5-Formyluracil (BioDeep_00000011594)

   


代谢物信息卡片


Uracil 5-carbaldehyde

化学式: C5H4N2O3 (140.0222)
中文名称: 尿嘧啶-5-甲醛, 5-甲酰尿嘧啶
谱图信息: 最多检出来源 Homo sapiens(otcml) 30.16%

分子结构信息

SMILES: C1=C(C(=O)NC(=O)N1)C=O
InChI: InChI=1S/C5H4N2O3/c8-2-3-1-6-5(10)7-4(3)9/h1-2H,(H2,6,7,9,10)

描述信息

A pyrimidone resulting from the formal oxidation of the alcoholic hydroxy group of 5-hydroxymethyluracil to the corresponding aldehyde. It is a major one-electron photooxidation product of thymine in oligodeoxynucleotides.
D009676 - Noxae > D009153 - Mutagens

同义名列表

4 个代谢物同义名

5-Formyluracil; Uracil 5-carbaldehyde; Uracil 5-carbaldehyde; 5-Formyluracil



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 OAZ1, PMP2, POLB, POLR2A, PTPN2, TYMS, XPC
Nucleus 19 CD274, JUND, MBD4, OAZ1, PCNA, PMP2, POLB, POLI, POLL, POLR2A, PTPN2, RAD23B, RPA1, SMUG1, SSBP1, TDG, TYMS, UNG, XPC
cytosol 7 OAZ1, PMP2, PTPN2, RAD23B, SMUG1, TYMS, XPC
nuclear body 1 PCNA
centrosome 1 PCNA
nucleoplasm 15 CD274, JUND, MBD4, PCNA, POLB, POLI, POLL, POLR2A, PTPN2, RAD23B, RPA1, SMUG1, TDG, UNG, XPC
RNA polymerase II transcription regulator complex 1 JUND
Cell membrane 2 CD274, PDCD1
Early endosome membrane 1 CD274
mitochondrial inner membrane 1 TYMS
plasma membrane 5 CD274, PDCD1, PTPN2, TDG, XPC
Membrane 2 PDCD1, PTPN2
extracellular exosome 4 CD274, PCNA, PMP2, SSBP1
endoplasmic reticulum 1 PTPN2
mitochondrion 4 SSBP1, TYMS, UNG, XPC
protein-containing complex 1 POLB
intracellular membrane-bounded organelle 1 XPC
Single-pass type I membrane protein 1 CD274
Mitochondrion matrix 1 TYMS
mitochondrial matrix 2 SSBP1, TYMS
transcription regulator complex 1 JUND
external side of plasma membrane 2 CD274, PDCD1
actin cytoskeleton 1 CD274
nucleolus 2 SMUG1, XPC
Mitochondrion inner membrane 1 TYMS
microtubule 1 POLB
mitochondrial nucleoid 1 SSBP1
Nucleus, PML body 1 RPA1
PML body 2 RPA1, TDG
nuclear speck 2 MBD4, POLI
chromatin 3 JUND, PCNA, XPC
Chromosome 3 POLL, POLR2A, XPC
cytoplasmic ribonucleoprotein granule 1 POLI
[Isoform 1]: Endoplasmic reticulum 1 PTPN2
nuclear replication fork 1 PCNA
chromosome, telomeric region 2 PCNA, RPA1
site of double-strand break 2 POLL, RPA1
fibrillar center 1 SMUG1
Recycling endosome membrane 1 CD274
Endomembrane system 1 PTPN2
endosome lumen 1 PTPN2
euchromatin 1 POLR2A
replication fork 1 PCNA
myelin sheath 1 PMP2
proteasome complex 1 RAD23B
transcription repressor complex 1 JUND
male germ cell nucleus 1 PCNA
nuclear lamina 1 PCNA
endoplasmic reticulum-Golgi intermediate compartment 1 PTPN2
spindle microtubule 1 POLB
RNA polymerase II, core complex 1 POLR2A
[Isoform 1]: Cell membrane 1 CD274
[Isoform 4]: Secreted 1 CD274
site of DNA damage 2 RPA1, XPC
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
transcription factor AP-1 complex 1 JUND
nucleotide-excision repair complex 1 XPC
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
DNA replication factor A complex 1 RPA1
Mitochondrion matrix, mitochondrion nucleoid 1 SSBP1
XPC complex 2 RAD23B, XPC
nucleotide-excision repair factor 2 complex 1 XPC
nuclear lumen 1 POLR2A
DNA-directed RNA polymerase complex 1 POLR2A
[Isoform 2]: Endomembrane system 1 CD274


文献列表

  • H Miyazaki, Y Matsunaga, M Hashimoto, N Sunahara, K Yokogawa. A simple method to determine inhibitory activity of xanthine oxidase in vivo. Japanese journal of pharmacology. 1982 Apr; 32(2):400-3. doi: 10.1254/jjp.32.400. [PMID: 6896536]