Galactosamine (BioDeep_00000015278)
Secondary id: BioDeep_00001868679
natural product BioNovoGene_Lab2019
代谢物信息卡片
化学式: C6H13NO5 (179.0793688)
中文名称: 半乳糖胺
谱图信息:
最多检出来源 Chinese Herbal Medicine(natural_products) 2.17%
分子结构信息
SMILES: C(=O)[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)N
InChI: InChI=1S/C6H13NO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1,7H2
描述信息
Acquisition and generation of the data is financially supported in part by CREST/JST.
KEIO_ID G046
同义名列表
数据库引用编号
42 个数据库交叉引用编号
- ChEBI: CHEBI:24156
- ChEBI: CHEBI:60312
- KEGG: C02262
- PubChem: 24154
- Metlin: METLIN63181
- ChEMBL: CHEMBL3304228
- MeSH: Galactosamine
- CAS: 7535-00-4
- CAS: 90-76-6
- MoNA: CCMSLIB00005464146
- MoNA: CCMSLIB00005464147
- MoNA: CCMSLIB00005464148
- MoNA: CCMSLIB00005464149
- MoNA: MoNA038616
- MoNA: MoNA037245
- MoNA: MoNA036216
- MoNA: MoNA036213
- MoNA: MoNA036212
- MoNA: MoNA032311
- MoNA: MoNA032310
- MoNA: MoNA032309
- MoNA: MoNA024028
- MoNA: FiehnHILIC000371
- MoNA: KO002985
- MoNA: KO002987
- MoNA: KO002986
- MoNA: PR100044
- MoNA: PR100043
- MoNA: KO002988
- MoNA: KO002984
- MoNA: PS007403
- MoNA: PS007402
- MoNA: PS007401
- ChEBI: CHEBI:177035
- PubChem: 5324
- PDB-CCD: 1GN
- PDB-CCD: X6X
- 3DMET: B04845
- NIKKAJI: J16.141A
- RefMet: Galactosamine
- LOTUS: LTS0099079
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-366
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- galactosamine degradation:
D-galactosamine + H+ ⟶ D-galactosamine 6-phosphate + a [protein]-L-histidine
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
10 个相关的物种来源信息
- 3481 - Cannabaceae: LTS0099079
- 3482 - Cannabis: LTS0099079
- 3483 - Cannabis sativa: 10.1021/NP50008A001
- 3483 - Cannabis sativa: LTS0099079
- 2759 - Eukaryota: LTS0099079
- 3398 - Magnoliopsida: LTS0099079
- 35493 - Streptophyta: LTS0099079
- 58023 - Tracheophyta: LTS0099079
- 33090 - Viridiplantae: LTS0099079
- 29760 - Vitis vinifera: 10.1016/J.DIB.2020.106469
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yuqiao Zeng, Yiyu He, Li Wang, Hao Xu, Qianwen Zhang, Yanjun Wang, Jianhua Zhang, Likun Wang. Dihydroquercetin improves experimental acute liver failure by targeting ferroptosis and mitochondria-mediated apoptosis through the SIRT1/p53 axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jun; 128(?):155533. doi:
10.1016/j.phymed.2024.155533
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International immunopharmacology.
2024 Mar; 130(?):111732. doi:
10.1016/j.intimp.2024.111732
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Chemical & pharmaceutical bulletin.
2024 Mar; 72(3):280-285. doi:
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Journal of ethnopharmacology.
2023 Sep; 313(?):116589. doi:
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Physiological research.
2023 Aug; 72(4):445-454. doi:
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Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2023 Jun; 268(?):109603. doi:
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Biological & pharmaceutical bulletin.
2023; 46(6):848-855. doi:
10.1248/bpb.b23-00167
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Planta medica.
2022 Dec; ?(?):. doi:
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Journal of biochemical and molecular toxicology.
2022 Oct; 36(10):e23168. doi:
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Journal of biochemical and molecular toxicology.
2022 Sep; 36(9):e23124. doi:
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Food & function.
2022 Aug; 13(16):8593-8604. doi:
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Amino acids.
2022 Jul; 54(7):1069-1081. doi:
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Acta biomaterialia.
2022 Jul; 146(?):385-395. doi:
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Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.
2022 Apr; 30(4):413-418. doi:
10.3760/cma.j.cn501113-20201204-00639
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Frontiers in immunology.
2022; 13(?):971409. doi:
10.3389/fimmu.2022.971409
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Pakistan journal of biological sciences : PJBS.
2022 Jan; 25(3):191-200. doi:
10.3923/pjbs.2022.191.200
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Drug design, development and therapy.
2022; 16(?):3327-3342. doi:
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. [PMID: 36199629] - Sha Huang, Yuhua Wang, Shuwen Xie, Yuqi Lai, Chan Mo, Ting Zeng, Shanshan Kuang, Guanghui Deng, Chuying Zhou, Yuyao Chen, Shaohui Huang, Lei Gao, Zhiping Lv. Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Inhibiting GSK3β-Nrf2-Mediated Hepatocyte Apoptosis and Ferroptosis.
Cellular and molecular gastroenterology and hepatology.
2022; 13(6):1649-1672. doi:
10.1016/j.jcmgh.2022.02.009
. [PMID: 35202887] - Xiao-Jiao He, Bin Xie, Song Huang, Ming-Hua Liu. [Dexmedetomidine alleviates LPS/D-Gal-induced acute liver injury via up-regulation of LC3-II expression in mice].
Sheng li xue bao : [Acta physiologica Sinica].
2021 Dec; 73(6):901-908. doi:
NULL
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Nutrients.
2021 Nov; 13(11):. doi:
10.3390/nu13114090
. [PMID: 34836346] - Aoxiang Zhuge, Shengjie Li, Yin Yuan, Bo Li, Lanjuan Li. The synergy of dietary supplements Lactobacillus salivarius LI01 and Bifidobacterium longum TC01 in alleviating liver failure in rats treated with D-galactosamine.
Food & function.
2021 Oct; 12(20):10239-10252. doi:
10.1039/d1fo01807h
. [PMID: 34546256] - Seyed-Mahdi Mohamadi-Zarch, Tourandokht Baluchnejadmojarad, Davood Nourabadi, Samira Ramazi, Morteza Nazari-Serenjeh, Mehrdad Roghani. Esculetin Alleviates Acute Liver Failure following Lipopolysaccharide/D-Galactosamine in Male C57BL/6 Mice.
Iranian journal of medical sciences.
2021 09; 46(5):373-382. doi:
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. [PMID: 34539012] - Tamás Fekete, Mária Mészáros, Zsolt Szegletes, Gaszton Vizsnyiczai, László Zimányi, Mária A Deli, Szilvia Veszelka, Lóránd Kelemen. Optically Manipulated Microtools to Measure Adhesion of the Nanoparticle-Targeting Ligand Glutathione to Brain Endothelial Cells.
ACS applied materials & interfaces.
2021 Aug; 13(33):39018-39029. doi:
10.1021/acsami.1c08454
. [PMID: 34397215] - Yun Hee Jeong, Youn-Hwan Hwang, Tae In Kim, You-Chang Oh, Jin Yeul Ma. Forsythia Fruit Prevents Fulminant Hepatitis in Mice and Ameliorates Inflammation in Murine Macrophages.
Nutrients.
2021 Aug; 13(8):. doi:
10.3390/nu13082901
. [PMID: 34445058] - Qingbin Zhang, Mengxin Qian, Yong Wu, Yapeng Wang, Wenwen Shangguan, Jianguang Lu, Wenjie Zhao, Jun Feng. Design and biological evaluation of novel long-acting adalimumab Fab conjugated with the albumin binding domain.
European journal of pharmacology.
2021 Aug; 904(?):174152. doi:
10.1016/j.ejphar.2021.174152
. [PMID: 33964292] - Shumin Yue, Tian Wang, Yunqi Yang, Yiqian Fan, Lin Zhou, Mingan Li, Fenghua Fu. Lipopolysaccharide/D-galactosamine-induced acute liver injury could be attenuated by dopamine receptor agonist rotigotine via regulating NF-κB signaling pathway.
International immunopharmacology.
2021 Jul; 96(?):107798. doi:
10.1016/j.intimp.2021.107798
. [PMID: 34162160] - L S Pan, M Y Hua, S Y Xu, Y P Han, D X Luo, Y L Zeng. [Protective effect of vitamin D in mice with acute liver failure].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.
2021 Jun; 29(6):545-550. doi:
10.3760/cma.j.cn501113-20200701-00360
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Cell reports.
2021 06; 35(11):109247. doi:
10.1016/j.celrep.2021.109247
. [PMID: 34133919] - Tingxu Yan, Fuyuan Li, Weilin Xiong, Bo Wu, Feng Xiao, Bosai He, Ying Jia. Nootkatone improves anxiety- and depression-like behavior by targeting hyperammonemia-induced oxidative stress in D-galactosamine model of liver injury.
Environmental toxicology.
2021 Apr; 36(4):694-706. doi:
10.1002/tox.23073
. [PMID: 33270352] - Sawsan M El-Sonbaty, Fatma S M Moawed, Mustafa M M Elbakry. Amphora algae with low-level ionizing radiation exposure ameliorate D-galactosamine-induced inflammatory impairment in rat kidney.
Environmental toxicology.
2021 Apr; 36(4):451-459. doi:
10.1002/tox.23050
. [PMID: 33107697] - Haiyan Wang, Xuehui Li, Guanjun Dong, Fenglian Yan, Junfeng Zhang, Hui Shi, Zhaochen Ning, Min Gao, Dalei Cheng, Qun Ma, Changying Wang, Mingsheng Zhao, Jun Dai, Chunxia Li, Zhihua Li, Hui Zhang, Huabao Xiong. Toll-like Receptor 4 Inhibitor TAK-242 Improves Fulminant Hepatitis by Regulating Accumulation of Myeloid-Derived Suppressor Cell.
Inflammation.
2021 Apr; 44(2):671-681. doi:
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Aging.
2021 03; 13(5):6592-6605. doi:
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. [PMID: 33707345] - Hongyan Li, Tianrong Lei, Jianghua Zhang, Yuhui Yan, Nan Wang, Cheng Song, Chang Li, Mingyu Sun, Jinyu Li, Yuxin Guo, Jingxian Yang, Tingguo Kang. Longan (Dimocarpus longan Lour.) Aril ameliorates cognitive impairment in AD mice induced by combination of D-gal/AlCl3 and an irregular diet via RAS/MEK/ERK signaling pathway.
Journal of ethnopharmacology.
2021 Mar; 267(?):113612. doi:
10.1016/j.jep.2020.113612
. [PMID: 33249246] - Hua Nie, Bo Qiu, Qi-Xuan Yang, Ying Zhao, Xiao-Min Liu, Ying-Ting Zhang, Fu-Lin Liao, Sheng-Yuan Zhang. Effect of gal/GalNAc regioisomerism in galactosylated liposomes on asialoglycoprotein receptor-mediated hepatocyte-selective targeting in vivo.
Journal of liposome research.
2021 Mar; 31(1):79-89. doi:
10.1080/08982104.2019.1682606
. [PMID: 31691619] - Mushtaq Ahmad Ansari, Mohammad Raish, Yousef A Bin Jardan, Ajaz Ahmad, Mudassar Shahid, Sheikh Fayaz Ahmad, Nazrul Haq, Mohammad Rashid Khan, Saleh A Bakheet. Sinapic acid ameliorates D-galactosamine/lipopolysaccharide-induced fulminant hepatitis in rats: Role of nuclear factor erythroid-related factor 2/heme oxygenase-1 pathways.
World journal of gastroenterology.
2021 Feb; 27(7):592-608. doi:
10.3748/wjg.v27.i7.592
. [PMID: 33642831] - Siyu Sun, Xiyou Du, Manfei Fu, Abdur Rauf Khan, Jianbo Ji, Weidong Liu, Guangxi Zhai. Galactosamine-modified PEG-PLA/TPGS micelles for the oral delivery of curcumin.
International journal of pharmaceutics.
2021 Feb; 595(?):120227. doi:
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. [PMID: 33484915] - Yangliu Xia, Ping Wang, Nana Yan, Frank J Gonzalez, Tingting Yan. Withaferin A alleviates fulminant hepatitis by targeting macrophage and NLRP3.
Cell death & disease.
2021 02; 12(2):174. doi:
10.1038/s41419-020-03243-w
. [PMID: 33574236] - Samrat Rakshit, Piyush Shukla, Anjani Verma, Satendra Kumar Nirala, Monika Bhadauria. Protective role of rutin against combined exposure to lipopolysaccharide and D-galactosamine-induced dysfunctions in liver, kidney, and brain: Hematological, biochemical, and histological evidences.
Journal of food biochemistry.
2021 02; 45(2):e13605. doi:
10.1111/jfbc.13605
. [PMID: 33433008] - Yongmei Liu, Linda Fan, Zhuo Cheng, Lei Yu, Shuo Cong, Yaxin Hu, Lili Zhu, Baofang Zhang, Yiju Cheng, Peiling Zhao, Xueke Zhao, Mingliang Cheng. Fecal transplantation alleviates acute liver injury in mice through regulating Treg/Th17 cytokines balance.
Scientific reports.
2021 01; 11(1):1611. doi:
10.1038/s41598-021-81263-y
. [PMID: 33452411] - Ting Xiao, Yulong Cui, Heyu Ji, Lulu Yan, Dongjie Pei, Shuangquan Qu. Baicalein attenuates acute liver injury by blocking NLRP3 inflammasome.
Biochemical and biophysical research communications.
2021 01; 534(?):212-218. doi:
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. [PMID: 33272570] - Ruidong Li, Wenchang Yang, Yuping Yin, Peng Zhang, Yaxin Wang, Kaixiong Tao. Protective Role of 4-Octyl Itaconate in Murine LPS/D-GalN-Induced Acute Liver Failure via Inhibiting Inflammation, Oxidative Stress, and Apoptosis.
Oxidative medicine and cellular longevity.
2021; 2021(?):9932099. doi:
10.1155/2021/9932099
. [PMID: 34457120] - Fang Jia, Fuxue Deng, Pan Xu, Shiying Li, Xuefu Wang, Peng Hu, Hong Ren, Shiwen Tong, Wenwei Yin. NOD1 Agonist Protects Against Lipopolysaccharide and D-Galactosamine-Induced Fatal Hepatitis Through the Upregulation of A20 Expression in Hepatocytes.
Frontiers in immunology.
2021; 12(?):603192. doi:
10.3389/fimmu.2021.603192
. [PMID: 33746949] - Huiyong Jiang, Ren Yan, Kaicen Wang, Qiangqiang Wang, Xiaoxiao Chen, Lifeng Chen, Lanjuan Li, Longxian Lv. Lactobacillus reuteri DSM 17938 alleviates d-galactosamine-induced liver failure in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Jan; 133(?):111000. doi:
10.1016/j.biopha.2020.111000
. [PMID: 33202285] - Yiwei Pu, Zhaocong Yang, Xuming Mo. Protective Effect of Luteolin on D-Galactosamine (D-Gal)/Lipopolysaccharide (LPS) Induced Hepatic Injury by in Mice.
BioMed research international.
2021; 2021(?):2252705. doi:
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Nov; 131(?):110736. doi:
10.1016/j.biopha.2020.110736
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Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2020 Nov; 69(11):1133-1142. doi:
10.1007/s00011-020-01393-3
. [PMID: 32809047] - Daniel Gaudet, Ewa Karwatowska-Prokopczuk, Seth J Baum, Eunju Hurh, Joyce Kingsbury, Victoria J Bartlett, Amparo L Figueroa, Philip Piscitelli, Walter Singleton, Joseph L Witztum, Richard S Geary, Sotirios Tsimikas, Louis St L O'Dea. Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia.
European heart journal.
2020 10; 41(40):3936-3945. doi:
10.1093/eurheartj/ehaa689
. [PMID: 32860031] - Yasuyuki Fujimoto, Mitsuru Kuwamura, Yasu-Taka Azuma. Deficiency of interleukin-19 exacerbates lipopolysaccharide/D-galactosamine-induced acute liver failure.
The Journal of veterinary medical science.
2020 Oct; 82(10):1450-1455. doi:
10.1292/jvms.20-0344
. [PMID: 32779617] - So Ra Kim, Eun Jung Park, Theodomir Dusabimana, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Kye Man Cho, Hwajin Kim, Sang Won Park. Platycodon grandiflorus Fermented Extracts Attenuate Endotoxin-Induced Acute Liver Injury in Mice.
Nutrients.
2020 Sep; 12(9):. doi:
10.3390/nu12092802
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Sep; 129(?):110375. doi:
10.1016/j.biopha.2020.110375
. [PMID: 32540645] - Erli Zhang, Jingbo Huang, Kun Wang, Qinlei Yu, Chao Zhu, Hua Ren. Pterostilbene Protects Against Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure by Upregulating the Nrf2 Pathway and Inhibiting NF-κB, MAPK, and NLRP3 Inflammasome Activation.
Journal of medicinal food.
2020 Sep; 23(9):952-960. doi:
10.1089/jmf.2019.4647
. [PMID: 32701014] - Marykate Killilea, Daniel M Kerr, Beth M Mallard, Michelle Roche, Antony M Wheatley. Exacerbated LPS/GalN-Induced Liver Injury in the Stress-Sensitive Wistar Kyoto Rat Is Associated with Changes in the Endocannabinoid System.
Molecules (Basel, Switzerland).
2020 Aug; 25(17):. doi:
10.3390/molecules25173834
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Journal of medicinal food.
2020 Aug; 23(8):895-901. doi:
10.1089/jmf.2019.0229
. [PMID: 31976801] - Jinxia Li, Qiuyun Zhang, Lianyin Gao, Yuqiong Du, Yu Chen. Efficacy of decoction from Jieduan Niwan formula on rat model of acute-on-chronic liver failure induced by porcine serum.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2020 08; 40(4):602-612. doi:
10.19852/j.cnki.jtcm.2020.04.009
. [PMID: 32744027] - Yong Yook Lee, Sung-Won Kim, Soo-Hyun Youn, Sun Hee Hyun, Jong-Su Kyung, Gyo In, Chae-Kyu Park, Hye Ryeon Jung, Seung Ju Moon, Min Jeung Kang, Eugene C Yi, Chang-Kyun Han. Biological Effects of Korean Red Ginseng Polysaccharides in Aged Rat Using Global Proteomic Approach.
Molecules (Basel, Switzerland).
2020 Jul; 25(13):. doi:
10.3390/molecules25133019
. [PMID: 32630349] - Chunpan Zhang, Hua Jin, Yan Wang, Changying Li, Xinyan Zhao, Yanmeng Li, Wen Shi, Yue Tian, Hufeng Xu, Dan Tian, Kai Liu, Jidong Jia, Guangyong Sun, Dong Zhang. Critical role of OX40 in drug-induced acute liver injury.
British journal of pharmacology.
2020 07; 177(14):3183-3196. doi:
10.1111/bph.15041
. [PMID: 32133635] - Yusuke Sato, Yoshiyuki Kinami, Kazuki Hashiba, Hideyoshi Harashima. Different kinetics for the hepatic uptake of lipid nanoparticles between the apolipoprotein E/low density lipoprotein receptor and the N-acetyl-d-galactosamine/asialoglycoprotein receptor pathway.
Journal of controlled release : official journal of the Controlled Release Society.
2020 06; 322(?):217-226. doi:
10.1016/j.jconrel.2020.03.006
. [PMID: 32145269] - Hua Zha, Dai-Qiong Fang, Aimee van der Reis, Kevin Chang, Li-Ya Yang, Jiao-Jiao Xie, Ding Shi, Qiao-Mai Xu, Ya-Ting Li, Lan-Juan Li. Vital members in the gut microbiotas altered by two probiotic Bifidobacterium strains against liver damage in rats.
BMC microbiology.
2020 06; 20(1):144. doi:
10.1186/s12866-020-01827-2
. [PMID: 32503418] - Xianwen Peng, Yongqiang Yang, Li Tang, Jingyuan Wan, Jie Dai, Longjiang Li, Jiayi Huang, Yi Shen, Ling Lin, Xianqiong Gong, Li Zhang. Therapeutic benefits of apocynin in mice with lipopolysaccharide/D-galactosamine-induced acute liver injury via suppression of the late stage pro-apoptotic AMPK/JNK pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 May; 125(?):110020. doi:
10.1016/j.biopha.2020.110020
. [PMID: 32106375] - Yisheng Luo, Yongqiang Yang, Yi Shen, Longjiang Li, Jiayi Huang, Li Tang, Li Zhang. Luzindole attenuates LPS/d-galactosamine-induced acute hepatitis in mice.
Innate immunity.
2020 05; 26(4):319-327. doi:
10.1177/1753425919890912
. [PMID: 31779498] - Mirca Marini, Alessia Tani, Mirko Manetti, Eleonora Sgambati. Characterization and distribution of sialic acids in human testicular seminoma.
Acta histochemica.
2020 Apr; 122(3):151532. doi:
10.1016/j.acthis.2020.151532
. [PMID: 32143917] - Li Hao, Ming-Wei Liu, Song-Tao Gu, Xue Huang, Hong Deng, Xu Wang. Sedum sarmentosum Bunge extract ameliorates lipopolysaccharide- and D-galactosamine-induced acute liver injury by attenuating the hedgehog signaling pathway via regulation of miR-124 expression.
BMC complementary medicine and therapies.
2020 Mar; 20(1):88. doi:
10.1186/s12906-020-2873-1
. [PMID: 32178661] - Zheng Li, Haihua Feng, Lu Han, Lu Ding, Bingyu Shen, Ye Tian, Lilei Zhao, Meiyu Jin, Qi Wang, Haiyan Qin, Jiaqi Cheng, Guowen Liu. Chicoric acid ameliorate inflammation and oxidative stress in Lipopolysaccharide and d-galactosamine induced acute liver injury.
Journal of cellular and molecular medicine.
2020 03; 24(5):3022-3033. doi:
10.1111/jcmm.14935
. [PMID: 31989756] - Hui-Zheng Fu, Yuan-Yu Ma, Shuang-Cheng Ma, Zhi-Qiang Zhou, Yue-Hua Luo. Two new iridoid glycosides from Callicarpa nudiflora.
Journal of Asian natural products research.
2020 Mar; 22(3):264-270. doi:
10.1080/10286020.2018.1557636
. [PMID: 30590951] - Baolong Liu, Yizhu Lu, Xingyi Chen, Philma Glora Muthuraj, Xingzhi Li, Mahesh Pattabiraman, Janos Zempleni, Stephen D Kachman, Sathish Kumar Natarajan, Jiujiu Yu. Protective Role of Shiitake Mushroom-Derived Exosome-Like Nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Nutrients.
2020 Feb; 12(2):. doi:
10.3390/nu12020477
. [PMID: 32069862] - Kaicen Wang, Longxian Lv, Ren Yan, Qiangqiang Wang, Huiyong Jiang, Wenrui Wu, Yating Li, Jianzhong Ye, Jingjing Wu, Liya Yang, Xiaoyuan Bian, Xianwan Jiang, Yanmeng Lu, Jiaojiao Xie, Qing Wang, Jian Shen, Lanjuan Li. Bifidobacterium longum R0175 Protects Rats against d-Galactosamine-Induced Acute Liver Failure.
mSphere.
2020 Jan; 5(1):. doi:
10.1128/msphere.00791-19
. [PMID: 31996423] - Lei-Lei Zhu, Ji-Duo Shen, Bao-Ying Wang, Shuai-Fei Lu, Bai Ming, Er-Ping Xu, Yu-Cheng Li, Xiao-Yan Fang. Depressive-like behaviors are induced by chronic liver injury in male and female mice.
Neuroscience letters.
2020 01; 718(?):134750. doi:
10.1016/j.neulet.2020.134750
. [PMID: 31926175] - Samrat Rakshit, Satendra K Nirala, Monika Bhadauria. Gallic Acid Protects from Acute Multiorgan Injury Induced by Lipopolysaccharide and D-galactosamine.
Current pharmaceutical biotechnology.
2020; 21(14):1489-1504. doi:
10.2174/1389201021666200615165732
. [PMID: 32538720] - Hirotaka Miyamoto, Kayoko Tsuda, Tominori Honda, Ayako Tokunaga, Shintaro Fumoto, Koyo Nishida. Influence of Liver Intoxication by Carbon Tetrachloride or D-Galactosamine on Absorption of Fluorescein Isothiocyanate-Dextran-10 and Other Marker Compounds with Different Molecular Weights from the Rat Liver Surface.
Biological & pharmaceutical bulletin.
2020; 43(2):319-324. doi:
10.1248/bpb.b19-00686
. [PMID: 32009118] - Gary J Haderski, Bojidar M Kandar, Craig M Brackett, Ilia M Toshkov, Christopher P Johnson, Geraldine M Paszkiewicz, Venkatesh Natarajan, Anatoli S Gleiberman, Andrei V Gudkov, Lyudmila G Burdelya. TLR5 agonist entolimod reduces the adverse toxicity of TNF while preserving its antitumor effects.
PloS one.
2020; 15(2):e0227940. doi:
10.1371/journal.pone.0227940
. [PMID: 32027657] - Zhaojian Zhang, Liang Tian, Kai Jiang. Propofol attenuates inflammatory response and apoptosis to protect d-galactosamine/lipopolysaccharide induced acute liver injury via regulating TLR4/NF-κB/NLRP3 pathway.
International immunopharmacology.
2019 Dec; 77(?):105974. doi:
10.1016/j.intimp.2019.105974
. [PMID: 31735662] - Qiangqiang Wang, Longxian Lv, Huiyong Jiang, Kaicen Wang, Ren Yan, Yating Li, Jianzhong Ye, Jingjing Wu, Qing Wang, Xiaoyuan Bian, Liya Yang, Xianwan Jiang, Jiaojiao Xie, Yanmeng Lu, Jian Shen, Lanjuan Li. Lactobacillus helveticus R0052 alleviates liver injury by modulating gut microbiome and metabolome in D-galactosamine-treated rats.
Applied microbiology and biotechnology.
2019 Dec; 103(23-24):9673-9686. doi:
10.1007/s00253-019-10211-8
. [PMID: 31713675] - Laura Gauthier, Mathieu Varache, Anne-Claude Couffin, Colette Lebrun, Pascale Delangle, Christelle Gateau, Isabelle Texier. Quantification of Surface GalNAc Ligands Decorating Nanostructured Lipid Carriers by UPLC-ELSD.
International journal of molecular sciences.
2019 Nov; 20(22):. doi:
10.3390/ijms20225669
. [PMID: 31726778] - Yan Li, Yongmei Zeng, Quanfang Huang, Shujuan Wen, Yuanyuan Wei, Ya Chen, Xiaolin Zhang, Facheng Bai, Zhongpeng Lu, Jinbin Wei, Xing Lin. Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Nov; 119(?):109435. doi:
10.1016/j.biopha.2019.109435
. [PMID: 31520915] - Rihua Xu, Aruhan, Lei Xiu, Shouxin Sheng, Yanchen Liang, Haochi Zhang, Yang Liu, He Tong, Ruiping Du, Xiao Wang. Exopolysaccharides from Lactobacillus buchneri TCP016 Attenuate LPS- and d-GalN-Induced Liver Injury by Modulating the Gut Microbiota.
Journal of agricultural and food chemistry.
2019 Oct; 67(42):11627-11637. doi:
10.1021/acs.jafc.9b04323
. [PMID: 31553177] - Wen-Ze Xiao, Li Zhang. Adiponectin receptor agonist AdipoRon relieves endotoxin-induced acute hepatitis in mice.
Chinese medical journal.
2019 Oct; 132(20):2438-2445. doi:
10.1097/cm9.0000000000000488
. [PMID: 31651516] - Xiang Song, Pan Shang, Zhenwei Sun, Mingzi Lu, Guoxing You, Shaoduo Yan, Gan Chen, Hong Zhou. Therapeutic effect of yttrium oxide nanoparticles for the treatment of fulminant hepatic failure.
Nanomedicine (London, England).
2019 10; 14(19):2519-2533. doi:
10.2217/nnm-2019-0154
. [PMID: 31317822] - Yang Li, Chenxi Guang, Na Zhao, Xinchi Feng, Feng Qiu. LC-MS/MS Method for Simultaneous Determination of Linarin and Its Metabolites in Rat Plasma and Liver Tissue Samples: Application to Pharmacokinetic and Liver Tissue Distribution Study After Oral Administration of Linarin.
Molecules (Basel, Switzerland).
2019 Sep; 24(18):. doi:
10.3390/molecules24183342
. [PMID: 31540332] - Pallerla Praneetha, Vanapatla Swaroopa Rani, Vatsavaya Satyanarayana Raju, Yellu Narasimha Reddy, Bobbala Ravi Kumar. Hepatoprotective studies on methanolic extract of caryopses of Echinochloa colona Link.
Pakistan journal of pharmaceutical sciences.
2019 Sep; 32(5):1949-1956. doi:
NULL
. [PMID: 31813857] - Yongqiang Yang, Ruyue Shao, Rong Jiang, Min Zhu, Li Tang, Longjiang Li, Li Zhang. β-Hydroxybutyrate exacerbates lipopolysaccharide/ d-galactosamine-induced inflammatory response and hepatocyte apoptosis in mice.
Journal of biochemical and molecular toxicology.
2019 Sep; 33(9):e22372. doi:
10.1002/jbt.22372
. [PMID: 31332890] - Cong Zhang, Fangxin Hu, Han Zhang, Shihong Chen, Ruo Yuan. An electrochemiluminescence biosensor for the detection of soybean agglutinin based on carboxylated graphitic carbon nitride as luminophore.
Analytical and bioanalytical chemistry.
2019 Sep; 411(23):6049-6056. doi:
10.1007/s00216-019-01986-w
. [PMID: 31280477] - Shao-Yuan Wang, Mei Li, Lu-Yang Miao, Song Wu, Yuan-Feng Tong, Wen-Xuan Zhang, Yu-Yang Zhang, Hua Sun. Protective effects of a novel water-soluble biphenyl compound WLP-S-14 against acute-on-chronic liver failure in rats.
Journal of Asian natural products research.
2019 Sep; 21(9):928-938. doi:
10.1080/10286020.2019.1585822
. [PMID: 31111726] - Xiao Wang, Chao Han, Jiaojiao Qin, Yuanyuan Wei, Xufeng Qian, Yongzhan Bao, Wanyu Shi. Pretreatment with Salvia miltiorrhiza Polysaccharides Protects from Lipopolysaccharides/d-Galactosamine-Induced Liver Injury in Mice Through Inhibiting TLR4/MyD88 Signaling Pathway.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
2019 08; 39(8):495-505. doi:
10.1089/jir.2018.0137
. [PMID: 31074668] - Cuiyun Zou, Minglei Xu, Leling Chen, Qingying Liu, Yuanyuan Zhou, Zhenzhu Sun, Huaqun Ye, Ningning Su, Chaoxia Ye, Anli Wang. Xiaochaihu Decoction reduces hepatic steatosis and improves D-GalN/LPS-induced liver injury in hybrid grouper (Epinephelus lanceolatus♂ × Epinephelus fuscoguttatus♀).
Fish & shellfish immunology.
2019 Aug; 91(?):293-305. doi:
10.1016/j.fsi.2019.05.025
. [PMID: 31100441] - Man You, Rui-Fang Li, Zi-Han Gao, Yuan-Ye Li, Wei-Yi Liu, Jian-Gang Wang, Hong-Wei Wang, San-Qiang Li. [Effects of saikosaponin b_2 on inflammation and energy metabolism in mice with acute liver injury induced by LPS/GalN].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2019 Jul; 44(14):2966-2971. doi:
10.19540/j.cnki.cjcmm.20190521.415
. [PMID: 31602841] - Yinhong Zhu, Xiaobei Chen, Xianlin Rao, Chunhua Zheng, Xiaomou Peng. Saikosaponin a ameliorates lipopolysaccharide and d‑galactosamine-induced liver injury via activating LXRα.
International immunopharmacology.
2019 Jul; 72(?):131-137. doi:
10.1016/j.intimp.2019.03.049
. [PMID: 30981078] - Qing Tian, Guijie Wang, Yamin Zhang, Fubo Zhang, Long Yang, Zirong Liu, Zhongyang Shen. Engeletin inhibits Lipopolysaccharide/d-galactosamine-induced liver injury in mice through activating PPAR-γ.
Journal of pharmacological sciences.
2019 Jul; 140(3):218-222. doi:
10.1016/j.jphs.2019.06.011
. [PMID: 31473044] - Changming Yang, Lingling He, Chan Wang, Yang Huang, Aitao Wang, Xin Li, Jine Ao. Dexmedetomidine alleviated lipopolysaccharide/D-galactosamine-induced acute liver injury in mice.
International immunopharmacology.
2019 Jul; 72(?):367-373. doi:
10.1016/j.intimp.2019.04.019
. [PMID: 31030092] - Yan-Min Liu, Liu-Luan Zhu, Rui Li, Jin-Liang Zhang, Shan-Shan Yao, Xiao-Bing Zhou, Hui Zeng, Xian-Bo Wang. Xijiao Dihuang Decoction () and Rehmannia glutinosa Libosch. protect mice against lipopolysaccharide and tumor necrosis factor alpha-induced acute liver failure.
Chinese journal of integrative medicine.
2019 Jun; 25(6):446-453. doi:
10.1007/s11655-015-2141-2
. [PMID: 26016454] - Ya-Chao Tao, Meng-Lan Wang, Dong-Bo Wu, Chen Luo, Hong Tang, En-Qiang Chen. Apolipoprotein A5 alleviates LPS/D-GalN-induced fulminant liver failure in mice by inhibiting TLR4-mediated NF-κB pathway.
Journal of translational medicine.
2019 05; 17(1):151. doi:
10.1186/s12967-019-1900-9
. [PMID: 31077206] - Xuejun Kong, Shaojun Hao, Chongxian Li, Huamin Wang, Yanling Gao, Feng Su, Ling Wang, Youshu Sun, Zhengchen Zhang. Protective Effect of Compound Cotinus coggygria Oral Liquid on Mice Acute Liver Injury Induced by D-Galactosamine.
Annals of clinical and laboratory science.
2019 May; 49(3):361-367. doi:
NULL
. [PMID: 31308036] - Ran Zhou, Shih-Heng Chen, Guorong Li, Hui-Ling Chen, YuXin Liu, Hung-Ming Wu, Yubao Wang, Jing Feng, Jau-Shyong Hong. Ultralow doses of dextromethorphan protect mice from endotoxin-induced sepsis-like hepatotoxicity.
Chemico-biological interactions.
2019 Apr; 303(?):50-56. doi:
10.1016/j.cbi.2019.02.025
. [PMID: 30822415] - Yu-Jen Huang, Chih-Yuan Lee, Jerry Cao, Hsuan-Shu Lee, Chih-Hao Chang, Po-Da Chen, Yao-Ming Wu. Therapeutic Potential of Plasma Proteins Derived from Umbilical Cord Blood for Acute Liver Failure.
Molecular pharmaceutics.
2019 03; 16(3):1092-1104. doi:
10.1021/acs.molpharmaceut.8b01108
. [PMID: 30698974] - Yi Li, Nian Wang, Yongfang Jiang. Geraniol protects against lipopolysaccharide and D-galactosamine-induced fulminant hepatic failure by activating PPARγ.
Microbial pathogenesis.
2019 Mar; 128(?):7-12. doi:
10.1016/j.micpath.2018.11.054
. [PMID: 30550845] - Danmei Tian, Fangfang Wang, Menglong Duan, Lingyun Cao, Youwei Zhang, Xinsheng Yao, Jinshan Tang. Coumarin Analogues from the Citrus grandis (L.) Osbeck and Their Hepatoprotective Activity.
Journal of agricultural and food chemistry.
2019 Feb; 67(7):1937-1947. doi:
10.1021/acs.jafc.8b06489
. [PMID: 30689373] - Zheng Li, Haihua Feng, Yue Wang, Bingyu Shen, Ye Tian, Lin Wu, Qiaoling Zhang, Meiyu Jin, Guowen Liu. Rosmarinic acid protects mice from lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting MAPKs/NF-κB and activating Nrf2/HO-1 signaling pathways.
International immunopharmacology.
2019 Feb; 67(?):465-472. doi:
10.1016/j.intimp.2018.12.052
. [PMID: 30597292] - Amarendar Reddy Maddirala, Roger Klein, Jerome S Pinkner, Vasilios Kalas, Scott J Hultgren, James W Janetka. Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through Iterative Rational Drug Design.
Journal of medicinal chemistry.
2019 01; 62(2):467-479. doi:
10.1021/acs.jmedchem.8b01561
. [PMID: 30540910] - Shigeaki Nakazawa, Ryoichi Imamura, Masataka Kawamura, Taigo Kato, Toyofumi Abe, Tomoko Namba, Hirotsugu Iwatani, Kazuaki Yamanaka, Motohide Uemura, Hidefumi Kishikawa, Kenji Nishimura, Kazumasa Oka, Michiko Tajiri, Yoshinao Wada, Norio Nonomura. Difference in IgA1 O-glycosylation between IgA deposition donors and IgA nephropathy recipients.
Biochemical and biophysical research communications.
2019 01; 508(4):1106-1112. doi:
10.1016/j.bbrc.2018.12.014
. [PMID: 30553446] - Cyrielle Billon, Meghan H Murray, Amer Avdagic, Thomas P Burris. RORγ regulates the NLRP3 inflammasome.
The Journal of biological chemistry.
2019 01; 294(1):10-19. doi:
10.1074/jbc.ac118.002127
. [PMID: 30455347]