verruculogen (BioDeep_00000408572)
Main id: BioDeep_00000003934
natural product
代谢物信息卡片
化学式: C27H33N3O7 (511.2318)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(plant) 8.99%
分子结构信息
SMILES: CC(=CC1N2C3=C(C=CC(=C3)OC)C4=C2C(CC(OO1)(C)C)N5C(=O)C6CCCN6C(=O)C5(C4O)O)C
InChI: InChI=1S/C27H33N3O7/c1-14(2)11-20-29-18-12-15(35-5)8-9-16(18)21-22(29)19(13-26(3,4)37-36-20)30-24(32)17-7-6-10-28(17)25(33)27(30,34)23(21)31/h8-9,11-12,17,19-20,23,31,34H,6-7,10,13H2,1-5H3/t17-,19-,20+,23-,27+/m0/s1
描述信息
An organic heterohexacyclic compound that is a mycotoxic indole alkaloid isolated from Penicillium and Aspergillus species.
CONFIDENCE Penicillium amphipolaria
同义名列表
1 个代谢物同义名
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:72765
- KEGG: C20045
- PubChem: 13887805
- ChEMBL: CHEMBL551369
- MoNA: AC000756
- MoNA: AC000755
- MoNA: AC000754
- MoNA: AC000753
- MoNA: AC000752
- MetaboLights: MTBLC72765
- PubChem: 135626511
- KNApSAcK: C00011299
- CAS: 12771-72-1
- PDB-CCD: 8H5
- LOTUS: LTS0225904
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
57 个相关的物种来源信息
- 4890 - Ascomycota: LTS0225904
- 1131492 - Aspergillaceae: LTS0225904
- 5052 - Aspergillus: LTS0225904
- 176165 - Aspergillus caespitosus: 10.1016/B978-0-12-179760-7.50023-1
- 36630 - Aspergillus fischeri: 10.1128/AEM.54.6.1504-1510.1988
- 36630 - Aspergillus fischeri: LTS0225904
- 746128 - Aspergillus fumigatus:
- 746128 - Aspergillus fumigatus: 10.1016/0031-9422(90)80080-Z
- 746128 - Aspergillus fumigatus: 10.1021/JF300146N
- 746128 - Aspergillus fumigatus: 10.1021/NP800700E
- 746128 - Aspergillus fumigatus: 10.7164/ANTIBIOTICS.49.527
- 746128 - Aspergillus fumigatus: 10.7164/ANTIBIOTICS.49.534
- 746128 - Aspergillus fumigatus: LTS0225904
- 75750 - Aspergillus sydowii: 10.1021/NP700737G
- 75750 - Aspergillus sydowii: LTS0225904
- 45847 - Cordyceps tenuipes: 10.1021/NP800702C
- 2759 - Eukaryota: LTS0225904
- 147545 - Eurotiomycetes: LTS0225904
- 4751 - Fungi: LTS0225904
- 36629 - Neosartorya: LTS0225904
- 5073 - Penicillium: LTS0225904
- 104259 - Penicillium brasilianum: 10.1016/B978-0-12-179760-7.50024-3
- 104259 - Penicillium brasilianum: 10.1021/JA00828A054
- 104259 - Penicillium brasilianum: LTS0225904
- 1295095 - Penicillium estinogenum: 10.1002/BIT.260271111
- 1295095 - Penicillium estinogenum: 10.1021/JA00828A054
- 1295095 - Penicillium estinogenum: LTS0225904
- 197659 - Penicillium glandicola: 10.1016/B978-0-12-179760-7.50024-3
- 197659 - Penicillium glandicola: 10.1021/JA00828A054
- 197659 - Penicillium glandicola: LTS0225904
- 545233 - Penicillium ianthinellum: 10.1016/B978-0-12-179760-7.50024-3
- 5079 - Penicillium janthinellum: 10.1016/B978-0-12-179760-7.50024-3
- 5079 - Penicillium janthinellum: 10.1021/JA00828A054
- 5079 - Penicillium janthinellum: LTS0225904
- 69779 - Penicillium melinii:
- 69779 - Penicillium melinii: 10.1128/AEM.51.4.821-824.1986
- 69779 - Penicillium melinii: LTS0225904
- 434487 - Penicillium novae-zeelandiae: 10.1128/AEM.51.4.821-824.1986
- 434487 - Penicillium novae-zeelandiae: LTS0225904
- 104260 - Penicillium paraherquei: 10.1021/JA00828A054
- 104260 - Penicillium paraherquei: LTS0225904
- 70109 - Penicillium paxilli: 10.1021/NP50005A017
- 70109 - Penicillium paxilli: LTS0225904
- 104167 - Penicillium piscarium: 10.1021/JA00828A054
- 104167 - Penicillium piscarium: LTS0225904
- 69488 - Penicillium simplicissimum:
- 69488 - Penicillium simplicissimum: 10.1021/JA00828A054
- 69488 - Penicillium simplicissimum: 10.1128/AEM.51.4.821-824.1986
- 69488 - Penicillium simplicissimum: 10.1271/BBB.58.334
- 69488 - Penicillium simplicissimum: LTS0225904
- 5094 - Talaromyces: LTS0225904
- 198730 - Talaromyces verruculosus:
- 198730 - Talaromyces verruculosus: 10.1021/JA00828A054
- 198730 - Talaromyces verruculosus: 10.1039/C39930000274
- 198730 - Talaromyces verruculosus: 10.3987/S-1982-01-0349
- 198730 - Talaromyces verruculosus: LTS0225904
- 28568 - Trichocomaceae: LTS0225904
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Pei-Chun Chen, Jing-Syuna Ruan, Sheng-Nan Wu. Evidence of Decreased Activity in Intermediate-Conductance Calcium-Activated Potassium Channels During Retinoic Acid-Induced Differentiation in Motor Neuron-Like NSC-34 Cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2018; 48(6):2374-2388. doi:
10.1159/000492653. [PMID: 30114691] - Khaled Khoufache, Olivier Puel, Nicolas Loiseau, Marcel Delaforge, Danièle Rivollet, André Coste, Catherine Cordonnier, Estelle Escudier, Françoise Botterel, Stéphane Bretagne. Verruculogen associated with Aspergillus fumigatus hyphae and conidia modifies the electrophysiological properties of human nasal epithelial cells.
BMC microbiology.
2007 Jan; 7(?):5. doi:
10.1186/1471-2180-7-5. [PMID: 17244350] - Regina M Geris dos Santos, Edson Rodrigues-Fo. Meroterpenes from Penicillium sp found in association with Melia azedarach.
Phytochemistry.
2002 Dec; 61(8):907-12. doi:
10.1016/s0031-9422(02)00379-5. [PMID: 12453515] - I Laws, P G Mantle, L Rodrigues, R H Penny. Fate of TR-2, the hepatic metabolite of the tremorgenic mycotoxin verruculogen, in sheep.
Xenobiotica; the fate of foreign compounds in biological systems.
1987 Aug; 17(8):973-9. doi:
10.3109/00498258709044196. [PMID: 3673112] - K P Perera, P G Mantle, R H Penny. Metabolism and excretion of [14C] verruculogen in a sheep.
Research in veterinary science.
1982 May; 32(3):347-50. doi:
. [PMID: 7100651]
