DL-Arginine (BioDeep_00000014863)

 

Secondary id: BioDeep_00001868685

human metabolite PANOMIX_OTCML-2023 blood metabolite


代谢物信息卡片


2-amino-5-[(diaminomethylidene)amino]pentanoic acid

化学式: C6H14N4O2 (174.1117)
中文名称: DL-精氨酸
谱图信息: 最多检出来源 Homo sapiens(lipidsearch) 18.88%

分子结构信息

SMILES: C(CC(C(=O)O)N)CN=C(N)N
InChI: InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)

描述信息

DL-Arginine is used in physicochemical analysis of amino acid complexation dynamics and crystal structure formations.
DL-Arginine is used in physicochemical analysis of amino acid complexation dynamics and crystal structure formations.

同义名列表

13 个代谢物同义名

2-amino-5-[(diaminomethylidene)amino]pentanoic acid; 2-Amino-5-(carbamimidamido)pentanoic acid; 2-Amino-5-(carbamimidamido)pentanoate; 2-Amino-5-guanidinopentanoic acid; 2-Amino-5-guanidinovaleric acid; 2-Amino-5-guanidinopentanoate; 2-Amino-5-guanidinovalerate; Amino acid(Arg-); DL-Arginine; Arginine; Arginin; Harg; Amino acid(Arg-)



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ARG1, ARHGEF12, AZIN2, CAND1, CFTR, EDN1, NOS2, NOS3, PTEN, VIM
Endosome membrane 1 CFTR
Endoplasmic reticulum membrane 2 CFTR, HSP90B1
Nucleus 8 ARG1, AZIN2, CAND1, CFTR, HSP90B1, NOS2, NOS3, PTEN
cytosol 12 ARG1, ARHGEF12, AVP, AZIN2, CAND1, CFTR, GPT, HSP90B1, NOS2, NOS3, PTEN, VIM
dendrite 2 AVP, AZIN2
phagocytic vesicle 1 VIM
trans-Golgi network 1 AZIN2
nucleoplasm 4 CAND1, NOS2, NOS3, PTEN
Cell membrane 4 CD8A, CFTR, TNF, VIM
Cytoplasmic granule 1 ARG1
Early endosome membrane 1 CFTR
Multi-pass membrane protein 1 CFTR
Synapse 1 TAC1
cell surface 2 CFTR, TNF
Golgi apparatus 2 CAND1, NOS3
Golgi membrane 2 INS, NOS3
lysosomal membrane 1 CFTR
neuronal cell body 2 TAC1, TNF
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 NOS2
plasma membrane 10 CD8A, CFTR, F2, GCG, IFNLR1, NOS2, NOS3, PTEN, TNF, VIM
Membrane 6 ARHGEF12, AZIN2, CAND1, CFTR, HSP90B1, IFNLR1
apical plasma membrane 2 CFTR, PTEN
axon 3 AZIN2, TAC1, VIM
caveola 1 NOS3
extracellular exosome 6 ARHGEF12, CAND1, F2, GPT, HSP90B1, VIM
endoplasmic reticulum 1 HSP90B1
extracellular space 8 ARG1, AVP, EDN1, F2, GCG, INS, TAC1, TNF
perinuclear region of cytoplasm 4 AZIN2, HSP90B1, NOS2, NOS3
mitochondrion 1 AZIN2
protein-containing complex 2 CFTR, HSP90B1
postsynaptic density 1 PTEN
Single-pass type I membrane protein 2 CD8A, IFNLR1
Secreted 5 AVP, EDN1, F2, GCG, INS
extracellular region 12 ARG1, AVP, CAND1, CD8A, EDN1, F2, GCG, HSP90B1, INS, PTEN, TAC1, TNF
cytoplasmic side of plasma membrane 1 PTEN
basal part of cell 1 EDN1
[Isoform 2]: Secreted 1 CD8A
external side of plasma membrane 2 CD8A, TNF
dendritic spine 1 PTEN
perikaryon 1 AZIN2
cytoplasmic vesicle 1 AZIN2
midbody 1 HSP90B1
Cytoplasm, P-body 2 NOS2, NOS3
P-body 2 NOS2, NOS3
Early endosome 1 CFTR
recycling endosome 2 CFTR, TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 CFTR
Cytoplasm, perinuclear region 1 NOS2
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 VIM
focal adhesion 2 HSP90B1, VIM
cis-Golgi network 1 AZIN2
Peroxisome 2 NOS2, VIM
peroxisomal matrix 1 NOS2
Cell projection, dendritic spine 1 PTEN
Nucleus, PML body 1 PTEN
PML body 1 PTEN
collagen-containing extracellular matrix 2 F2, HSP90B1
secretory granule 1 AVP
intermediate filament 1 VIM
receptor complex 1 CD8A
Cell projection, neuron projection 1 PTEN
neuron projection 2 PTEN, VIM
cell leading edge 1 VIM
cell projection 1 PTEN
phagocytic cup 1 TNF
cytoskeleton 2 NOS3, VIM
blood microparticle 1 F2
Recycling endosome membrane 1 CFTR
endosome lumen 1 INS
chloride channel complex 1 CFTR
microtubule organizing center 1 VIM
Melanosome 1 HSP90B1
Golgi-associated vesicle membrane 1 CFTR
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 1 NOS3
sperm plasma membrane 1 HSP90B1
intermediate filament cytoskeleton 1 VIM
ubiquitin ligase complex 1 CAND1
plasma membrane raft 1 CD8A
ficolin-1-rich granule lumen 1 CAND1
secretory granule lumen 3 CAND1, GCG, INS
Golgi lumen 2 F2, INS
endoplasmic reticulum lumen 4 F2, GCG, HSP90B1, INS
nuclear matrix 1 VIM
specific granule lumen 1 ARG1
endocytic vesicle membrane 1 NOS3
transport vesicle 3 AZIN2, EDN1, INS
Schmidt-Lanterman incisure 1 PTEN
azurophil granule lumen 1 ARG1
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 AZIN2, INS
neuronal dense core vesicle 1 AVP
Nucleus matrix 1 VIM
clathrin-coated endocytic vesicle membrane 2 AVP, CFTR
Sarcoplasmic reticulum lumen 1 HSP90B1
endoplasmic reticulum-Golgi intermediate compartment 1 AZIN2
[Isoform 1]: Cell membrane 1 CD8A
Golgi apparatus, cis-Golgi network 1 AZIN2
endocytic vesicle lumen 1 HSP90B1
[Glucagon-like peptide 1]: Secreted 1 GCG
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD8A
cortical cytoskeleton 1 NOS2
rough endoplasmic reticulum lumen 1 EDN1
Weibel-Palade body 1 EDN1
endoplasmic reticulum chaperone complex 1 HSP90B1
myelin sheath adaxonal region 1 PTEN
[Isoform alpha]: Secreted 1 PTEN
cullin-RING ubiquitin ligase complex 1 CAND1
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
granular vesicle 1 AZIN2


文献列表

  • Anna D Gajda, Małgorzata Pawełczak, Marcin Drag. Substrate specificity screening of oat (Avena sativa) seeds aminopeptidase demonstrate unusually broad tolerance in S1 pocket. Plant physiology and biochemistry : PPB. 2012 May; 54(?):6-9. doi: 10.1016/j.plaphy.2012.02.006. [PMID: 22366636]
  • Scott C Forbes, Gordon J Bell. The acute effects of a low and high dose of oral L-arginine supplementation in young active males at rest. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 2011 Jun; 36(3):405-11. doi: 10.1139/h11-035. [PMID: 21574873]
  • Antonio Pirodda, Gian Gaetano Ferri, Claudio Borghi. About plasma arginin vasopressin levels and Meniere's disease. International journal of audiology. 2011 Jan; 50(1):63; author reply 64. doi: 10.3109/14992027.2010.519726. [PMID: 21077807]
  • Oliver Fiehn, W Timothy Garvey, John W Newman, Kerry H Lok, Charles L Hoppel, Sean H Adams. Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. PloS one. 2010 Dec; 5(12):e15234. doi: 10.1371/journal.pone.0015234. [PMID: 21170321]
  • C Perez-Carbajal, D Caldwell, M Farnell, K Stringfellow, S Pohl, G Casco, A Pro-Martinez, C A Ruiz-Feria. Immune response of broiler chickens fed different levels of arginine and vitamin E to a coccidiosis vaccine and Eimeria challenge. Poultry science. 2010 Sep; 89(9):1870-7. doi: 10.3382/ps.2010-00753. [PMID: 20709971]
  • Katerina Schwarzerová, Zuzana Vondráková, Lukás Fischer, Petra Boríková, Erica Bellinvia, Katerina Eliásová, Lenka Havelková, Jindriska Fiserová, Martin Vágner, Zdenek Opatrný. The role of actin isoforms in somatic embryogenesis in Norway spruce. BMC plant biology. 2010 May; 10(?):89. doi: 10.1186/1471-2229-10-89. [PMID: 20478025]
  • M Gabriel, U Andergassen, D Putzer, A Kroiss, D Waitz, E Von Guggenberg, D Kendler, I J Virgolini. Individualized peptide-related-radionuclide-therapy concept using different radiolabelled somatostatin analogs in advanced cancer patients. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 2010 Feb; 54(1):92-9. doi: . [PMID: 20168291]
  • Carole Deyts, Beatriz Galan-Rodriguez, Elodie Martin, Nicolas Bouveyron, Emmanuel Roze, Delphine Charvin, Jocelyne Caboche, Sandrine Bétuing. Dopamine D2 receptor stimulation potentiates PolyQ-Huntingtin-induced mouse striatal neuron dysfunctions via Rho/ROCK-II activation. PloS one. 2009 Dec; 4(12):e8287. doi: 10.1371/journal.pone.0008287. [PMID: 20016831]
  • Mahbubeh Setorki, Sedighe Asgary, Akram Eidi, Ali Haeri Rohani, Nafiseh Esmaeil. Effects of apple juice on risk factors of lipid profile, inflammation and coagulation, endothelial markers and atherosclerotic lesions in high cholesterolemic rabbits. Lipids in health and disease. 2009 Oct; 8(?):39. doi: 10.1186/1476-511x-8-39. [PMID: 19804641]
  • Hiroyuki Sano, Jungo Terasaki, Chiharu Tsutsumi, Akihisa Imagawa, Toshiaki Hanafusa. A case of fulminant type 1 diabetes mellitus after influenza B infection. Diabetes research and clinical practice. 2008 Mar; 79(3):e8-9. doi: 10.1016/j.diabres.2007.10.030. [PMID: 18177974]
  • Piotr Markowski, Irena Baranowska, Jacek Baranowski. Simultaneous determination of L-arginine and 12 molecules participating in its metabolic cycle by gradient RP-HPLC method: application to human urine samples. Analytica chimica acta. 2007 Dec; 605(2):205-17. doi: 10.1016/j.aca.2007.10.033. [PMID: 18036385]
  • Wolfgang Fischer, Zoltan Zadori, Yvonne Kullnick, Helke Gröger-Arndt, Heike Franke, Kerstin Wirkner, Peter Illes, Peter P Mager. Conserved lysin and arginin residues in the extracellular loop of P2X(3) receptors are involved in agonist binding. European journal of pharmacology. 2007 Dec; 576(1-3):7-17. doi: 10.1016/j.ejphar.2007.07.068. [PMID: 17764672]
  • Harald Murck, Katja Held, Marc Ziegenbein, Heike Künzel, Kathrin Koch, Axel Steiger. The renin-angiotensin-aldosterone system in patients with depression compared to controls--a sleep endocrine study. BMC psychiatry. 2003 Oct; 3(?):15. doi: 10.1186/1471-244x-3-15. [PMID: 14585110]
  • A I Hozhenko, O S Fedoruk, I V Pohorila. [Influence of arginine on the renal functional condition of rats in sublimate nephropathy]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). 2002; 48(6):26-30. doi: NULL. [PMID: 12577465]
  • Sabri Djelidi, Ahmed Beggah, Nathalie Courtois-Coutry, Michel Fay, Francoise Cluzeaud, Say Viengchareun, Jean-Pierre Bonvalet, Nicolette Farman, Marcel Blot-Chabaud. Basolateral translocation by vasopressin of the aldosterone-induced pool of latent Na-K-ATPases is accompanied by alpha1 subunit dephosphorylation: study in a new aldosterone-sensitive rat cortical collecting duct cell line. Journal of the American Society of Nephrology : JASN. 2001 Sep; 12(9):1805-1818. doi: 10.1681/asn.v1291805. [PMID: 11518773]