Exact Mass: 179.0807
Exact Mass Matches: 179.0807
Found 500 metabolites which its exact mass value is equals to given mass value 179.0807,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Glucosamine
Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of two polysaccharides, chitosan and chitin. Glucosamine is one of the most abundant monosaccharides. Produced commercially by the hydrolysis of shellfish exoskeletons or, less commonly, by fermentation of a grain such as corn or wheat, glucosamine has many names depending on country. Although a common dietary supplement, there is little evidence that it is effective for relief of arthritis or pain, and is not an approved prescription drug. In the United States, glucosamine is not approved by the Food and Drug Administration for medical use in humans. Since glucosamine is classified as a dietary supplement, evidence of safety and efficacy is not required as long as it is not advertised as a treatment for a medical condition. Nevertheless, glucosamine is a popular alternative medicine used by consumers for the treatment of osteoarthritis. Glucosamine is also extensively used in veterinary medicine as an unregulated but widely accepted supplement. Treatment with oral glucosamine is commonly used for the treatment of osteoarthritis. Since glucosamine is a precursor for glycosaminoglycans, and glycosaminoglycans are a major component of joint cartilage, supplemental glucosamine may help to rebuild cartilage and treat arthritis. However, there is little evidence that any clinical effect of glucosamine works this way. Its use as a therapy for osteoarthritis appears safe but there is conflicting evidence as to its effectiveness. Glucosamine is naturally present in the shells of shellfish, animal bones, bone marrow, and fungi. D-Glucosamine is made naturally in the form of glucosamine-6-phosphate, and is the biochemical precursor of all nitrogen-containing sugars. Specifically in humans, glucosamine-6-phosphate is synthesized from fructose 6-phosphate and glutamine by glutamine—fructose-6-phosphate transaminase as the first step of the hexosamine biosynthesis pathway. The end-product of this pathway is uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. As the formation of glucosamine-6-phosphate is the first step for the synthesis of these products, glucosamine may be important in regulating their production; however, the way that the hexosamine biosynthesis pathway is actually regulated, and whether this could be involved in contributing to human disease remains unclear. Present in mucopolysaccharides and in polysaccharides found in bacteria, fungi, higher plants, invertebrates, vertebrates, antibiotics and UDP complexes. Obt. comly. by hydrol. of seashells [CCD] M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID G051 Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
Nojirimycin
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents D004791 - Enzyme Inhibitors
Acetylisoniazid
Acetylisoniazid belongs to the family of Pyridinecarboxamides. These are compounds containing a pyridine ring bearing a carboxamide.
7-Aminomethyl-7-carbaguanine
7-Aminomethyl-7-carbaguanine is one of the precursors of nucleoside Q (queuosine) biosynthesis. It is a substrate for preQ1 synthase (EC 1.7.1.13) which catalyzes the NADPH-dependent reduction of 7-cyano-7-carbaguanine (preQ0) to 7-aminomethyl-7-carbaguanine (preQ1). More specifically, this enzyme catalyzes the chemical reaction. 7-aminomethyl-7-carbaguanine + 2 NADP+ <-> 7-cyano-7-carbaguanine + 2 NADPH + 2 H+. 7-Aminomethyl-7-carbaguanine is one of the precursors of nucleoside Q (queuosine) biosynthesis. It is a substrate for preQ1 synthase (EC 1.7.1.13) which catalyzes the NADPH-dependent reduction of 7-cyano-7-carbaguanine (preQ0) to 7-aminomethyl-7-carbaguanine (preQ1). More specifically, this enzyme catalyzes the chemical reaction
beta-D-Glucosamine
Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of the polysaccharides chitosan and chitin, which compose the exoskeletons of crustaceans and other arthropods, cell walls in fungi and many higher organisms. In the US it is one of the most common non-vitamin, non-mineral, dietary supplements used by adults. beta-D-Glucosamine is found in common bean, yellow wax bean, and green bean. beta-D-Glucosamine is found in common bean. Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of the polysaccharides chitosan and chitin, which compose the exoskeletons of crustaceans and other arthropods, cell walls in fungi and many higher organisms. In the US it is one of the most common non-vitamin, non-mineral, dietary supplements used by adults. (Wikipedia
Galactosamine
Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID G046
Fructosamine
Fructosamine is a compound which can be considered as the result of a reaction between fructose and ammonia or an amine (with a molecule of water being released). A fructosamine is also formed when carbonyl group of glucose reacts with an amino group of a protein, as the double bond to oxygen moves from the end carbon atom to the next carbon atom and water is released. Fructosamines formed from blood proteins such as serum albumin are known as Glycated Serum Protein (GSP) or Glycated Albumin, and are used to identify the plasma glucose concentration over time and so assess diabetic control (wikipedia). Glucose molecules are joined to protein molecules to form stable ketoamines, or fructosamines, through glycation, a nonenzymatic mechanism involving a labile Schiff base intermediate and the Amadori rearrangement. The amount of fructosamine in serum is increased in diabetes mellitus owing to the abnormally high concentration of sugar in blood. The concentration of fructosamine in serum thus reflects the degree of glycemic control attained by the diabetic patient and is useful in monitoring the effectiveness of therapy in diabetes over a period of several weeks, in a manner analogous to the determination of glycated hemoglobin. Of the analytical approaches used to measure fructosamine, affinity chromatography with m-aminophenylboronic acid and the nitroblue tetrazolium reduction method appear to be the most practical means for clinical chemists to assay fructosamine quickly, economically, and accurately. Fructosamine values can readily distinguish normal individuals and diabetic patients in good glycemic control from diabetics in poor control. Unlike glycated hemoglobin, which reflects the average blood sugar concentration over the past six to eight weeks, fructosamine reflects the average blood sugar concentration over the past two to three weeks. Thus a clinical advantage is that fructosamine responds more quickly to changes in therapy, thereby allowing for improved glycemic control. Fructosamine is used in conjunction with determinations of blood sugar and (or) of glycated hemoglobin, or by itself, the fructosamine assay can provide clinically useful information for the detection and control of diabetes (PMID: 3319287). Fructosamine is found to be associated with 11-beta-hydroxylase deficiency, which is an inborn error of metabolism. Fructosamine is a compound which can be considered as the result of a reaction between fructose and ammonia or an amine (with a molecule of water being released). A fructosamine is also formed when carbonyl group of glucose reacts with an amino group of a protein, as the double bond to oxygen moves from the end carbon atom to the next carbon atom and water is released. Fructosamines formed from blood proteins such as serum albumin are known as Glycated Serum Protein (GSP) or Glycated Albumin, and are used to identify the plasma glucose concentration over time and so assess diabetic control. (wikipedia)
azaphenanthrene
CONFIDENCE standard compound; INTERNAL_ID 522; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7038; ORIGINAL_PRECURSOR_SCAN_NO 7036 CONFIDENCE standard compound; INTERNAL_ID 522; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7078; ORIGINAL_PRECURSOR_SCAN_NO 7076 CONFIDENCE standard compound; INTERNAL_ID 522; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7088; ORIGINAL_PRECURSOR_SCAN_NO 7086 CONFIDENCE standard compound; INTERNAL_ID 522; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7110; ORIGINAL_PRECURSOR_SCAN_NO 7108 CONFIDENCE standard compound; INTERNAL_ID 522; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7117; ORIGINAL_PRECURSOR_SCAN_NO 7116 CONFIDENCE standard compound; INTERNAL_ID 522; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7120; ORIGINAL_PRECURSOR_SCAN_NO 7117
Stachydrine
Stachydrine hydrochloride is the major active constituent of Leonurus artemisia, which is a potential therapy for cardiovascular diseases[2]. Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities[1]. Stachydrine hydrochloride is the major active constituent of Leonurus artemisia, which is a potential therapy for cardiovascular diseases[2]. Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities[1].
Tenamfetamine
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D006213 - Hallucinogens C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents D049990 - Membrane Transport Modulators CONFIDENCE standard compound; EAWAG_UCHEM_ID 3715
Salsolinol
Salsolinol is an endogenous catechol isoquinoline detected in humans. Salsolinol was detected in urine of parkinsonian patients administered with L-DOPA. This finding stimulated the studies on Salsolinol derivatives in the brain, and gave new aspects of the endogenous alkaloids, which had been considered to occur only in plants. In normal non-alcoholic subjects and alcoholics, Salsolinol and O-methylated Salsolinol were found in urine, cerebrospinal fluid and brains. Salsolinol has an asymmetric center at first position and exists as (R)- and (S)enantiomer. The (R)enantiomer of Salsolinol is predominant in urine from healthy volunteers. Only the (R)enantiomers of Salsolinol and N-methylated Salsolinol occur in the human brain, cerebrospinal fluid (CSF) and intraventricular fluid (IVF), and the (S)enantiomers were not detected. (R)salsolinol synthase catalyzes the enantio-selective synthesis of (R)Salsolinol and 1-carboxyl(R)Salsolinol from dopamine with acetaldehyde or pyruvic acid. The N-methylation of (R)salsolinol into N-methylsalsolinol (NMSal) is catalyzed by two N-methyltransferases with different optimum pH, at pH 7.0 and 8.4. NM(R)Salsolinol is enzymatically oxidized into 1,2-dimethyl-6,7-dihydroxyisoquinolinium ion (DMDHIQ+) by an oxidase sensitive to semicarbaside and also non-enzymatically by autoxidation. NM(R)Salsolinol and its precursor, dopamine, were found to occur selectively in the nigro-striatum, whereas (R)Salsolinol distributes uniformly among the brain regions. (PMID 14697894) [HMDB]. Acquisition and generation of the data is financially supported by the Max-Planck-Society IPB_RECORD: 1521; CONFIDENCE confident structure
L-beta-Homophenylalanine
Acquisition and generation of the data is financially supported in part by CREST/JST.
fusaric acid
D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents CONFIDENCE Fusarium verticilloides relative retention time with respect to 9-anthracene Carboxylic Acid is 0.535 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.533 Fusaric acid is a potent dopamine β-hydroxylase inhibitor.
phenacetin
N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BE - Anilides D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
Glucosamine
Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
LID_180.1018_12.9
CONFIDENCE Tentative identification: most likely structure (Level 3); INTERNAL_ID 805
D-Glucosamine
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
1,2,3,4,5,6-hexahydro-5-(1-Hydroxyethylidene)-7H-1-pyrindin-7-one, 12ci
2,3-Dihydro-5-(3-hydroxypropanoyl)-1H-pyrrolizine
methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride
1(2H)-QUINOLINECARBOXALDEHYDE, 6-FLUORO-3,4-DIHYDRO-
cis-2-amino-2-methylcyclopentanecarboxylic acid hydrochloride
Methyl cis-2-Aminocyclopentanecarboxylate Hydrochloride
trans-4-Aminocyclohexanecarboxylic acid hydrochloride
b-D-Galactopyranosyl amine
1,3-Dimethyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione
1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE
1-Amino-cyclobutanecarboxylic acid ethyl ester hydrochloride
2-amino-5,6-dimethyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
1-methylpiperidine-3-carboxylic acid hydrochloride
Methyl 1-aminocyclopentanecarboxylate hydrochloride
Hydrazinecarboxamide,2-[(2-hydroxyphenyl)methylene]-
1-methylpiperidine-2-carboxylic acid hydrochloride
(R)-Methyl 2-(pyrrolidin-2-yl)acetate hydrochloride
BENZOIC ACID, 5-METHYL-2-(METHYLAMINO)-, METHYL ESTER
3-(1-METHYL-1H-PYRROL-2-YL)-ACRYLIC ACID ETHYL ESTER
(S)-2-AMINO-3-(DIMETHYLAMINO)PROPANOICACIDDIHYDROCHLORIDEMONOHYDRATE
trans-3-Aminocyclohexanecarboxylic acid hydrochloride
Methyl 2-methylpyrrolidine-2-carboxylate hydrochloride
(S)-ETHYL5-(1-(BOC-AMINO)-2-PHENYLETHYL)OXAZOLE-4-CARBOXYLATE
(1S)-4,5-DIMETHOXY-1-(METHYLAMINOMETHYL)-BENZOCYCLOBUTANEHCL
3-Pyrrolidineacetic acid, Methyl ester, hydrochloride, (3R)-
3-Pyrrolidineacetic acid, Methyl ester, hydrochloride, (3S)-
(2,3-Dihydro-1,4-Benzodioxin-6-Ylmethyl)(Methyl)Amine
2-(HYDROXYAMINO)-2-METHYLCYCLOHEXAN-1-ONE HYDROCHLORIDE
trans-3-Aminocyclobutanecarboxylic acid ethyl ester hydrochloride
4-METHYL-4-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
Pyrrolo[2,1-f][1,2,4]triazin-4(1H)-one, 6-(hydroxymethyl)-5-methyl- (9CI)
(S)-1-METHYLPIPERIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE
2-(1,4-Dioxaspiro[4.5]decan-8-ylidene)acetonitrile
1-ISOPROPYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBONITRILE
1-(BENZO[D][1,3]DIOXOL-5-YL)-N,N-DIMETHYLMETHANAMINE
1-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-5-YL)-N-METHYLMETHANAMINE
(S)-Pyrrolidine-2-carboxylic acid ethyl ester hydrochloride
(3R)-3,4-Dihydro-5-methoxy-2H-1-benzopyran-3-amine
1-cyclopropyl-2,5-dimethylpyrrole-3-carboxylic acid
(S)-2,3-DIHYDRO-N-METHYL-N-2-PROPYNYL-1H-INDEN-1-AMINE
(2E)-3-Carboxy-N,N,N-trimethyl-2-propen-1-aminium chloride
Cis Methyl 3-aMinocyclopentanecarboxylate hydrochloride
2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID ETHYL ESTER
METHYL 1-(AMINOMETHYL)CYCLOBUTANECARBOXYLATE HYDROCHLORIDE
CIS-3-AMINOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE
(5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol
4,4-Dimethylpyrrolidine-3-carboxylic acid hydrochloride
(1R,2S)-(-)-2-Aminocyclohexanecarboxylic acid hydrochloride
1-aminocyclohexane-1-carboxylic acid,hydrochloride
Ethyl 1-(aminomethyl)cyclopropanecarboxylate hydrochloride
Methyl 3-aminocyclopentanecarboxylate hydrochloride
alpha-d-Galactosamine
A 2-amino-2-deoxy-D-galactopyranose that has alpha- configuration at the anomeric centre.
6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-methyl-, (R)-
1,3-Dimethyl-1h-pyrrolo[2,3-d]pyrimidine-2,4(3h,7h)-dione
(2S,3R,4S,5S,6S)-5-amino-6-(hydroxymethyl)oxane-2,3,4-triol
{[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]ammonio}acetate
N-Methyl-L-phenylalanine
A phenylalanine derivative consisting of L-phenylalanine having a methyl substuent attached to the alpha-amino function.
5-(1-hydroxyethylidene)-hexahydro-7H-cyclopenta[b]pyridin-7-one
beta-D-Glucosamine
A 2-amino-2-deoxy-D-glucopyranose that is D-glucosamine having a beta-configuration at the anomeric position.
alpha-D-glucosamine
A 2-amino-2-deoxy-D-glucopyranose with an alpha-configuration at the anomeric position.
2-amino-2-deoxy-beta-D-galactopyranose
A deoxygalactose derivative that is beta-D-galactose in which the hydroxy group at position 2 has been replaced by an amino group.
2-amino-2-deoxy-D-galactopyranose
The pyranose form of D-galactosamine.
2-Amino-2-deoxy-D-glucopyranose
A D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2.
N-acetylisoniazid
A carbohydrazide resulting from the formal condensation of the carboxy group of isonicotinic acid with hydrazine and subsequent acetylation of the monosubstituted nitrogen atom.
