Tubocurarine (BioDeep_00000422649)

Main id: BioDeep_00000003814

 

natural product


代谢物信息卡片


Tubocurarine

化学式: C37H41N2O6+ (609.2964)
中文名称: D-筒箭毒碱
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C6C(CC7=CC(=C(C=C7)O)O3)[N+](CCC6=CC(=C5O)OC)(C)C)OC
InChI: InChI=1S/C37H40N2O6/c1-38-14-12-24-19-32(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-37-35-25(20-34(43-5)36(37)41)13-15-39(2,3)29(35)17-23-8-11-30(40)31(18-23)45-33/h6-11,18-21,28-29H,12-17H2,1-5H3,(H-,40,41)/p+1/t28-,29+/m0/s1

描述信息

M - Musculo-skeletal system > M03 - Muscle relaxants > M03A - Muscle relaxants, peripherally acting agents > M03AA - Curare alkaloids
D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents > D009466 - Neuromuscular Blocking Agents
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists
A benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare.

同义名列表

2 个代谢物同义名

Tubocurarine; Tubocurarine



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ABCB1, AKT1, AXIN2, BCL2, BDNF, CASP3, CAT, CHAT, NOS2, PTGS2
Peripheral membrane protein 2 ACHE, PTGS2
Endoplasmic reticulum membrane 3 BCL2, HMOX1, PTGS2
Nucleus 8 ACHE, AKT1, AXIN2, BCL2, CASP3, CHAT, HMOX1, NOS2
cytosol 8 AKT1, AXIN2, BCL2, CASP3, CAT, CHAT, HMOX1, NOS2
dendrite 1 BDNF
centrosome 1 AXIN2
nucleoplasm 4 AKT1, CASP3, HMOX1, NOS2
Cell membrane 5 ABCB1, ACHE, AKT1, HTR3A, TNF
Cytoplasmic side 1 HMOX1
Cleavage furrow 1 HTR3A
lamellipodium 1 AKT1
Multi-pass membrane protein 3 ABCB1, HTR3A, KCNA3
Synapse 4 ACHE, CHAT, HTR3A, TAC1
cell cortex 1 AKT1
cell surface 3 ABCB1, ACHE, TNF
glutamatergic synapse 3 AKT1, CASP3, KCNA3
Golgi apparatus 1 ACHE
Golgi membrane 1 INS
neuromuscular junction 1 ACHE
neuronal cell body 3 CASP3, TAC1, TNF
postsynapse 2 AKT1, HTR3A
presynaptic membrane 1 KCNA3
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 1 NOS2
plasma membrane 10 ABCB1, ACHE, AKT1, AXIN2, BCHE, HTR3A, IGHE, KCNA3, NOS2, TNF
Membrane 9 ABCB1, ACHE, AKT1, BCL2, BDNF, CAT, HMOX1, HTR3A, KCNA3
apical plasma membrane 1 ABCB1
axon 3 BDNF, KCNA3, TAC1
caveola 1 PTGS2
extracellular exosome 2 ABCB1, CAT
endoplasmic reticulum 3 BCL2, HMOX1, PTGS2
extracellular space 9 ACHE, BCHE, BDNF, HMOX1, IGHE, IL6, INS, TAC1, TNF
perinuclear region of cytoplasm 5 ACHE, BDNF, HMOX1, KCNA3, NOS2
mitochondrion 2 BCL2, CAT
protein-containing complex 4 AKT1, BCL2, CAT, PTGS2
intracellular membrane-bounded organelle 1 CAT
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 IGHE
Secreted 5 ACHE, BCHE, BDNF, IL6, INS
extracellular region 9 ACHE, BCHE, BDNF, CAT, IGHE, IL6, INS, TAC1, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
beta-catenin destruction complex 1 AXIN2
microtubule cytoskeleton 1 AKT1
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
postsynaptic membrane 2 HTR3A, KCNA3
Apical cell membrane 1 ABCB1
Cytoplasm, perinuclear region 1 NOS2
Membrane raft 2 KCNA3, TNF
pore complex 1 BCL2
focal adhesion 1 CAT
spindle 1 AKT1
Peroxisome 2 CAT, NOS2
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, NOS2
peroxisomal membrane 1 CAT
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Postsynaptic cell membrane 1 HTR3A
neuron projection 3 CHAT, HTR3A, PTGS2
ciliary basal body 1 AKT1
IgE immunoglobulin complex 1 IGHE
phagocytic cup 1 TNF
blood microparticle 1 BCHE
serotonin-activated cation-selective channel complex 1 HTR3A
transmembrane transporter complex 1 HTR3A
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 2]: Cell membrane 2 IGHE, KCNA3
endosome lumen 1 INS
side of membrane 1 ACHE
myelin sheath 1 BCL2
voltage-gated potassium channel complex 1 KCNA3
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 5 BCHE, BDNF, IL6, INS, PTGS2
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
nuclear envelope lumen 1 BCHE
calyx of Held 1 KCNA3
synaptic cleft 1 ACHE
external side of apical plasma membrane 1 ABCB1
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cell membrane 1 KCNA3
[Isoform 3]: Cell membrane 1 IGHE
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
cortical cytoskeleton 1 NOS2
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
[Isoform 3]: Cytoplasm, perinuclear region 1 KCNA3
[Isoform H]: Cell membrane 1 ACHE
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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