4-Hydroxy-2,4,6-trichlorobiphenyl (BioDeep_00001869272)

Main id: BioDeep_00000009748

 

Industrial Pollutants


代谢物信息卡片


4-Hydroxy-2,4,6-trichlorobiphenyl

化学式: C12H7Cl3O (271.9562)
中文名称: 4-羟基-2,4,6-三氯联苯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C2=C(C=C(C=C2Cl)Cl)Cl)O
InChI: InChI=1S/C12H7Cl3O/c13-8-5-10(14)12(11(15)6-8)7-1-3-9(16)4-2-7/h1-6,16H

描述信息

D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls

同义名列表

2 个代谢物同义名

4-Hydroxy-2,4,6-trichlorobiphenyl; 2,4,6-Trichloro-4'-biphenylol



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 AHR, CYP2B6, ESR1, GPER1, NR1I3, PGR, TGFB1
Peripheral membrane protein 2 CYP2B6, ESR1
Endoplasmic reticulum membrane 2 CYP2B6, GPER1
Mitochondrion membrane 1 GPER1
Nucleus 8 AHR, ALDH7A1, ESR1, ESR2, GPER1, NR1I3, PGR, TGFB1
cytosol 6 AHR, ALDH7A1, ESR1, GPER1, NR1I3, PGR
dendrite 1 GPER1
mitochondrial membrane 1 GPER1
trans-Golgi network 1 GPER1
nucleoplasm 6 AHR, ESR1, ESR2, GPER1, NR1I3, PGR
Cell membrane 2 EFNA5, ESR1
Cytoplasmic side 1 ESR1
Cell projection, axon 1 GPER1
Multi-pass membrane protein 2 GPER1, KCNA3
Golgi apparatus membrane 1 GPER1
cell surface 2 C3, TGFB1
dendritic shaft 1 GPER1
glutamatergic synapse 1 KCNA3
Golgi apparatus 2 ESR1, GPER1
Golgi membrane 1 GPER1
neuronal cell body 1 TGFB1
presynaptic membrane 2 GPER1, KCNA3
plasma membrane 7 C3, EFNA5, ESR1, GPER1, KCNA3, PGR, TGFB1
presynaptic active zone 1 GPER1
Membrane 3 ESR1, GPER1, KCNA3
axon 3 GPER1, KCNA3, TGFB1
caveola 1 EFNA5
extracellular exosome 3 ALDH7A1, BMP3, C3
endoplasmic reticulum 1 GPER1
extracellular space 3 BMP3, C3, TGFB1
perinuclear region of cytoplasm 2 GPER1, KCNA3
adherens junction 1 EFNA5
mitochondrion 2 ALDH7A1, ESR2
protein-containing complex 3 AHR, C3, ESR1
intracellular membrane-bounded organelle 3 CYP2B6, ESR2, GPER1
Microsome membrane 1 CYP2B6
postsynaptic density 1 GPER1
Secreted 3 BMP3, C3, TGFB1
extracellular region 3 BMP3, C3, TGFB1
mitochondrial outer membrane 1 PGR
hippocampal mossy fiber to CA3 synapse 1 GPER1
mitochondrial matrix 1 ALDH7A1
transcription regulator complex 2 AHR, ESR1
external side of plasma membrane 1 EFNA5
Secreted, extracellular space, extracellular matrix 1 TGFB1
nucleolus 1 GPER1
Early endosome 1 GPER1
recycling endosome 1 GPER1
postsynaptic membrane 1 KCNA3
Membrane raft 1 KCNA3
Cytoplasm, cytoskeleton 1 NR1I3
GABA-ergic synapse 1 EFNA5
extracellular matrix 1 TGFB1
basement membrane 1 EFNA5
collagen-containing extracellular matrix 1 TGFB1
secretory granule 1 TGFB1
chromatin 5 AHR, ESR1, ESR2, NR1I3, PGR
cytoskeleton 1 NR1I3
[Isoform 1]: Mitochondrion 1 ALDH7A1
blood microparticle 2 C3, TGFB1
Lipid-anchor, GPI-anchor 1 EFNA5
[Isoform 2]: Cell membrane 1 KCNA3
nuclear envelope 1 GPER1
Membrane, caveola 1 EFNA5
aryl hydrocarbon receptor complex 1 AHR
Cytoplasmic vesicle membrane 1 GPER1
Cell projection, dendrite 1 GPER1
[Isoform 2]: Cytoplasm, cytosol 1 ALDH7A1
euchromatin 1 ESR1
side of membrane 1 EFNA5
voltage-gated potassium channel complex 1 KCNA3
secretory granule lumen 1 C3
Golgi lumen 1 TGFB1
endoplasmic reticulum lumen 1 C3
platelet alpha granule lumen 1 TGFB1
axon terminus 1 GPER1
azurophil granule lumen 1 C3
calyx of Held 1 KCNA3
[Isoform 1]: Nucleus 1 ESR1
[Isoform 1]: Cell membrane 1 KCNA3
keratin filament 1 GPER1
dendritic spine head 1 GPER1
Cell projection, dendritic spine membrane 1 GPER1
dendritic spine membrane 1 GPER1
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix 1 TGFB1
[Transforming growth factor beta-1]: Secreted 1 TGFB1
[Isoform 4]: Mitochondrion outer membrane 1 PGR
[Isoform 3]: Cytoplasm, perinuclear region 1 KCNA3
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR


文献列表

  • D B Carlson, D E Williams. 4-hydroxy-2',4',6'-trichlorobiphenyl and 4-hydroxy-2',3',4',5'-tetrachlorobiphenyl are estrogenic in rainbow trout. Environmental toxicology and chemistry. 2001 Feb; 20(2):351-8. doi: . [PMID: 11351435]
  • S H Safe, L Pallaroni, K Yoon, K Gaido, S Ross, B Saville, D McDonnellc. Toxicology of environmental estrogens. Reproduction, fertility, and development. 2001; 13(4):307-15. doi: 10.1071/rd00108. [PMID: 11800169]
  • K C Reinhart, R K Dubey, P J Keller, U Lauper, M Rosselli. Xeno-oestrogens and phyto-oestrogens induce the synthesis of leukaemia inhibitory factor by human and bovine oviduct cells. Molecular human reproduction. 1999 Oct; 5(10):899-907. doi: 10.1093/molehr/5.10.899. [PMID: 10508216]
  • L G Pedersen, T A Darden, S J Oatley, J D McKinney. A theoretical study of the binding of polychlorinated biphenyls (PCBs), dibenzodioxins, and dibenzofuran to human plasma prealbumin. Journal of medicinal chemistry. 1986 Dec; 29(12):2451-7. doi: 10.1021/jm00162a006. [PMID: 3097319]