farnesyl diphosphate (BioDeep_00000638402)

Main id: BioDeep_00000001707

 

PANOMIX_OTCML-2023 natural product Volatile Flavor Compounds


代谢物信息卡片


2-trans,6-trans-Farnesyl diphosphate

化学式: C15H28O7P2 (382.1310198)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=CCC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)C
InChI: InChI=1S/C15H28O7P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18/h7,9,11H,5-6,8,10,12H2,1-4H3,(H,19,20)(H2,16,17,18)/b14-9+,15-11+

描述信息

The trans,trans-stereoisomer of farnesyl diphosphate.

同义名列表

4 个代谢物同义名

2-trans,6-trans-Farnesyl diphosphate; farnesyl diphosphate; Farnesyl pyrophosphate; trans,trans-Farnesyl diphosphate



数据库引用编号

16 个数据库交叉引用编号

分类词条

54 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sung Chul Park, Breanne N Steffan, Fang Yun Lim, Raveena Gupta, Fatma Ayaloglu Butun, Hongyu Chen, Rosa Ye, Timothy Decker, Chengcang C Wu, Neil L Kelleher, Jin Woo Bok, Nancy P Keller. Terpenoid balance in Aspergillus nidulans unveiled by heterologous squalene synthase expression. Science advances. 2024 Feb; 10(8):eadk7416. doi: 10.1126/sciadv.adk7416. [PMID: 38381828]
  • Xuan Song, Chang Liu, Khalid H Dhiloo, Chao-Qun Yi, Tian-Tao Zhang, Yong-Jun Zhang. Functional characterization of a geranylgeranyl diphosphate synthase in the leaf beetle Monolepta hieroglyphica. Archives of insect biochemistry and physiology. 2024 Feb; 115(2):e22088. doi: 10.1002/arch.22088. [PMID: 38349673]
  • Hayat Hage, Julie Couillaud, Asaf Salamov, Margot Loussouarn-Yvon, Fabien Durbesson, Elena Ormeño, Sacha Grisel, Katia Duquesne, Renaud Vincentelli, Igor Grigoriev, Gilles Iacazio, Marie-Noëlle Rosso. An HMM approach expands the landscape of sesquiterpene cyclases across the kingdom Fungi. Microbial genomics. 2023 Apr; 9(4):. doi: 10.1099/mgen.0.000990. [PMID: 37073784]
  • Jing Chen, Jing Tan, Xinyu Duan, Ying Wang, Jing Wen, Wei Li, Zhengguo Li, Guodong Wang, Haiyang Xu. Plastidial engineering with coupled farnesyl diphosphate pool reconstitution and enhancement for sesquiterpene biosynthesis in tomato fruit. Metabolic engineering. 2023 Mar; 77(?):41-52. doi: 10.1016/j.ymben.2023.03.002. [PMID: 36893914]
  • Liliane Sena Pinheiro, Valter Viana Andrade-Neto, Marcio Mantuano-Barradas, Elisa Cavalcante Pereira, Rodrigo Cesar Fernandes Barbosa, Marcia Cristina Campos de Oliveira, Rubem Figueiredo Sadok Menna-Barreto, Edézio Ferreira Cunha-Júnior, Eduardo Caio Torres-Santos. Biological effects of trans, trans-farnesol in Leishmania amazonensis. Frontiers in cellular and infection microbiology. 2023; 13(?):1221246. doi: 10.3389/fcimb.2023.1221246. [PMID: 38035328]
  • Cuicui Yu, Shixi Gao, Mei Rong, Mengjun Xiao, Yanhong Xu, Jianhe Wei. Identification and characterization of novel sesquiterpene synthases TPS9 and TPS12 from Aquilaria sinensis. PeerJ. 2023; 11(?):e15818. doi: 10.7717/peerj.15818. [PMID: 37663295]
  • Hoang V Tang, David L Berryman, Jorrel Mendoza, Jessica P Yactayo-Chang, Qin-Bao Li, Shawn A Christensen, Charles T Hunter, Norman Best, Eric Soubeyrand, Tariq A Akhtar, Gilles J Basset, Anna K Block. Dedicated farnesyl diphosphate synthases circumvent isoprenoid-derived growth-defense tradeoffs in Zea mays. The Plant journal : for cell and molecular biology. 2022 10; 112(1):207-220. doi: 10.1111/tpj.15941. [PMID: 35960639]
  • Nur Suhanawati Ashaari, Mohd Hairul Ab Rahim, Suriana Sabri, Kok Song Lai, Adelene Ai-Lian Song, Raha Abdul Rahim, Janna Ong Abdullah. Kinetic studies and homology modeling of a dual-substrate linalool/nerolidol synthase from Plectranthus amboinicus. Scientific reports. 2021 08; 11(1):17094. doi: 10.1038/s41598-021-96524-z. [PMID: 34429465]
  • Jianxun Zhu, Lihong Liu, Maobo Wu, Guiyang Xia, Pengcheng Lin, Jiachen Zi. Characterization of a Sesquiterpene Synthase Catalyzing Formation of Cedrol and Two Diastereoisomers of Tricho-Acorenol from Euphorbia fischeriana. Journal of natural products. 2021 06; 84(6):1780-1786. doi: 10.1021/acs.jnatprod.1c00126. [PMID: 34014675]
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  • Şükrü Tüzmen, Galen Hostetter, Aprill Watanabe, Cumhur Ekmekçi, Patricia E Carrigan, Ishaiahu Shechter, Olli Kallioniemi, Laurence J Miller, Spyro Mousses. Characterization of farnesyl diphosphate farnesyl transferase 1 (FDFT1) expression in cancer. Personalized medicine. 2019 01; 16(1):51-65. doi: 10.2217/pme-2016-0058. [PMID: 30468409]
  • Yashpal S Chhonker, Staci L Haney, Veenu Bala, Sarah A Holstein, Daryl J Murry. Simultaneous Quantitation of Isoprenoid Pyrophosphates in Plasma and Cancer Cells Using LC-MS/MS. Molecules (Basel, Switzerland). 2018 Dec; 23(12):. doi: 10.3390/molecules23123275. [PMID: 30544938]
  • Sholeem Griffin, Gareth D Healey, I Martin Sheldon. Isoprenoids increase bovine endometrial stromal cell tolerance to the cholesterol-dependent cytolysin from Trueperella pyogenes. Biology of reproduction. 2018 10; 99(4):749-760. doi: 10.1093/biolre/ioy099. [PMID: 29688258]
  • Jason Lancaster, Ashot Khrimian, Sharon Young, Bryan Lehner, Katrin Luck, Anna Wallingford, Saikat Kumar B Ghosh, Philipp Zerbe, Andrew Muchlinski, Paul E Marek, Michael E Sparks, James G Tokuhisa, Claus Tittiger, Tobias G Köllner, Donald C Weber, Dawn E Gundersen-Rindal, Thomas P Kuhar, Dorothea Tholl. De novo formation of an aggregation pheromone precursor by an isoprenyl diphosphate synthase-related terpene synthase in the harlequin bug. Proceedings of the National Academy of Sciences of the United States of America. 2018 09; 115(37):E8634-E8641. doi: 10.1073/pnas.1800008115. [PMID: 30139915]
  • Xi Zhang, Tianyang Guo, Tong Xiang, Yiyang Dong, Jichuan Zhang, Liqun Zhang. Quantitation of isoprenoids for natural rubber biosynthesis in natural rubber latex by liquid chromatography with tandem mass spectrometry. Journal of chromatography. A. 2018 Jul; 1558(?):115-119. doi: 10.1016/j.chroma.2018.05.006. [PMID: 29773339]
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  • Zhaojun Shen, Saisai Li, Bo Sheng, Qi Shen, Lu-Zhe Sun, Haiyan Zhu, Xueqiong Zhu. The role of atorvastatin in suppressing tumor growth of uterine fibroids. Journal of translational medicine. 2018 03; 16(1):53. doi: 10.1186/s12967-018-1430-x. [PMID: 29523174]
  • Sheila McCormick. Unilateral incompatibility is linked to reduced pollen expression of a farnesyl pyrophosphate synthase. The Plant journal : for cell and molecular biology. 2018 02; 93(3):415-416. doi: 10.1111/tpj.13814. [PMID: 29352523]
  • Wenhua Tan, Stefan Bartram, Wilhelm Boland. Mechanistic studies of sesquiterpene cyclases based on their carbon isotope ratios at natural abundance. Plant, cell & environment. 2018 Jan; 41(1):39-49. doi: 10.1111/pce.12901. [PMID: 28045196]
  • Jun-Ichiro Hattan, Kazutoshi Shindo, Tetsuya Sasaki, Norihiko Misawa. Isolation and Functional Characterization of New Terpene Synthase Genes from Traditional Edible Plants. Journal of oleo science. 2018; 67(10):1235-1246. doi: 10.5650/jos.ess18163. [PMID: 30305556]
  • Pavel Mikulecky, Elena Andreeva, Patricia Amara, Winfried Weissenhorn, Yvain Nicolet, Pauline Macheboeuf. Human viperin catalyzes the modification of GPP and FPP potentially affecting cholesterol synthesis. FEBS letters. 2018 01; 592(2):199-208. doi: 10.1002/1873-3468.12941. [PMID: 29251770]
  • Lixia Yang, Liangzhen Jiang, Wei Li, Yun Yang, Guolin Zhang, Yinggang Luo. A homomeric geranyl diphosphate synthase-encoding gene from Camptotheca acuminata and its combinatorial optimization for production of geraniol in Escherichia coli. Journal of industrial microbiology & biotechnology. 2017 Oct; 44(10):1431-1441. doi: 10.1007/s10295-017-1967-3. [PMID: 28695386]
  • Miho Takemura, Rie Tanaka, Norihiko Misawa. Pathway engineering for the production of β-amyrin and cycloartenol in Escherichia coli-a method to biosynthesize plant-derived triterpene skeletons in E. coli. Applied microbiology and biotechnology. 2017 Sep; 101(17):6615-6625. doi: 10.1007/s00253-017-8409-z. [PMID: 28710558]
  • Hiroyuki Kajiura, Nobuaki Suzuki, Yuji Tokumoto, Takuya Yoshizawa, Shinya Takeno, Kazuhito Fujiyama, Yoshinobu Kaneko, Hiroyoshi Matsumura, Yoshihisa Nakazawa. Two Eucommia farnesyl diphosphate synthases exhibit distinct enzymatic properties leading to end product preferences. Biochimie. 2017 Aug; 139(?):95-106. doi: 10.1016/j.biochi.2017.05.001. [PMID: 28478108]
  • Yating Hu, Yongjin J Zhou, Jichen Bao, Luqi Huang, Jens Nielsen, Anastasia Krivoruchko. Metabolic engineering of Saccharomyces cerevisiae for production of germacrene A, a precursor of beta-elemene. Journal of industrial microbiology & biotechnology. 2017 07; 44(7):1065-1072. doi: 10.1007/s10295-017-1934-z. [PMID: 28547322]
  • Hiroshi Sugimoto, Mie Iguchi, Fumihiro Jinno. Bioanalysis of farnesyl pyrophosphate in human plasma by high-performance liquid chromatography coupled to triple quadrupole tandem mass spectrometry and hybrid quadrupole Orbitrap high-resolution mass spectrometry. Analytical and bioanalytical chemistry. 2017 May; 409(14):3551-3560. doi: 10.1007/s00216-017-0293-y. [PMID: 28343347]
  • Vít Kosek, Milena Stránská, Marie Fenclová, Tomáš Ruml, Libor Vítek, Jana Hajšlová. High resolution mass spectrometry based method applicable for a wide range of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors in blood serum including intermediates and products of the cholesterol biosynthetic pathway. Journal of chromatography. A. 2017 Mar; 1489(?):86-94. doi: 10.1016/j.chroma.2017.01.084. [PMID: 28209347]
  • Jieying Qian, Yong Liu, Naixia Chao, Chengtong Ma, Qicong Chen, Jian Sun, Yaosheng Wu. Positive selection and functional divergence of farnesyl pyrophosphate synthase genes in plants. BMC molecular biology. 2017 02; 18(1):3. doi: 10.1186/s12867-017-0081-4. [PMID: 28160774]
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