Deltorphin (BioDeep_00000012023)
代谢物信息卡片
化学式: C44H62N10O10S2 (954.4092)
中文名称: 啡肽
谱图信息:
最多检出来源 Mentha canadensis(plant) 100%
分子结构信息
SMILES: CC(C)CC(C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)N)NC(=O)C(CC1=CN=CN1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCSC)NC(=O)C(CC3=CC=C(C=C3)O)N
InChI: InChI=1S/C44H62N10O10S2/c1-25(2)18-34(42(62)50-32(15-17-66-4)40(60)51-33(38(46)58)22-37(56)57)52-44(64)36(21-28-23-47-24-48-28)54-43(63)35(20-26-8-6-5-7-9-26)53-41(61)31(14-16-65-3)49-39(59)30(45)19-27-10-12-29(55)13-11-27/h5-13,23-25,30-36,55H,14-22,45H2,1-4H3,(H2,46,58)(H,47,48)(H,49,59)(H,50,62)(H,51,60)(H,52,64)(H,53,61)(H,54,63)(H,56,57)/t30-,31+,32-,33-,34-,35-,36-/m0/s1
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:81455
- KEGG: C18010
- PubChem: 3035060
- Metlin: METLIN72002
- ChEMBL: CHEMBL20775
- CAS: 119975-64-3
- PMhub: MS000026283
- PubChem: 96024230
- KNApSAcK: 81455
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Faye A Bradbury, Jennifer C Zelnik, John R Traynor. G protein independent phosphorylation and internalization of the delta-opioid receptor.
Journal of neurochemistry.
2009 Jun; 109(5):1526-35. doi:
10.1111/j.1471-4159.2009.06082.x. [PMID: 19344370] - Rüdiger Schulz, Daniela A Eisinger, Andrea Wehmeyer. Opioid control of MAP kinase cascade.
European journal of pharmacology.
2004 Oct; 500(1-3):487-97. doi:
10.1016/j.ejphar.2004.07.010. [PMID: 15464054] - Magdalena Chadzinska, Barbara Plytycz. Differential migratory properties of mouse, fish, and frog leukocytes treated with agonists of opioid receptors.
Developmental and comparative immunology.
2004 Jul; 28(9):949-58. doi:
10.1016/j.dci.2004.02.003. [PMID: 15183035] - Joan Smith Sonneborn, Henry Gottsch, Eric Cubin, Peter Oeltgen, Paul Thomas. Alternative strategy for stress tolerance: opioids.
The journals of gerontology. Series A, Biological sciences and medical sciences.
2004 May; 59(5):433-40. doi:
10.1093/gerona/59.5.b433. [PMID: 15123752] - C Lacombe, C Cifuentes-Diaz, I Dunia, M Auber-Thomay, P Nicolas, M Amiche. Peptide secretion in the cutaneous glands of South American tree frog Phyllomedusa bicolor: an ultrastructural study.
European journal of cell biology.
2000 Sep; 79(9):631-41. doi:
10.1078/0171-9335-00085. [PMID: 11043404] - M Gastard. Delta-opioid receptor endocytosis in spinal cord after dermenkephalin activation.
BMC neuroscience.
2000; 1(?):1. doi:
10.1186/1471-2202-1-1. [PMID: 11151092] - M Bondanelli, M R Ambrosio, P Franceschetti, R Guerrini, A Valentini, E C degli Uberti. Effect of delta-opioid receptor agonist deltorphin on circulating concentrations of luteinizing hormone and follicle stimulating hormone in healthy fertile women.
Human reproduction (Oxford, England).
1998 May; 13(5):1159-62. doi:
10.1093/humrep/13.5.1159. [PMID: 9647539] - Y Sasaki, T Chiba. Novel deltorphin heptapeptide analogs with potent delta agonist, delta antagonist, or mixed mu antagonist/delta agonist properties.
Journal of medicinal chemistry.
1995 Sep; 38(20):3995-9. doi:
10.1021/jm00020a013. [PMID: 7562933] - E C degli Uberti, F Petraglia, M Bondanelli, A L Guo, A Valentini, S Salvadori, M Criscuolo, R E Nappi, A R Genazzani. Involvement of mu-opioid receptors in the modulation of pituitary-adrenal axis in normal and stressed rats.
Journal of endocrinological investigation.
1995 Jan; 18(1):1-7. doi:
10.1007/bf03349688. [PMID: 7759779] - E C degli Uberti, M R Ambrosio, L Vergnani, F Portaluppi, M Bondanelli, G Trasforini, A Margutti, S Salvadori. Stress-induced activation of sympathetic nervous system is attenuated by the delta-opioid receptor agonist deltorphin in healthy man.
The Journal of clinical endocrinology and metabolism.
1993 Dec; 77(6):1490-4. doi:
10.1210/jcem.77.6.8263131. [PMID: 8263131] - M Marastoni, R Tomatis, G Balboni, S Salvadori, L H Lazarus. On the degradation of the deltorphin peptides by plasma and brain homogenate.
Farmaco (Societa chimica italiana : 1989).
1991 Nov; 46(11):1273-9. doi:
. [PMID: 1667359] - J Pairault. [The coupling of beta1-24-corticotropin to the adenylate-cylase system in rat adipocytes. Evidence for hormone-nucleotides interaction (author's transl)].
European journal of biochemistry.
1976 Feb; 62(2):323-34. doi:
10.1111/j.1432-1033.1976.tb10164.x. [PMID: 3415]
