Aminopropylcadaverine (BioDeep_00000011271)
Secondary id: BioDeep_00001872126
human metabolite Endogenous natural product
代谢物信息卡片
化学式: C8H21N3 (159.1735)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(plant) 11.77%
分子结构信息
SMILES: C(CCN)CCNCCCN
InChI: InChI=1S/C8H21N3/c9-5-2-1-3-7-11-8-4-6-10/h11H,1-10H2
描述信息
Aminopropylcadaverine,a polyamine, is the final product of aminopropylcadaverine biosynthesis pathway. Polyamines are important for cell growth and are believed to be involved in many processes including DNA, RNA, and protein synthesis, as well as membrane integrity and resistance to stress, to name a few. Cadaverine and aminopropylcadaverine are alternative polyamines that can at least partially substitute for purtrescine and spermidine, the primary polyamines found in E. coli. Lysine is decarboxylated to form cadaverine which is then converted to aminopropylcadaverine by the aminopropyltransferase, SpeE. [HMDB]
Aminopropylcadaverine,a polyamine, is the final product of aminopropylcadaverine biosynthesis pathway. Polyamines are important for cell growth and are believed to be involved in many processes including DNA, RNA, and protein synthesis, as well as membrane integrity and resistance to stress, to name a few. Cadaverine and aminopropylcadaverine are alternative polyamines that can at least partially substitute for purtrescine and spermidine, the primary polyamines found in E. coli. Lysine is decarboxylated to form cadaverine which is then converted to aminopropylcadaverine by the aminopropyltransferase, SpeE.
同义名列表
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:64860
- KEGG: C16565
- PubChem: 65523
- HMDB: HMDB0012189
- Metlin: METLIN62845
- ChEMBL: CHEMBL89035
- MetaCyc: CPD0-1065
- foodb: FDB028841
- chemspider: 58969
- CAS: 56-19-9
- PMhub: MS000025243
- PubChem: 51090894
- NIKKAJI: J575.711H
- RefMet: Aminopropylcadaverine
- KNApSAcK: 64860
- LOTUS: LTS0252731
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
7 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(5)
- aminopropylcadaverine biosynthesis:
H+ + lys ⟶ CO2 + cadaverine - superpathway of polyamine biosynthesis I:
H2O + agmatine ⟶ putrescine + urea - superpathway of polyamine biosynthesis I:
H2O + agmatine ⟶ putrescine + urea - superpathway of arginine and polyamine biosynthesis:
N-acetyl-L-ornithine + H2O ⟶ L-ornithine + acetate - aminopropylcadaverine biosynthesis:
S-adenosyl-L-methioninamine + cadaverine ⟶ S-methyl-5'-thioadenosine + H+ + aminopropylcadaverine
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(2)
- Aminopropylcadaverine Biosynthesis:
Hydrogen Ion + L-Lysine ⟶ Cadaverine + Carbon dioxide - Aminopropylcadaverine Biosynthesis:
Hydrogen Ion + L-Lysine ⟶ Cadaverine + Carbon dioxide
PharmGKB(0)
6 个相关的物种来源信息
- 2 - Bacteria: LTS0252731
- 543 - Enterobacteriaceae: LTS0252731
- 561 - Escherichia: LTS0252731
- 562 - Escherichia coli: LTS0252731
- 1236 - Gammaproteobacteria: LTS0252731
- 9606 - Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- D R Walters, T Cowley, A McPherson. Polyamine metabolism in the thermotolerant mesophilic fungus Aspergillus fumigatus.
FEMS microbiology letters.
1997 Aug; 153(2):433-7. doi:
10.1111/j.1574-6968.1997.tb12607.x. [PMID: 9303883] - D R Walters, T Cowley. Formation of cadaverine derivatives in Saccharomyces cerevisiae.
FEMS microbiology letters.
1996 Dec; 145(2):255-9. doi:
10.1111/j.1574-6968.1996.tb08586.x. [PMID: 8961564] - E Hölttä, P Pohjanpelto. Polyamine starvation causes accumulation of cadaverine and its derivatives in a polyamine-dependent strain of Chinese-hamster ovary cells.
The Biochemical journal.
1983 Mar; 210(3):945-8. doi:
10.1042/bj2100945. [PMID: 6409084]
