1-Methyluric acid (BioDeep_00000405547)

Main id: BioDeep_00000001202

 

natural product


代谢物信息卡片


1-Methyluric acid

化学式: C6H6N4O3 (182.044)
中文名称: 1-甲基尿酸
谱图信息: 最多检出来源 Mus musculus(urine) 44.2%

分子结构信息

SMILES: CN1C(=O)C2=C(NC(=O)N2)NC1=O
InChI: InChI=1S/C6H6N4O3/c1-10-4(11)2-3(9-6(10)13)8-5(12)7-2/h1H3,(H,9,13)(H2,7,8,12)

描述信息

An oxopurine that is 7,9-dihydro-1H-purine-2,6,8(3H)-trione substituted by a methyl group at N-1. It is one of the metabolites of caffeine found in human urine.

同义名列表

2 个代谢物同义名

1-Methyluric acid; 1-Methyluric acid



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 AHR, APOE, CYP1A1, CYP2A6, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP3A4, NAT2, NR3C1, XDH
Peripheral membrane protein 2 CYP1A1, CYP2E1
Endoplasmic reticulum membrane 9 CYP1A1, CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A5
Nucleus 5 AHR, APOE, NAT2, NR3C1, PPARA
cytosol 5 AHR, GPT, NAT2, NR3C1, XDH
dendrite 1 APOE
centrosome 1 NR3C1
nucleoplasm 3 AHR, NR3C1, PPARA
Cell membrane 1 NAT2
Multi-pass membrane protein 2 ATP4A, NAT2
Synapse 1 NR3C1
glutamatergic synapse 1 APOE
Golgi apparatus 1 APOE
Golgi membrane 1 INS
mitochondrial inner membrane 2 CYP1A1, CYP2E1
neuronal cell body 2 APOE, NAT2
plasma membrane 5 APOE, ATP4A, CYP2C8, CYP2C9, NAT2
Membrane 9 APOE, ATP4A, CYP2A6, CYP2D6, CYP3A4, CYP3A5, NAT2, NR3C1, VEGFB
apical plasma membrane 1 ATP4A
axon 1 NAT2
basolateral plasma membrane 1 NAT2
extracellular exosome 3 APOE, GPT, NAT2
endoplasmic reticulum 2 APOE, CYP2D6
extracellular space 6 APOE, ATP4A, IL6, INS, VEGFB, XDH
mitochondrion 3 CYP1A1, CYP2D6, NR3C1
protein-containing complex 2 AHR, NR3C1
intracellular membrane-bounded organelle 9 CYP1A1, CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A5
Microsome membrane 7 CYP1A1, CYP1A2, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A5
Secreted 4 APOE, IL6, INS, VEGFB
extracellular region 4 APOE, IL6, INS, VEGFB
Single-pass membrane protein 1 CYP2D6
mitochondrial matrix 1 NR3C1
transcription regulator complex 2 AHR, NAT2
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 NR3C1
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 1 APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 1 APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 1 APOE
Early endosome 1 APOE
Apical cell membrane 1 ATP4A
Mitochondrion inner membrane 2 CYP1A1, CYP2E1
Cytoplasm, cytoskeleton, spindle 1 NR3C1
spindle 1 NR3C1
extracellular matrix 1 APOE
Peroxisome 1 XDH
sarcoplasmic reticulum 1 XDH
collagen-containing extracellular matrix 1 APOE
nuclear speck 1 NR3C1
chromatin 3 AHR, NR3C1, PPARA
Chromosome 1 NR3C1
Secreted, extracellular space 1 APOE
blood microparticle 1 APOE
endosome lumen 1 INS
aryl hydrocarbon receptor complex 1 AHR
Nucleus, nucleoplasm 1 NR3C1
Melanosome 1 APOE
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 APOE, IL6, INS
platelet alpha granule lumen 1 VEGFB
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 APOE
cytoplasmic microtubule 1 CYP2A6
synaptic cleft 1 APOE
external side of apical plasma membrane 1 NAT2
[Isoform Alpha]: Cytoplasm 1 NR3C1
discoidal high-density lipoprotein particle 1 APOE
endocytic vesicle lumen 1 APOE
chylomicron remnant 1 APOE
intermediate-density lipoprotein particle 1 APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
[Isoform Beta]: Nucleus 1 NR3C1
[Isoform Alpha-B]: Nucleus 1 NR3C1
interleukin-6 receptor complex 1 IL6
potassium:proton exchanging ATPase complex 1 ATP4A
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
NatA complex 1 NAT2


文献列表

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