Tamsulosin (BioDeep_00001867818)
Main id: BioDeep_00000002542
代谢物信息卡片
化学式: C20H28N2O5S (408.17188380000005)
中文名称: 坦索罗辛
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOC1=CC=CC=C1OCCNC(C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N
InChI: InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1
描述信息
G - Genito urinary system and sex hormones > G04 - Urologicals > G04C - Drugs used in benign prostatic hypertrophy > G04CA - Alpha-adrenoreceptor antagonists
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists
D000089162 - Genitourinary Agents > D064804 - Urological Agents
Tamsulosin ((R)-(-)-YM12617 free base) is an inhibitor of α1-adrenergic receptor. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth in animal models[1].
同义名列表
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:9398
- KEGG: C07124
- KEGGdrug: D08560
- PubChem: 129211
- DrugBank: DB00706
- ChEMBL: CHEMBL836
- MeSH: Tamsulosin
- CAS: 106133-20-4
- PubChem: 9334
- PDB-CCD: JGX
- NIKKAJI: J340.699G
- RefMet: Tamsulosin
- medchemexpress: HY-B0661
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Hong-Ping Shen, Jing-Xian Xu, Li Wang, Zhi-Bo Zheng, Yi Yu, Ke-Qi Zhu, Xue-Qin Chen. [Simiaotongzhuo Decoction for the treatment of type III prostatitis: A clinical observation].
Zhonghua nan ke xue = National journal of andrology.
2023 Apr; 29(4):348-352. doi:
"
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BMC cardiovascular disorders.
2023 Mar; 23(1):153. doi:
10.1186/s12872-023-03188-w
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Drug delivery.
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Urolithiasis.
2022 Aug; 50(4):473-480. doi:
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Journal of fluorescence.
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International journal of clinical practice.
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Journal of evidence-based integrative medicine.
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International journal of clinical practice.
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Minerva urology and nephrology.
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BMC urology.
2021 Oct; 21(1):147. doi:
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Scientific reports.
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Medicine.
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eLife.
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World journal of urology.
2021 Jun; 39(6):2049-2054. doi:
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European urology focus.
2021 03; 7(2):432-439. doi:
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International braz j urol : official journal of the Brazilian Society of Urology.
2021 Jan; 47(1):23-35. doi:
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. [PMID: 32459454] - Ebenezer Tunde Olayinka, Kayode Ezekiel Adewole. Ameliorative effect of morin on dutasteride-tamsulosin-induced testicular oxidative stress in rat.
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The Cochrane database of systematic reviews.
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
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Lower urinary tract symptoms.
2020 Sep; 12(3):285-291. doi:
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Medicine.
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BJU international.
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American journal of men's health.
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. [PMID: 32578492] - Boda Guo, Xin Chen, Miao Wang, Huimin Hou, Zhipeng Zhang, Ming Liu. Comparative Effectiveness of Tadalafil versus Tamsulosin in Treating Lower Urinary Tract Symptoms Suggestive of Benign Prostate Hyperplasia: A Meta-Analysis of Randomized Controlled Trials.
Medical science monitor : international medical journal of experimental and clinical research.
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. [PMID: 32327621] - Ji-Sheng Wang, Jie Yang, Sheng Deng, Xu-Dong Yu, Bing-Hao Bao, Rui-Jia Liu, Hai-Song Li. Acupuncture combined with tamsulosin hydrochloride sustained-release capsule in the treatment of chronic prostatitis/chronic pelvic pain syndrome: A study protocol for a randomized controlled trial.
Medicine.
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American journal of men's health.
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BioMed research international.
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Indian journal of pharmacology.
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Medicine.
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Urologia internationalis.
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Colloids and surfaces. B, Biointerfaces.
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Pakistan journal of pharmaceutical sciences.
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Advances in therapy.
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American journal of men's health.
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European urology.
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BJU international.
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European journal of pharmacology.
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BMC urology.
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Drugs in R&D.
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. [PMID: 30172351] - Zhigang Xue, Yunhua Lin, Yongguang Jiang, Nengbao Wei, Jinwen Bi. The evaluation of nocturia in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia and the analysis of the curative effect after medical or placebo therapy for nocturia: a randomized placebo-controlled study.
BMC urology.
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The Cochrane database of systematic reviews.
2018 10; 10(?):CD007360. doi:
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Current medical research and opinion.
2018 10; 34(10):1793-1801. doi:
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European journal of clinical pharmacology.
2018 Oct; 74(10):1281-1289. doi:
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World journal of urology.
2018 Oct; 36(10):1629-1634. doi:
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Neurourology and urodynamics.
2018 09; 37(7):2106-2113. doi:
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European urology.
2018 08; 74(2):e42. doi:
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European urology.
2018 08; 74(2):e37-e39. doi:
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Urology.
2018 Aug; 118(?):47-51. doi:
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JAMA internal medicine.
2018 08; 178(8):1051-1057. doi:
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World journal of urology.
2018 Jun; 36(6):963-969. doi:
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Drug delivery and translational research.
2018 06; 8(3):552-564. doi:
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Clinical pharmacology in drug development.
2018 05; 7(4):422-434. doi:
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Urologia.
2018 May; 85(2):51-54. doi:
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Urologiia (Moscow, Russia : 1999).
2018 Mar; ?(1):62-70. doi:
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Drug design, development and therapy.
2018; 12(?):1855-1863. doi:
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The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.
2018 Jan; 31(2):191-196. doi:
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Archivos espanoles de urologia.
2017 Nov; 70(9):759-765. doi:
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Journal of pediatric urology.
2017 Oct; 13(5):509.e1-509.e7. doi:
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Urologiia (Moscow, Russia : 1999).
2017 Oct; ?(5):42-47. doi:
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Urologiia (Moscow, Russia : 1999).
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Clinical pharmacology in drug development.
2017 Sep; 6(5):508-516. doi:
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Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al].
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Scientific reports.
2017 07; 7(1):5234. doi:
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Zhongguo zhen jiu = Chinese acupuncture & moxibustion.
2017 Jun; 37(6):599-602. doi:
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The Canadian journal of urology.
2017 Jun; 24(3):8827-8831. doi:
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2017 May; 1499(?):21-29. doi:
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European journal of medicinal chemistry.
2017 May; 132(?):204-218. doi:
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Annals of emergency medicine.
2017 04; 69(4):523-524. doi:
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Zhonghua nan ke xue = National journal of andrology.
2017 Feb; 23(2):164-168. doi:
"
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Contemporary clinical trials.
2017 01; 52(?):91-94. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Jan; 1040(?):273-281. doi:
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Urologiia (Moscow, Russia : 1999).
2016 Dec; ?(6):110-117. doi:
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Lower urinary tract symptoms.
2016 Sep; 8(3):171-6. doi:
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The Journal of urology.
2016 08; 196(2):503. doi:
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Hinyokika kiyo. Acta urologica Japonica.
2016 Jul; 62(7):341-7. doi:
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Journal of endourology.
2016 07; 30(7):817-21. doi:
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Urology.
2016 05; 91(?):150-3. doi:
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International urology and nephrology.
2016 May; 48(5):645-56. doi:
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The Journal of urology.
2016 Apr; 195(4 Pt 2):1284-8. doi:
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International journal of urology : official journal of the Japanese Urological Association.
2016 Mar; 23(3):259-65. doi:
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The Journal of urology.
2016 Mar; 195(3):554-6. doi:
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The Journal of urology.
2016 Feb; 195(2):385-90. doi:
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Urology.
2016 Feb; 88(?):143-8. doi:
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Urologia internationalis.
2016; 97(3):266-272. doi:
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The Prostate.
2015 Dec; 75(16):1857-67. doi:
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Zhonghua nan ke xue = National journal of andrology.
2015 Nov; 21(11):1005-9. doi:
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BMJ (Clinical research ed.).
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