6-Acetylmorphine (BioDeep_00000001413)

 

Secondary id: BioDeep_00000397507

human metabolite Endogenous natural product


代谢物信息卡片


10-hydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10,15-tetraen-14-yl acetate

化学式: C19H21NO4 (327.1471)
中文名称: 甲醇(6 -乙酰吗啡), 6-乙酰吗啡
谱图信息: 最多检出来源 Mus musculus(natural_products) 1.94%

分子结构信息

SMILES: CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)O)CCN3C
InChI: InChI=1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3

描述信息

6-acetylmorphine belongs to the family of Morphinans. These are polycyclic compounds with a four-ring skeleton with three condensed six-member rings forming a partially hydrogenated phenanthrene moiety, one of which is aromatic while the two others are alicyclic.
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids

同义名列表

16 个代谢物同义名

10-hydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10,15-tetraen-14-yl acetate; 6-O-Monoacetylmorphine hydrochloride, (5alpha,6alpha)-isomer; 6-O-Monoacetylmorphine; O6 Monoacetylmorphine; a-Monoacetyl-morphine; 6-Monoacetylmorphine; 6-(0-Acetyl)morphine; Morphine 6-acetate; Morphine-6-acetate; 6-O-Acetylmorphine; Monoacetylmorphine; 6-acetylmorphine; 6-MAM CPD; 6-MAM; 6-Acetylmorphine; 6-Acetylmorphine



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(1)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ANXA5, BCL2, CASP3, CES1, DLK1, PFDN5, POMC, SRMS
Peripheral membrane protein 1 ANXA5
Endosome membrane 1 SLC6A4
Endoplasmic reticulum membrane 1 BCL2
Nucleus 4 BCL2, CASP3, CES1, PFDN5
cytosol 7 ANXA5, BCL2, CASP3, CES1, PFDN5, PRF1, SRMS
dendrite 3 HTR2C, OPRM1, PDYN
nucleoplasm 1 CASP3
Cell membrane 5 HTR2C, OPRD1, OPRM1, PRF1, SLC6A4
Cell projection, axon 1 OPRM1
Multi-pass membrane protein 5 HTR2C, OPRD1, OPRM1, PRF1, SLC6A4
Synapse 5 HTR2C, NPS, OPRM1, PDYN, SLC6A4
glutamatergic synapse 1 CASP3
Golgi apparatus 1 OPRM1
neuronal cell body 2 CASP3, PDYN
presynaptic membrane 2 OPRD1, SLC6A4
sarcolemma 1 ANXA5
Presynapse 1 SLC6A4
endosome 1 OPRM1
plasma membrane 9 BCHE, HTR2C, IGHE, OPRD1, OPRM1, PDYN, PRF1, SLC6A4, SRMS
synaptic vesicle membrane 1 OPRD1
Membrane 7 ANXA5, BCL2, DLK1, OPRD1, OPRM1, PRF1, SLC6A4
axon 1 OPRM1
extracellular exosome 1 ANXA5
endoplasmic reticulum 3 BCL2, CES1, OPRM1
extracellular space 7 BCHE, DLK1, IGHE, IL10, IL2, POMC, TPSAB1
mitochondrion 1 BCL2
protein-containing complex 1 BCL2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 IGHE
Secreted 6 BCHE, IL10, IL2, PDYN, POMC, PRF1
extracellular region 10 ANXA5, BCHE, IGHE, IL10, IL2, NPS, PDYN, POMC, PRF1, TPSAB1
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 2 BCL2, DLK1
mitochondrial outer membrane 1 BCL2
hippocampal mossy fiber to CA3 synapse 1 PDYN
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 ANXA5
perikaryon 1 OPRM1
postsynaptic membrane 1 SLC6A4
Membrane raft 1 SLC6A4
pore complex 1 BCL2
Cell junction, focal adhesion 1 SLC6A4
focal adhesion 2 ANXA5, SLC6A4
collagen-containing extracellular matrix 1 ANXA5
secretory granule 1 POMC
Cell projection, neuron projection 1 SLC6A4
Zymogen granule membrane 1 ANXA5
neuron projection 3 OPRD1, OPRM1, SLC6A4
IgE immunoglobulin complex 1 IGHE
blood microparticle 1 BCHE
[Isoform 2]: Cell membrane 1 IGHE
Endomembrane system 1 SLC6A4
endosome lumen 1 PRF1
Lipid droplet 1 CES1
Cell projection, dendrite 1 OPRM1
myelin sheath 1 BCL2
intermediate filament cytoskeleton 1 PFDN5
secretory granule lumen 1 POMC
endoplasmic reticulum lumen 2 BCHE, CES1
axon terminus 2 OPRD1, PDYN
postsynaptic density membrane 1 OPRD1
immunological synapse 1 PRF1
neuronal dense core vesicle 2 OPRD1, PDYN
nuclear envelope lumen 1 BCHE
vesicle membrane 1 ANXA5
prefoldin complex 1 PFDN5
death-inducing signaling complex 1 CASP3
dendrite membrane 1 OPRD1
[Isoform 3]: Cell membrane 1 IGHE
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
endothelial microparticle 1 ANXA5
Cytolytic granule 1 PRF1
cytolytic granule lumen 1 PRF1
BAD-BCL-2 complex 1 BCL2
G protein-coupled serotonin receptor complex 1 HTR2C
serotonergic synapse 1 SLC6A4
[Isoform 12]: Cytoplasm 1 OPRM1
spine apparatus 1 OPRD1


文献列表

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