5,7,3'-Trihydroxy-4'-methoxyflavanone (BioDeep_00000017486)
Main id: BioDeep_00000398535
human metabolite PANOMIX_OTCML-2023 Endogenous BioNovoGene_Lab2019
代谢物信息卡片
化学式: C16H14O6 (302.079)
中文名称: 橙皮素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)O
InChI: InChI=1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3
描述信息
5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one is an ether and a member of flavonoids.
5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one is a natural product found in Allium caeruleum, Allium caesium, and other organisms with data available.
The S-form is It is isolated from Brickellia vernicosa, Persica vulgaris (preferred genus name Prunus), Citrus and Mentha species [CCD
(Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation.
(Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation.
Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis.
Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis.
同义名列表
26 个代谢物同义名
(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3,5,7-Trihydroxy-4-methoxyflavanone; 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)-; 4H-1-Benzopyran-4-one,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)-; 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one; 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one; 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one; 5,7-dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)chroman-4-one; 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one; 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone; (+/-)-Hesperetin, analytical standard; 5,7,3-Trihydroxy-4-methoxyflavanone; Flavanone,5,7-trihydroxy-4-methoxy-; 3,7-Trihydroxy-4-methoxyflavanone; 5,3-Trihydroxy-4-methoxyflavanone; Hesperetin, analytical standard; Hesperetin, >=95\\%; (Rac)-Hesperetin; (+/-)-Hesperetin; rac-Hesperetin; (R)-Hesperetin; ACon1_002327; NCI60_014043; hesperetine; Hesperetin; Hesperetin
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:95167
- PubChem: 3593
- HMDB: HMDB0030746
- ChEMBL: CHEMBL88169
- foodb: FDB002676
- chemspider: 3467
- CAS: 69097-99-0
- CAS: 520-33-2
- medchemexpress: HY-N0168A
- medchemexpress: HY-N0168
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-703
- KEGG: C01709
- PubChem: 4847
- KNApSAcK: 28230
- LOTUS: LTS0070100
- wikidata: Q27166968
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
14 个相关的物种来源信息
- 138318 - Allium caeruleum: 10.1051/ANPHYS/197702020005
- 166796 - Allium caesium: 10.1051/ANPHYS/197702020005
- 558547 - Citrus deliciosa:
- 37334 - Citrus maxima:
- 171251 - Citrus medica:
- 85571 - Citrus reticulata:
- 2711 - Citrus sinensis Osbeck: -
- 37690 - Citrus trifoliata:
- 55188 - Citrus unshiu:
- 475932 - Citrus wilsonii:
- 9606 - Homo sapiens: -
- 33090 - Plants: -
- 2849020 - Schizonepeta tenuifolia Briq.: -
- 569774 - 金线莲: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- You-Lan Yang, Hsin-Te Hsu, Kuo-Hsien Wang, Cheng-Ying Han, Chien-Ming Chen, Chi-Ming Chen, Wun-Chang Ko. Hesperetin-7,3'-O-dimethylether selectively inhibits phosphodiesterase 4 and effectively suppresses ovalbumin-induced airway hyperresponsiveness with a high therapeutic ratio.
Journal of biomedical science.
2011 Nov; 18(?):84. doi:
10.1186/1423-0127-18-84. [PMID: 22074248] - Fatemeh Haidari, Seid Ali Keshavarz, Mohammad Reza Rashidi, Majid Mohammad Shahi. Orange juice and hesperetin supplementation to hyperuricemic rats alter oxidative stress markers and xanthine oxidoreductase activity.
Journal of clinical biochemistry and nutrition.
2009 Nov; 45(3):285-91. doi:
10.3164/jcbn.09-15. [PMID: 19902018] - Meng-Xia Xie, Xiao-Yun Xu, Ying-Dian Wang. Interaction between hesperetin and human serum albumin revealed by spectroscopic methods.
Biochimica et biophysica acta.
2005 Jun; 1724(1-2):215-24. doi:
10.1016/j.bbagen.2005.04.009. [PMID: 15923087]
