Medrysone (BioDeep_00000858525)

Main id: BioDeep_00000002730

 


代谢物信息卡片


11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione

化学式: C22H32O3 (344.2351)
中文名称: 6α-甲基-11β-羟基孕酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)CC4)C)O)C)C(=O)C
InChI: InChI=1S/C22H32O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h10,12,15-17,19-20,25H,5-9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BA - Corticosteroids, plain
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
Same as: D02289

同义名列表

3 个代谢物同义名

11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione; Medrysone; Medrysone



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ARHGAP45, CAT, CDKN1C, DNMT3A, GADD45G, GPI, KHDC3L, NLRP7, PADI6
Nucleus 9 APCS, CDKN1C, DNMT3A, GADD45G, KHDC3L, MCM7, NANOG, PADI6, RUNX1
cytosol 4 ARHGAP45, CAT, GPI, MCM7
centrosome 1 KHDC3L
nucleoplasm 5 CD2, DNMT3A, MCM7, NANOG, RUNX1
Cell membrane 3 CD2, CD8A, TNF
ruffle membrane 1 ARHGAP45
cell cortex 1 KHDC3L
cell surface 2 CD2, TNF
Golgi apparatus 2 ATRN, CD2
neuronal cell body 1 TNF
plasma membrane 5 ARHGAP45, ATRN, CD2, CD8A, TNF
Membrane 4 ARHGAP45, CAT, GPI, MCM7
extracellular exosome 5 APCS, ATRN, CAT, GPI, TIMP1
extracellular space 5 APCS, ATRN, GPI, TIMP1, TNF
mitochondrion 2 CAT, KHDC3L
protein-containing complex 3 CAT, CD2, KHDC3L
intracellular membrane-bounded organelle 3 CAT, NANOG, RUNX1
Single-pass type I membrane protein 3 ATRN, CD2, CD8A
Secreted 4 APCS, GPI, PRB1, TIMP1
extracellular region 9 APCS, ARHGAP45, CAT, CD2, CD8A, GPI, PRB1, TIMP1, TNF
cytoplasmic side of plasma membrane 1 CD2
[Isoform 2]: Secreted 2 ATRN, CD8A
mitochondrial matrix 1 CAT
ciliary membrane 1 GPI
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 KHDC3L
external side of plasma membrane 3 CD2, CD8A, TNF
nucleolus 1 NANOG
cell-cell junction 1 CD2
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cell projection, ruffle membrane 1 ARHGAP45
heterochromatin 1 DNMT3A
Membrane raft 1 TNF
focal adhesion 1 CAT
extracellular matrix 1 TIMP1
Peroxisome 1 CAT
basement membrane 1 TIMP1
collagen trimer 1 TIMP1
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 APCS
receptor complex 1 CD8A
chromatin 3 MCM7, NANOG, RUNX1
phagocytic cup 1 TNF
Chromosome 3 DNMT3A, KHDC3L, MCM7
chromosome, telomeric region 1 MCM7
Cytoplasm, cell cortex 1 KHDC3L
blood microparticle 1 APCS
subcortical maternal complex 1 KHDC3L
[Isoform 3]: Secreted 1 ATRN
euchromatin 1 DNMT3A
intermediate filament cytoskeleton 1 PADI6
plasma membrane raft 1 CD8A
ficolin-1-rich granule lumen 2 CAT, GPI
secretory granule lumen 3 ARHGAP45, CAT, GPI
endoplasmic reticulum lumen 1 TIMP1
nuclear matrix 1 DNMT3A
platelet alpha granule lumen 1 TIMP1
XY body 1 DNMT3A
azurophil granule lumen 1 ARHGAP45
chromosome, centromeric region 1 DNMT3A
[Isoform 1]: Cell membrane 2 ATRN, CD8A
CMG complex 1 MCM7
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD8A
catalase complex 1 CAT
catalytic complex 1 DNMT3A
Cytoplasmic vesicle, secretory vesicle, Cortical granule 1 PADI6
cortical granule 1 PADI6
MCM complex 1 MCM7
core-binding factor complex 1 RUNX1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Zheng-yu Qin, Hu Ling, Xiao-hong Xia, Li Meng, Zi-jian Wu. [Effects of electroacupuncture of Sanyinjiao (SP 6) on genito-endocrine in patients with perimenopausal syndrome]. Zhen ci yan jiu = Acupuncture research. 2007 Aug; 32(4):255-9. doi: NULL. [PMID: 17907389]
  • N L Verbey, N J van Haeringen, P T de Jong. The effects of 3-isobutyl-methyl-xanthine on experimentally induced ocular inflammation in the rabbit. Current eye research. 1988 Jun; 7(6):557-61. doi: 10.3109/02713688809031811. [PMID: 2456895]