diclofenac (BioDeep_00000405802)

Main id: BioDeep_00000001459

 


代谢物信息卡片


diclofenac

化学式: C14H11Cl2NO2 (295.0167)
中文名称: 2-(2,6-二氯苯氨基)苯乙酸, 双氯芬酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl
InChI: InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)

描述信息

M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain > M02AA - Antiinflammatory preparations, non-steroids for topical use
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AB - Acetic acid derivatives and related substances
S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BC - Antiinflammatory agents, non-steroids
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor
D000893 - Anti-Inflammatory Agents
D004791 - Enzyme Inhibitors
D - Dermatologicals

同义名列表

3 个代谢物同义名

diclofenac; Diclofenac; Diclofenac



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ABCB1, CYP2C8, CYP2D6, CYP3A4, PPARG, PTGS1, PTGS2, VEGFA
Peripheral membrane protein 3 GORASP1, PTGS1, PTGS2
Endoplasmic reticulum membrane 6 CYP2C8, CYP2D6, CYP3A4, PTGS1, PTGS2, UGT2B7
Nucleus 3 MPO, PPARG, VEGFA
cytosol 3 ATP12A, IL1B, PPARG
nucleoplasm 2 MPO, PPARG
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 1 ABCB1
Cytoplasmic side 1 GORASP1
Multi-pass membrane protein 5 ABCB1, ABCC2, ATP12A, CACNA1I, KCNA3
Golgi apparatus membrane 1 GORASP1
Synapse 1 TAC1
cell surface 3 ABCB1, ABCC2, VEGFA
glutamatergic synapse 1 KCNA3
Golgi apparatus 3 GORASP1, PTGS1, VEGFA
Golgi membrane 1 GORASP1
neuronal cell body 1 TAC1
presynaptic membrane 1 KCNA3
Cytoplasm, cytosol 1 IL1B
Lysosome 2 IL1B, MPO
plasma membrane 8 ABCB1, ABCC2, ATP12A, CACNA1I, CYP2C8, IGHE, KCNA3, REN
Membrane 9 ABCB1, ABCC2, CACNA1I, CYP2D6, CYP3A4, KCNA3, REN, UGT2B7, VEGFA
apical plasma membrane 3 ABCB1, ABCC2, ATP12A
axon 2 KCNA3, TAC1
basolateral plasma membrane 1 ATP12A
caveola 1 PTGS2
extracellular exosome 3 ABCB1, MPO, PTGS1
endoplasmic reticulum 3 CYP2D6, PTGS2, VEGFA
extracellular space 7 IGHE, IL10, IL1B, MPO, REN, TAC1, VEGFA
perinuclear region of cytoplasm 2 KCNA3, PPARG
adherens junction 1 VEGFA
intercellular canaliculus 1 ABCC2
mitochondrion 1 CYP2D6
protein-containing complex 1 PTGS2
intracellular membrane-bounded organelle 6 CYP2C8, CYP2D6, CYP3A4, MPO, PPARG, PTGS1
Microsome membrane 4 CYP2D6, CYP3A4, PTGS1, PTGS2
Single-pass type I membrane protein 1 IGHE
Secreted 4 IL10, IL1B, REN, VEGFA
extracellular region 7 IGHE, IL10, IL1B, MPO, REN, TAC1, VEGFA
Single-pass membrane protein 2 CYP2D6, UGT2B7
photoreceptor outer segment 1 PTGS1
Secreted, extracellular space, extracellular matrix 1 VEGFA
actin cytoskeleton 1 ATP12A
apical part of cell 1 REN
postsynaptic membrane 1 KCNA3
Apical cell membrane 3 ABCB1, ABCC2, ATP12A
Membrane raft 1 KCNA3
cis-Golgi network 1 GORASP1
extracellular matrix 1 VEGFA
secretory granule 3 IL1B, MPO, VEGFA
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 1 PPARG
neuron projection 2 PTGS1, PTGS2
chromatin 1 PPARG
IgE immunoglobulin complex 1 IGHE
[Isoform 2]: Cell membrane 2 IGHE, KCNA3
Endomembrane system 1 PTGS1
azurophil granule 1 MPO
voltage-gated potassium channel complex 1 KCNA3
endoplasmic reticulum lumen 1 PTGS2
platelet alpha granule lumen 1 VEGFA
voltage-gated calcium channel complex 1 CACNA1I
Secreted, extracellular exosome 1 IL1B
azurophil granule lumen 1 MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
calyx of Held 1 KCNA3
phagocytic vesicle lumen 1 MPO
external side of apical plasma membrane 1 ABCB1
[Isoform 1]: Cell membrane 1 KCNA3
[Isoform 3]: Cell membrane 1 IGHE
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
potassium:proton exchanging ATPase complex 1 ATP12A
[Isoform 3]: Cytoplasm, perinuclear region 1 KCNA3


文献列表

  • Karthikeyan Kandaswamy, Ajay Guru, Siva Prasad Panda, Anahas Perianaika Matharasi Antonyraj, Zulhisyam Abdul Kari, Jayant Giri, Bader O Almutairi, Selvaraj Arokiyaraj, Guilherme Malafaia, Jesu Arockiaraj. Polystyrene nanoplastics synergistically exacerbate diclofenac toxicity in embryonic development and the health of adult zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2024 Jul; 281(?):109926. doi: 10.1016/j.cbpc.2024.109926. [PMID: 38641085]
  • Klaudia Kwidzińska, Martyna Zalewska, Anna Aksmann, Justyna Kobos, Hanna Mazur-Marzec, Magda Caban. Multi-biomarker response of cyanobacteria Synechocystis salina and Microcystis aeruginosa to diclofenac. Journal of hazardous materials. 2024 Jun; 471(?):134373. doi: 10.1016/j.jhazmat.2024.134373. [PMID: 38678710]
  • Stephan Schmidt, Holger Hoffmann, Leif-Alexander Garbe, Andrea Harrer, Markus Steiner, Martin Himly, Rudolf J Schneider. Re-assessment of monoclonal antibodies against diclofenac for their application in the analysis of environmental waters. Analytical methods : advancing methods and applications. 2024 May; 16(21):3349-3363. doi: 10.1039/d3ay01333b. [PMID: 38742423]
  • Georgios Paraskevopoulos, Ferdinand Fandrei, Ajit Kumar Pratihast, Anna Paraskevopoulou, Eleni Panoutsopoulou, Lukáš Opálka, Venus Singh Mithu, Daniel Huster, Kateřina Vávrová. Effects of imidazolium ionic liquids on skin barrier lipids - Perspectives for drug delivery. Journal of colloid and interface science. 2024 Apr; 659(?):449-462. doi: 10.1016/j.jcis.2023.12.139. [PMID: 38183811]
  • Thaise Boeing, Alana Bittencourt F Lima, Maria Eduarda Busana, Luísa Nathália Bolda Mariano, Luisa Mota da Silva, Rita de Cássia Vilhena da Silva, Priscila de Souza. Characterization of Diclofenac-induced Renal Damage in Normotensive and Hypertensive Rats: A Comparative Analysis. Drug research. 2024 Apr; 74(4):171-179. doi: 10.1055/a-2277-8458. [PMID: 38503307]
  • Xiao-Zhou Hou, Jing Yin, Hai-Yang Wang, Jin-Yu Gu, Tian-Hao Wan, Man-Hong Yang, Di Xia, Qing Zhang. [A multicenter clinical study on the treatment of lateral epicondylitis of humerus by manipulation]. Zhongguo gu shang = China journal of orthopaedics and traumatology. 2024 Mar; 37(3):251-7. doi: 10.12200/j.issn.1003-0034.20230252. [PMID: 38515411]
  • Elackiya Sithamparanathan, Katarzyna Kujawa-Roeleveld, Huub H M Rijnaarts, Nora B Sutton. Hydroponic materials improve organic micropollutant removal in vertical flow constructed wetlands treating wastewater. Chemosphere. 2024 Mar; 352(?):141388. doi: 10.1016/j.chemosphere.2024.141388. [PMID: 38346507]
  • Ioana Boarescu, Paul-Mihai Boarescu, Raluca Maria Pop, Ioana Corina Bocșan, Dan Gheban, Adriana Elena Bulboacă, Anca Dana Buzoianu, Sorana D Bolboacă. Zingiber officinale Root Capsule Extract Synergistically Enhance the Anti-Inflammatory Effects of Diclofenac Sodium in Experimental Acute Inflammation. International journal of molecular sciences. 2024 Feb; 25(3):. doi: 10.3390/ijms25031781. [PMID: 38339059]
  • Kristin H Cochran, Danielle C Westerman, Cassiana C Montagner, Scott Coffin, Lorivic Diaz, Benjamin Fryer, Gary Harraka, Elvis Genbo Xu, Ying Huang, Daniel Schlenk, Dionysios D Dionysiou, Susan D Richardson. Chlorination of Emerging Contaminants for Application in Potable Wastewater Reuse: Disinfection Byproduct Formation, Estrogen Activity, and Cytotoxicity. Environmental science & technology. 2024 Jan; 58(1):704-716. doi: 10.1021/acs.est.3c05978. [PMID: 38109774]
  • Sushmita Negi, Nikunj Tandel, Neeraj K Garg, Prakriti Sharma, Rajinder Kumar, Praveen Sharma, Reetesh Kumar, Sheetal Saini, Aman Sharma, Rajeev K Tyagi. Co-Delivery of Aceclofenac and Methotrexate Nanoparticles Presents an Effective Treatment for Rheumatoid Arthritis. International journal of nanomedicine. 2024; 19(?):2149-2177. doi: 10.2147/ijn.s439359. [PMID: 38482519]
  • Tuyen Van Nguyen, Adam Bořík, Jaylen L Sims, Antonín Kouba, Vladimír Žlábek, Anna Koubová. Toxicological effects of diclofenac on signal crayfish (Pacifastacus leniusculus) as related to weakly acidic and basic water pH. Aquatic toxicology (Amsterdam, Netherlands). 2023 Dec; 265(?):106777. doi: 10.1016/j.aquatox.2023.106777. [PMID: 38035650]
  • Tiantian Chen, Hewei Jiang, Yaoji He, Yawei Shen, Jiajie Fang, Zequn Huang, Yubang Sheng, Xiaowu Chen. Histopathological, physiological, and multi-omics insights into the hepatotoxicity mechanism of nanopolystyrene and/or diclofenac in Mylopharyngodon piceus. Environmental pollution (Barking, Essex : 1987). 2023 Nov; ?(?):122894. doi: 10.1016/j.envpol.2023.122894. [PMID: 37944890]
  • Anjali, Payal Kamboj, Ozair Alam, Harun Patel, Iqrar Ahmad, Syed Sufian Ahmad, Mohd Amir. Design, synthesis, biological evaluation, and in silico studies of quinoxaline derivatives as potent p38α MAPK inhibitors. Archiv der Pharmazie. 2023 Oct; ?(?):e2300301. doi: 10.1002/ardp.202300301. [PMID: 37847883]
  • Amanda Teixeira de Rezende, Ann H Mounteer. Ecological risk assessment of pharmaceuticals and endocrine disrupting compounds in Brazilian surface waters. Environmental pollution (Barking, Essex : 1987). 2023 Sep; 338(?):122628. doi: 10.1016/j.envpol.2023.122628. [PMID: 37783413]
  • Itzayana Pérez-Alvarez, Hariz Islas-Flores, Livier Mireya Sánchez-Aceves, Leobardo Manuel Gómez-Olivan, Germán Chamorro-Cevallos. Spirulina (Arthrospira maxima) mitigates the toxicity induced by a mixture of metal and NSAID in Xenopus laevis. Reproductive toxicology (Elmsford, N.Y.). 2023 09; 120(?):108422. doi: 10.1016/j.reprotox.2023.108422. [PMID: 37330176]
  • Qi Liu, Wenchong Ouyang, Xusheng Yang, Yuanyuan He, Zhengwei Wu, Kostya Ken Ostrikov. Plasma-microbubble treatment and sustainable agriculture application of diclofenac-contaminated wastewater. Chemosphere. 2023 Sep; 334(?):138998. doi: 10.1016/j.chemosphere.2023.138998. [PMID: 37211167]
  • Denis S Baranov, Anna S Kashnik, Anastasiya N Atnyukova, Sergei A Dzuba. Spin-Labeled Diclofenac: Synthesis and Interaction with Lipid Membranes. Molecules (Basel, Switzerland). 2023 Aug; 28(16):. doi: 10.3390/molecules28165991. [PMID: 37630243]
  • Ivan Liakh, Darya Harshkova, Pavel Hrouzek, Kateřina Bišová, Anna Aksmann, Bartosz Wielgomas. Green alga Chlamydomonas reinhardtii can effectively remove diclofenac from the water environment - A new perspective on biotransformation. Journal of hazardous materials. 2023 Aug; 455(?):131570. doi: 10.1016/j.jhazmat.2023.131570. [PMID: 37163898]
  • Iman H Hasan, Amirah Badr, Haneen Almalki, Alanoud Alhindi, Hesham S Mostafa. Podocin, mTOR, and CHOP dysregulation contributes to nephrotoxicity induced of lipopolysaccharide/diclofenac combination in rats: Curcumin and silymarin could afford protective effect. Life sciences. 2023 Aug; 330(?):121996. doi: 10.1016/j.lfs.2023.121996. [PMID: 37536613]
  • Mahak Jain, Pilla Sai Kiran, Partha Sarathi Ghosal, Ashok Kumar Gupta. Development of microbial fuel cell integrated constructed wetland (CMFC) for removal of paracetamol and diclofenac in hospital wastewater. Journal of environmental management. 2023 Aug; 344(?):118686. doi: 10.1016/j.jenvman.2023.118686. [PMID: 37536238]
  • Simone S Silva, Luísa C Rodrigues, Emanuel M Fernandes, Diana Soares da Costa, Denise G Villalva, Watson Loh, Rui L Reis. Chitosan/Virgin-Coconut-Oil-Based System Enriched with Cubosomes: A 3D Drug-Delivery Approach. Marine drugs. 2023 Jul; 21(7):. doi: 10.3390/md21070394. [PMID: 37504925]
  • Nathalie Marte Ureña, Catiúscia Padilha de Oliveira, Silvia Stanisçuaski Guterres, Adriana Raffin Pohlmann, Oscar Tadeu Ferreira da Costa, Antonio Luiz Boechat. The Anti-Arthritic Activity of Diclofenac Lipid-Core Nanocapsules: Stereological Analysis Showing More Protection of Deep Joint Components. Molecules (Basel, Switzerland). 2023 Jul; 28(13):. doi: 10.3390/molecules28135219. [PMID: 37446881]
  • João Vitor Raupp de Oliveira, Pedro Leardin Silveira, Gabriela Spingolon, Gabriel Antonio Lopes Alves, Flávia Pires Peña, Tanira Alessandra Silveira Aguirre. Polymeric nanoparticles containing babassu oil: A proposed drug delivery system for controlled release of hydrophilic compounds. Chemistry and physics of lipids. 2023 07; 253(?):105304. doi: 10.1016/j.chemphyslip.2023.105304. [PMID: 37080377]
  • Sara S Marques, David J H Cant, Caterina Minelli, Marcela A Segundo. Combining orthogonal measurements to unveil diclofenac encapsulation into polymeric and lipid nanocarriers. Analytica chimica acta. 2023 Jun; 1262(?):341234. doi: 10.1016/j.aca.2023.341234. [PMID: 37179055]
  • Benish Rauf, Sobia Alyasi, Naureen Zahra, Sohail Ahmad, Abid Sarwar, Tariq Aziz, Metab Alharbi, Abdulrahman Alshammari, Abdullah F Alasmari. Evaluating the influence of Aloe barbadensis extracts on edema induced changes in C-reactive protein and interleukin-6 in albino rats through in vivo and in silico approaches. Acta biochimica Polonica. 2023 Jun; 70(2):425-433. doi: 10.18388/abp.2020_6705. [PMID: 37329564]
  • Taylan Dolu, Bilgehan Nas. Dissemination of nonsteroidal anti-inflammatory drugs (NSAIDs) and metabolites from wastewater treatment plant to soils and agricultural crops via real-scale different agronomic practices. Environmental research. 2023 06; 227(?):115731. doi: 10.1016/j.envres.2023.115731. [PMID: 36958380]
  • Dimitrina Zheleva-Dimitrova, Rumyana Simeonova, Magdalena Kondeva-Burdina, Yonko Savov, Vessela Balabanova, Gokhan Zengin, Alexandra Petrova, Reneta Gevrenova. Antioxidant and Hepatoprotective Potential of Echinops ritro L. Extracts on Induced Oxidative Stress In Vitro/In Vivo. International journal of molecular sciences. 2023 Jun; 24(12):. doi: 10.3390/ijms24129999. [PMID: 37373147]
  • Radhika Khanna, H R Chitme, Khushaboo Bhadoriya, Y C Tripathi, V K Varshney. In vitro and in vivo anti-inflammatory activity of Cupressus torulosa D.DON needles extract and its chemical characterization. Journal of ethnopharmacology. 2023 May; 314(?):116578. doi: 10.1016/j.jep.2023.116578. [PMID: 37172917]
  • Durbek Usmanov, Aziz Azamatov, Temur Baykuziyev, Ugiloy Yusupova, Bakhtiyor Rasulev. Chemical constituents, anti-inflammatory and analgesic activities of iridoids preparation from Phlomoides labiosa bunge. Natural product research. 2023 May; 37(10):1709-1713. doi: 10.1080/14786419.2022.2104274. [PMID: 35879860]
  • Kamran Jalil, Shabir Ahmad, Nazrul Islam, Rahim Ullah, Qudsia Jalil, Sulaiman Sulaiman, Anoosha Sajjad, Riaz Ullah, Ali S Alqahtani, Ahmed Bari, Hidayat Hussain, Essam A Ali. One Pot Synthesis, Biological Efficacy of AuNPs and Au-Amoxicillin Conjugates Functionalized with Crude Flavonoids Extract of Micromeria biflora. Molecules (Basel, Switzerland). 2023 Apr; 28(8):. doi: 10.3390/molecules28083320. [PMID: 37110554]
  • Fabian Balk, Juliane Hollender, Kristin Schirmer. Investigating the bioaccumulation potential of anionic organic compounds using a permanent rainbow trout liver cell line. Environment international. 2023 04; 174(?):107798. doi: 10.1016/j.envint.2023.107798. [PMID: 36965398]
  • Jyoti Sharma, Iqra Mariam, Mukul Suresh Kareya, Pannaga Pavan Jutur, Monika Joshi, Harish, Amit Bhatnagar, Akhilesh K Chaurasia, Subhasha Nigam. Metabolomic response of microalgae towards diclofenac sodium during its removal from water and concomitant recovery of pigments and lipids. Bioresource technology. 2023 Mar; 371(?):128617. doi: 10.1016/j.biortech.2023.128617. [PMID: 36640815]
  • Sujatha M Hanumegowda, Chandramma Srinivasa, Ashwini Shivaiah, Manjula M Venkatappa, Sebestian Santhosh, Rajesh R, Sathisha J Gonchigar, Devaraja Sannaningaiah. Antioxidant and Antithrombotic Activities of Kenaf Seed (Hibiscus cannabinus) Coat Ethanol Extract in Sprague Dawley Rats. Applied biochemistry and biotechnology. 2023 Feb; 195(2):772-800. doi: 10.1007/s12010-022-04144-8. [PMID: 36173546]
  • Márton Pápai, Tibor Benedek, András Táncsics, Till L V Bornemann, Julia Plewka, Alexander J Probst, Daood Hussein, Gergely Maróti, Ofir Menashe, Balázs Kriszt. Selective enrichment, identification, and isolation of diclofenac, ibuprofen, and carbamazepine degrading bacteria from a groundwater biofilm. Environmental science and pollution research international. 2023 Jan; ?(?):. doi: 10.1007/s11356-022-24975-6. [PMID: 36690856]
  • Saravanakumar Selvaraj, Jung-Hwa Oh, Seokjoo Yoon, Jürgen Borlak. Diclofenac Disrupts the Circadian Clock and through Complex Cross-Talks Aggravates Immune-Mediated Liver Injury-A Repeated Dose Study in Minipigs for 28 Days. International journal of molecular sciences. 2023 01; 24(2):. doi: 10.3390/ijms24021445. [PMID: 36674967]
  • Khalil Said, Muhammad Hamayun, Mamoona Rauf, Sumera Afzal Khan, Muhammad Arif, Abdulwahed Fahad Alrefaei, Mikhlid H Almutairi, Sajid Ali. Simultaneous Study of Analysis of Anti-inflammatory Potential of Dryopteris ramosa (C. Hope) C. Chr. using GC-Mass and Computational Modeling on the Xylene-induced Ear Oedema in Mouse Model. Current pharmaceutical design. 2023; 29(41):3324-3339. doi: 10.2174/0113816128290636231129074039. [PMID: 38111115]
  • Sanjeeb Mohapatra, Daniel Snow, Patrick Shea, Andy Gálvez-Rodríguez, Manish Kumar, Lokesh P Padhye, Suparna Mukherji. Photodegradation of a mixture of five pharmaceuticals commonly found in wastewater: Experimental and computational analysis. Environmental research. 2023 01; 216(Pt 3):114659. doi: 10.1016/j.envres.2022.114659. [PMID: 36328221]
  • Sana Zahoor, Sadia Sheraz, Dilawar Farhan Shams, Gauhar Rehman, Saira Nayab, Muhammad Ishaq Ali Shah, Muhammad Ateeq, Said Karim Shah, Tanveer Ahmad, Sulaiman Shams, Waliullah Khan. Biosynthesis and Anti-inflammatory Activity of Zinc Oxide Nanoparticles Using Leaf Extract of Senecio chrysanthemoides. BioMed research international. 2023; 2023(?):3280708. doi: 10.1155/2023/3280708. [PMID: 37082193]
  • L Ponce-Robles, L Benelhadj, A J García-García, F Pedrero-Salcedo, P A Nortes-Tortosa, J Albacete, J J Alarcón. Risk assessment for uptake and accumulation of pharmaceuticals by baby leaf lettuce irrigated with reclaimed water under commercial agricultural activities. Journal of environmental management. 2022 Dec; 324(?):116321. doi: 10.1016/j.jenvman.2022.116321. [PMID: 36179471]
  • Mai M Anwar, Ibrahim M Ibrahim Laila. Mitigative effect of caffeine against diclofenac-induced hepato-renal damage and chromosomal aberrations in male albino rats. BMC complementary medicine and therapies. 2022 Dec; 22(1):327. doi: 10.1186/s12906-022-03802-y. [PMID: 36482339]
  • Bin Wu, Duo Xu, Hao Wang, Runyu Xu, Naibing Qin, Jinlong Han. Wetland plant-derived biochar enhances the diclofenac treatment performance in vertical subsurface flow constructed wetlands. Environmental research. 2022 12; 215(Pt 1):114326. doi: 10.1016/j.envres.2022.114326. [PMID: 36113575]
  • Mariana N Miranda, Ana R Lado Ribeiro, Adrián M T Silva, M Fernando R Pereira. Can aged microplastics be transport vectors for organic micropollutants? - Sorption and phytotoxicity tests. The Science of the total environment. 2022 Dec; 850(?):158073. doi: 10.1016/j.scitotenv.2022.158073. [PMID: 35981591]
  • Han Bi Ji, Jae Young Hong, Cho Rim Kim, Chang Hee Min, Jae Hoon Han, Min Ji Kim, Se-Na Kim, Cheol Lee, Young Bin Choy. Microchannel-embedded implantable device with fibrosis suppression for prolonged controlled drug delivery. Drug delivery. 2022 Dec; 29(1):489-498. doi: 10.1080/10717544.2022.2032873. [PMID: 35147052]
  • Aneta Kalvodová, Jarmila Zbytovská. Lipid nanocapsules enhance the transdermal delivery of drugs regardless of their physico-chemical properties. International journal of pharmaceutics. 2022 Nov; 628(?):122264. doi: 10.1016/j.ijpharm.2022.122264. [PMID: 36209979]
  • Chun Shu, Fang Yang, Fubing Zhu, Dongping Hua. Effect of external use of Qingluo San on clinical efficacy in patients with acute gouty arthritis. European journal of medical research. 2022 Nov; 27(1):245. doi: 10.1186/s40001-022-00872-z. [PMID: 36369177]
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