2-Oxazolidinone (BioDeep_00000006286)
Secondary id: BioDeep_00001868392
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
1,3 Oxazolidine 2 one
化学式: C3H5NO2 (87.032027)
中文名称: 2-噁唑烷酮, 2-恶唑烷酮
谱图信息:
最多检出来源 Homo sapiens(blood) 80.39%
分子结构信息
SMILES: C1COC(=O)N1
InChI: InChI=1S/C3H5NO2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
描述信息
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D000890 - Anti-Infective Agents > D023303 - Oxazolidinones
同义名列表
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:1237
- KEGG: C93484
- KEGG: C06695
- PubChem: 73949
- HMDB: HMDB0245282
- Metlin: METLIN66496
- ChEMBL: CHEMBL1867161
- Wikipedia: 2-Oxazolidone
- MeSH: Oxazolidinones
- chemspider: 66579
- CAS: 51667-26-6
- CAS: 497-25-6
- PMhub: MS000019308
- PubChem: 8920
- 3DMET: B02093
- NIKKAJI: J36.850D
- KNApSAcK: 1237
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Masahiro Toyokawa, Noboru Ohana, Daiki Tanno, Minako Imai, Yukiko Takano, Kazutaka Ohashi, Tomonari Yamashita, Kyoichi Saito, Hiroki Takahashi, Hiroki Shimura. In vitro activity of tedizolid against 43 species of Nocardia species.
Scientific reports.
2024 03; 14(1):5342. doi:
10.1038/s41598-024-55916-7. [PMID: 38438563] - Kristina Klobucar, Emily Jardine, Maya A Farha, Marc R MacKinnon, Meghan Fragis, Brenda Nkonge, Timsy Bhando, Louis Borrillo, Caressa N Tsai, Jarrod W Johnson, Brian K Coombes, Jakob Magolan, Eric D Brown. Genetic and Chemical Screening Reveals Targets and Compounds to Potentiate Gram-Positive Antibiotics against Gram-Negative Bacteria.
ACS infectious diseases.
2022 10; 8(10):2187-2197. doi:
10.1021/acsinfecdis.2c00357. [PMID: 36098580] - Jinqian Yu, Kai Wang, Hengqiang Zhao, Long Chen, Xiao Wang. Bioactive constituents from the leaves of Lonicera japonica.
Fitoterapia.
2022 Oct; 162(?):105277. doi:
10.1016/j.fitote.2022.105277. [PMID: 35970409] - Mingming Li, Yang Xiao, Lianggui Xiao, Yu Li, Mengting Jia, Yu Sun, Tingli Pan, Lei Zhou, Yixing Li. Epigoitrin alleviates lipid and glucose metabolic disorders induced by a high-fat diet.
Food & function.
2022 Jul; 13(13):7260-7273. doi:
10.1039/d2fo00242f. [PMID: 35723416] - Carlos Rodríguez-Lucas, Javier Fernández, Xenia Vázquez, María de Toro, Víctor Ladero, Carlos Fuster, Rosaura Rodicio, María Rosario Rodicio. Detection of the optrA Gene Among Polyclonal Linezolid-Susceptible Isolates of Enterococcus faecalis Recovered from Community Patients.
Microbial drug resistance (Larchmont, N.Y.).
2022 Jul; 28(7):773-779. doi:
10.1089/mdr.2021.0402. [PMID: 35727074] - Anselm Jorda, Beatrix Wulkersdorfer, Christian Schörgenhofer, Peter Matzneller, Valentin Al Jalali, Martin Bauer, Michael Wölf-Duchek, Edith Lackner, Christoph Dorn, Bernd Jilma, Markus Zeitlinger. Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial.
The Journal of antimicrobial chemotherapy.
2022 04; 77(5):1424-1431. doi:
10.1093/jac/dkac039. [PMID: 35165727] - Paul Bruinenberg, Jerry Nedelman, Tian J Yang, Fran Pappas, Dan Everitt. Single Ascending-Dose Study To Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid in Healthy Adult Subjects.
Antimicrobial agents and chemotherapy.
2022 04; 66(4):e0210821. doi:
10.1128/aac.02108-21. [PMID: 35285241] - E Sammons, J C Hopewell, F Chen, W Stevens, K Wallendszus, E Valdes-Marquez, R Dayanandan, C Knott, K Murphy, E Wincott, A Baxter, R Goodenough, M Lay, M Hill, S Macdonnell, G Fabbri, D Lucci, M Fajardo-Moser, S Brenner, D Hao, H Zhang, J Liu, B Wuhan, S Mosegaard, W Herrington, C Wanner, C Angermann, G Ertl, A Maggioni, P Barter, B Mihaylova, Y Mitchel, R Blaustein, S Goto, J Tobert, P DeLucca, Y Chen, Z Chen, A Gray, R Haynes, J Armitage, C Baigent, S Wiviott, C Cannon, E Braunwald, R Collins, L Bowman, M Landray. Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease.
European heart journal.
2022 04; 43(14):1416-1424. doi:
10.1093/eurheartj/ehab863. [PMID: 34910136] - Alexandra Lehman, Barbara A Santevecchi, Kelly L Maguigan, Nicholas Laconi, Tyler J Loftus, Alicia M Mohr, Bethany R Shoulders. Impact of Empiric Linezolid for Necrotizing Soft Tissue Infections on Duration of Methicillin-Resistant Staphylococcus aureus-Active Therapy.
Surgical infections.
2022 Apr; 23(3):313-317. doi:
10.1089/sur.2021.329. [PMID: 35133888] - Ru Zhao, Xinyu Yang, Aoqi Zhang, Tieyang Zhou, Yunwei Zhou, Lei Yang. An efficient approach for simultaneously obtaining oil and epigoitrin from Orychophragmus violaceus seeds by microwave-mediated immiscible binary solvent extraction.
Food chemistry.
2022 Mar; 372(?):131258. doi:
10.1016/j.foodchem.2021.131258. [PMID: 34627086] - Yu Wang, Hailan Wu, Junzhen Wu, Yaxin Fan, Xiaofen Liu, Yi Li, Jiali Hu, Jing Zhang, Beining Guo. Development and validation of ultra-performance liquid chromatography-tandem mass spectrometric methods for simultaneous and rapid determination of contezolid and its major metabolite M2 in plasma and urine samples and its application to a study in subjects with moderate liver impairment.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2022 Feb; 1191(?):123129. doi:
10.1016/j.jchromb.2022.123129. [PMID: 35066246] - Naser F Al-Tannak, Oludotun A Phillips, Husein J Kamal, Ahmed Hemdan. Development and Validation of Stability-Indicating Assay Method for a Novel Oxazolidinone (PH-192) with Anticonvulsant Activity by Using UHPLC-QToF-MS.
Molecules (Basel, Switzerland).
2022 Feb; 27(3):. doi:
10.3390/molecules27031090. [PMID: 35164353] - Sunena Jha, Dinanath Mishra. Evaluation of Brain Targeting Potential of Zolmitriptan Mucoadhesive Nanoparticles for Intranasal Drug Delivery.
Pharmaceutical nanotechnology.
2022; 10(2):113-124. doi:
10.2174/2211738510666220303160414. [PMID: 35240970] - Yuki Sato, Yoh Takekuma, Takayuki Daisho, Hitoshi Kashiwagi, Shungo Imai, Mitsuru Sugawara. Development of a Method of Liquid Chromatography Coupled with Tandem Mass Spectrometry for Simultaneous Determination of Linezolid and Tedizolid in Human Plasma.
Biological & pharmaceutical bulletin.
2022; 45(4):421-428. doi:
10.1248/bpb.b21-00798. [PMID: 35370266] - Yasuhiro Tsuji, Miki Numajiri, Chika Ogami, Fumihiro Kurosaki, Aoi Miyamoto, Takahiko Aoyama, Hitoshi Kawasuji, Kentaro Nagaoka, Yoshiaki Matsumoto, Hideto To, Yoshihiro Yamamoto. Development of a simple method for measuring tedizolid concentration in human serum using HPLC with a fluorescent detector.
Medicine.
2021 Dec; 100(49):e28127. doi:
10.1097/md.0000000000028127. [PMID: 34889275] - Lingling Han, Yudi Jia, Yanjia Zhao, Chen Sun, Min Zhao, Ying Peng, Jiang Zheng. Metabolic activation of zolmitriptan mediated by CYP2D6.
Xenobiotica; the fate of foreign compounds in biological systems.
2021 Nov; 51(11):1292-1302. doi:
10.1080/00498254.2021.1938290. [PMID: 34096834] - Xiaojie Wu, Jian Meng, Hong Yuan, Dafang Zhong, Jicheng Yu, Guoying Cao, Xingdang Liu, Beining Guo, Yuancheng Chen, Yi Li, Yaoguo Shi, Mikhail F Gordeev, Jufang Wu, Jing Zhang. Pharmacokinetics and Disposition of Contezolid in Humans: Resolution of a Disproportionate Human Metabolite for Clinical Development.
Antimicrobial agents and chemotherapy.
2021 10; 65(11):e0040921. doi:
10.1128/aac.00409-21. [PMID: 34398672] - Amand F Schmidt, Nicholas B Hunt, Maria Gordillo-Marañón, Pimphen Charoen, Fotios Drenos, Mika Kivimaki, Deborah A Lawlor, Claudia Giambartolomei, Olia Papacosta, Nishi Chaturvedi, Joshua C Bis, Christopher J O'Donnell, Goya Wannamethee, Andrew Wong, Jackie F Price, Alun D Hughes, Tom R Gaunt, Nora Franceschini, Dennis O Mook-Kanamori, Magdalena Zwierzyna, Reecha Sofat, Aroon D Hingorani, Chris Finan. Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.
Nature communications.
2021 09; 12(1):5640. doi:
10.1038/s41467-021-25703-3. [PMID: 34561430] - Petr Vachal, Joseph L Duffy, Louis-Charles Campeau, Rupesh P Amin, Kaushik Mitra, Beth Ann Murphy, Pengcheng P Shao, Peter J Sinclair, Feng Ye, Revathi Katipally, Zhijian Lu, Debra Ondeyka, Yi-Heng Chen, Kake Zhao, Wanying Sun, Sriram Tyagarajan, Jianming Bao, Sheng-Ping Wang, Josee Cote, Concetta Lipardi, Daniel Metzger, Dennis Leung, Georgy Hartmann, Gordon K Wollenberg, Jian Liu, Lushi Tan, Yingju Xu, Qinghao Chen, Guiquan Liu, Robert O Blaustein, Douglas G Johns. Invention of MK-8262, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor Backup to Anacetrapib with Best-in-Class Properties.
Journal of medicinal chemistry.
2021 09; 64(18):13215-13258. doi:
10.1021/acs.jmedchem.1c00959. [PMID: 34375108] - Ying-Chun Chien, Yu-Lin Lee, Po-Yu Liu, Min-Chi Lu, Pei-Lan Shao, Po-Liang Lu, Shu-Hsing Cheng, Chi-Ying Lin, Ting-Shu Wu, Muh-Yong Yen, Lih-Shinn Wang, Chang-Pan Liu, Wen-Sen Lee, Zhi-Yuan Shi, Yao-Shen Chen, Fu-Der Wang, Shu-Hui Tseng, Yu-Hui Chen, Wang-Huei Sheng, Chun-Ming Lee, Yen-Hsu Chen, Wen-Chien Ko, Po-Ren Hsueh. National surveillance of antimicrobial susceptibilities to dalbavancin, telavancin, tedizolid, eravacycline, omadacycline and other comparator antibiotics and serotype distribution of invasive Streptococcus pneumoniae isolates in adults: results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) programme in 2017-2020.
Journal of global antimicrobial resistance.
2021 09; 26(?):308-316. doi:
10.1016/j.jgar.2021.07.005. [PMID: 34289409] - Pakinaz Y Khashaba, Azza H Rageh, Noha N Atia, Sally A El Zohny. Vortex-assisted dispersive solid phase microextraction using Fe3O4/FeOOH magnetic nanocomposites for high-performance thin-layer chromatographic determination of zolmitriptan in rabbit plasma samples.
Journal of chromatography. A.
2021 Aug; 1651(?):462276. doi:
10.1016/j.chroma.2021.462276. [PMID: 34107401] - Sonia Nina Coccitto, Simona Fioriti, Marzia Cinthi, Gianluca Morroni, Elisabetta Di Giannatale, Marina Mingoia, Andrea Brenciani, Eleonora Giovanetti. Detection of phenicol-oxazolidinone resistance gene optrA in Aerococcus viridans from bovine faeces, Italy.
The Journal of antimicrobial chemotherapy.
2021 08; 76(9):2479-2481. doi:
10.1093/jac/dkab162. [PMID: 34008028] - Hanjing Chen, Weili Chen, Hui Li, Hongrong Xu, Fei Yuan, Lei Sheng, Chao Liu, Pingping Lin, Mengjie Yang, Xuening Li, Yang Liu, Brittany Marie Walker, Ferdous Gheyas, Marian Iwamoto, S Aubrey Stoch, Rajesh Krishna. Pharmacokinetics, Safety and Tolerability of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein (CETP) Inhibitor, After Single and Multiple Doses in Healthy Chinese Subjects.
Advances in therapy.
2021 07; 38(7):3973-3985. doi:
10.1007/s12325-021-01794-8. [PMID: 34101144] - Lili Rong, Xiaohu Wu, Jun Xu, Fengshou Dong, Xingang Liu, Hanqing Xu, Junli Cao, Yongquan Zheng. Clomazone improves the interactions between soil microbes and affects C and N cycling functions.
The Science of the total environment.
2021 May; 770(?):144730. doi:
10.1016/j.scitotenv.2020.144730. [PMID: 33736380] - Marija Stevanović, Dragica Brkić, Tanja Tomić, Varja Mihajlović, Tijana Đorđević, Slavica Gašić. Effects of the technical ingredient clomazone and its two formulated products on aquatic macrophytes.
Environmental pollution (Barking, Essex : 1987).
2021 May; 277(?):116753. doi:
10.1016/j.envpol.2021.116753. [PMID: 33640824] - Feng Guo, Masaki Endo, Takuya Yamaguchi, Akira Uchino, Yukari Sunohara, Hiroshi Matsumoto, Satoshi Iwakami. Investigation of clomazone-tolerance mechanism in a long-grain cultivar of rice.
Pest management science.
2021 May; 77(5):2454-2461. doi:
10.1002/ps.6274. [PMID: 33432689] - Makoto Kai, Ryota Tanaka, Yosuke Suzuki, Koji Goto, Yoshifumi Ohchi, Norihisa Yasuda, Ryosuke Tatsuta, Takaaki Kitano, Hiroki Itoh. Simultaneous quantification of plasma levels of 12 antimicrobial agents including carbapenem, anti-methicillin-resistant Staphylococcus aureus agent, quinolone and azole used in intensive care unit using UHPLC-MS/MS method.
Clinical biochemistry.
2021 Apr; 90(?):40-49. doi:
10.1016/j.clinbiochem.2021.01.012. [PMID: 33539809] - Richard Court, Chad M Centner, Maxwell Chirehwa, Lubbe Wiesner, Paolo Denti, Nihal de Vries, Joseph Harding, Tawanda Gumbo, Gary Maartens, Helen McIlleron. Neuropsychiatric toxicity and cycloserine concentrations during treatment for multidrug-resistant tuberculosis.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2021 Apr; 105(?):688-694. doi:
10.1016/j.ijid.2021.03.001. [PMID: 33684562] - Yongqi Wu, Bin Wang, Haijia Lu, Hongyi Zhao, Beibei Yang, Li Li, Yu Lu, Dongfeng Zhang, Ning Sun, Haihong Huang. Identification of Novel Tricyclic Benzo[1,3]oxazinyloxazolidinones as Potent Antibacterial Agents with Excellent Pharmacokinetic Profiles against Drug-Resistant Pathogens.
Journal of medicinal chemistry.
2021 03; 64(6):3234-3248. doi:
10.1021/acs.jmedchem.0c02153. [PMID: 33705128] - Mark Trinder, Yanan Wang, Christian M Madsen, Tatjana Ponomarev, Lubos Bohunek, Brendan A Daisely, HyeJin Julia Kong, Lisanne L Blauw, Børge G Nordestgaard, Anne Tybjærg-Hansen, Mark M Wurfel, James A Russell, Keith R Walley, Patrick C N Rensen, John H Boyd, Liam R Brunham. Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis.
Circulation.
2021 03; 143(9):921-934. doi:
10.1161/circulationaha.120.048568. [PMID: 33228395] - Ryota Tanaka, Makoto Kai, Koji Goto, Yoshifumi Ohchi, Norihisa Yasuda, Ryosuke Tatsuta, Takaaki Kitano, Hiroki Itoh. High-throughput and wide-range simultaneous determination of linezolid, daptomycin and tedizolid in human plasma using ultra-performance liquid chromatography coupled to tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2021 Feb; 194(?):113764. doi:
10.1016/j.jpba.2020.113764. [PMID: 33298382] - Marie C Hupe, Maximilian Büttner, Pouriya Faraj Tabrizi, Axel S Merseburger, Markus A Kuczyk, Florian Imkamp. Hemopatch® as a Hemostatic Agent is Safe in Partial Nephrectomy: A Large, Single-Surgeon Retrospective Evaluation.
Advances in therapy.
2021 02; 38(2):1024-1034. doi:
10.1007/s12325-020-01584-8. [PMID: 33277680] - Mark P Metzinger, Suzanne Saldanha, Jaskeerat Gulati, Kershaw V Patel, Ayea El-Ghazali, Sneha Deodhar, Parag H Joshi, Colby Ayers, Anand Rohatgi. Effect of Anacetrapib on Cholesterol Efflux Capacity: A Substudy of the DEFINE Trial.
Journal of the American Heart Association.
2020 12; 9(24):e018136. doi:
10.1161/jaha.120.018136. [PMID: 33263263] - Maxwell T Chirehwa, Richard Court, Mariana de Kock, Lubbe Wiesner, Nihal de Vries, Joseph Harding, Tawanda Gumbo, Gary Maartens, Rob Warren, Paolo Denti, Helen McIlleron. Population Pharmacokinetics of Cycloserine and Pharmacokinetic/Pharmacodynamic Target Attainment in Multidrug-Resistant Tuberculosis Patients Dosed with Terizidone.
Antimicrobial agents and chemotherapy.
2020 10; 64(11):. doi:
10.1128/aac.01381-20. [PMID: 32816738] - Lisha Li, Jun Zhu, Feijun Ye, Zhongliang Duan, Jin Zhou, Zengshu Huang, Ling Wang. Upregulation of the lncRNA SRLR in polycystic ovary syndrome regulates cell apoptosis and IL-6 expression.
Cell biochemistry and function.
2020 Oct; 38(7):880-885. doi:
10.1002/cbf.3507. [PMID: 31999854] - Kaoru Kobayashi, Yoshikazu Abe, Asuka Kawai, Takao Furihata, Takuro Endo, Hiroo Takeda. Pharmacokinetic Drug Interactions of an Orally Available TRH Analog (Rovatirelin) With a CYP3A4/5 and P-Glycoprotein Inhibitor (Itraconazole).
Journal of clinical pharmacology.
2020 10; 60(10):1314-1323. doi:
10.1002/jcph.1628. [PMID: 32459872] - Jung Sun Lee, Ji Seon Oh, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong. Rapid reduction in uric acid by a urate-lowering agent is associated with recurrent cardiovascular events.
Medical hypotheses.
2020 Aug; 141(?):109740. doi:
10.1016/j.mehy.2020.109740. [PMID: 32305810] - Christoph Dorn, Selina Schießer, Beatrix Wulkersdorfer, Florian Hitzenbichler, Martin G Kees, Markus Zeitlinger. Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Pay attention to physiological conditions when using ultrafiltration.
Biomedical chromatography : BMC.
2020 Jun; 34(6):e4820. doi:
10.1002/bmc.4820. [PMID: 32115736] - Jinyan Gong, Jiong Li, Haina Yuan, Bingquan Chu, Weijie Lin, Qingwen Cao, Qiqi Zhao, Ruosi Fang, Ling Li, Gongnian Xiao. Determination of four nitrofuran metabolites in gelatin Chinese medicine using dispersive solid phase extraction and pass-through solid phase extraction coupled to ultra high performance liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 Jun; 1146(?):122018. doi:
10.1016/j.jchromb.2020.122018. [PMID: 32334390] - Junzhen Wu, Guoying Cao, Hailan Wu, Yuancheng Chen, Beining Guo, Xiaojie Wu, Jicheng Yu, Kanhong Ni, Jin Qian, Li Wang, Jufang Wu, Yu Wang, Hong Yuan, Jing Zhang, Yuewen Xi. Evaluation of the Effect of Contezolid (MRX-I) on the Corrected QT Interval in a Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study in Healthy Chinese Volunteers.
Antimicrobial agents and chemotherapy.
2020 05; 64(6):. doi:
10.1128/aac.02158-19. [PMID: 32229495] - Li-Xing Nie, Yan-Lin Wu, Zhong Dai, Shuang-Cheng Ma. Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action.
Journal of ethnopharmacology.
2020 Apr; 251(?):112550. doi:
10.1016/j.jep.2020.112550. [PMID: 31918015] - Ewa Szpyrka, Magdalena Słowik-Borowiec, Paulina Książek, Aneta Zwolak, Magdalena Podbielska. The difference in dissipation of clomazone and metazachlor in soil under field and laboratory conditions and their uptake by plants.
Scientific reports.
2020 02; 10(1):3747. doi:
10.1038/s41598-020-60720-0. [PMID: 32111959] - Lara M Almeida, Anthony Gaca, Paulo M Bispo, François Lebreton, Jose T Saavedra, Rafael A Silva, Irinaldo D Basílio-Júnior, Felipe M Zorzi, Pedro H Filsner, Andrea M Moreno, Michael S Gilmore. Coexistence of the Oxazolidinone Resistance-Associated Genes cfr and optrA in Enterococcus faecalis From a Healthy Piglet in Brazil.
Frontiers in public health.
2020; 8(?):518. doi:
10.3389/fpubh.2020.00518. [PMID: 33102417] - Farshid Ali Naghi Zadeh Khezri, C S R Lakshmi, Rama Bukka, Malviya Nidhi, Shachindra L Nargund. Pharmacokinetic study and brain tissue analysis of Zolmitriptan loaded chitosan nanoparticles in rats by LC-MS method.
International journal of biological macromolecules.
2020 Jan; 142(?):52-62. doi:
10.1016/j.ijbiomac.2019.08.236. [PMID: 31593739] - Masayoshi Yamaguchi, Robert M Levy. Metaxalone Suppresses Production of Inflammatory Cytokines Associated with Painful Conditions in Mouse Macrophages RAW264.7 Cells in Vitro: Synergistic Effect with β-caryophyllene.
Current molecular medicine.
2020; 20(8):643-652. doi:
10.2174/1566524020666200217102508. [PMID: 32065089] - Jason Barricklow, Joseph Tweed, Christopher L Holliman, Ragu Ramanathan. Evaluation of OptiFlow™-MS/MS for bioanalysis of pharmaceutical drugs and metabolites.
Bioanalysis.
2020 Jan; 12(1):23-34. doi:
10.4155/bio-2019-0250. [PMID: 31849261] - Randa Hanie Awadeen, Mariza Fouad Boughdady, Mahasen Mohamed Meshali. Quality by Design Approach for Preparation of Zolmitriptan/Chitosan Nanostructured Lipid Carrier Particles - Formulation and Pharmacodynamic Assessment.
International journal of nanomedicine.
2020; 15(?):8553-8568. doi:
10.2147/ijn.s274352. [PMID: 33173292] - Kaoru Kobayshi, Yoshikazu Abe, Asuka Kawai, Takao Furihata, Hiroshi Harada, Takuro Endo, Hiroo Takeda. Human mass balance, pharmacokinetics and metabolism of rovatirelin and identification of its metabolic enzymes in vitro.
Xenobiotica; the fate of foreign compounds in biological systems.
2019 Dec; 49(12):1434-1446. doi:
10.1080/00498254.2019.1580796. [PMID: 30747023] - Douglas G Johns, Sheng-Ping Wang, Raymond Rosa, James Hubert, Suoyu Xu, Ying Chen, Thomas Bateman, Robert O Blaustein. Impact of drug distribution into adipose on tissue function: The cholesteryl ester transfer protein (CETP) inhibitor anacetrapib as a test case.
Pharmacology research & perspectives.
2019 12; 7(6):e00543. doi:
10.1002/prp2.543. [PMID: 31832204] - Junzhen Wu, Kun Wang, Yuancheng Chen, Hong Yuan, Li Li, Jing Zhang. Concentration-response modeling of ECG data from early-phase clinical studies to assess QT prolongation risk of contezolid (MRX-I), an oxazolidinone antibacterial agent.
Journal of pharmacokinetics and pharmacodynamics.
2019 12; 46(6):531-541. doi:
10.1007/s10928-019-09650-7. [PMID: 31410633] - Zhuang-Zhuang Kang, Chang-Wei Lei, Ling-Han Kong, Yu-Long Wang, Xiao-Lan Ye, Bo-Heng Ma, Xue-Chun Wang, Cui Li, Yu Zhang, Hong-Ning Wang. Detection of transferable oxazolidinone resistance determinants in Enterococcus faecalis and Enterococcus faecium of swine origin in Sichuan Province, China.
Journal of global antimicrobial resistance.
2019 12; 19(?):333-337. doi:
10.1016/j.jgar.2019.05.021. [PMID: 31136832] - Ben J Wu, Yue Li, Kwok-Leung Ong, Yidan Sun, Douglas Johns, Philip J Barter, Kerry-Anne Rye. The Cholesteryl Ester Transfer Protein Inhibitor, des-Fluoro-Anacetrapib, Prevents Vein Bypass-induced Neointimal Hyperplasia in New Zealand White Rabbits.
Scientific reports.
2019 11; 9(1):16183. doi:
10.1038/s41598-019-52510-0. [PMID: 31700015] - Shan Wang, Yun Li, Feng Xue, Jian Liu, Weiwei Yang, Jia Zhang, Martin Glenschek-Sieberth, Yuan Lyu. Comparative in vitro potency and kill curve activity of tedizolid and linezolid against Gram-positive bacteria isolated from Chinese hospitalized patients in 2013-2016.
Journal of chemotherapy (Florence, Italy).
2019 Oct; 31(6):313-319. doi:
10.1080/1120009x.2019.1623968. [PMID: 31215343] - Liqiang Gu, Munong Ma, Yuan Zhang, Lijiang Zhang, Sheng Zhang, Mincong Huang, Majuan Zhang, Yanfei Xin, Gaoli Zheng, Suhong Chen. Comparative pharmacokinetics of tedizolid in rat plasma and cerebrospinal fluid.
Regulatory toxicology and pharmacology : RTP.
2019 Oct; 107(?):104420. doi:
10.1016/j.yrtph.2019.104420. [PMID: 31295511] - Jinhang Li, Yanhong Shi, Yan Xu, Li Yang, Zhengtao Wang, Han Han, Rui Wang. Metabolic profiles and pharmacokinetics of goitrin in rats through liquid chromatography combined with electrospray ionization-tandem mass spectrometry.
Biomedical chromatography : BMC.
2019 Oct; 33(10):e4606. doi:
10.1002/bmc.4606. [PMID: 31132308] - Sneha M Dixit, Mohd Ahsan, Sanjib Senapati. Steering the Lipid Transfer To Unravel the Mechanism of Cholesteryl Ester Transfer Protein Inhibition.
Biochemistry.
2019 09; 58(36):3789-3801. doi:
10.1021/acs.biochem.9b00301. [PMID: 31418269] - Jinhu Huang, Mengli Wang, Yi Gao, Li Chen, Liping Wang. Emergence of plasmid-mediated oxazolidinone resistance gene poxtA from CC17 Enterococcus faecium of pig origin.
The Journal of antimicrobial chemotherapy.
2019 09; 74(9):2524-2530. doi:
10.1093/jac/dkz250. [PMID: 31236590] - Mwila Mulubwa, Pierre Mugabo. Steady-state population pharmacokinetics of terizidone and its metabolite cycloserine in patients with drug-resistant tuberculosis.
British journal of clinical pharmacology.
2019 09; 85(9):1946-1956. doi:
10.1111/bcp.13975. [PMID: 31046167] - Vimal Maurya, Pranesh Kumar, Sreemoyee Chakraborti, Ashok K Singh, Archana S Bhadauria, Umesh Kumar, Dinesh Kumar, Arnab Pramanik, Biswajit Saha, Venkatesh Kumar R, Sunil Babu Gosipatala, Bolay Bhattachariya, Biswanath Maity, Sudipta Saha. Zolmitriptan attenuates hepatocellular carcinoma via activation of caspase mediated apoptosis.
Chemico-biological interactions.
2019 Aug; 308(?):120-129. doi:
10.1016/j.cbi.2019.05.033. [PMID: 31129132] - Dandara Fidélis Escoto, Mateus Cristofary Gayer, Matheus Chimelo Bianchini, Geovana da Cruz Pereira, Rafael Roehrs, Elton L G Denardin. Use of Pistia stratiotes for phytoremediation of water resources contaminated by clomazone.
Chemosphere.
2019 Jul; 227(?):299-304. doi:
10.1016/j.chemosphere.2019.04.013. [PMID: 30999171] - Junzhen Wu, Hailan Wu, Yu Wang, Yuancheng Chen, Beining Guo, Guoying Cao, Xiaojie Wu, Jicheng Yu, Jufang Wu, Demei Zhu, Yan Guo, Hong Yuan, Fupin Hu, Jing Zhang. Tolerability and Pharmacokinetics of Contezolid at Therapeutic and Supratherapeutic Doses in Healthy Chinese Subjects, and Assessment of Contezolid Dosing Regimens Based on Pharmacokinetic/Pharmacodynamic Analysis.
Clinical therapeutics.
2019 06; 41(6):1164-1174.e4. doi:
10.1016/j.clinthera.2019.04.025. [PMID: 31126694] - Feng Guo, Satoshi Iwakami, Takuya Yamaguchi, Akira Uchino, Yukari Sunohara, Hiroshi Matsumoto. Role of CYP81A cytochrome P450s in clomazone metabolism in Echinochloa phyllopogon.
Plant science : an international journal of experimental plant biology.
2019 Jun; 283(?):321-328. doi:
10.1016/j.plantsci.2019.02.010. [PMID: 31128703] - Seok Hyeon Na, Dong Chan Moon, Myeong-Ja Choi, Sun-Joo Oh, Dae-Young Jung, Hee Young Kang, Bang-Hun Hyun, Suk-Kyung Lim. Detection of oxazolidinone and phenicol resistant enterococcal isolates from duck feces and carcasses.
International journal of food microbiology.
2019 Mar; 293(?):53-59. doi:
10.1016/j.ijfoodmicro.2019.01.002. [PMID: 30640000] - Douglas G Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman, Robert O Blaustein. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes.
Drug metabolism and disposition: the biological fate of chemicals.
2019 03; 47(3):227-233. doi:
10.1124/dmd.118.084525. [PMID: 30567880] - Kaoru Kobayashi, Yoshikazu Abe, Hiroshi Harada, Emiko Oota, Takuro Endo, Hiroo Takeda. Non-clinical pharmacokinetic profiles of rovatirelin, an orally available thyrotropin-releasing hormone analogue.
Xenobiotica; the fate of foreign compounds in biological systems.
2019 Jan; 49(1):106-119. doi:
10.1080/00498254.2017.1423130. [PMID: 29300135] - Yong-Soon Cho, Hyeong-Seok Lim, Sungpil Han, Seok Kyu Yoon, Hyungsub Kim, Young Lag Cho, Hee-Sook Nam, Kyun-Seop Bae. Single-dose Intravenous Safety, Tolerability, and Pharmacokinetics and Absolute Bioavailability of LCB01-0371.
Clinical therapeutics.
2019 01; 41(1):92-106. doi:
10.1016/j.clinthera.2018.11.009. [PMID: 30559004] - John O'Donnell, Ken Lawrence, Karthick Vishwanathan, Vinayak Hosagrahara, John P Mueller. Single-Dose Pharmacokinetics, Excretion, and Metabolism of Zoliflodacin, a Novel Spiropyrimidinetrione Antibiotic, in Healthy Volunteers.
Antimicrobial agents and chemotherapy.
2019 01; 63(1):. doi:
10.1128/aac.01808-18. [PMID: 30373802] - Pengqiang Du, Xiaohu Wu, Jun Xu, Fengshou Dong, Xingang Liu, Ying Zhang, Yongquan Zheng. Clomazone influence soil microbial community and soil nitrogen cycling.
The Science of the total environment.
2018 Dec; 644(?):475-485. doi:
10.1016/j.scitotenv.2018.06.214. [PMID: 29990898] - Yong-Soon Cho, Hyeong-Seok Lim, Young Lag Cho, Hee-Sook Nam, Kyun-Seop Bae. Multiple-dose Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral LCB01-0371 in Healthy Male Volunteers.
Clinical therapeutics.
2018 12; 40(12):2050-2064. doi:
10.1016/j.clinthera.2018.10.007. [PMID: 30420289] - Lin Zhu, Thao Luu, Christopher H Emfinger, Bryan A Parks, Jeanne Shi, Elijah Trefts, Fenghua Zeng, Zsuzsanna Kuklenyik, Raymond C Harris, David H Wasserman, Sergio Fazio, John M Stafford. CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet.
Diabetes.
2018 12; 67(12):2494-2506. doi:
10.2337/db18-0474. [PMID: 30213825] - Rajesh Krishna, Ferdous Gheyas, Christy Corr, Josee Cote, Yang Liu, John Wagner, David E Gutstein. Pharmacokinetics and Pharmacodynamics of Anacetrapib in Black and White Healthy Subjects.
Journal of clinical pharmacology.
2018 12; 58(12):1578-1585. doi:
10.1002/jcph.1287. [PMID: 30029292] - Mwila Mulubwa, Pierre Mugabo. Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.
Biomedical chromatography : BMC.
2018 Nov; 32(11):e4325. doi:
10.1002/bmc.4325. [PMID: 29947117] - Yamato Sano, Tadahaya Mizuno, Tatsuki Mochizuki, Yasuo Uchida, Mina Umetsu, Tetsuya Terasaki, Hiroyuki Kusuhara. Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier.
Drug metabolism and disposition: the biological fate of chemicals.
2018 11; 46(11):1767-1775. doi:
10.1124/dmd.118.081877. [PMID: 30154106] - Philip J Barter, Blake J Cochran, Kerry-Anne Rye. CETP inhibition, statins and diabetes.
Atherosclerosis.
2018 11; 278(?):143-146. doi:
10.1016/j.atherosclerosis.2018.09.033. [PMID: 30278356] - Niels Agerbirk, Annemarie Matthes, Pernille Ø Erthmann, Luisa Ugolini, Susanna Cinti, Eleni Lazaridi, Jean-Marc Nuzillard, Caroline Müller, Søren Bak, Patrick Rollin, Luca Lazzeri. Glucosinolate turnover in Brassicales species to an oxazolidin-2-one, formed via the 2-thione and without formation of thioamide.
Phytochemistry.
2018 Sep; 153(?):79-93. doi:
10.1016/j.phytochem.2018.05.006. [PMID: 29886160] - Zhiwei Yang, Yang Cao, Dongxiao Hao, Xiaohui Yuan, Lei Zhang, Shengli Zhang. Binding profiles of cholesterol ester transfer protein with current inhibitors: a look at mechanism and drawback.
Journal of biomolecular structure & dynamics.
2018 Aug; 36(10):2567-2580. doi:
10.1080/07391102.2017.1363661. [PMID: 28777919] - Yong-Soon Cho, Hyeong-Seok Lim, Shi-Hyang Lee, Young Lag Cho, Hee-Sook Nam, Kyun-Seop Bae. Pharmacokinetics, Pharmacodynamics, and Tolerability of Single-Dose Oral LCB01-0371, a Novel Oxazolidinone with Broad-Spectrum Activity, in Healthy Volunteers.
Antimicrobial agents and chemotherapy.
2018 07; 62(7):. doi:
10.1128/aac.00451-18. [PMID: 29712654] - Yanhong Shi, Cheng Zheng, Jinhang Li, Li Yang, Zhengtao Wang, Rui Wang. Separation and Quantification of Four Main Chiral Glucosinolates in Radix Isatidis and Its Granules Using High-Performance Liquid Chromatography/Diode Array Detector Coupled with Circular Dichroism Detection.
Molecules (Basel, Switzerland).
2018 May; 23(6):. doi:
10.3390/molecules23061305. [PMID: 29844266] - Yusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi, Tomohiro Nishizawa. Generation and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain-Fused Anticalin Protein.
The Journal of pharmacology and experimental therapeutics.
2018 05; 365(2):368-378. doi:
10.1124/jpet.117.246652. [PMID: 29463608] - Sheila A Doggrell. Cardiovascular outcomes trial with anacetrapib in subjects with high cardiovascular risk - are major benefits REVEALed?.
Expert opinion on pharmacotherapy.
2018 Apr; 19(6):611-615. doi:
10.1080/14656566.2018.1448061. [PMID: 29498299] - Matthieu Grégoire, Julia Brochard Libois, Denis Waast, Benjamin Gaborit, Marc Dauty, Guillaume Deslandes, Eric Dailly, Sophie Touchais, David Boutoille, Nicolas Grégoire, William Couet. Pharmacokinetics of Tedizolid in an Obese Patient after Bariatric Surgery.
Antimicrobial agents and chemotherapy.
2018 04; 62(4):. doi:
10.1128/aac.02432-17. [PMID: 29378714] - Mekki Bensaci, Shawn Flanagan, Taylor Sandison. Determination of Tedizolid susceptibility interpretive criteria for gram-positive pathogens according to clinical and laboratory standards institute guidelines.
Diagnostic microbiology and infectious disease.
2018 Mar; 90(3):214-220. doi:
10.1016/j.diagmicrobio.2017.10.023. [PMID: 29277464] - L P Zhu, J P Wang, X M Ding, S P Bai, Q F Zeng, Z W Su, Y Xuan, K Y Zhang. The Deposition and Elimination of Glucosinolate Metabolites Derived from Rapeseed Meal in Eggs of Laying Hens.
Journal of agricultural and food chemistry.
2018 Feb; 66(6):1560-1568. doi:
10.1021/acs.jafc.7b05782. [PMID: 29345135] - Rajesh Krishna, Ferdous Gheyas, Yang Liu, Josee Cote, Omar Laterza, Jon L Ruckle, John A Wagner, Andrew E Denker. Pharmacokinetics and Pharmacodynamics of Anacetrapib Following Single Doses in Healthy, Young Japanese and White Male Subjects.
Journal of clinical pharmacology.
2018 02; 58(2):254-262. doi:
10.1002/jcph.1004. [PMID: 28884824] - Xiaojie Wu, Yunfei Li, Jing Zhang, Yingyuan Zhang, Jicheng Yu, Guoying Cao, Yuancheng Chen, Beining Guo, Yaoguo Shi, Jun Huang, Yuran Cao, Xiaofang Liu, Jufang Wu, Mikhail Fedorovich Gordeev, Hong Yuan, Wen Wang. Short-term Safety, Tolerability, and Pharmacokinetics of MRX-I, an Oxazolidinone Antibacterial Agent, in Healthy Chinese Subjects.
Clinical therapeutics.
2018 02; 40(2):322-332.e5. doi:
10.1016/j.clinthera.2017.12.017. [PMID: 29398160] - Alan R Tall, Daniel J Rader. Trials and Tribulations of CETP Inhibitors.
Circulation research.
2018 01; 122(1):106-112. doi:
10.1161/circresaha.117.311978. [PMID: 29018035] - R Court, L Wiesner, A Stewart, N de Vries, J Harding, G Maartens, T Gumbo, H McIlleron. Steady state pharmacokinetics of cycloserine in patients on terizidone for multidrug-resistant tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.
2018 01; 22(1):30-33. doi:
10.5588/ijtld.17.0475. [PMID: 29297422] - Sean M Stainton, Marguerite L Monogue, Arlinda Baummer-Carr, Ashley K Shepard, James F Nugent, Joseph L Kuti, David P Nicolau. Comparative Assessment of Tedizolid Pharmacokinetics and Tissue Penetration between Diabetic Patients with Wound Infections and Healthy Volunteers via In Vivo Microdialysis.
Antimicrobial agents and chemotherapy.
2018 01; 62(1):. doi:
10.1128/aac.01880-17. [PMID: 29109162] - Jung Sunwoo, Yu Kyong Kim, Yewon Choi, Kyung-Sang Yu, Heesook Nam, Young Lag Cho, Seonghae Yoon, Jae-Yong Chung. Effect of food on the pharmacokinetic characteristics of a single oral dose of LCB01-0371, a novel oxazolidinone antibiotic.
Drug design, development and therapy.
2018; 12(?):1707-1714. doi:
10.2147/dddt.s155657. [PMID: 29928114] - Meike Siebers, Thomas Rohr, Marina Ventura, Vadim Schütz, Stephan Thies, Filip Kovacic, Karl-Erich Jaeger, Martin Berg, Peter Dörmann, Margot Schulz. Disruption of microbial community composition and identification of plant growth promoting microorganisms after exposure of soil to rapeseed-derived glucosinolates.
PloS one.
2018; 13(7):e0200160. doi:
10.1371/journal.pone.0200160. [PMID: 29969500] - Ben J Wu, Yue Li, Kwok L Ong, Yidan Sun, Sudichhya Shrestha, Liming Hou, Douglas Johns, Philip J Barter, Kerry-Anne Rye. Reduction of In-Stent Restenosis by Cholesteryl Ester Transfer Protein Inhibition.
Arteriosclerosis, thrombosis, and vascular biology.
2017 12; 37(12):2333-2341. doi:
10.1161/atvbaha.117.310051. [PMID: 29025709] - Liwei He, Fangtian Fan, Xianbang Hou, Hongyan Wu, Juan Wang, Huiqin Xu, Yun Sun. 4(3H)-Quinazolone regulates innate immune signaling upon respiratory syncytial virus infection by moderately inhibiting the RIG-1 pathway in RAW264.7 cell.
International immunopharmacology.
2017 Nov; 52(?):245-252. doi:
10.1016/j.intimp.2017.09.010. [PMID: 28957692] - R Krishna, F Gheyas, Y Liu, D R Hagen, B Walker, A Chawla, J Cote, R O Blaustein, D E Gutstein. Chronic Administration of Anacetrapib Is Associated With Accumulation in Adipose and Slow Elimination.
Clinical pharmacology and therapeutics.
2017 Nov; 102(5):832-840. doi:
10.1002/cpt.700. [PMID: 28380664] - Luis Masana. Results of the REVEAL study. Why Should we not welcome a new lipid lowering agent?.
Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis.
2017 Nov; 29(6):278-279. doi:
10.1016/j.arteri.2017.10.002. [PMID: 29173491] - Sally E Wenzel, Yulia Y Tyurina, Jinming Zhao, Claudette M St Croix, Haider H Dar, Gaowei Mao, Vladimir A Tyurin, Tamil S Anthonymuthu, Alexandr A Kapralov, Andrew A Amoscato, Karolina Mikulska-Ruminska, Indira H Shrivastava, Elizabeth M Kenny, Qin Yang, Joel C Rosenbaum, Louis J Sparvero, David R Emlet, Xiaoyan Wen, Yoshinori Minami, Feng Qu, Simon C Watkins, Theodore R Holman, Andrew P VanDemark, John A Kellum, Ivet Bahar, Hülya Bayır, Valerian E Kagan. PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.
Cell.
2017 Oct; 171(3):628-641.e26. doi:
10.1016/j.cell.2017.09.044. [PMID: 29053969] - Wangda Zhou, Jianguo Li, Bruce Birmingham, Hongmei Xu, Stefan Lillieborg, Diansong Zhou, Nidal Al-Huniti. Population Pharmacokinetic Analysis of Zolmitriptan and Its Metabolite in Adults and Adolescents to Support Dose Selection in Children With Migraine.
Journal of clinical pharmacology.
2017 10; 57(10):1258-1267. doi:
10.1002/jcph.935. [PMID: 28581633] - Juliane Silberschmidt Freitas, Andreia Arantes Felício, Fabrício Barreto Teresa, Eduardo Alves de Almeida. Combined effects of temperature and clomazone (Gamit®) on oxidative stress responses and B-esterase activity of Physalaemus nattereri (Leiuperidae) and Rhinella schneideri (Bufonidae) tadpoles.
Chemosphere.
2017 Oct; 185(?):548-562. doi:
10.1016/j.chemosphere.2017.07.061. [PMID: 28719874] - Tiffany Thomas, Haihong Zhou, Wahida Karmally, Rajasekhar Ramakrishnan, Stephen Holleran, Yang Liu, Patricia Jumes, John A Wagner, Brian Hubbard, Stephen F Previs, Thomas Roddy, Amy O Johnson-Levonas, David E Gutstein, Santica M Marcovina, Daniel J Rader, Henry N Ginsberg, John S Millar, Gissette Reyes-Soffer. CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects.
Arteriosclerosis, thrombosis, and vascular biology.
2017 09; 37(9):1770-1775. doi:
10.1161/atvbaha.117.309549. [PMID: 28729361] - Harilal Patel, Prakash Patel, Nirav Modi, Shaival Shah, Ashok Ghoghari, Bhavesh Variya, Ritu Laddha, Dipesh Baradia, Nitin Dobaria, Pavak Mehta, Nuggehally R Srinivas. One should avoid retro-orbital pharmacokinetic sample collections for intranasal dosing in rats: Illustration of spurious pharmacokinetics generated for anti-migraine drugs zolmitriptan and eletriptan.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2017 Aug; 106(?):87-93. doi:
10.1016/j.ejps.2017.05.044. [PMID: 28549679]