Exact Mass: 368.1442276
Exact Mass Matches: 368.1442276
Found 500 metabolites which its exact mass value is equals to given mass value 368.1442276,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Mitraphylline
Mitraphylline is a member of indolizines. Mitraphylline is a natural product found in Uncaria tomentosa, Mitragyna parvifolia, and other organisms with data available. See also: Cats Claw (part of); Mitragyna speciosa leaf (part of). Annotation level-1 Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1]. Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1].
Uncarine
Uncarine E is a member of indolizines. Isopteropodine is a natural product found in Uncaria lanosa, Uncaria tomentosa, and other organisms with data available. See also: Cats Claw (part of). Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors[1]. Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors[1]. Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors[1].
UNCARIN C
Uncarine C is a member of indolizines. Uncarine c is a natural product found in Uncaria lanosa, Uncaria tomentosa, and other organisms with data available. See also: Cats Claw (part of).
Dehydroepiandrosterone sulfate
Dehydroepiandrosterone sulfate or DHEA-S is the sulfated form of dehydroepiandrosterone (DHEA). This sulfation is reversibly catalyzed by sulfotransferase 2A1 (SULT2A1) primarily in the adrenals, the liver, and small intestine. In the blood, most DHEA is found as DHEA-S with levels that are about 300 times higher than those of free DHEA. Orally-ingested DHEA is converted into its sulfate when passing through the intestines and liver. Whereas DHEA levels naturally reach their peak in the early morning hours, DHEAS levels show no diurnal variation. From a practical point of view, measurement of DHEA-S is preferable to DHEA since levels are more stable. DHEA (from which DHEA-S comes from) is a natural steroid prohormone produced from cholesterol by the adrenal glands, the gonads, adipose tissue, brain, and in the skin (by an autocrine mechanism). DHEA is the precursor of androstenedione, which can undergo further conversion to produce the androgen testosterone and the estrogens estrone and estradiol. DHEA is also a potent sigma-1 agonist. Serum dehydroepiandrosterone sulfate is a classic marker for adrenarche, and subsequently for the individual hormonal milieu (PMID: 10599744). Dehydroepiandrosterone sulfate is an endogenously produced sex steroid that has been hypothesized to have anti-aging effects (PMID: 16960027). It also has been inversely associated with the development of atherosclerosis (PMID: 8956025). DHEAS or Dehydroepiandrosterone sulfate is the sulfated form of DHEA. This sulfation is reversibly catalyzed by sulfotransferase (SULT2A1) primarily in the adrenals, the liver, and small intestine. In the blood, most DHEA is found as DHEAS with levels that are about 300 times higher than those of free DHEA. Orally-ingested DHEA is converted to its sulfate when passing through intestines and liver. Whereas DHEA levels naturally reach their peak in the early morning hours, DHEAS levels show no diurnal variation. From a practical point of view, measurement of DHEAS is preferable to DHEA, as levels are more stable. DHEA (from which DHEAS comes from) is a natural steroid prohormone produced from cholesterol by the adrenal glands, the gonads, adipose tissue, brain and in the skin (by an autocrine mechanism). DHEA is the precursor of androstenedione, which can undergo further conversion to produce the androgen testosterone and the estrogens estrone and estradiol. DHEA is also a potent sigma-1 agonist. DHEAS can serve as a precursor for testosterone; androstenedione; estradiol; and estrone. [HMDB] D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Curcumin
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials relative retention time with respect to 9-anthracene Carboxylic Acid is 1.286 D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents D000970 - Antineoplastic Agents D018501 - Antirheumatic Agents D004791 - Enzyme Inhibitors D004396 - Coloring Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS relative retention time with respect to 9-anthracene Carboxylic Acid is 1.290 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.289 [Raw Data] CBA71_Curcumin_neg_10eV.txt [Raw Data] CBA71_Curcumin_neg_30eV.txt [Raw Data] CBA71_Curcumin_neg_40eV.txt [Raw Data] CBA71_Curcumin_pos_30eV.txt [Raw Data] CBA71_Curcumin_pos_20eV.txt [Raw Data] CBA71_Curcumin_pos_40eV.txt [Raw Data] CBA71_Curcumin_neg_50eV.txt [Raw Data] CBA71_Curcumin_pos_10eV.txt [Raw Data] CBA71_Curcumin_pos_50eV.txt [Raw Data] CBA71_Curcumin_neg_20eV.txt Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification. Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
7-O-Methylluteone
A hydroxyisoflavone that is luteone in which the hydroxy group at position 7 is replaced by a methoxy group.
5-Demethoxydeoxypodophyllotoxin
D009676 - Noxae > D003603 - Cytotoxins D000970 - Antineoplastic Agents
Talactoferrin Alfa
D000970 - Antineoplastic Agents
2',4-Dihydroxy-4',6'-dimethoxy-3'-prenylchalcone
2,4-Dihydroxy-4,6-dimethoxy-3-prenylchalcone is found in alcoholic beverages. 2,4-Dihydroxy-4,6-dimethoxy-3-prenylchalcone is isolated from Humulus lupulus (hops). Isolated from Humulus lupulus (hops). 2,4-Dihydroxy-4,6-dimethoxy-3-prenylchalcone is found in alcoholic beverages.
uncarine d
Curcumin
Curcumin appears as orange-yellow needles. (NTP, 1992) Curcumin is a beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. It has a role as a metabolite, an anti-inflammatory agent, an antineoplastic agent, a hepatoprotective agent, a flavouring agent, a biological pigment, a nutraceutical, an antifungal agent, a dye, a lipoxygenase inhibitor, a ligand, a radical scavenger, a contraceptive drug, an EC 3.5.1.98 (histone deacetylase) inhibitor, an immunomodulator, an iron chelator, a neuroprotective agent, a food colouring, an EC 1.1.1.21 (aldehyde reductase) inhibitor, an EC 1.1.1.25 (shikimate dehydrogenase) inhibitor, an EC 1.1.1.205 (IMP dehydrogenase) inhibitor, an EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor, an EC 1.8.1.9 (thioredoxin reductase) inhibitor, an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor and a geroprotector. It is a polyphenol, a beta-diketone, an enone, a diarylheptanoid and an aromatic ether. It is functionally related to a ferulic acid. Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in [Curcuma xanthorrhiza oil]. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wound-healing, and antimicrobial activities. Due to these properties, curcumin has been investigated for the treatment and supportive care of clinical conditions including proteinuria, breast cancer, multiple myeloma, depression, and Non Small Cell Lung Cancer (NSCLC). Despite proven efficacy against numerous experimental models, poor bioavailability due to poor absorption, rapid metabolism, and rapid systemic elimination have been shown to limit the therapeutic efficacy of curcumin. Curcumin is under investigation for the treatment and supportive care of various clinical conditions including mucositis, rectal cancer, prostate cancer, chronic schizophrenia, and Mild Cognitive Impairment (MCI). curcumin is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). Curcumin is a natural product found in Strychnos angustiflora, Curcuma amada, and other organisms with data available. Curcumin is a phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties. Curcumin blocks the formation of reactive-oxygen species, possesses anti-inflammatory properties as a result of inhibition of cyclooxygenases (COX) and other enzymes involved in inflammation; and disrupts cell signal transduction by various mechanisms including inhibition of protein kinase C. These effects may play a role in the agents observed antineoplastic properties, which include inhibition of tumor cell proliferation and suppression of chemically induced carcinogenesis and tumor growth in animal models of cancer. (NCI04) A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes. See also: ... View More ... Curcumin is a natural component of the rhizome of turmeric (Curcuma longa) and one of the most powerful chemopreventive and anticancer agents. Its biological effects range from antioxidant, anti-inflammatory to inhibition of angiogenesis and is also shown to possess specific antitumoral activity. The molecular mechanism of its varied cellular effects has been studied in some details and it has been shown to have multiple targets and interacting macromolecules within the cell. Curcumin has been shown to possess anti-angiogenic properties and the angioinhibitory effects of curcumin manifest due to down regulation of proangiogenic genes such as VEGF and angiopoitin and a decrease in migration and invasion of endothelial cells. One of the important factors implicated in chemoresistance and induced chemosensitivity is NFkB and curcumin has been shown to down regulate NFkB and inhibit IKB kinase thereby suppressing proliferation and inducing apoptosis. Cell lines that are resistant to certain apoptotic inducers and radiation become susceptible to apoptosis when treated in conjunction with curcumin. Besides this it can also act as a chemopreventive agent in cancers of colon, stomach and skin by suppressing colonic aberrant crypt foci formation and DNA adduct formation. This review focuses on the various aspects of curcumin as a potential drug for cancer treatment and its implications in a variety of biological and cellular processes vis-à-vis its mechanism of action (PMID: 16712454). Turmeric (Zingiberaceae family) rhizomes, has been widely used for centuries in indigenous medicine for the treatment of a variety of inflammatory conditions and other diseases. Its medicinal properties have been attributed mainly to the curcuminoids and the main component present in the rhizome is curcumin. Curcumin has been shown to possess wide range of pharmacological activities including anti-inflammatory, anti-cancer, anti-oxidant, wound healing and anti-microbial effects. Recently, curcumin treatment has been shown to correct defects associated with cystic fibrosis in homozygous DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) knock out mice. In vivo and in vitro studies have demonstrated curcumins ability to inhibit carcinogenesis at three stages: tumor promotion, angiogenesis and tumor growth. Curcumin suppresses mitogen-induced proliferation of blood mononuclear cells, inhibits neutrophil activation and mixed lymphocyte reaction and also inhibits both serum-induced and platelet derived growth factor (PDGF)-dependent mitogenesis of smooth muscle cells. It has also been reported to be a partial inhibitor of protein kinase. The other salient feature of turmeric/curcumin is that despite being consumed daily for centuries in Asian countries, it has not been shown to cause any toxicity (PMID: 16413584). Isolated from Curcuma zedoaria (zedoary) and other Curcuma subspecies flavouring ingredient. Natural colouring matter used extensively in Indian curries etc. Nutriceutical with anticancer and antiinflammatory props. Curcumin is found in many foods, some of which are asian pear, leek, chayote, and coconut. A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents D000970 - Antineoplastic Agents D018501 - Antirheumatic Agents D004791 - Enzyme Inhibitors D004396 - Coloring Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification. Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
Glycycoumarin
Glycycoumarin is a member of the class of coumarins that is coumarin substituted by a hydroxy group at position 7, a methoxy group at position 5, a prenyl group at position 6 and a 2,4-dihydroxyphenyl group at position 3. Isolated from Glycyrrhiza uralensis, it exhibits antispasmodic activity. It has a role as an antispasmodic drug and a plant metabolite. It is a member of coumarins, an aromatic ether and a member of resorcinols. Glycycoumarin is a natural product found in Glycyrrhiza glabra, Glycyrrhiza uralensis, and other organisms with data available. See also: Glycyrrhiza uralensis Root (part of). A member of the class of coumarins that is coumarin substituted by a hydroxy group at position 7, a methoxy group at position 5, a prenyl group at position 6 and a 2,4-dihydroxyphenyl group at position 3. Isolated from Glycyrrhiza uralensis, it exhibits antispasmodic activity. Glycycoumarin is found in root vegetables. Glycycoumarin is from licorice (Glycyrrhiza glabra From licorice (Glycyrrhiza glabra). Glycycoumarin is found in root vegetables. Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[1][2]. Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[1][2]. Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[1][2].
Isoglycycoumarin
Isoglycycoumarin is an organic hydroxy compound and an isoflavonoid. Isoglycycoumarin is a natural product found in Glycyrrhiza glabra, Glycyrrhiza uralensis, and Glycyrrhiza inflata with data available. Isoglycycoumarin is found in herbs and spices. Isoglycycoumarin is isolated from Glycyrrhiza glabra (licorice) and Glycyrrhiza uralensis (Chinese licorice). Isolated from Glycyrrhiza glabra (licorice) and Glycyrrhiza uralensis (Chinese licorice). Isoglycycoumarin is found in tea and herbs and spices.
Cyclocurcumin
Cyclocurcumin is found in herbs and spices. Cyclocurcumin is a constituent of the rhizome of Curcuma longa (turmeric). Constituent of the rhizome of Curcuma longa (turmeric). Cyclocurcumin is found in turmeric and herbs and spices. Cyclocurcumin is a diarylheptanoid.
Glicoricone
Glicoricone is a member of isoflavones. Glicoricone is a natural product found in Glycyrrhiza and Glycyrrhiza uralensis with data available. Glicoricone is found in herbs and spices. Glicoricone is a constituent of Glycyrrhiza sp Constituent of Glycyrrhiza species Glicoricone is found in herbs and spices.
Testosterone sulfate
C19H28O5S (368.16573580000005)
Testosterone is a predominantly male hormone, though females do produce certain amounts of it. The primary female hormone is estrogen and males also produce certain amounts of this hormone. testosterone causes the appearance of male traits (i.e deepening voice, pubic and facial hairs, muscular build, etc.). The keto group on C-17 is reduced to an alcohol to yield testosterone. Testosterone is a steroid hormone from the androgen group. testosterone is primarily secreted in the testes of males and the ovaries of females although small amounts are secreted by the adrenal glands. It is the principal male sex hormone and an anabolic steroid. In both males and females, it plays key roles in health and well-being. On average, the adult male body produces about twenty times the amount of testosterone that an adult females body does. Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5-alpha -dihydrotestosterone (DHT) by the cytoplasmic enzyme 5-alpha-reductase(5-alpha-reduktas). DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about 2.5 times that of T. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects. It is important to note that if there is a too low amount of 5-alpha-reductase(5-alfa-reduktas), the body (of a human) will continue growing into a female with testicles. Testerone is a predominantly male hormone, though females do produce certain amounts of it. The primary female hormone is estrogen and males also produce certain amounts of this hormone. testosterone causes the appearance of male traits (i.e deepening voice, pubic and facial hairs, muscular build, etc.) D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D000728 - Androgens
9-O-Methylglyceofuran
9-O-Methylglyceofuran is found in pulses. 9-O-Methylglyceofuran is from Glycine max (soy bean). From Glycine max (soy bean). 9-O-Methylglyceofuran is found in soy bean and pulses.
Gancaonin B
Gancaonin B is found in herbs and spices. Gancaonin B is isolated from Glycyrrhiza uralensis (Chinese licorice). Isolated from Glycyrrhiza uralensis (Chinese licorice). Gancaonin B is found in herbs and spices.
Glycyrrhizaisoflavone C
Glycyrrhizaisoflavone C is found in herbs and spices. Glycyrrhizaisoflavone C is a constituent of licorice (Glycyrrhiza sp.) Constituent of licorice (Glycyrrhiza species). Glycyrrhizaisoflavone C is found in tea and herbs and spices.
Integrin
Integrin is found in fruits. Integrin is a constituent of heartwood of Artocarpus integer (champeduk)
Mollicellin H
Mollicellin H is produced by Chaetomium species and mutagenic mycotoxin. Production by Chaetomium subspecies and mutagenic mycotoxin.
Gancaonin N
Gancaonin N is found in herbs and spices. Gancaonin N is isolated from Glycyrrhiza uralensis (Chinese licorice). Isolated from Glycyrrhiza uralensis (Chinese licorice). Gancaonin N is found in herbs and spices.
Methyl (R)-9-hydroxy-10-undecene-5,7-diynoate glucoside
Methyl (R)-9-hydroxy-10-undecene-5,7-diynoate glucoside is found in root vegetables. Methyl (R)-9-hydroxy-10-undecene-5,7-diynoate glucoside is a constituent of Helianthus tuberosus (Jerusalem artichoke). Constituent of Helianthus tuberosus (Jerusalem artichoke). Methyl (R)-9-hydroxy-10-undecene-5,7-diynoate glucoside is found in root vegetables.
(2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside]
C15H28O10 (368.16823880000004)
(2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside] is found in root vegetables. (2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside] is a constituent of the roots of cassava (Manihot esculenta). Constituent of the roots of cassava (Manihot esculenta). (2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside] is found in root vegetables.
3-methoxy-4-(3-methylbut-2-en-1-yl)-8,17-dioxatetracyclo[8.7.0.0(2),.0(1)(1),(1)]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-5,13,14-triol
9-Hydroxy-4-(3,7-dimethyl-2,6-octadienyloxy)-psoralen
9-Hydroxy-4-(3,7-dimethyl-2,6-octadienyloxy)-psoralen is found in citrus. 9-Hydroxy-4-(3,7-dimethyl-2,6-octadienyloxy)-psoralen is a constituent of Citrus medica (citron). Constituent of Citrus medica (citron). 9-Hydroxy-4-(3,7-dimethyl-2,6-octadienyloxy)-psoralen is found in citrus.
Kanzonol P
Kanzonol P is found in herbs and spices. Kanzonol P is a constituent of Glycyrrhiza uralensis (Chinese licorice). Constituent of Glycyrrhiza uralensis (Chinese licorice). Kanzonol P is found in herbs and spices.
Artocarpetin A
Artocarpetin A is found in fruits. Artocarpetin A is a constituent of Artocarpus heterophyllus (jackfruit)
4-Hydroxy-3-prenylbenzoic acid glucoside
4-Hydroxy-3-prenylbenzoic acid glucoside is found in nuts. 4-Hydroxy-3-prenylbenzoic acid glucoside is a constituent of almond hulls (Prunus amygdalus). Constituent of almond hulls (Prunus amygdalus). 4-Hydroxy-3-prenylbenzoic acid glucoside is found in nuts.
Cyclointegrin
Cyclointegrin is found in fruits. Cyclointegrin is isolated from heartwood of Artocarpus integer (champedak
trans-3-Hydroxycotinine glucuronide
3-Hydroxycotinine (3HC) is the main nicotine metabolite detected in smokers urine. It is also excreted as a glucuronide conjugate (3HC-Gluc). 3HC and 3HC-Gluc account for 40-60\\% of the nicotine dose in urine. [HMDB] 3-Hydroxycotinine (3HC) is the main nicotine metabolite detected in smokers urine. It is also excreted as a glucuronide conjugate (3HC-Gluc). 3HC and 3HC-Gluc account for 40-60\\% of the nicotine dose in urine.
Epitestosterone sulfate
C19H28O5S (368.16573580000005)
Epitestosterone Sulfate is a sulfate conjugate of endogenous steroids hormone epitestosterone produced by both sexes and was determined using LC-MS/MS. A human metabolite taken as a putative food compound of mammalian origin [HMDB]
N-Desmethyleletriptan
N-Desmethyleletriptan is only found in individuals that have used or taken Eletriptan. N-Desmethyleletriptan is a metabolite of Eletriptan. N-desmethyleletriptan belongs to the family of Indoles. These are compounds containing an indole moiety, which consists of pyrrole ring fused to benzene to form 2,3-benzopyrrole.
(1E,6E)-1,7-Bis(3-methoxy-4-hydroxyphenyl)-5-hydroxy-1,4,6-heptatriene-3-one
2-Hydroxyestradiol 17-sulfate
3-Hydroxycotinine glucuronide
AB-Fubinaca
C20H21FN4O2 (368.16484579999997)
[(2R,5S,15S)-2,15-Dimethyl-14-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-yl]oxidanesulfonic acid
C19H28O5S (368.16573580000005)
5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid
Benzamide, N-(2-chloro-2-phenyl-1-(1-piperidinylcarbonyl)ethenyl)-
1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
Dialdehyde
Estriol 3-sulfate
1-(5-Cyanopyridin-2-yl)-3-((1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl)urea
Cyclohexanol, 4-(4-(4-fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl)-, trans-
C20H21FN4O2 (368.16484579999997)
1,3-Dimethoxymethyl-5,5-diphenylbarbituric acid
Icartin
Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC). Icaritin is a natural product found in Epimedium diphyllum, Epimedium wushanense, and other organisms with data available. Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 μM) and primary CML cells (IC50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis[1][2][3. Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 μM) and primary CML cells (IC50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis[1][2][3.
Sophoflavescenol
Sophoflavescenol is a natural product found in Albizia julibrissin and Sophora flavescens with data available.
Isoanhydroicaritin
Isoanhydroicaritin is a natural product found in Sophora flavescens with data available.
Anhydroicaritin
beta-Anhydroicaritin is a natural product found in Epimedium brevicornu with data available. β-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties[1]. β-Anhydroicaritin ameliorates the degradation of periodontal tissue and inhibits the synthesis and secretion of TNF-α and MMP-3 in diabetic rats[2]. β-Anhydroicaritin decreases the overproduction of NO, IL-10, TNF-α, MCP-1 and IL-6 in inperitonitis mice. β-Anhydroicaritin inhibits the elevation of intracellular Ca2+, and markedly decreases iNOS protein expression[3]. β-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties[1]. β-Anhydroicaritin ameliorates the degradation of periodontal tissue and inhibits the synthesis and secretion of TNF-α and MMP-3 in diabetic rats[2]. β-Anhydroicaritin decreases the overproduction of NO, IL-10, TNF-α, MCP-1 and IL-6 in inperitonitis mice. β-Anhydroicaritin inhibits the elevation of intracellular Ca2+, and markedly decreases iNOS protein expression[3].
Sinapine thiocyanate
Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species. Sinapine thiocyanate exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease[1][2][3][4]. Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species. Sinapine thiocyanate exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease[1][2][3][4].
8alpha-Acetoxy-10alpha-hydroxy-13-O-methylhirsutinolide
Quercetol C
Glycyrrhisoflavanone
Leiocinol
Edulane
Kaerophyllin
Kaerophyllin is a natural product found in Montrouziera sphaeroidea, Bupleurum salicifolium, and other organisms with data available.
5,4-Dihydroxy-5-(1-hydroxy-1-methylethyl)-4-methoxyfurano[2,3:7,6]isoflavone
Ugonin C
Louisfieserone A
4-Hydroxy-5-methoxy-7-(3-methyl-2,3-epoxybutoxy)flavone
Glyasperin H
Spherosinin
Canniflavone
Topazolin
Ciliatin B
(2S)-5,3-Dihydroxy-4-methoxy-6,6-dimethylpyrano[2,3:7,8]flavanone
(2S)-4,5-Dihydroxy-8-hydroxymethyl-6,6-dimethylpyrano[2,3:7,6]flavanone
5,7,4-trihydroxy-3-(3-methylbut-2-enyl)-3-methoxy flavone
Kwakhurin
Licoarylcoumarin
A member of the class of coumarins that is coumarin substituted by a hydroxy group at position 7, a methoxy group at position 5, a 2-methylbut-3-en-2yl group at position 8 and a 2,4-dihydroxyphenyl group at position 3. It has been isolated from Glycyrrhiza uralensis.
Cyclointegrin
Isoglycycoumarin
Glycycoumarin
Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[1][2]. Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[1][2]. Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases[1][2].
Integrin
Estriol 17-sulfate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide
C20H21FN4O2 (368.16484579999997)
3,4-Dichloro-N-[[1-(1-piperidinyl)cyclohexyl]methyl]-benzamide
2-[(E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]oxyethyl-trimethylazanium;thiocyanate
11-ethyl-5,6-dioxo-5,6,8,9,10,11,12,14-octahydro-4bH-7,14-diaza-7,11-methano-cycloundeca[a]indene-13-carboxylic acid methyl ester|Ervinidin
4-(3,4,8,9-Tetrahydro-8-isopropenyl-5-methoxy-2H-furo[2,3-h]-1-benzopyran-3-yl)-3-methoxyphenol
beta-(trans-3,4-methylenedioxybenzylidene)-alpha-(3,4-dimethoxybenzyl)-gamma-butyrolactone
2-Ac-3-O-alpha-L-Rhamnopyranosyl-D-galactose
C14H24O11 (368.13185539999995)
3-(3-methylbut-2-enyloxy)-4-O-alpha-D-ribofuranose benzoic acid methyl ester
(2S)-5,7-Dimethoxy-8-(2R-hydroxy-3-methyl-3-butenyl)-flavanone
(+/-)-jatrophan|(3E)-<3,4-(methylenedioxy)benzylidene>-4-(3,4-dimethoxybenzyl)-gamma-butyrolactone|(E)-alpha-(3,4-methylenedioxybenzylidene)-beta-(3,4-dimethoxybenzyl)-gamma-butyrolactone|(S,E)-4-(3,4-Dimethoxybenzyl)-4,5-dihydro-3-(3,4-methylenedioxybenzylidene)-2(3H)-furanone|alpha-(trans-3,4-methylenedioxybenzylidene)-beta-(3,4-dimethoxybenzyl)-gamma-butyrolactone|jatrophan|succilactone|suchilactone
1-formyl-19-hydroxy-17-methoxy-aspidospermidin-21-oic acid lactone|1-Formyl-19-hydroxy-17-methoxy-aspidospermidin-21-saeure-lacton|Dichotamin|dichotamine
(-)-(2S)-5,3-dihydroxy-4-methoxy-6,6-dimethylchromeno-(7,8,2,3)-flavanone
lespeflorin G8
A member of the class of pterocarpans that is (6aR,11aR)-pterocarpan substituted by a hydroxy group at position 8, methoxy groups at positions 3 and 9 and a prenyl group at position 10. Isolated from the roots of Lespedeza floribunda, it acts as a melanin synthesis inhibitor.
2,4-dihydroxy-4,6-dimethoxy-3-prenylchalcone|4-O-methylxanthohumol
7-allyl-5-methoxy-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-3-methyl-benzofuran-6-ol
(3E,6xi,9R,10R)-6-chlorolauthisa-3,11-dien-1-yne-9,10-diyl diacetate
lachnophyllum acid(4-O-methyl siringenin)-ester|lachnophyllum acid<4-O-methyl siringenin>-ester
2,3-Dihydro-2-(1-hydroxy-1-methylethyl)-3-methyl-4-hydroxy-7-(4-hydroxyphenyl)-5H-furo[3,2-g][1]benzopyran-5-one
2-methylpropanyl 6-O-beta-D-apiofuranosyl-beta-D-glucopyranoside
C15H28O10 (368.16823880000004)
4,5-dihydroxy-8-hydroxymethyl-6,6-dimethylpyrano[2,3:7,6]flavanone
Egonol Acetate
An acetate ester of egonol isolated from the fruits of Styrax agrestis.
methyl (5Z,17E)-18-bromooctadeca-5,17-dien-7-ynoate
1-Phenanthrenecarboxylic acid, 6,8-dichloro-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)-
2-hydroxy-6,7-dimethoxy-2,3-dimethyl-4-piperonyltetralin-3-en-1-one
tert-Butyl glycoside-alpha-Pyranose-2-O-beta-D-Glucopyranosyl-L-arabinose
C15H28O10 (368.16823880000004)
3-(3-methyl-1-butenyl)-6-methoxy-5,7,4-trihydroxy flavone|ovalifolin
(2S,5S)-2,5-bis<(3R)-3-methyl-2,5-dioxo-piperazin-1-yl>cyclohexane-1,4-diol|(2S,5S)-2,5-bis[(3R)-3-methyl-2,5-dioxo-piperazin-1-yl]cyclohexane-1,4-diol
Phenanthrenequinone, 1,4,8-trihydroxy-2-methyl-3-(4-methylvaleryl)-
3,9-dimethoxy-2-prenyl-(6aR,11aR)pterocarpan|Erythribyssin C
(6aS,11aS)-3-hydroxy-6a,9-dimethoxy-10-(3,3-dimethylallyl)pterocarpan|Erythribyssin A
4-Me,Me glycoside,Me ester-2-O-alpha-D-Glucopyranuronosyl-D-xylose,,
C14H24O11 (368.13185539999995)
(-)-3-hydroxy-4-[(E)-2-hydroxymethyl-2-buten-4-yl]-8,9-methylenedioxypterocarpan|(-)-cabenergin A-I|cabenegrin A-I
4,5-Methylene,3-Me ether,Ac-3,4,4,5-Tetrahydroxy-2,7-cyclolignan
3(S)-7-hydroxy-2,4-dimethoxy-5-(gamma,gamma-dimethylallyl)isoflavanone|Erythribyssin E
2-O-methylalbanin A|5,7,4-trihydroxy-2-methoxy-3-(gamma,gamma-dimethylallyl)flavone
3(S)-5,7-dihydroxy-2-methoxy-[2,2-dimethyl-3,4-dehydro-pyrano-(1,4:-4,5)]isoflavanone|Erythraddison IV
2-(4-Methoxyphenyl)-3,5-dihydroxy-7-(prenyloxy)-4H-1-benzopyran-4-one
3-[2,6-Dihydroxy-3-(3-methyl-2-butenyl)-4-methoxyphenyl]-7-hydroxy-4H-1-benzopyran-4-one
(-)-(2S)-7,8-(2,3,3-trimethyl-2,3-dihydrofuran)kaempferide
5,4-dihydroxy-7-methoxy-3-(3-methyl-2-hydroxybuten-3-yl)isoflavone
2-O-(4-Methoxyphenyl)-2,5,7-Trihydroxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
2-beta-D-glucopyranosyl-2-isobutyltartrate
C14H24O11 (368.13185539999995)
18-bromo-(5E,17E)-octadeca-5,17-diene-15-ynoic acid methyl ester|methyl ester of 18-bromo-(5E,17E)-octadeca-5,7-diene-15-ynoic acid
1alpha-chloro-10beta-hydroxy-6beta-(2-methylpropanoyloxy)-9-oxo-7,8-furoeremophilane|1alpha-chloro-6beta-isobutyroxy-9-oxo-10beta-hydroxy-furanoeremophilane|1alpha-chloro-6beta-isobutyryloxy-9-oxo-10beta-hydroxyfuranoeremophilane
3-hydroxy-8,9-methylenedioxy-[2,2-dimethyl-3,4-dihydropyrano-(5,6:1,2)][6aR,11aR]pterocarpan|maackiapterocarpan A
4,5-dihydroxy-6-methoxy-4,4-dimethyl-4,5-dihydro-6H-pyrano[2,3:7,8]-isoflavone
3-(3-Hydroxy-2,4-dimethoxyphenyl)-3,4-dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b]dipyran
(6aR,11aR)-2-(4-hydroxy-1-isopentenyl)-3-hydroxy-8,9-methylenedioxypterocarpan
1,3-Dihydroxy-6,8-dimethoxy-2-isoprenylanthraquinone|6,8-Di-Me ether-1,3,6,8-Tetrahydroxy-2-(3-methyl-2-butenyl)anthaquinone
6-Ac-3-O-alpha-L-Rhamnopyranosyl-D-galactose3-O-alpha-L-Rhamnopyranosyl-D-galactose
C14H24O11 (368.13185539999995)
4-(3,4,8,9-Tetrahydro-8-isopropenyl-5-hydroxy-6-methyl-2H-furo[2,3-h]-1-benzopyran-3-yl)-3-methoxyphenol
(4-Methoxybenzofuran-5-yl)(6,7-dimethoxy-3,4-dihydro-2H-1-benzopyran-4-yl) ketone
(11E)-4,15,12-trimethoxy-2-oxatricyclo[13.2.2.13,7]icosa-1(17),3,5.7(20),11,15,18-heptaen-10-one|garuganin III
butyl 2-[7-hydroxy-2-(4-hydroxyphenyl)-4-oxo-chromen-5-yl]acetate
5-(3,4-Dimethoxyphenyl)naphtho[2,3-d]-1,3-dioxole-6,7-bismethanol
2-(3,4-Dihydroxyphenyl)-5-hydroxy-6,8,8-trimethyl-2H,8H-benzo[1,2-b:3,4-b]dipyran-4(3H)-one
4-hydroxy-6,7-dimethoxy-2,3-dimethyl-4-piperonyltetralin-2-en-1-one
4-Methoxy-2,5,7-trihydroxy-5-(3-methyl-2-butenyl)isoflavone
Sinapinethiocyanate
Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species. Sinapine thiocyanate exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease[1][2][3][4]. Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species. Sinapine thiocyanate exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease[1][2][3][4].
5,7-dihydroxy-3-[3-hydroxy-4-methoxy-5-(3-methylbut-2-enyl)phenyl]chromen-4-one
(1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one
(2S)-8-[(E)-3-hydroxy-3-methylbut-1-enyl]-5,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one
Tricresylphosphate
C21H21O4P (368.11773960000005)
CONFIDENCE standard compound; INTERNAL_ID 2476 CONFIDENCE standard compound; INTERNAL_ID 8832
Dehydroepiandrosterone sulfate
C19H28O5S (368.16573580000005)
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.
(1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one
(1R,2E,8S,10R,11S)-10,11-dihydroxy-6-(methoxymethyl)-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.0³,⁷]tetradeca-2,6-dien-8-yl acetate
(2S)-8-[(E)-3-hydroxy-3-methylbut-1-enyl]-5,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one
(2S)-8-[(E)-3-hydroxy-3-methylbut-1-enyl]-5,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one [IIN-based on: CCMSLIB00000848309]
(2S)-8-[(E)-3-hydroxy-3-methylbut-1-enyl]-5,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one [IIN-based: Match]
(2S)-8-[(E)-3-hydroxy-3-methylbut-1-enyl]-5,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one [IIN-based on: CCMSLIB00000848308]
Dehydroepiandrosterone sulfate; LC-tDDA; CE10
C19H28O5S (368.16573580000005)
Dehydroepiandrosterone sulfate; LC-tDDA; CE20
C19H28O5S (368.16573580000005)
Dehydroepiandrosterone sulfate; LC-tDDA; CE30
C19H28O5S (368.16573580000005)
Dehydroepiandrosterone sulfate; LC-tDDA; CE40
C19H28O5S (368.16573580000005)
(1R,2E,8S,10R,11S)-10,11-dihydroxy-6-(methoxymethyl)-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.0³,⁷]tetradeca-2,6-dien-8-yl acetate_70.7\\%
(1R,2E,8S,10R,11S)-10,11-dihydroxy-6-(methoxymethyl)-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.0³,⁷]tetradeca-2,6-dien-8-yl acetate_major
2-[(E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]oxyethyl-trimethylazanium;thiocyanate_major
(1R,2E,8S,10R,11S)-10,11-dihydroxy-6-(methoxymethyl)-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.0³,?]tetradeca-2,6-dien-8-yl acetate
Testosterone sulfate
C19H28O5S (368.16573580000005)
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D000728 - Androgens A steroid sulfate that is testosterone substituted by a sulfoxy group at position 17.
3-β-hydroxyandrost-5-en-17-one sulfate
C19H28O5S (368.16573580000005)
Artocarpetin A
Cyclocurcumin
mollicellin H
A member of the class of depsidones that is 11H-dibenzo[b,e][1,4]dioxepine substituted by hydroxy groups at position 3 and 7, methyl group at positions 1 and 9, a prenyl group at position 8, an oxo group at position 11 and a formyl group at position 4. Isolated from Chaetomium brasiliense it exhibits cytotoxic activity.
Glycyrrhizaisoflavone C
4-Hydroxy-3-prenylbenzoic acid glucoside
Methyl (R)-9-hydroxy-10-undecene-5,7-diynoate glucoside
Kanzonol P
A member of the class of pterocarpans that is (6aR,11aR)-pterocarpan substituted by a hydroxy group at position 9, methoxy groups at position 1 and 3 and a prenyl group at position 2. It has been isolated from Glycyrrhiza uralensis.
(2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside]
C15H28O10 (368.16823880000004)
Methyl 18-bromo-octadeca-5E,17E-diene-15-ynoate
Methyl 18-bromo-octadeca-5E,17E-diene-15-ynoate
hbas#9
tert-butyl 4-(cyanomethyl)-4-(4-Methylphenyl)piperidine-1-carbox
diethyl 2-(3-oxo-1,3-diphenyl-propyl)propanedioate
Methyl 6-(benzyloxy)-4-hydroxy-5,7-dimethoxy-2-naphthoate
7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-3H-1,4-benzodiazepin-2-one
Benzamide, N-[3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-
N-(2,4-dimethylphenyl)-2-[(4-methyl-2-nitrophenyl)azo]-3-oxobutyramide
C19H20N4O4 (368.14844800000003)
4-(3-CARBAMOYL-BENZENESULFONYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
4-(4-CARBAMOYL-BENZENESULFONYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
N-benzyloxymethyl-5-(2-cyano-pyridin-4-yl)-3-(pyridin-4-yl)-1,2,4-triazole
C21H16N6O (368.13855259999997)
SB 239063
C20H21FN4O2 (368.16484579999997)
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
(DIOXALAN-2-YL-METHYL)-TRIBUTYLPHOSPHONIUM BROMIDE
(s)3-(9h-fluoren-9-ylmethoxycarbonylamino)-succinamic acid methyl ester
3-(3-CARBAMOYL-BENZENESULFONYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
3-(4-CARBAMOYL-BENZENESULFONYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
2-(4-benzhydrylpiperazin-1-yl)ethanol,dihydrochloride
2-[N-ethyl-4-[(4-nitrophenyl)diazenyl]anilino]ethyl prop-2-enoate
C19H20N4O4 (368.14844800000003)
cyc-116
4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester
Thiourea, N-[2-(1H-benzimidazol-2-yl)ethyl]-N-(2-methoxyethyl)-N-(phenylmethyl)- (9CI)
1-[10-[3-[bis(trideuteriomethyl)amino]propyl]phenothiazin-2-yl]ethanone,hydrochloride
C19H17ClD6N2OS (368.159616868)
2-[(2-PHENYL-QUINOLINE-4-CARBONYL)-AMINO]-BENZOIC ACID
(2s,5r)-5-((phenylmethoxy)amino)-2-piperidinecarboxylic acid ethyl ester ethanedioate
4-(6-acryloxyhexyloxy)-[1,1-biphenyl]-4-carboxylic acid
3-[(Aminoiminomethyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine
C19H20N4O4 (368.14844800000003)
16alpha-Bromoepiandrosterone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
N-[(3Z)-5-Tert-butyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-ylidene]-N-(4-chlorophenyl)urea
Flurpiridaz (18F)
C18H22ClFN2O3 (368.13029040000004)
C1446 - Radiopharmaceutical Compound > C2124 - Radioconjugate
Vapitadine dihydrochloride
C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
(2S)-((6-O-(beta-D-apiofuranosyl)beta-D-glucopyranosyl)oxy)butane
C15H28O10 (368.16823880000004)
Benzamide, N-(2-chloro-2-phenyl-1-(1-piperidinylcarbonyl)ethenyl)-
3,5-dichloro-N-[[(1R,5S)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide
2-(3,4-dichlorophenyl)-N-methyl-N-[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]acetamide
Methyl 5-[(3-methyl-6-oxo-7,8,9,10-tetrahydrobenzo[c]chromen-1-yl)oxymethyl]furan-2-carboxylate
1-(9H-carbazol-9-yl)-3-(quinolin-8-yloxy)propan-2-ol
5-Methyl-4-[(3-methyl-6-oxo-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-1-yl)oxymethyl]-2-furancarboxylic acid
N-[4-(4-morpholinyl)phenyl]-2-naphthalenesulfonamide
N-(2-oxolanylmethyl)-2-[7-oxo-3-(phenylmethyl)-6-triazolo[4,5-d]pyrimidinyl]acetamide
2-(2-Phenyl-3-pyridin-2-YL-4,5,6,7-tetrahydro-2H-isophosphindol-1-YL)pyridine
3-Oxoandrost-4-en-17-yl hydrogen sulfate
C19H28O5S (368.16573580000005)
N-[(3R)-6-(5,6-dihydropyridin-2-yl)-7-hydroxy-8-[(2E)-1-hydroxybut-2-en-1-yl]-2-oxo-1,5-oxathiocan-3-yl]acetamide
S-[[1,7-Dioxo-2,5,6-trimethyl-1H,7H-pyrazolo[1,2-a]pyrazole-3-yl]methyl]-L-Cys-Gly-OH
C15H20N4O5S (368.11543500000005)
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(3R,5S)-1-methyl-2-oxo-5-pyridin-3-ylpyrrolidin-3-yl]oxyoxane-2-carboxylic acid
(2R)-2-acetamido-3-[1-(2,3-dihydropyridin-6-yl)-2-hydroxy-2-[3-[(E)-prop-1-enyl]oxiran-2-yl]ethyl]sulfanylpropanoic acid
16,17-Dihydroxyestra-1,3,5(10)-trien-3-yl hydrogen sulfate
[(2R,10R,14S,15S)-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-14-yl]oxidanesulfonic acid
C19H28O5S (368.16573580000005)
trans-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzeneacetamide
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
Maackiapterocarpan A
A member of the class of pterocarpans that is pterocarpan substituted by a hydroxy group at position 3, a methylenedioxy group across positions 8 and 9 and a 2,2-dimethyltetrahydro-2H-pyran ring fused across positions 1 and 2 (the 8aR,14aR stereoisomer). Isolated from the stem barks of Maackia amurensis,it exhibits cytotoxicity against human cancer cell lines.
N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-methylbenzenesulfonohydrazide
7-(trimethylsilyl)-2,6-bis[(trimethylsilyl)oxy]-7H-purine
N-(2-furanylmethyl)-5-(4-morpholinyl)-4-phenyl-2-thiophenecarboxamide
N-(3-methoxyphenyl)-2-(3-methoxypropyl)-1,3-dioxo-5-isoindolecarboxamide
1,3-bis(butylsulfonyl)-3a,4,6,6a-tetrahydro-2H-imidazo[4,5-d]imidazol-5-one
N-[4-[(2,3-dihydro-1,4-benzodioxin-6-ylamino)-oxomethyl]phenyl]-2-oxolanecarboxamide
(1E,6E)-1-(3-hydroxy-2-methoxyphenyl)-7-(3-hydroxy-4-methoxyphenyl)hepta-1,6-diene-3,5-dione
2-(4-chlorophenyl)-N-[2-(4-morpholinyl)ethyl]-4-quinazolinamine
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(2-methoxyethyl)-3-oxo-1H-isoindole-4-carboxamide
N-[4-(phenoxymethyl)-2-thiazolyl]-1-adamantanecarboxamide
6-[[(2-chlorophenyl)methyl-methylamino]methyl]-N2-(2-methylphenyl)-1,3,5-triazine-2,4-diamine
1-methoxy-N-[4-(pyridin-4-ylmethyl)phenyl]-2-naphthalenecarboxamide
8-(2-fluorobenzylidene)-4-(2-fluorophenyl)-3,4,5,6,7,8-hexahydro-2(1H)-quinazolinethione
C21H18F2N2S (368.11586919999996)
1-[2-(3-Chloro-phenyl)-6,7-dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidin-8-yl]-piperidin-3-ol
N-butan-2-yl-4-[4-oxo-3-(phenylmethyl)-2-thiazolidinyl]benzamide
2-(4-Phenethyl-5-phenoxymethyl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide
2-[[4-(1-Pyrrolidinyl)-6-[2-(trifluoromethyl)anilino]-1,3,5-triazin-2-yl]amino]ethanol
C16H19F3N6O (368.15723599999995)
5-methyl-4-(3-phenoxyphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-6-carboxylic acid ethyl ester
N-(2-furanylmethyl)-N-methyl-6-(1-methyl-5-indolyl)-4-quinazolinamine
N-[3,5-dicyano-1-(4-methylphenyl)-6-oxo-4-phenyl-2-pyridinyl]acetamide
C22H16N4O2 (368.12731959999996)
3-ethyl-6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-1H-pyrimidine-2,4-dione
C17H19F3N4O2 (368.14600299999995)
(2S,3R,4S)-4-(hydroxymethyl)-1-methylsulfonyl-3-[4-[(E)-2-phenylethenyl]phenyl]azetidine-2-carbonitrile
N-[(2S,3R,6S)-6-[2-[(3,5-difluorophenyl)methylamino]-2-oxoethyl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl]propanamide
C18H22F2N2O4 (368.15475560000004)
N-[(2S,3S,6R)-6-[2-[(3,5-difluorophenyl)methylamino]-2-oxoethyl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl]propanamide
C18H22F2N2O4 (368.15475560000004)
1-[(1R,2aS,8bS)-2-[cyclopropyl(oxo)methyl]-1-(hydroxymethyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-3,3,3-trifluoro-1-propanone
1-[(1R,2aR,8bR)-2-[cyclopropyl(oxo)methyl]-1-(hydroxymethyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-3,3,3-trifluoro-1-propanone
N-[(2R,3R,6R)-6-[2-[(3,5-difluorophenyl)methylamino]-2-oxoethyl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl]propanamide
C18H22F2N2O4 (368.15475560000004)
N-[(2S,3R,6R)-6-[2-[(3,5-difluorophenyl)methylamino]-2-oxoethyl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl]propanamide
C18H22F2N2O4 (368.15475560000004)
N-[(2R,3S,6S)-6-[2-[(3,5-difluorophenyl)methylamino]-2-oxoethyl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl]propanamide
C18H22F2N2O4 (368.15475560000004)
N-[(2R,3S,6R)-6-[2-[(3,5-difluorophenyl)methylamino]-2-oxoethyl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl]propanamide
C18H22F2N2O4 (368.15475560000004)
N-[(2R,3R,6S)-6-[2-[(3,5-difluorophenyl)methylamino]-2-oxoethyl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl]propanamide
C18H22F2N2O4 (368.15475560000004)
N-[(2S,3S,6S)-6-[2-[(3,5-difluorophenyl)methylamino]-2-oxoethyl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl]propanamide
C18H22F2N2O4 (368.15475560000004)
1-[(1S,2aS,8bS)-2-[cyclopropyl(oxo)methyl]-1-(hydroxymethyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-3,3,3-trifluoro-1-propanone
1-[(1S,2aR,8bR)-2-[cyclopropyl(oxo)methyl]-1-(hydroxymethyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-3,3,3-trifluoro-1-propanone
(1S,5R)-3-(4-methylphenyl)sulfonyl-7-[4-[(E)-prop-1-enyl]phenyl]-3,6-diazabicyclo[3.1.1]heptane
2,17beta-Dihydroxyestra-1,3,5(10)-trien-3-yl hydrogen sulfate
3,4,5-Trihydroxy-6-[4-(4-methyl-3-oxopentyl)phenoxy]oxane-2-carboxylic acid
methyl 2-[[3-cyano-4-(4-methylphenyl)-5-oxo-4a,6,7,8-tetrahydro-4H-quinolin-2-yl]sulfanyl]acetate
[(1R,2E,8S,10S,11S)-10,11-dihydroxy-6-(methoxymethyl)-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-2,6-dien-8-yl] acetate
(1-Pentanoyloxy-3-phosphonooxypropan-2-yl) heptanoate
(1-Butanoyloxy-3-phosphonooxypropan-2-yl) octanoate
(1-Phosphonooxy-3-propanoyloxypropan-2-yl) nonanoate
2,6-dimethoxy-4-[(E)-3-oxo-3-[2-(trimethylazaniumyl)ethoxy]prop-1-enyl]phenolate;thiocyanic acid
9-Hydroxy-4-(3,7-dimethyl-2,6-octadienyloxy)-psoralen
U50488
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
1-(3-hydroxy-2-methoxyphenyl)-7-(3-hydroxy-4-methoxyphenyl)hepta-1,6-diene-3,5-dione
1,2-dihexanoyl-sn-glycero-3-phosphate
A 1,2-diacyl-sn-glycero-3-phosphate in which the acyl groups at positions 1 and 2 are specified as hexanoyl.
trans-3-hydroxycotinine beta-D-glucuronide
A beta-D-glucosiduronic acid that is trans-3-hydroxycotinine in which the hydroxy hydrogen is replaced by a beta-D-glucuronyl residue.
8-(1,1-Dimethylallyl)kaempferide
A 7-hydroxyflavonol that is kaempferide substituted by a 1,1-dimethylallyl group at position 8.
4-(2-fluorophenyl)-8-[(2-fluorophenyl)methylidene]-1,3,4,5,6,7-hexahydroquinazoline-2-thione
C21H18F2N2S (368.11586919999996)
BisMePA(10:0)
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LJI308
C21H18F2N2O2 (368.1336271999999)
LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation[1][2].
MRK-016
MRK-016 is a selective, orally bioavailable inverse agonist of GABAA α5 receptor, with an EC50 of 3 nM for GABAA α5, and Kis of 0.83, 0.85, 0.77?and 1.4?nM for human?GABAA?α1β3γ2, GABAA?α2β3γ2, GABAA?α3β3γ2, and GABAA?α5β3γ2, respectively; MRK-016 also readily penetrates the CNS.