways(2)

Plant Reactome(243)

INOH(2)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(40)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AKR1B1, CBS, FTO, G6PD, GAPDH, GPI, HPS1, PKM, RPIA, TXN
Peripheral membrane protein 4 G6PD, HK1, HK2, HSD17B6
Endoplasmic reticulum membrane 2 CYP1A2, TKT
Nucleus 5 CBS, FTO, GAPDH, PKM, TXN
cytosol 17 AKR1B1, CBS, FTO, G6PD, GAPDH, GLS, GPI, HK1, HK2, HPS1, PKM, RPE, RPIA, SLC2A1, TKT, TXN, XYLB
nuclear body 1 TKT
centrosome 1 HK2
nucleoplasm 5 AKR1B1, ATP2B1, FTO, TKT, TXN
Cell membrane 3 ATP2B1, SLC2A1, TKT
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 2 ATP2B1, SLC2A1
Synapse 2 ATP2B1, GLS
glutamatergic synapse 1 ATP2B1
Golgi membrane 1 SLC2A1
presynaptic membrane 1 ATP2B1
sarcolemma 1 SLC2A1
Cytoplasm, cytosol 5 G6PD, GAPDH, GLS, HK1, HK2
Lysosome 1 HPS1
Presynapse 1 SLC2A1
plasma membrane 5 ATP2B1, FTO, GAPDH, SLC2A1, TKT
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ATP2B1, G6PD, GAPDH, GPI, HK2, RPIA, SLC2A1
apical plasma membrane 2 SLC2A1, TKT
basolateral plasma membrane 2 ATP2B1, SLC2A1
caveola 1 SLC2A1
extracellular exosome 10 AKR1B1, ATP2B1, G6PD, GAPDH, GPI, PKM, RPE, SLC2A1, TKT, TXN
Lumenal side 1 HSD17B6
endoplasmic reticulum 1 HSD17B6
extracellular space 2 AKR1B1, GPI
perinuclear region of cytoplasm 1 GAPDH
intercalated disc 1 SLC2A1
mitochondrion 6 AKR1B1, GLS, HK1, HK2, PKM, RPIA
intracellular membrane-bounded organelle 7 ATP2B1, CYP1A2, FTO, G6PD, GAPDH, HK2, HSD17B6
Microsome membrane 2 CYP1A2, HSD17B6
Single-pass type I membrane protein 1 TKT
Secreted 3 GPI, HK2, TXN
extracellular region 3 GPI, PKM, TXN
cytoplasmic side of plasma membrane 1 G6PD
Mitochondrion outer membrane 2 HK1, HK2
mitochondrial outer membrane 2 HK1, HK2
mitochondrial matrix 1 GLS
centriolar satellite 1 G6PD
ciliary membrane 1 GPI
photoreceptor inner segment 1 SLC2A1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 GAPDH
Extracellular vesicle 1 PKM
actin cytoskeleton 1 TKT
Z disc 1 SLC2A1
cytoplasmic vesicle 1 HPS1
microtubule cytoskeleton 1 GAPDH
midbody 1 SLC2A1
vesicle 3 GAPDH, PKM, TKT
Cytoplasm, perinuclear region 1 GAPDH
Membrane raft 1 HK1
Cytoplasm, cytoskeleton 1 GAPDH
focal adhesion 1 TKT
Peroxisome 1 TKT
sarcoplasmic reticulum 1 HK2
collagen-containing extracellular matrix 1 PKM
lateral plasma membrane 1 ATP2B1
nuclear speck 1 FTO
receptor complex 1 TKT
cilium 1 PKM
cell projection 1 ATP2B1
cytoskeleton 1 GAPDH
[Isoform 1]: Mitochondrion 1 GLS
blood microparticle 1 SLC2A1
Basolateral cell membrane 1 ATP2B1
Lipid droplet 1 GAPDH
female germ cell nucleus 1 SLC2A1
Melanosome 1 SLC2A1
Nucleus speckle 1 FTO
Presynaptic cell membrane 1 ATP2B1
ficolin-1-rich granule lumen 2 GPI, PKM
secretory granule lumen 2 GPI, PKM
cortical actin cytoskeleton 1 SLC2A1
immunological synapse 1 ATP2B1
ribonucleoprotein complex 1 GAPDH
female pronucleus 1 SLC2A1
Rough endoplasmic reticulum 1 PKM
[Isoform 3]: Mitochondrion 1 GLS
GAIT complex 1 GAPDH
[Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix 1 GLS
[Glutaminase kidney isoform, mitochondrial 65 kDa chain]: Mitochondrion matrix 1 GLS
photoreceptor ribbon synapse 1 ATP2B1
glucose transporter complex 1 SLC2A1
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
BLOC-3 complex 1 HPS1


文献列表

  • Shama Afroz, Kahkashan Khatoon, Zafar Warsi, Zakir Husain, Sanjeet Kumar Verma, Laiq Ur Rahman. Molecular cloning and heterologous expression analysis of 1-Deoxy-D-Xylulose-5-Phosphate Synthase gene in Centella asiatica L. Gene. 2024 Feb; 895(?):148015. doi: 10.1016/j.gene.2023.148015. [PMID: 37984537]
  • Xueni Di, David Ortega-Alarcon, Ramu Kakumanu, Javier Iglesias-Fernandez, Lucia Diaz, Edward E K Baidoo, Adrian Velazquez-Campoy, Manuel Rodríguez-Concepción, Jordi Perez-Gil. MEP pathway products allosterically promote monomerization of deoxy-D-xylulose-5-phosphate synthase to feedback-regulate their supply. Plant communications. 2022 Dec; ?(?):100512. doi: 10.1016/j.xplc.2022.100512. [PMID: 36575800]
  • Roman G Fedunov, Victor A Sokolov. Possible Steps of the Carboxylation of Ribulose-1,5-biphosphate from Intermediates: 2,3-Enediol versus 1,2-Enol. International journal of molecular sciences. 2021 Sep; 22(18):. doi: 10.3390/ijms22189749. [PMID: 34575912]
  • Marie-Christin Baune, Hannes Lansing, Kerstin Fischer, Tanja Meyer, Lennart Charton, Nicole Linka, Antje von Schaewen. The Arabidopsis Plastidial Glucose-6-Phosphate Transporter GPT1 is Dually Targeted to Peroxisomes via the Endoplasmic Reticulum. The Plant cell. 2020 05; 32(5):1703-1726. doi: 10.1105/tpc.19.00959. [PMID: 32111666]
  • Vasilios M E Andriotis, Alison M Smith. The plastidial pentose phosphate pathway is essential for postglobular embryo development in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America. 2019 07; 116(30):15297-15306. doi: 10.1073/pnas.1908556116. [PMID: 31296566]
  • Thomas D Sharkey. Discovery of the canonical Calvin-Benson cycle. Photosynthesis research. 2019 May; 140(2):235-252. doi: 10.1007/s11120-018-0600-2. [PMID: 30374727]
  • Hai He, Christian Edlich-Muth, Steffen N Lindner, Arren Bar-Even. Ribulose Monophosphate Shunt Provides Nearly All Biomass and Energy Required for Growth of E. coli. ACS synthetic biology. 2018 06; 7(6):1601-1611. doi: 10.1021/acssynbio.8b00093. [PMID: 29756766]
  • Francesca Rizzello, Angelo De Paolis, Miriana Durante, Federica Blando, Giovanni Mita, Sofia Caretto. Enhanced production of bioactive isoprenoid compounds from cell suspension cultures of Artemisia annua L. using β-cyclodextrins. International journal of molecular sciences. 2014 Oct; 15(10):19092-105. doi: 10.3390/ijms151019092. [PMID: 25338048]
  • Liguo Feng, Chen Chen, Tinglin Li, Meng Wang, Jun Tao, Daqiu Zhao, Lixia Sheng. Flowery odor formation revealed by differential expression of monoterpene biosynthetic genes and monoterpene accumulation in rose (Rosa rugosa Thunb.). Plant physiology and biochemistry : PPB. 2014 Feb; 75(?):80-8. doi: 10.1016/j.plaphy.2013.12.006. [PMID: 24384414]
  • Lixia Liu, Lei Zhang, Wei Tang, Yang Gu, Qiang Hua, Sheng Yang, Weihong Jiang, Chen Yang. Phosphoketolase pathway for xylose catabolism in Clostridium acetobutylicum revealed by 13C metabolic flux analysis. Journal of bacteriology. 2012 Oct; 194(19):5413-22. doi: 10.1128/jb.00713-12. [PMID: 22865845]
  • Yuqing Xiong, Christopher DeFraia, Donna Williams, Xudong Zhang, Zhonglin Mou. Deficiency in a cytosolic ribose-5-phosphate isomerase causes chloroplast dysfunction, late flowering and premature cell death in Arabidopsis. Physiologia plantarum. 2009 Nov; 137(3):249-63. doi: 10.1111/j.1399-3054.2009.01276.x. [PMID: 19744161]
  • Aitor Alonso, Pilar Pérez, Rafael Martínez-Carrasco. Growth in elevated CO2 enhances temperature response of photosynthesis in wheat. Physiologia plantarum. 2009 Feb; 135(2):109-20. doi: 10.1111/j.1399-3054.2008.01177.x. [PMID: 19055543]
  • Michael Eicks, Verónica Maurino, Silke Knappe, Ulf-Ingo Flügge, Karsten Fischer. The plastidic pentose phosphate translocator represents a link between the cytosolic and the plastidic pentose phosphate pathways in plants. Plant physiology. 2002 Feb; 128(2):512-22. doi: 10.1104/pp.010576. [PMID: 11842155]