Azamethiphos (BioDeep_00000408774)

Main id: BioDeep_00000003968

 


代谢物信息卡片


Azamethiphos

化学式: C9H10ClN2O5PS (323.9737)
中文名称: 甲基吡啶磷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COP(=O)(OC)SCN(C(=O)1)c(n2)c(cc(Cl)c2)O1
InChI: InChI=1S/C9H10ClN2O5PS/c1-15-18(14,16-2)19-5-12-8-7(17-9(12)13)3-6(10)4-11-8/h3-4H,5H2,1-2H3

描述信息

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents

同义名列表

2 个代谢物同义名

Azamethiphos; Azamethiphos



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ALB, BCL2L1, CNOT3, CNOT7, GAP43, GPX1, GSTP1, HSPA8, MYLK, PKM
Peripheral membrane protein 4 ACHE, CYP1B1, GAP43, HSPA8
Endoplasmic reticulum membrane 1 CYP1B1
Mitochondrion membrane 1 BCL2L1
Nucleus 9 ACHE, ALB, CNOT3, CNOT7, CS, GSTP1, HSPA8, MANF, PKM
autophagosome 1 HSPA8
cytosol 11 ALB, BCL2L1, CNOT3, CNOT7, GPX1, GSTP1, HSPA8, MANF, MYLK, NGF, PKM
dendrite 2 GAP43, NGF
nuclear body 1 CNOT7
centrosome 2 ALB, BCL2L1
nucleoplasm 1 HSPA8
Cell membrane 3 ACHE, ATP1A1, GAP43
Cytoplasmic side 3 BCL2L1, GAP43, HSPA8
Cleavage furrow 1 MYLK
lamellipodium 1 MYLK
Cell projection, axon 2 ATP1A1, GAP43
Multi-pass membrane protein 1 ATP1A1
Synapse 3 ACHE, GAP43, MYLK
cell surface 3 ACHE, CR1, HSPA8
dendritic shaft 1 HSPA8
glutamatergic synapse 1 HSPA8
Golgi apparatus 3 ACHE, ALB, ATP1A1
lysosomal membrane 1 HSPA8
mitochondrial inner membrane 1 BCL2L1
neuromuscular junction 1 ACHE
sarcolemma 1 ATP1A1
synaptic vesicle 2 HSPA8, NGF
Cytoplasm, cytosol 1 BCL2L1
Presynapse 1 GAP43
plasma membrane 7 ACHE, ATP1A1, BCHE, CR1, GAP43, HSPA8, MYLK
synaptic vesicle membrane 1 BCL2L1
terminal bouton 1 HSPA8
Membrane 7 ACHE, ATP1A1, CNOT7, CR1, CS, CYP1B1, HSPA8
apical plasma membrane 1 ATP1A1
axon 2 ATP1A1, NGF
basolateral plasma membrane 1 ATP1A1
extracellular exosome 8 ALB, ATP1A1, CR1, CS, GSTP1, HSPA8, PKM, SOD2
Lysosome membrane 1 HSPA8
endoplasmic reticulum 4 ALB, ATP1A1, BCL2L1, MANF
extracellular space 8 ACHE, ALB, BCHE, CR1, GSTP1, HSPA8, MANF, NGF
lysosomal lumen 1 HSPA8
perinuclear region of cytoplasm 2 ACHE, HSPA8
mitochondrion 7 BCL2L1, CS, CYP1B1, GPX1, GSTP1, PKM, SOD2
protein-containing complex 2 ALB, ATP1A1
intracellular membrane-bounded organelle 1 CYP1B1
Microsome membrane 1 CYP1B1
postsynaptic density 3 ATP1A1, GAP43, HSPA8
Secreted 5 ACHE, ALB, BCHE, MANF, NGF
extracellular region 8 ACHE, ALB, BCHE, GSTP1, HSPA8, MANF, NGF, PKM
Mitochondrion outer membrane 1 BCL2L1
Single-pass membrane protein 1 BCL2L1
mitochondrial outer membrane 1 BCL2L1
Mitochondrion matrix 3 BCL2L1, CS, SOD2
mitochondrial matrix 4 BCL2L1, CS, GPX1, SOD2
Extracellular side 1 ACHE
anchoring junction 1 ALB
photoreceptor inner segment 1 HSPA8
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 BCL2L1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 BCL2L1
Nucleus membrane 1 BCL2L1
Bcl-2 family protein complex 1 BCL2L1
nuclear membrane 1 BCL2L1
Extracellular vesicle 2 ATP1A1, PKM
actin cytoskeleton 1 MYLK
dendritic spine 1 HSPA8
sodium:potassium-exchanging ATPase complex 1 ATP1A1
T-tubule 1 ATP1A1
perikaryon 2 GAP43, HSPA8
nucleolus 1 HSPA8
Cytoplasm, P-body 2 CNOT3, CNOT7
P-body 2 CNOT3, CNOT7
vesicle 2 GSTP1, PKM
Cell membrane, sarcolemma 1 ATP1A1
Cell projection, lamellipodium 1 MYLK
Membrane raft 1 ATP1A1
focal adhesion 1 HSPA8
microtubule 1 HSPA8
GABA-ergic synapse 1 GAP43
mitochondrial nucleoid 1 SOD2
basement membrane 1 ACHE
collagen-containing extracellular matrix 1 PKM
intermediate filament 1 HSPA8
lateral plasma membrane 1 ATP1A1
nuclear speck 1 CNOT7
Late endosome 1 HSPA8
ciliary basal body 1 ALB
cilium 1 PKM
cytoskeleton 1 CR1
centriole 1 ALB
Nucleus, nucleolus 1 HSPA8
spindle pole 1 ALB
blood microparticle 3 ALB, BCHE, HSPA8
CCR4-NOT complex 2 CNOT3, CNOT7
CCR4-NOT core complex 2 CNOT3, CNOT7
Basolateral cell membrane 1 ATP1A1
Lipid-anchor, GPI-anchor 1 ACHE
spliceosomal complex 1 HSPA8
organelle membrane 1 ATP1A1
sperm flagellum 1 ATP1A1
endosome lumen 1 NGF
Cell projection, dendrite 1 GAP43
Melanosome 2 ATP1A1, HSPA8
side of membrane 1 ACHE
filopodium membrane 1 GAP43
stress fiber 1 MYLK
plasma membrane raft 1 CR1
ficolin-1-rich granule lumen 3 GSTP1, HSPA8, PKM
secretory granule lumen 3 GSTP1, HSPA8, PKM
secretory granule membrane 1 CR1
Golgi lumen 1 NGF
endoplasmic reticulum lumen 3 ALB, BCHE, MANF
platelet alpha granule lumen 1 ALB
Photoreceptor inner segment membrane 1 ATP1A1
nuclear envelope lumen 1 BCHE
Sarcoplasmic reticulum lumen 1 MANF
Cytoplasm, cytoskeleton, stress fiber 1 MYLK
ribonucleoprotein complex 1 HSPA8
protein folding chaperone complex 1 HSPA8
synaptic cleft 1 ACHE
Cytoplasm, Cytoplasmic ribonucleoprotein granule 1 CNOT7
ficolin-1-rich granule membrane 1 CR1
postsynaptic specialization membrane 1 HSPA8
intracellular non-membrane-bounded organelle 1 CNOT7
Rough endoplasmic reticulum 1 PKM
Prp19 complex 1 HSPA8
Cell projection, filopodium membrane 1 GAP43
glycinergic synapse 1 HSPA8
TRAF2-GSTP1 complex 1 GSTP1
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane 1 HSPA8
lumenal side of lysosomal membrane 1 HSPA8
lysosomal matrix 1 HSPA8
photoreceptor ribbon synapse 1 HSPA8
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
Cell projection, growth cone membrane 1 GAP43
growth cone membrane 1 GAP43
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB
[Isoform Bcl-X(L)]: Mitochondrion inner membrane 1 BCL2L1


文献列表

  • Mercedes María Noel Reynoso, Emilia Ana Seccacini, Eduardo Nicolás Zerba, Raúl Adolfo Alzogaray. Botanical monoterpenes synergise the toxicity of azamethiphos in the vector of Chagas disease, Triatoma infestans (Hemiptera: Reduviidae). Tropical medicine & international health : TM & IH. 2020 12; 25(12):1480-1485. doi: 10.1111/tmi.13488. [PMID: 32945539]
  • Josip Barisic, Stuart Cannon, Brian Quinn. Cumulative impact of anti-sea lice treatment (azamethiphos) on health status of Rainbow trout (Oncorhynchus mykiss, Walbaum 1792) in aquaculture. Scientific reports. 2019 11; 9(1):16217. doi: 10.1038/s41598-019-52636-1. [PMID: 31700034]
  • C M Couillard, L E Burridge. Sublethal exposure to azamethiphos causes neurotoxicity, altered energy allocation and high mortality during simulated live transport in American lobster. Ecotoxicology and environmental safety. 2015 May; 115(?):291-9. doi: 10.1016/j.ecoenv.2014.11.016. [PMID: 25499691]
  • Mabruka H Tarhoni, Timothy Lister, David E Ray, Wayne G Carter. Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2008 Jun; 13(4):343-63. doi: 10.1080/13547500801973563. [PMID: 18484351]
  • Rita Romani, Ilaria Corsi, Stefano Bonacci, Silvano Focardi, G Evelina De Medio, Alessandra De Santis, Francesca Incarnato, Elvio Giovannini, Gabriella Rosi. Organophosphate-resistant forms of acetylcholinesterases in two scallops--the Antarctic Adamussium colbecki and the Mediterranean Pecten jacobaeus. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2006 Oct; 145(2):188-96. doi: 10.1016/j.cbpb.2006.07.005. [PMID: 16931084]
  • M C Fossi, C Leonzio, A Massi, L Lari, S Casini. Serum esterase inhibition in birds: a nondestructive biomarker to assess organophosphorus and carbamate contamination. Archives of environmental contamination and toxicology. 1992 Jul; 23(1):99-104. doi: 10.1007/bf00226001. [PMID: 1637204]