Aspartyl phosphate (BioDeep_00001869289)

Main id: BioDeep_00000005091

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Aspartyl phosphate

化学式: C4H8NO7P (213.0038)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(C(=O)O)N)C(=O)OP(=O)(O)O
InChI: InChI=1S/C4H8NO7P/c5-2(4(7)8)1-3(6)12-13(9,10)11/h2H,1,5H2,(H,7,8)(H2,9,10,11)/t2-/m0/s1

描述信息

D018377 - Neurotransmitter Agents > D018846 - Excitatory Amino Acids

同义名列表

2 个代谢物同义名

Aspartyl phosphate; 4-Phospho-L-aspartate



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(6)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 BRCA1, CDK16, MAPK8IP1, PMM1, PMM2, PSPH, SLC9A1
Peripheral membrane protein 1 CDK16
Endoplasmic reticulum membrane 5 ATP13A1, HSP90B1, MAPK8IP1, PLN, SLN
Mitochondrion membrane 1 PLN
Nucleus 6 BRCA1, CDK16, DLST, HSP90B1, MAPK8IP1, PTMS
cytosol 8 ATP12A, CDK16, DLST, HSP90B1, MAPK8IP1, PMM1, PMM2, PSPH
dendrite 2 MAPK8IP1, PDYN
mitochondrial membrane 2 MAPK8IP1, PLN
nuclear body 1 BRCA1
nucleoplasm 5 ATP2B1, BRCA1, DLST, PMM2, SLC9A1
Cell membrane 3 ATP2B1, CDK16, SLC9A1
Cytoplasmic side 1 CDK16
lamellipodium 1 SLC9A1
Multi-pass membrane protein 4 ATP12A, ATP13A1, ATP2B1, SLC9A1
Synapse 3 ATP2B1, MAPK8IP1, PDYN
cell surface 1 SLC9A1
glutamatergic synapse 1 ATP2B1
neuronal cell body 4 MAPK8IP1, PDYN, PMM1, PMM2
presynaptic membrane 1 ATP2B1
smooth endoplasmic reticulum 1 HSP90B1
synaptic vesicle 1 CDK16
Cytoplasm, cytosol 1 PSPH
Cytoplasmic vesicle, secretory vesicle 1 CDK16
plasma membrane 7 ATP12A, ATP2B1, BRCA1, CDK16, MAPK8IP1, PDYN, SLC9A1
synaptic vesicle membrane 1 ATP2B1
Membrane 8 ATP13A1, ATP2B1, BRCA1, DLST, HSP90B1, PLN, SLC9A1, SLN
apical plasma membrane 2 ATP12A, SLC9A1
basolateral plasma membrane 3 ATP12A, ATP2B1, SLC9A1
extracellular exosome 3 ATP2B1, HSP90B1, SLC9A1
endoplasmic reticulum 2 HSP90B1, PLN
perinuclear region of cytoplasm 4 HSP90B1, MAPK8IP1, PLN, SLC9A1
intercalated disc 1 SLC9A1
mitochondrion 3 DLST, PLN, SLC9A1
protein-containing complex 2 BRCA1, HSP90B1
intracellular membrane-bounded organelle 1 ATP2B1
Secreted 1 PDYN
extracellular region 2 HSP90B1, PDYN
cytoplasmic side of plasma membrane 1 CDK16
Single-pass membrane protein 2 PLN, SLN
hippocampal mossy fiber to CA3 synapse 1 PDYN
Mitochondrion matrix 1 DLST
mitochondrial matrix 1 DLST
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
actin cytoskeleton 1 ATP12A
T-tubule 1 SLC9A1
microtubule cytoskeleton 1 CDK16
midbody 1 HSP90B1
Apical cell membrane 1 ATP12A
Cytoplasm, perinuclear region 1 MAPK8IP1
Membrane raft 1 SLC9A1
focal adhesion 2 HSP90B1, SLC9A1
sarcoplasmic reticulum 2 PLN, SLN
collagen-containing extracellular matrix 1 HSP90B1
lateral plasma membrane 1 ATP2B1
neuron projection 1 CDK16
cell projection 1 ATP2B1
Chromosome 1 BRCA1
[Isoform 5]: Cytoplasm 1 BRCA1
Basolateral cell membrane 2 ATP2B1, SLC9A1
lateral element 1 BRCA1
Melanosome 1 HSP90B1
Presynaptic cell membrane 1 ATP2B1
sperm plasma membrane 1 HSP90B1
ubiquitin ligase complex 1 BRCA1
endoplasmic reticulum lumen 1 HSP90B1
male germ cell nucleus 1 BRCA1
axon terminus 1 PDYN
XY body 1 BRCA1
Sarcoplasmic reticulum membrane 2 PLN, SLN
immunological synapse 1 ATP2B1
neuronal dense core vesicle 1 PDYN
oxoglutarate dehydrogenase complex 1 DLST
Sarcoplasmic reticulum lumen 1 HSP90B1
ribonucleoprotein complex 1 BRCA1
Synapse, synaptosome 1 CDK16
intracellular non-membrane-bounded organelle 1 BRCA1
DNA repair complex 1 BRCA1
BRCA1-C complex 1 BRCA1
cyclin-dependent protein kinase holoenzyme complex 1 CDK16
oxidoreductase complex 1 DLST
endocytic vesicle lumen 1 HSP90B1
endoplasmic reticulum chaperone complex 1 HSP90B1
oxoadipate dehydrogenase complex 1 DLST
photoreceptor ribbon synapse 1 ATP2B1
calcium ion-transporting ATPase complex 1 PLN
cation-transporting ATPase complex 1 SLC9A1
potassium:proton exchanging ATPase complex 1 ATP12A
BRCA1-A complex 1 BRCA1
BRCA1-B complex 1 BRCA1
BRCA1-BARD1 complex 1 BRCA1
gamma-tubulin ring complex 1 BRCA1
nuclear ubiquitin ligase complex 1 BRCA1
dentate gyrus mossy fiber 1 MAPK8IP1


文献列表

  • Gérald Larrouy-Maumus, Geoff Kelly, Luiz Pedro Sório de Carvalho. Chemical mechanism of glycerol 3-phosphate phosphatase: pH-dependent changes in the rate-limiting step. Biochemistry. 2014 Jan; 53(1):143-51. doi: 10.1021/bi400856y. [PMID: 24359335]
  • Patrice Catty, Sylvain Boutigny, Roger Miras, Jacques Joyard, Norbert Rolland, Daphné Seigneurin-Berny. Biochemical characterization of AtHMA6/PAA1, a chloroplast envelope Cu(I)-ATPase. The Journal of biological chemistry. 2011 Oct; 286(42):36188-97. doi: 10.1074/jbc.m111.241034. [PMID: 21878617]
  • Anna Zorina, Natalia Stepanchenko, Galina V Novikova, Maria Sinetova, Vladimir B Panichkin, Igor E Moshkov, Vladislav V Zinchenko, Sergey V Shestakov, Iwane Suzuki, Norio Murata, Dmitry A Los. Eukaryotic-like Ser/Thr protein kinases SpkC/F/K are involved in phosphorylation of GroES in the Cyanobacterium synechocystis. DNA research : an international journal for rapid publication of reports on genes and genomes. 2011 Jun; 18(3):137-51. doi: 10.1093/dnares/dsr006. [PMID: 21551175]
  • Stephane Paris, Peter M Wessel, Renaud Dumas. Overproduction, purification, and characterization of recombinant bifunctional threonine-sensitive aspartate kinase-homoserine dehydrogenase from Arabidopsis thaliana. Protein expression and purification. 2002 Feb; 24(1):105-10. doi: 10.1006/prep.2001.1539. [PMID: 11812230]
  • Stephane Paris, Peter M Wessel, Renaud Dumas. Overproduction, purification, and characterization of recombinant aspartate semialdehyde dehydrogenase from Arabidopsis thaliana. Protein expression and purification. 2002 Feb; 24(1):99-104. doi: 10.1006/prep.2001.1538. [PMID: 11812229]
  • J R Tuckerman, G Gonzalez, M A Gilles-Gonzalez. Complexation precedes phosphorylation for two-component regulatory system FixL/FixJ of Sinorhizobium meliloti. Journal of molecular biology. 2001 May; 308(3):449-55. doi: 10.1006/jmbi.2001.4591. [PMID: 11327779]
  • E E Strehler, D A Zacharias. Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps. Physiological reviews. 2001 Jan; 81(1):21-50. doi: 10.1152/physrev.2001.81.1.21. [PMID: 11152753]
  • D Yan, H S Cho, C A Hastings, M M Igo, S Y Lee, J G Pelton, V Stewart, D E Wemmer, S Kustu. Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators. Proceedings of the National Academy of Sciences of the United States of America. 1999 Dec; 96(26):14789-94. doi: 10.1073/pnas.96.26.14789. [PMID: 10611291]
  • S A Anderson, S Jiang, A J Mukkada. The beta-aspartyl phosphate intermediate in a Leishmania donovani promastigote plasma membrane P-type ATPase. Biochimica et biophysica acta. 1994 Oct; 1195(1):81-8. doi: 10.1016/0005-2736(94)90012-4. [PMID: 7918569]
  • P L Jørgensen. Conformational changes in the alpha-subunit and cation transport by pure Na, K-ATPase. The Tokai journal of experimental and clinical medicine. 1982; 7 Suppl(?):51-60. doi: . [PMID: 6310826]
  • J B Dame, G A Scarborough. Identification of the phosphorylated intermediate of the Neurospora plasma membrane H+-ATPase as beta-aspartyl phosphate. The Journal of biological chemistry. 1981 Oct; 256(20):10724-30. doi: . [PMID: 6457042]