Tamsulosin (BioDeep_00001867818)
Main id: BioDeep_00000002542
natural product
代谢物信息卡片
Tamsulosin
化学式: C20H28N2O5S (408.1719)
中文名称: 坦索罗辛
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOC1=CC=CC=C1OCCNC(C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N
InChI: InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1
描述信息
G - Genito urinary system and sex hormones > G04 - Urologicals > G04C - Drugs used in benign prostatic hypertrophy > G04CA - Alpha-adrenoreceptor antagonists
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists
D000089162 - Genitourinary Agents > D064804 - Urological Agents
Tamsulosin ((R)-(-)-YM12617 free base) is an inhibitor of α1-adrenergic receptor. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth in animal models[1].
同义名列表
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:9398
- KEGG: C07124
- KEGGdrug: D08560
- PubChem: 129211
- DrugBank: DB00706
- ChEMBL: CHEMBL836
- MeSH: Tamsulosin
- CAS: 106133-20-4
- PubChem: 9334
- PDB-CCD: JGX
- NIKKAJI: J340.699G
- RefMet: Tamsulosin
- medchemexpress: HY-B0661
- KNApSAcK: 9398
- LOTUS: LTS0142195
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 3398 - Magnoliopsida: LTS0142195
- 13215 - Piper: LTS0142195
- 13216 - Piper nigrum: LTS0142195
- 16739 - Piperaceae: LTS0142195
- 58023 - Tracheophyta: LTS0142195
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hong-Ping Shen, Jing-Xian Xu, Li Wang, Zhi-Bo Zheng, Yi Yu, Ke-Qi Zhu, Xue-Qin Chen. [Simiaotongzhuo Decoction for the treatment of type III prostatitis: A clinical observation].
Zhonghua nan ke xue = National journal of andrology.
2023 Apr; 29(4):348-352. doi:
". [PMID: 38598220] - Nawal M Alrasheed, Raghad B Alammari, Tahani K Alshammari, Maha A Alamin, Abeer O Alharbi, Asma S Alonazi, Anfal F Bin Dayel, Nouf M Alrasheed. α1A Adrenoreceptor blockade attenuates myocardial infarction by modulating the integrin-linked kinase/TGF-β/Smad signaling pathways.
BMC cardiovascular disorders.
2023 Mar; 23(1):153. doi:
10.1186/s12872-023-03188-w. [PMID: 36964489] - Rui-Kun Zhang, Kun Yan, Hai-Feng Chen, Yang Zhang, Gui-Jin Li, Xiao-Gang Chen, Lin-Pu Ge, Feng Cheng, Zhi-Neng Chen, Xin-Miao Yao. Anti-osteoporotic drugs affect the pathogenesis of gut microbiota and its metabolites: a clinical study.
Frontiers in cellular and infection microbiology.
2023; 13(?):1091083. doi:
10.3389/fcimb.2023.1091083. [PMID: 37475958] - Rana B Bakhaidar, Khaled M Hosny, Imman M Mahier, Waleed Y Rizq, Awaji Y Safhi, Deena M Bukhary, Muhammad H Sultan, Haitham A Bukhary, Osama A Madkhali, Fahad Y Sabei. Development and optimization of a tamsulosin nanostructured lipid carrier loaded with saw palmetto oil and pumpkin seed oil for treatment of benign prostatic hyperplasia.
Drug delivery.
2022 Dec; 29(1):2579-2591. doi:
10.1080/10717544.2022.2105448. [PMID: 35915055] - Abdelwahab Hashem, Ahmed M El-Assmy, Doaa Elsayed Sharaf, Mostafa Elgamal, Ahmed E Elzalouey, Mahmoud Laymon. A randomized trial of adjuvant tamsulosin as a medical expulsive therapy for renal stones after shock wave lithotripsy.
Urolithiasis.
2022 Aug; 50(4):473-480. doi:
10.1007/s00240-022-01330-5. [PMID: 35576073] - Mona M Abdel Moneim. Green & Sensitive pH-dependent Spectrofluorimetric Assay of Tamsulosin Hydrochloride and Tadalafil in their New Combined Formulation for Benign Prostatic Hyperplasia: Application to Spiked Human Plasma.
Journal of fluorescence.
2022 Jul; 32(4):1581-1590. doi:
10.1007/s10895-022-02938-x. [PMID: 35576092] - Chung Lyul Lee, Hyeun-Kyoo Shin, Ji Yong Lee, Ojin Kwon, Chang-Seob Seo, Ae-Ran Kim, Bok-Nam Seo, Seung Woo Yang, Ki Hak Song, Jae Sung Lim, Jong Mok Park, Yong Gil Na, Ju Hyun Shin. Combination therapy with tamsulosin and traditional herbal medicine for lower urinary tract symptoms due to benign prostatic hyperplasia: A double-blinded, randomized, pilot clinical trial.
International journal of urology : official journal of the Japanese Urological Association.
2022 06; 29(6):503-509. doi:
10.1111/iju.14821. [PMID: 35297106] - Abdulaziz Ahmed A Saad, Fan Zhang, Moath Refat, Eyad Abdulwhab H Mohammed, Mingkang Zhang, Yuyue Chen, Bandar Al Hamyari, Jameel Alafifi, Xin'an Wu. Tamsulosin alters the pharmacokinetics of metformin via inhibition of renal multidrug and toxin extrusion protein 1 and organic cation transporter 2 in rats.
Journal of pharmaceutical and biomedical analysis.
2022 Apr; 212(?):114666. doi:
10.1016/j.jpba.2022.114666. [PMID: 35183887] - Everardo Piñeyro-Garza, Magdalena Gómez-Silva, María E Gamino, Livan Delgado-Roche. Bioequivalence Assessment of an Oral Fixed-Dose Formulation of Dutasteride-Tamsulosin 0.5 mg/0.4 mg: A Randomized, Single-Blind, Single-Dose, 2-Period Crossover Study in Mexican Population Under Fasted Conditions.
Clinical pharmacology in drug development.
2022 03; 11(3):318-323. doi:
10.1002/cpdd.1011. [PMID: 34384000] - Rafael Edgardo Maldonado-Valadez, Angel David Valdez-Vargas, José Antonio Alvarez, Edel Rafael Rodea-Montero. Efficacy of Adjuvant Tamsulosin for Improving the Stone-Free Rate after Extracorporeal Shock Wave Lithotripsy in Renal Stones: A Randomized Controlled Trial.
International journal of clinical practice.
2022; 2022(?):3757588. doi:
10.1155/2022/3757588. [PMID: 35685573] - Ongart Sinsomboon, Patranuch Noppakulsatit, Adis Tassanarong, Parunkul Tungsukruthai, Kusuma Sriyakul. A Comparison of Effectiveness of Thai Traditional Massage and Tamsulosin in Lower Urinary Tract Symptoms: A Randomized Controlled Trial.
Journal of evidence-based integrative medicine.
2022 Jan; 27(?):2515690X211068825. doi:
10.1177/2515690x211068825. [PMID: 35001668] - Gianni Paulis, Andrea Paulis, Gianpaolo Perletti. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials.
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica.
2021 Dec; 93(4):475-480. doi:
10.4081/aiua.2021.4.475. [PMID: 34933534] - Lin Sun, Chengmin Sun, Shibo Zhou, Lan Zhang, Wenping Hu. Tamsulosin attenuates high glucose- induced injury in glomerular endothelial cells.
Bioengineered.
2021 12; 12(1):5184-5194. doi:
10.1080/21655979.2021.1955527. [PMID: 34402375] - Bahri Gok, Yavuz Tarik Atik, Burak Uysal, Erdem Koc, Sedat Tastemur, Haci İbrahim Cimen. Gilaburu extract (Viburnum opulus Linnaeus) is as effective as Tamsulosin in medical expulsive therapy of distal ureteral calculi.
International journal of clinical practice.
2021 Dec; 75(12):e14950. doi:
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Minerva urology and nephrology.
2021 12; 73(6):836-844. doi:
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BMC urology.
2021 Oct; 21(1):147. doi:
10.1186/s12894-021-00910-8. [PMID: 34666728] - Antonio Alcaraz, Alfredo Rodríguez-Antolín, Joaquín Carballido-Rodríguez, David Castro-Díaz, José Medina-Polo, Jesús M Fernández-Gómez, Vincenzo Ficarra, Joan Palou, Javier Ponce de León Roca, Javier C Angulo, Manuel Esteban-Fuertes, José M Cózar-Olmo, Noemí Pérez-León, José M Molero-García, Antonio Fernández-Pro Ledesma, Francisco J Brenes-Bermúdez, José Manasanch. Efficacy and tolerability of the hexanic extract of Serenoa repens compared to tamsulosin in moderate-severe LUTS-BPH patients.
Scientific reports.
2021 09; 11(1):19401. doi:
10.1038/s41598-021-98586-5. [PMID: 34588509] - Jianming Guo, Rong Tang. Efficacy and tolerability of doxazosin gastro-intestinal therapeutic system versus tamsulosin in patients with lower urinary tract symptoms associated with benign prostatic hyperplasia: A systematic review and meta-analysis.
Medicine.
2021 Aug; 100(33):e26955. doi:
10.1097/md.0000000000026955. [PMID: 34414962] - Shlomi Tapiero, Kamaljot S Kaler, Pengbo Jiang, Sherry Lu, Courtney Cottone, Roshan M Patel, Zhamshid Okhunov, Michael J Klopfer, Jaime Landman, Ralph V Clayman. Determining the Safety Threshold for the Passage of a Ureteral Access Sheath in Clinical Practice Using a Purpose-Built Force Sensor.
The Journal of urology.
2021 Aug; 206(2):364-372. doi:
10.1097/ju.0000000000001719. [PMID: 33780267] - Matthew S Lee, Mark Assmus, Deepak Agarwal, Marcelino E Rivera, Tim Large, Amy E Krambeck. Opioid Free Ureteroscopy: What is the True Failure Rate?.
Urology.
2021 08; 154(?):89-95. doi:
10.1016/j.urology.2021.03.011. [PMID: 33774043] - Allison Koenecke, Michael Powell, Ruoxuan Xiong, Zhu Shen, Nicole Fischer, Sakibul Huq, Adham M Khalafallah, Marco Trevisan, Pär Sparen, Juan J Carrero, Akihiko Nishimura, Brian Caffo, Elizabeth A Stuart, Renyuan Bai, Verena Staedtke, David L Thomas, Nickolas Papadopoulos, Ken W Kinzler, Bert Vogelstein, Shibin Zhou, Chetan Bettegowda, Maximilian F Konig, Brett D Mensh, Joshua T Vogelstein, Susan Athey. Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection.
eLife.
2021 06; 10(?):. doi:
10.7554/elife.61700. [PMID: 34114951] - Mohamed G Soliman, Shawky A El-Abd, Ahmed M Tawfik, Mohamed H Radwan, Ahmed S El-Abd. Efficacy and safety of mirabegron versus solifenacin as additional therapy for persistent OAB symptoms after tamsulosin monotherapy in men with probable BPO.
World journal of urology.
2021 Jun; 39(6):2049-2054. doi:
10.1007/s00345-020-03425-3. [PMID: 32869151] - Arcangelo Sebastianelli, Pietro Spatafora, Jacopo Frizzi, Omar Saleh, Cosimo De Nunzio, Andrea Tubaro, Linda Vignozzi, Mario Maggi, Sergio Serni, Kevin T McVary, Steven A Kaplan, Stavros Gravas, Christopher Chapple, Mauro Gacci. Which Drug to Discontinue 3 Months After Combination Therapy of Tadalafil plus Tamsulosin for Men with Lower Urinary Tract Symptom and Erectile Dysfunction? Results of a Prospective Observational Trial.
European urology focus.
2021 03; 7(2):432-439. doi:
10.1016/j.euf.2019.09.015. [PMID: 31606473] - Wei Ouyang, Guoliang Sun, Gongwei Long, Man Liu, Hua Xu, Zhiqiang Chen, Zhangqun Ye, Heng Li, Yucong Zhang. Adjunctive medical expulsive therapy with tamsulosin for repeated extracorporeal shock wave lithotripsy: a systematic review and meta-analysis.
International braz j urol : official journal of the Brazilian Society of Urology.
2021 Jan; 47(1):23-35. doi:
10.1590/s1677-5538.ibju.2020.0093. [PMID: 32459454] - Ebenezer Tunde Olayinka, Kayode Ezekiel Adewole. Ameliorative effect of morin on dutasteride-tamsulosin-induced testicular oxidative stress in rat.
Journal of complementary & integrative medicine.
2020 Dec; 18(2):327-337. doi:
10.1515/jcim-2019-0160. [PMID: 34187124] - Makinna C Oestreich, Robin Wm Vernooij, Niranjan J Sathianathen, Eu Chang Hwang, Gretchen M Kuntz, Alex Koziarz, Charles D Scales, Philipp Dahm. Alpha-blockers after shock wave lithotripsy for renal or ureteral stones in adults.
The Cochrane database of systematic reviews.
2020 11; 11(?):CD013393. doi:
10.1002/14651858.cd013393.pub2. [PMID: 33179245] - Huiwen Ren, Shengkai Zuo, Yayan Hou, Wenlong Shang, Na Liu, Zhuming Yin. Inhibition of α1-adrenoceptor reduces TGF-β1-induced epithelial-to-mesenchymal transition and attenuates UUO-induced renal fibrosis in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2020 11; 34(11):14892-14904. doi:
10.1096/fj.202000737rrr. [PMID: 32939891] - A Sebastianelli, P Spatafora, S Morselli, L Vignozzi, S Serni, K T McVary, S Kaplan, S Gravas, C Chapple, Mauro Gacci. Tadalafil Alone or in Combination with Tamsulosin for the Management for LUTS/BPH and ED.
Current urology reports.
2020 Oct; 21(12):56. doi:
10.1007/s11934-020-01009-7. [PMID: 33108544] - Noritoshi Sekido, Takeya Otsuki, Jun Kida, Hiroko Mashimo, Daisuke Wakamatsu, Hiroki Okada, Hidekazu Matsuya. EP2 and EP3 receptors as therapeutic targets for underactive bladder/detrusor underactivity due to diabetic cystopathy in a type 1 diabetic rat model.
Lower urinary tract symptoms.
2020 Sep; 12(3):285-291. doi:
10.1111/luts.12317. [PMID: 32410343] - Younghoon Jeon, Yehun Jin. Caudal block with steroid in the treatment of acute voiding dysfunction and pain caused by sacral herpes zoster: A case report.
Medicine.
2020 Jun; 99(25):e20680. doi:
10.1097/md.0000000000020680. [PMID: 32569199] - Santhosh Nagasubramanian, Nirmal Thampi John, Belavendra Antonisamy, Rajiv Paul Mukha, Chandra Singh Jeyachandra Berry, Santosh Kumar, Antony Devasia, Nitin Sudhakar Kekre. Tamsulosin and placebo vs tamsulosin and tadalafil in male lower urinary tract symptoms: a double-blinded, randomised controlled trial.
BJU international.
2020 05; 125(5):718-724. doi:
10.1111/bju.15027. [PMID: 32012409] - Gökhan Çeker. Is Serenoa repens Effective in the Treatment of Benign Prostatic Hyperplasia?.
American journal of men's health.
2020 May; 14(3):1557988320936897. doi:
10.1177/1557988320936897. [PMID: 32578492] - Boda Guo, Xin Chen, Miao Wang, Huimin Hou, Zhipeng Zhang, Ming Liu. Comparative Effectiveness of Tadalafil versus Tamsulosin in Treating Lower Urinary Tract Symptoms Suggestive of Benign Prostate Hyperplasia: A Meta-Analysis of Randomized Controlled Trials.
Medical science monitor : international medical journal of experimental and clinical research.
2020 Apr; 26(?):e923179. doi:
10.12659/msm.923179. [PMID: 32327621] - Ji-Sheng Wang, Jie Yang, Sheng Deng, Xu-Dong Yu, Bing-Hao Bao, Rui-Jia Liu, Hai-Song Li. Acupuncture combined with tamsulosin hydrochloride sustained-release capsule in the treatment of chronic prostatitis/chronic pelvic pain syndrome: A study protocol for a randomized controlled trial.
Medicine.
2020 Mar; 99(12):e19540. doi:
10.1097/md.0000000000019540. [PMID: 32195959] - Tong Cai, Yuanshan Cui, Shaoxia Yu, Qian Li, Zhongbao Zhou, Zhenli Gao. Comparison of Serenoa repens With Tamsulosin in the Treatment of Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis.
American journal of men's health.
2020 Mar; 14(2):1557988320905407. doi:
10.1177/1557988320905407. [PMID: 32274957] - Grzegorz Niemczyk, Lukasz Fus, Katarzyna Czarzasta, Anika Jesion, Piotr Radziszewski, Barbara Gornicka, Agnieszka Cudnoch-Jedrzejewska. Expression of Toll-Like Receptors in the Animal Model of Bladder Outlet Obstruction.
BioMed research international.
2020; 2020(?):6632359. doi:
10.1155/2020/6632359. [PMID: 33381567] - Krishnendu Maiti, Alankar Jaiswal, Dilip Kumar Pal. A comparative study of alpha-1a blockers (tamsulosin) versus estrogens in the treatment of lower urinary tract symptoms in perimenopausal females.
Indian journal of pharmacology.
2020 Jan; 52(1):6-9. doi:
10.4103/ijp.ijp_545_18. [PMID: 32201440] - Shunye Su, Jinlei Lin, Liqin Liang, Ludong Liu, Zhipeng Chen, Yuan Gao. The efficacy and safety of mirabegron on overactive bladder induced by benign prostatic hyperplasia in men receiving tamsulosin therapy: A systematic review and meta-analysis.
Medicine.
2020 Jan; 99(4):e18802. doi:
10.1097/md.0000000000018802. [PMID: 31977871] - Fabrizio Di Maida, Andrea Mari, Roberta Rubino, Andrea Minervini, Marco Carini, Giampaolo Siena. A Prospective, Open-Label Comparison of Tamsulosin plus Serenoa repens and Bovine Colostrum versus Tamsulosin Alone in the Treatment of Benign Prostatic Hyperplasia.
Urologia internationalis.
2020; 104(5-6):351-355. doi:
10.1159/000503735. [PMID: 31805571] - Shayara Lopes Ciríaco, Ivana Pereira Santos Carvalho, José Alves Terceiro Neto, José de Sousa Lima Neto, Daniel Henrique Bento de Oliveira, Ana Paula Gomes Pereira Cunha, Ykro Talvanis Duarte Cavalcante, Dayane Tomaz Casimiro da Silva, José Alexsandro da Silva, Ana Lys Bezerra Barradas Mineiro, Maria Zenaide de Lima Chagas Moreno Fernandes, André Luis Menezes Carvalho. Development of microemulsion of tamsulosin and dutasteride for benign prostatic hyperplasia therapy.
Colloids and surfaces. B, Biointerfaces.
2020 Jan; 185(?):110573. doi:
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Pakistan journal of pharmaceutical sciences.
2019 Nov; 32(6(Supplementary)):2779-2786. doi:
NULL. [PMID: 32024614] - Franklin C Lowe, Martin C Michel, Jan M Wruck, Anna E Verbeek. Is Dipstick Urinalysis Screening Beneficial in Men with Lower Urinary Tract Symptoms?.
Advances in therapy.
2019 10; 36(10):2954-2967. doi:
10.1007/s12325-019-01042-0. [PMID: 31392577] - Zhongbao Zhou, Xuesong Zheng, Jitao Wu, Zhenli Gao, Zhunan Xu, Yuanshan Cui. Meta-Analysis of Efficacy and Safety of Tadalafil Plus Tamsulosin Compared with Tadalafil Alone in Treating Men with Benign Prostatic Hyperplasia and Erectile Dysfunction.
American journal of men's health.
2019 Sep; 13(5):1557988319882597. doi:
10.1177/1557988319882597. [PMID: 31625449] - Bum Soo Kim, Tae-Hwan Kim, Ki Ho Kim, Byung Hoon Kim, Ji Yong Ha, Deok Hyun Cho, Gun Nam Kim, Yoon Hyung Lee, Jae Soo Kim, Hyun-Jin Jung, Hong Seok Shin, Phil Hyun Song, Jong Hyun Yoon, Jae Ho Kim, Eun Sang Yoo. Patient-reported Goal Achievement after Treating Male Benign Prostatic Hyperplasia with Alpha-adrenergic Antagonist: A 12-week Prospective Multicenter Study.
Urology journal.
2019 08; 16(4):386-391. doi:
10.22037/uj.v0i0.3784. [PMID: 30345500] - Ahmed S Safwat, Ahmad Hasanain, Ahmed Shahat, Mostafa AbdelRazek, Hazem Orabi, Samir K Abdul Hamid, Amany Nafee, Sally Bakkar, Mohamed Sayed. Cholecalciferol for the prophylaxis against recurrent urinary tract infection among patients with benign prostatic hyperplasia: a randomized, comparative study.
World journal of urology.
2019 Jul; 37(7):1347-1352. doi:
10.1007/s00345-018-2536-8. [PMID: 30361957] - Markos Karavitakis, Iason Kyriazis, Muhammad Imran Omar, Stavros Gravas, Jean-Nicolas Cornu, Marcus J Drake, Mauro Gacci, Christian Gratzke, Thomas R W Herrmann, Stephan Madersbacher, Malte Rieken, Mark J Speakman, Kari A O Tikkinen, Yuhong Yuan, Charalampos Mamoulakis. Management of Urinary Retention in Patients with Benign Prostatic Obstruction: A Systematic Review and Meta-analysis.
European urology.
2019 05; 75(5):788-798. doi:
10.1016/j.eururo.2019.01.046. [PMID: 30773327] - Andrew J Portis, Jennifer L Portis, Michael S Borofsky, Suzanne M Neises. Beyond medical expulsive therapy: evolution to supported stone passage for ureteric stones.
BJU international.
2019 04; 123(4):661-668. doi:
10.1111/bju.14491. [PMID: 30019368] - Kazuyuki Sakamoto, Yukiko Noguchi, Katsunori Imazumi, Koji Ueshima, Akiyoshi Ohtake, Masahiro Takeda, Noriyuki Masuda. ASP6432, a type 1 lysophosphatidic acid receptor antagonist, reduces urethral function during urine voiding and improves voiding dysfunction.
European journal of pharmacology.
2019 Mar; 847(?):83-90. doi:
10.1016/j.ejphar.2019.01.014. [PMID: 30658116] - Zhongbao Zhou, Yuanshan Cui, Jitao Wu, Rui Ding, Tong Cai, Zhenli Gao. Meta-analysis of the efficacy and safety of combination of tamsulosin plus dutasteride compared with tamsulosin monotherapy in treating benign prostatic hyperplasia.
BMC urology.
2019 Mar; 19(1):17. doi:
10.1186/s12894-019-0446-8. [PMID: 30871552] - Hiroshi Takahashi, Shinichi Kubono, Takehiko Taneyama, Kiyotoshi Kuramoto, Hideki Mizutani, Noriko Tanaka, Masaki Yoshida. Post-Marketing Surveillance of Silodosin in Patients with Benign Prostatic Hyperplasia and Poor Response to Existing Alpha-1 Blockers: The SPLASH Study.
Drugs in R&D.
2019 Mar; 19(1):47-55. doi:
10.1007/s40268-018-0258-4. [PMID: 30607819] - M I Walash, F Belal, M Fathy, S Zayed, H Borg. Simultaneous HPLC determination of alfuzosin, tamsulosin and vardenafil in human plasma and pharmaceutical formulations using time programmed fluorescence detection.
Annales pharmaceutiques francaises.
2019 Jan; 77(1):28-37. doi:
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BMC urology.
2018 Dec; 18(1):115. doi:
10.1186/s12894-018-0426-4. [PMID: 30545338] - Eu Chang Hwang, Shreyas Gandhi, Jae Hung Jung, Mari Imamura, Myung Ha Kim, Ran Pang, Philipp Dahm. Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia.
The Cochrane database of systematic reviews.
2018 10; 10(?):CD007360. doi:
10.1002/14651858.cd007360.pub3. [PMID: 30306544] - Jae Hoon Chung, Cheol Young Oh, Jae Heon Kim, U-Syn Ha, Tae Hyo Kim, Seung Hwan Lee, Jun Hyun Han, Jae Hyun Bae, In Ho Chang, Deok Hyun Han, Tag Keun Yoo, Jae Il Chung, Sae Woong Kim, Jina Jung, Yong-Il Kim, Seung Wook Lee. Efficacy and safety of tamsulosin 0.4 mg single pills for treatment of Asian patients with symptomatic benign prostatic hyperplasia with lower urinary tract symptoms: a randomized, double-blind, phase 3 trial.
Current medical research and opinion.
2018 10; 34(10):1793-1801. doi:
10.1080/03007995.2018.1447451. [PMID: 29490509] - Kyoung-Ah Kim, In-Bae Park, Ji-Young Park. Effects of CYP2D6 and CYP3A5 genetic polymorphisms on steady-state pharmacokinetics and hemodynamic effects of tamsulosin in humans.
European journal of clinical pharmacology.
2018 Oct; 74(10):1281-1289. doi:
10.1007/s00228-018-2501-x. [PMID: 29947950] - Marco Dellabella, Alessandro Branchi, Luca Gasparri, Redi Claudini, Daniele Castellani. Oncological safety and quality of life in men undergoing simultaneous transurethral resection of bladder tumor and prostate: results from a randomized controlled trial.
World journal of urology.
2018 Oct; 36(10):1629-1634. doi:
10.1007/s00345-018-2317-4. [PMID: 29725805] - Shohei Yoshida, Takahisa Noma, Kazuhisa Miyoshi, Hiroshi Tsukihara, Naoki Orimoto, Atsushi Hakozaki, Eiji Sasaki. Therapeutic effect of TAC-302, a cyclohexenoic fatty alcohol derivative, on bladder denervation-related storage and voiding dysfunctions in rats.
Neurourology and urodynamics.
2018 09; 37(7):2106-2113. doi:
10.1002/nau.23571. [PMID: 29635706] - Andrew J Portis, Matthew F Bultitude. Reply to the Reply to Andrew J. Portis and Matthew F. Bultitude's Letter to the Editor re: Zhangqun Ye, Guohua Zeng, Huan Yang, et al. Efficacy and Safety of Tamsulosin in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial. Eur Urol 2018;73:385-91.
European urology.
2018 08; 74(2):e42. doi:
10.1016/j.eururo.2018.04.013. [PMID: 29724501] - Andrew J Portis, Matthew F Bultitude. Re: Zhangqun Ye, Guohua Zeng, Huan Yang, et al. Efficacy and Safety of Tamsulosin in Medical Expulsive Therapy for Distal Ureteral Stones with Renal Colic: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial. Eur Urol 2018;73:385-91.
European urology.
2018 08; 74(2):e37-e39. doi:
10.1016/j.eururo.2018.02.009. [PMID: 29472142] - Güven Erbay, Ahmet Yalcın, Mehmet Hamza Gultekin. Predictor Role of Pretreatment Resistive and Pulsatile Indexes in the Success of Medical Expulsive Therapy of Ureteral Stones.
Urology.
2018 Aug; 118(?):47-51. doi:
10.1016/j.urology.2018.04.020. [PMID: 29729361] - Andrew C Meltzer, Pamela Katzen Burrows, Allan B Wolfson, Judd E Hollander, Michael Kurz, Ziya Kirkali, John W Kusek, Patrick Mufarrij, Stephen V Jackman, Jeremy Brown. Effect of Tamsulosin on Passage of Symptomatic Ureteral Stones: A Randomized Clinical Trial.
JAMA internal medicine.
2018 08; 178(8):1051-1057. doi:
10.1001/jamainternmed.2018.2259. [PMID: 29913020] - Kamaljot S Kaler, Egor Parkhomenko, Zhamshid Okunohov, Roshan M Patel, Jaime Landman, Ralph V Clayman, Carlos A Uribe. Ureteroscopic holmium laser-assisted retrograde nephrostomy access: a novel approach to percutaneous stone removal.
World journal of urology.
2018 Jun; 36(6):963-969. doi:
10.1007/s00345-018-2223-9. [PMID: 29423876] - Cheol-Hee Cho, Jin-Hong Min, Kyu-Mok Hwang, Eun-Seok Park. Development of sustained-release microparticles containing tamsulosin HCl for orally disintegrating tablet using melt-adsorption method.
Drug delivery and translational research.
2018 06; 8(3):552-564. doi:
10.1007/s13346-018-0477-9. [PMID: 29359246] - Olivia Burns, John Zhu, Michael J Manyak, Ramiya Ravindranath, Fariba Koosha, Nazneen Haque, Sally Chung. Relative Bioavailability of Fixed-Dose Combinations of Tamsulosin and Dutasteride: Results From 2 Randomized Trials in Healthy Male Volunteers.
Clinical pharmacology in drug development.
2018 05; 7(4):422-434. doi:
10.1002/cpdd.380. [PMID: 28800206] - Hamidreza Baghani Aval, Zeinab Ameli, Mojtaba Ameli. Effectiveness of the addition of tadalafil to tamsulosin in the treatment of acute urinary retention in patients with benign prostatic hyperplasia: A randomized clinical trial.
Urologia.
2018 May; 85(2):51-54. doi:
10.1177/0391560317749427. [PMID: 30043714] - D V Ergakov, A G Martov. [Combination therapy in the management of urinary disorders after transurethral resection of the prostate].
Urologiia (Moscow, Russia : 1999).
2018 Mar; ?(1):62-70. doi:
NULL. [PMID: 29634136] - Bo Ram Choi, Hye Kyung Kim, Kiran Kumar Soni, Keshab Kumar Karna, Sung Won Lee, Insuk So, Jong Kwan Park. Additive effect of oral LDD175 to tamsulosin and finasteride in a benign prostate hyperplasia rat model.
Drug design, development and therapy.
2018; 12(?):1855-1863. doi:
10.2147/dddt.s164049. [PMID: 29970959] - Lisette Haddad, Stéphanie Corriveau, Eric Rousseau, Simon Blouin, Jean-Charles Pasquier, Yves Ponsot, Marie-Ève Roy-Lacroix. Impact of tamsulosin and nifedipine on contractility of pregnant rat ureters in vitro.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.
2018 Jan; 31(2):191-196. doi:
10.1080/14767058.2017.1280017. [PMID: 28068846] - Oscar Luis Farelo-Trejos, Nahuel Eduardo Paesano, Juan José Serna-Hurtado, Mauro Fabián García, Juan Ignacio Monzó-Gardiner. [Prognostic factors predicting failure of the trial without catheter after tamsulosin in patients with acute urinary retention.].
Archivos espanoles de urologia.
2017 Nov; 70(9):759-765. doi:
NULL. [PMID: 29099378] - Jonathan S Ellison, Paul A Merguerian, Benjamin C Fu, Sarah K Holt, Thomas S Lendvay, John L Gore, Margarett Shnorhavorian. Use of medical expulsive therapy in children: An assessment of nationwide practice patterns and outcomes.
Journal of pediatric urology.
2017 Oct; 13(5):509.e1-509.e7. doi:
10.1016/j.jpurol.2017.03.022. [PMID: 28483465] - B U Shalekenov, Y A Kuandykov, S B Shalekenov. [Effectiveness of Omnic and Omnic Ocas in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia (multi-center observing program)].
Urologiia (Moscow, Russia : 1999).
2017 Oct; ?(5):42-47. doi:
10.18565/urology.2017.5.42-47. [PMID: 29135141] - A V Govorov, A O Vasilyev, D Yu Pushkar. [Efficacy of tamsulosin for treating lower urinary tract symptoms in patients with advanced prostate cancer].
Urologiia (Moscow, Russia : 1999).
2017 Sep; ?(4):37-41. doi:
. [PMID: 28952690] - Renee Kurczewski, Chet Bowen, David Collins, John Zhu, Gulyeter Serbest, Michael Manyak. Bioequivalence Studies of a Reformulated Dutasteride and Tamsulosin Hydrochloride Combination Capsule and a Commercially Available Formulation.
Clinical pharmacology in drug development.
2017 Sep; 6(5):508-516. doi:
10.1002/cpdd.334. [PMID: 28127948] - Miao Yan, Peng Xue, Kunpeng Wang, Guojun Gao, Wei Zhang, Fanghu Sun. Does combination therapy with tamsulosin and trospium chloride improve lower urinary tract symptoms after SEEDS brachytherapy for prostate cancer compared with tamsulosin alone? : A prospective, randomized, controlled trial.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al].
2017 Sep; 193(9):714-721. doi:
10.1007/s00066-017-1162-5. [PMID: 28612083] - Xiang Fei, Wei Jin, Shengyu Hua, Yan Song. Prospective Study on Association of Prostatic Calcifications with Clinical Symptoms and Results of Treatment in Men with type III prostatitis.
Scientific reports.
2017 07; 7(1):5234. doi:
10.1038/s41598-017-05550-3. [PMID: 28701725] - Ruwen Zheng, Hui Hu. [Impacts of electroacupuncture on benign prostatic hyperplasia and the levels of estrogen and androgen in patients].
Zhongguo zhen jiu = Chinese acupuncture & moxibustion.
2017 Jun; 37(6):599-602. doi:
10.13703/j.0255-2930.2017.06.007. [PMID: 29231500] - John Roger Bell, Kristina L Penniston, Sara L Best, Stephen Y Nakada. A survey of patient preferences regarding medical expulsive therapy following the SUSPEND trial.
The Canadian journal of urology.
2017 Jun; 24(3):8827-8831. doi:
NULL. [PMID: 28646938] - Yaser Pashaei, Fatemeh Ghorbani-Bidkorbeh, Maryam Shekarchi. Superparamagnetic graphene oxide-based dispersive-solid phase extraction for preconcentration and determination of tamsulosin hydrochloride in human plasma by high performance liquid chromatography-ultraviolet detection.
Journal of chromatography. A.
2017 May; 1499(?):21-29. doi:
10.1016/j.chroma.2017.03.038. [PMID: 28410800] - Sonal Gupta, Deepti Pandey, Dhanaraju Mandalapu, Vikas Sharma, Mahendra Shukla, Seema Singh, Nidhi Singh, Santosh Kumar Yadav, Dilip Kumar Tanpula, Surabhi Singh, Jagdamba P Maikhuri, Shubha Shukla, Jawahar Lal, Mohammad I Siddiqi, Gopal Gupta, Vishnu L Sharma. Novel aryl piperazines for alleviation of 'andropause' associated prostatic disorders and depression.
European journal of medicinal chemistry.
2017 May; 132(?):204-218. doi:
10.1016/j.ejmech.2017.03.036. [PMID: 28363155] - M Kennedy Hall, Mathew Sorenson, Jonathan Harper. Should Kidney Stone Patients With Diagnosis by Ultrasonography Be Prescribed Tamsulosin?.
Annals of emergency medicine.
2017 04; 69(4):523-524. doi:
10.1016/j.annemergmed.2016.11.044. [PMID: 28335927] - Da-Lin Sun, Bin Cai, Bao-Fang Jin, Guo-Shou Xia, Zhi-An Tang, Wen-Tao Yang, Qiang Zou, Guo-Hong Song, Jian-Guo Liu, Hong-le Zhao, Ning Dai, Jia-Hui Wang, Ya-Long Gu, Ya-Lin Zhai. [Bushen Daozhuo Granules for type Ⅲ prostatitis: A multicenter randomized controlled clinical trial].
Zhonghua nan ke xue = National journal of andrology.
2017 Feb; 23(2):164-168. doi:
". [PMID: 29658256] - Pamela K Burrows, Judd E Hollander, Allan B Wolfson, Michael C Kurz, Lorna Richards, Sara DiFiore, Phillip Watts, Nivedita Patkar, Jeremy Brown, Stephen Jackman, Ziya Kirkali, John W Kusek, Chloe Michel, Andrew C Meltzer. Design and challenges of a randomized clinical trial of medical expulsive therapy (tamsulosin) for urolithiasis in the emergency department.
Contemporary clinical trials.
2017 01; 52(?):91-94. doi:
10.1016/j.cct.2016.11.010. [PMID: 27890522] - Fen Wei, Sicen Wang, Nan Lv, Yusi Bu, Xiaoyu Xie. Characterization the affinity of α1A adrenoreceptor by cell membrane chromatography with frontal analysis and stoichiometric displacement model.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Jan; 1040(?):273-281. doi:
10.1016/j.jchromb.2016.11.002. [PMID: 27836488] - A G Martov, D V Ergakov. [Age-related androgen deficiency and benign prostatic hyperplasia: how to improve the rehabilitation of patients after transurethral surgery?].
Urologiia (Moscow, Russia : 1999).
2016 Dec; ?(6):110-117. doi:
NULL. [PMID: 28248054] - Naoki Wada, Hiromichi Iuchi, Masafumi Kita, Kazumi Hashizume, Seiji Matsumoto, Hidehiro Kakizaki. Urodynamic Efficacy and Safety of Mirabegron Add-on Treatment with Tamsulosin for Japanese Male Patients with Overactive Bladder.
Lower urinary tract symptoms.
2016 Sep; 8(3):171-6. doi:
10.1111/luts.12091. [PMID: 27619782] - Steven A Kaplan. Re: Comparison of Tamsulosin plus Serenoa repens with Tamsulosin in the Treatment of Benign Prostatic Hyperplasia in Korean Men: 1-Year Randomized Open Label Study.
The Journal of urology.
2016 08; 196(2):503. doi:
10.1016/j.juro.2016.05.021. [PMID: 27479407] - Noriaki Utsunomiya, Keiyu Matsumoto, Hiroyuki Tsunemori, Koei Muguruma, Mutsushi Kawakita, Yuki Kamiyama, Sojun Kanamaru, Noriyuki Ito, Hideki Tsukazaki, Toshiaki Shirahase, Takeshi Takahashi. [A Crossover Comparison Study on Lower Urinary Tract Symptoms with Overactive Bladder Secondary to Benign Prostatic Hyperplasia: Naftopidil versus Tamsulosin with Solifenacin].
Hinyokika kiyo. Acta urologica Japonica.
2016 Jul; 62(7):341-7. doi:
10.14989/actauroljap_62_7_341. [PMID: 27569351] - Cosimo De Nunzio, Aldo Brassetti, Mariangela Bellangino, Alberto Trucchi, Stefano Petta, Fabrizio Presicce, Andrea Tubaro. Tamsulosin or Silodosin Adjuvant Treatment Is Ineffective in Improving Shockwave Lithotripsy Outcome: A Short-Term Follow-Up Randomized, Placebo-Controlled Study.
Journal of endourology.
2016 07; 30(7):817-21. doi:
10.1089/end.2016.0113. [PMID: 27080916] - Robert Chan, Alvaro Munoz, Evan P Wenker, Melissa Whipple, Brian Miles, Timothy B Boone. Solifenacin and Tamsulosin Combination Therapy Decreases Urine Nerve Growth Factor/Creatinine Levels in Men.
Urology.
2016 05; 91(?):150-3. doi:
10.1016/j.urology.2016.01.020. [PMID: 26829718] - Antonio Alcaraz, Joaquín Carballido-Rodríguez, Miguel Unda-Urzaiz, Rafael Medina-López, José L Ruiz-Cerdá, Federico Rodríguez-Rubio, Darío García-Rojo, Francisco J Brenes-Bermúdez, José M Cózar-Olmo, Víctor Baena-González, José Manasanch. Quality of life in patients with lower urinary tract symptoms associated with BPH: change over time in real-life practice according to treatment--the QUALIPROST study.
International urology and nephrology.
2016 May; 48(5):645-56. doi:
10.1007/s11255-015-1206-7. [PMID: 26810324] - Ahmed Shahat, Ahmad Elderwy, Ahmed S Safwat, Islam F Abdelkawi, Ahmed Reda, Yasser Abdelsalam, Mohamed Sayed, Hisham Hammouda. Is Tamsulosin Effective after Shock Wave Lithotripsy for Pediatric Renal Stones? A Randomized, Controlled Study.
The Journal of urology.
2016 Apr; 195(4 Pt 2):1284-8. doi:
10.1016/j.juro.2015.11.021. [PMID: 26926538] - Bo Ram Choi, Kiran Kumar Soni, Li Tao Zhang, Sung Won Lee, Insuk So, Hye Kyung Kim, Jong Kwan Park. Effect of 4-chloro-7-trifluoromethyl-10H-benzo[4,5]furo[3,2-b]indole-1-carboxylic acid on the intraurethral pressure in a rat model of benign prostatic hyperplasia.
International journal of urology : official journal of the Japanese Urological Association.
2016 Mar; 23(3):259-65. doi:
10.1111/iju.13018. [PMID: 26646436] - Glenn M Preminger, John Roger Bell, Stephen Y Nakada. Medical Expulsive Therapy is Useful for Urinary Calculi.
The Journal of urology.
2016 Mar; 195(3):554-6. doi:
10.1016/j.juro.2015.12.066. [PMID: 26690572] - Sri Sivalingam, Necole M Streeper, Priyanka D Sehgal, Brian C Sninsky, Sara L Best, Stephen Y Nakada. Does Combination Therapy with Tamsulosin and Tolterodine Improve Ureteral Stent Discomfort Compared with Tamsulosin Alone? A Double-Blind, Randomized, Controlled Trial.
The Journal of urology.
2016 Feb; 195(2):385-90. doi:
10.1016/j.juro.2015.08.104. [PMID: 26393904] - Abul-Fotouh Ahmed. Sonographic Parameters Predicting the Outcome of Patients With Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia Treated With Alpha1-Adrenoreceptor Antagonist.
Urology.
2016 Feb; 88(?):143-8. doi:
10.1016/j.urology.2015.11.017. [PMID: 26607685] - Abul-Fotouh Ahmed, Essam Shalaby, Mohamed El-Feky, Ayman Kotb, Ebrahim Elsotohi, Mohamed El-Kholy, Ahmed Ragab, Emad Salem. Role of Tamsulosin Therapy after Extracorporeal Shockwave Lithotripsy for Renal Stones: Randomized Controlled Trial.
Urologia internationalis.
2016; 97(3):266-272. doi:
10.1159/000445840. [PMID: 27082108] - Alain Latil, Marie-Thérèse Pétrissans, Jérôme Rouquet, Grégoire Robert, Alexandre de la Taille. Effects of hexanic extract of Serenoa repens (Permixon® 160 mg) on inflammation biomarkers in the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia.
The Prostate.
2015 Dec; 75(16):1857-67. doi:
10.1002/pros.23059. [PMID: 26306400] - Jun Wang, Yang Xiao, Zhi-gang Wang, Feng-feng Wang, Xue-jiao Cui. [Combination therapy of Xipayimaizipizi Capsules and Tamsulosin for benign prostatic hyperplasia].
Zhonghua nan ke xue = National journal of andrology.
2015 Nov; 21(11):1005-9. doi:
NULL. [PMID: 26738328] - Blayne Welk, Eric McArthur, Lisa-Ann Fraser, Jade Hayward, Stephanie Dixon, Y Joseph Hwang, Michael Ordon. The risk of fall and fracture with the initiation of a prostate-selective α antagonist: a population based cohort study.
BMJ (Clinical research ed.).
2015 Oct; 351(?):h5398. doi:
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