Chebulinic acid (BioDeep_00000003756)

 

Secondary id: BioDeep_00000230707

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


2-[(4R,5S,7R,8R,11S,12S,13S,21S)-13,17,18-trihydroxy-2,10,14-trioxo-5,21-bis[(3,4,5-trihydroxybenzoyl)oxy]-7-[(3,4,5-trihydroxybenzoyl)oxymethyl]-3,6,9,15-tetraoxatetracyclo[10.7.1.14,8.016,20]henicosa-1(19),16(20),17-trien-11-yl]acetic acid

化学式: C41H32O27 (956.1131)
中文名称: 诃子林鞣酸
谱图信息: 最多检出来源 Astragalus membranaceus(otcml) 55.56%

Reviewed

Last reviewed on 2024-09-27.

Cite this Page

Chebulinic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/chebulinic_acid (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000003756). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=C(C=C(C(=C1O)O)O)C(=O)OCC2C3C(C(C(O2)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C6=C5C(C(C(=O)O3)CC(=O)O)C(C(=O)O6)O)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O
InChI: InChI=1S/C41H32O27/c42-15-1-10(2-16(43)26(15)51)35(56)62-9-22-31-33(66-36(57)11-3-17(44)27(52)18(45)4-11)34(41(63-22)68-37(58)12-5-19(46)28(53)20(47)6-12)67-38(59)13-7-21(48)29(54)32-25(13)24(30(55)40(61)65-32)14(8-23(49)50)39(60)64-31/h1-7,14,22,24,30-31,33-34,41-48,51-55H,8-9H2,(H,49,50)

描述信息

Chebulinic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=18942-26-2 (retrieved 2024-09-27) (CAS RN: 18942-26-2). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

4 个代谢物同义名

2-[(4R,5S,7R,8R,11S,12S,13S,21S)-13,17,18-trihydroxy-2,10,14-trioxo-5,21-bis[(3,4,5-trihydroxybenzoyl)oxy]-7-[(3,4,5-trihydroxybenzoyl)oxymethyl]-3,6,9,15-tetraoxatetracyclo[10.7.1.14,8.016,20]henicosa-1(19),16(20),17-trien-11-yl]acetic acid; Chebulinic acid; CID 250396; Chebulinic acid



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

29 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ADIG, AIMP2, ANG, ANXA5, BCL2, CASP3, CASP7, CAT, NQO1, SOD1, VEGFA
Peripheral membrane protein 4 ACHE, ANXA5, CYP1B1, ERVW-1
Endoplasmic reticulum membrane 3 BCL2, CYP1A2, CYP1B1
Nucleus 11 ACHE, ADIG, AIMP2, ANG, BCL2, CASP3, CASP7, GABPA, NQO1, SOD1, VEGFA
autophagosome 1 MAP1LC3A
cytosol 10 AIMP2, ANG, ANXA5, BCL2, CASP3, CASP7, CAT, MAP1LC3A, NQO1, SOD1
dendrite 1 NQO1
nucleoplasm 4 CASP3, CASP7, GABPA, SOD1
Cell membrane 2 ACHE, PECAM1
Lipid-anchor 1 MAP1LC3A
Synapse 2 ACHE, NQO1
cell junction 1 PECAM1
cell surface 2 ACHE, VEGFA
glutamatergic synapse 2 CASP3, MAP1LC3A
Golgi apparatus 2 ACHE, VEGFA
growth cone 1 ANG
neuromuscular junction 1 ACHE
neuronal cell body 4 ANG, CASP3, NQO1, SOD1
sarcolemma 1 ANXA5
Cytoplasm, cytosol 3 AIMP2, CASP7, NQO1
plasma membrane 3 ACHE, ERVW-1, PECAM1
Membrane 9 ACHE, ADIG, AIMP2, ANXA5, BCL2, CAT, CYP1B1, NQO1, VEGFA
extracellular exosome 5 ANXA5, CAT, MMP9, PECAM1, SOD1
endoplasmic reticulum 2 BCL2, VEGFA
extracellular space 8 ACHE, ANG, CASP7, CXCL8, MMP9, PECAM1, SOD1, VEGFA
perinuclear region of cytoplasm 1 ACHE
adherens junction 1 VEGFA
mitochondrion 4 BCL2, CAT, CYP1B1, SOD1
protein-containing complex 4 BCL2, CAT, PECAM1, SOD1
intracellular membrane-bounded organelle 4 CAT, CYP1A2, CYP1B1, MAP1LC3A
Microsome membrane 2 CYP1A2, CYP1B1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 ERVW-1, PECAM1
Secreted 5 ACHE, ADIG, ANG, CXCL8, VEGFA
extracellular region 9 ACHE, ADIG, ANG, ANXA5, CAT, CXCL8, MMP9, SOD1, VEGFA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 2 ADIG, BCL2
mitochondrial outer membrane 1 BCL2
mitochondrial matrix 2 CAT, SOD1
Extracellular side 1 ACHE
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 ANXA5, PECAM1
Secreted, extracellular space, extracellular matrix 2 MMP9, VEGFA
actin cytoskeleton 1 ANG
cytoplasmic vesicle 1 SOD1
nucleolus 1 ANG
axon cytoplasm 1 SOD1
cell-cell junction 1 PECAM1
Membrane raft 1 PECAM1
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 MAP1LC3A
focal adhesion 2 ANXA5, CAT
microtubule 1 MAP1LC3A
extracellular matrix 1 VEGFA
Peroxisome 2 CAT, SOD1
basement membrane 2 ACHE, ANG
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
mitochondrial intermembrane space 1 SOD1
collagen-containing extracellular matrix 2 ANXA5, MMP9
secretory granule 1 VEGFA
dendrite cytoplasm 1 SOD1
Late endosome 1 MAP1LC3A
Zymogen granule membrane 1 ANXA5
chromatin 1 GABPA
Cytoplasmic vesicle, autophagosome membrane 1 MAP1LC3A
autophagosome membrane 1 MAP1LC3A
Chromosome 1 ANG
Secreted, extracellular space 1 CASP7
Nucleus, nucleolus 1 ANG
Lipid-anchor, GPI-anchor 1 ACHE
organelle membrane 1 MAP1LC3A
Endomembrane system 1 MAP1LC3A
Lipid droplet 1 ADIG
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 1 ANG
side of membrane 1 ACHE
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 2 CAT, MMP9
secretory granule lumen 1 CAT
secretory granule membrane 1 PECAM1
platelet alpha granule lumen 1 VEGFA
tertiary granule lumen 1 MMP9
endocytic vesicle 1 ANG
vesicle membrane 1 ANXA5
synaptic cleft 1 ACHE
death-inducing signaling complex 1 CASP3
[Transmembrane protein]: Cell membrane 1 ERVW-1
[Surface protein]: Cell membrane 1 ERVW-1
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
[Isoform Long]: Cell membrane 1 PECAM1
platelet alpha granule membrane 1 PECAM1
Autolysosome 1 MAP1LC3A
angiogenin-PRI complex 1 ANG
catalase complex 1 CAT
endothelial microparticle 1 ANXA5
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Isoform Delta15]: Cell junction 1 PECAM1
[Isoform H]: Cell membrane 1 ACHE
[Syncytin-1]: Virion 1 ERVW-1


文献列表

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  • Naiju Thomas, Poonam Patil, Anjana Sharma, Sandeep Kumar, Vikas Kumar Singh, Kalichamy Alagarasu, Deepti Parashar, Suman Tapryal. Studies on the antiviral activity of chebulinic acid against dengue and chikungunya viruses and in silico investigation of its mechanism of inhibition. Scientific reports. 2022 06; 12(1):10397. doi: 10.1038/s41598-022-13923-6. [PMID: 35729191]
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