beta-Chlordane (BioDeep_00000009739)

 

Secondary id: BioDeep_00001028412, BioDeep_00001871673

human metabolite blood metabolite


代谢物信息卡片


1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene

化学式: C10H6Cl8 (405.79777160000003)
中文名称: 氯丹农药溶液, 反式氯丹, 顺-氯丹, 氯丹
谱图信息: 最多检出来源 Homo sapiens(blood) 92.86%

分子结构信息

SMILES: C1C2C(C(C1Cl)Cl)C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C10H6Cl8/c11-3-1-2-4(5(3)12)9(16)7(14)6(13)8(2,15)10(9,17)18/h2-5H,1H2

描述信息

D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals

同义名列表

14 个代谢物同义名

1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene; 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindan; 1,2,4,5,6,7,10,10-Octachloro-4,7,8,9-tetrahydro-4,7-methyleneindane; 1,3,4,7,8,9,10,10-octachlorotricyclo[5.2.1.0^{2,6}]dec-8-ene; 1,3,4,7,8,9,10,10-Octachlorotricyclo[5.2.1.0(2,6)]dec-8-ene; chlordan technical mixture pestanal; gamma Chlordane; trans-chlordane; gamma-Chlordane; beta-Chlordane; α-Chlordane; Chlorindan; chlordane; Chlordan



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Boyang Li, Luxi Chen, Feng Li, Qiaoyao Cao, Chenyan Yan, Xin Wu, Kexin Wang, Mingjiang Wu, Yitian Gao, Haibin Tong. Chlordane exposure impairs the growth and behavior of Drosophila. Ecotoxicology and environmental safety. 2024 Jan; 270(?):115903. doi: 10.1016/j.ecoenv.2023.115903. [PMID: 38176184]
  • Jan Ove Bustnes, Bård-Jørgen Bårdsen, Børge Moe, Dorte Herzke, Manuel Ballesteros, Anette Fenstad, Katrine Borgå, Ingjerd S Krogseth, Igor Eulaers, Lovise P Skogeng, Geir W Gabrielsen, Sveinn-Are Hanssen. Impacts of a warming climate on concentrations of organochlorines in a fasting high arctic marine bird: Direct vs. indirect effects?. The Science of the total environment. 2023 Oct; 908(?):168096. doi: 10.1016/j.scitotenv.2023.168096. [PMID: 37914131]
  • Jianzhu Luo, Walter H Watson, Tyler C Gripshover, Zayna Qaissi, Banrida Wahlang. Sex-specific effects of acute chlordane exposure in the context of steatotic liver disease, energy metabolism and endocrine disruption. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Sep; 180(?):114024. doi: 10.1016/j.fct.2023.114024. [PMID: 37666290]
  • Jungmi Choi, Yukiko Fujii, Zhaoqing Lyu, Hatasu Kobayashi, Tomoko Fujitani, Kouji H Harada. Chlorinated persistent organic pollutants in human breast milk in the Miyagi Prefecture disaster-affected area 1 year after the Great East Japan Earthquake of 2011. Environmental health and preventive medicine. 2023; 28(?):27. doi: 10.1265/ehpm.22-00260. [PMID: 37150618]
  • Xueke Liu, Yaofeng Fang, Xiaoran Ma, Peize Li, Peng Wang, Zhiqiang Zhou, Donghui Liu. Metabolomic profiling to assess the effects of chlordanes and its bioaccumulation characteristics in chicken embryo. Chemosphere. 2022 Dec; 308(Pt 3):136580. doi: 10.1016/j.chemosphere.2022.136580. [PMID: 36155011]
  • Qifang Wu, Xueting Du, Xucong Feng, Huimin Cheng, Yingjun Chen, Chenying Lu, Mingjiang Wu, Haibin Tong. Chlordane exposure causes developmental delay and metabolic disorders in Drosophila melanogaster. Ecotoxicology and environmental safety. 2021 Dec; 225(?):112739. doi: 10.1016/j.ecoenv.2021.112739. [PMID: 34481351]
  • Seblework Mekonen, Mohammedgezali Ibrahim, Higemengist Astatkie, Aynalem Abreha. Exposure to organochlorine pesticides as a predictor to breast cancer: A case-control study among Ethiopian women. PloS one. 2021; 16(9):e0257704. doi: 10.1371/journal.pone.0257704. [PMID: 34555072]
  • Xu Han, Feng Zhang, Lingling Meng, Yuedong Xu, Yingming Li, An Li, Mary E Turyk, Ruiqiang Yang, Pu Wang, Jianqing Zhang, Qinghua Zhang, Guibin Jiang. Exposure to organochlorine pesticides and the risk of type 2 diabetes in the population of East China. Ecotoxicology and environmental safety. 2020 Mar; 190(?):110125. doi: 10.1016/j.ecoenv.2019.110125. [PMID: 31887706]
  • Lawrence S Engel, Emily C Zabor, Jaya Satagopan, Anders Widell, Nathaniel Rothman, Thomas R O'Brien, Mingdong Zhang, Stephen K Van Den Eeden, Tom K Grimsrud. Prediagnostic serum organochlorine insecticide concentrations and primary liver cancer: A case-control study nested within two prospective cohorts. International journal of cancer. 2019 11; 145(9):2360-2371. doi: 10.1002/ijc.32175. [PMID: 30701531]
  • Bryan A Bassig, Lawrence S Engel, Hilde Langseth, Tom K Grimsrud, Kenneth P Cantor, Roel Vermeulen, Mark P Purdue, Dana Boyd Barr, Jason Y Y Wong, Aaron Blair, Nathaniel Rothman, Qing Lan. Pre-diagnostic serum concentrations of organochlorines and risk of acute myeloid leukemia: A nested case-control study in the Norwegian Janus Serum Bank Cohort. Environment international. 2019 04; 125(?):229-235. doi: 10.1016/j.envint.2019.01.066. [PMID: 30721827]
  • Edward C Meek, Dana Dale Jones, J Allen Crow, Robert W Wills, William H Cooke, Janice E Chambers. Association of serum levels of p,p'- Dichlorodiphenyldichloroethylene (DDE) with type 2 diabetes in African American and Caucasian adult men from agricultural (Delta) and non-agricultural (non-Delta) regions of Mississippi. Journal of toxicology and environmental health. Part A. 2019; 82(6):387-400. doi: 10.1080/15287394.2019.1610678. [PMID: 31064277]
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  • George Eli Howell, Erin McDevitt, Lucie Henein, Charlee Mulligan, Darian Young. Alterations in cellular lipid metabolism produce neutral lipid accumulation following exposure to the organochlorine compound trans-nonachlor in rat primary hepatocytes. Environmental toxicology. 2018 Sep; 33(9):962-971. doi: 10.1002/tox.22583. [PMID: 29964320]
  • Tomasz Maciej Ciesielski, Christian Sonne, Ingunn Ormbostad, Jon Aars, Elisabeth Lie, Jenny Bytingsvik, Bjørn Munro Jenssen. Effects of biometrics, location and persistent organic pollutants on blood clinical-chemical parameters in polar bears (Ursus maritimus) from Svalbard, Norway. Environmental research. 2018 08; 165(?):387-399. doi: 10.1016/j.envres.2018.04.026. [PMID: 29860211]
  • B González-Alzaga, M Lacasaña, A F Hernández, J P Arrebola, I López-Flores, F Artacho-Cordón, J P Bonde, N Olea, C Aguilar-Garduño. Serum concentrations of organochlorine compounds and predictors of exposure in children living in agricultural communities from South-Eastern Spain. Environmental pollution (Barking, Essex : 1987). 2018 Jun; 237(?):685-694. doi: 10.1016/j.envpol.2017.10.109. [PMID: 29129429]
  • Risa Kakimoto, Masayoshi Ichiba, Akiko Matsumoto, Kunihiko Nakai, Nozomi Tatsuta, Miyuki Iwai-Shimada, Momoko Ishiyama, Noriko Ryuda, Takashi Someya, Ieyasu Tokumoto, Daisuke Ueno. Variability and reliability of POP concentrations in multiple breast milk samples collected from the same mothers. Environmental science and pollution research international. 2018 Jun; 25(17):16309-16315. doi: 10.1007/s11356-017-1031-x. [PMID: 29332276]
  • Josiah E Hardesty, Laila Al-Eryani, Banrida Wahlang, K Cameron Falkner, Hongxue Shi, Jian Jin, Brad J Vivace, Brian P Ceresa, Russell A Prough, Matthew C Cave. Epidermal Growth Factor Receptor Signaling Disruption by Endocrine and Metabolic Disrupting Chemicals. Toxicological sciences : an official journal of the Society of Toxicology. 2018 04; 162(2):622-634. doi: 10.1093/toxsci/kfy004. [PMID: 29329451]
  • Mohamed Abou-Elwafa Abdallah, Amen Hamdy Zaky, Adrian Covaci. Levels and profiles of organohalogenated contaminants in human blood from Egypt. Chemosphere. 2017 Jun; 176(?):266-272. doi: 10.1016/j.chemosphere.2017.02.139. [PMID: 28273534]
  • Paula Méndez-Fernandez, Paola Galluzzi Polesi, Satie Taniguchi, Marcos C de O Santos, Rosalinda C Montone. Validating the use of biopsy sampling in contamination assessment studies of small cetaceans. Marine pollution bulletin. 2016 Jun; 107(1):364-369. doi: 10.1016/j.marpolbul.2016.04.021. [PMID: 27113024]
  • Humberto Parada, Mary S Wolff, Lawrence S Engel, Alexandra J White, Sybil M Eng, Rebecca J Cleveland, Nikhil K Khankari, Susan L Teitelbaum, Alfred I Neugut, Marilie D Gammon. Organochlorine insecticides DDT and chlordane in relation to survival following breast cancer. International journal of cancer. 2016 Feb; 138(3):565-75. doi: 10.1002/ijc.29806. [PMID: 26285160]
  • Abdallah Fikry A Mahmoud, Yoshinori Ikenaka, Yared B Yohannes, Wageh S Darwish, Elsaid A Eldaly, Alaa Eldin M A Morshdy, Shouta M M Nakayama, Hazuki Mizukawa, Mayumi Ishizuka. Distribution and health risk assessment of organochlorine pesticides (OCPs) residue in edible cattle tissues from northeastern part of Egypt: High accumulation level of OCPs in tongue. Chemosphere. 2016 Feb; 144(?):1365-71. doi: 10.1016/j.chemosphere.2015.10.016. [PMID: 26492422]
  • Lida Dimitriadou, Govindan Malarvannan, Adrian Covaci, Eleni Iossifidou, John Tzafettas, Vassiliki Zournatzi-Koiou, Olga-Ioanna Kalantzi. Levels and profiles of brominated and chlorinated contaminants in human breast milk from Thessaloniki, Greece. The Science of the total environment. 2016 Jan; 539(?):350-358. doi: 10.1016/j.scitotenv.2015.08.137. [PMID: 26367190]
  • Walter Vetter, Vanessa Gall, Karl Skírnisson. Polyhalogenated compounds (PCBs, chlordanes, HCB and BFRs) in four polar bears (Ursus maritimus) that swam malnourished from East Greenland to Iceland. The Science of the total environment. 2015 Nov; 533(?):290-6. doi: 10.1016/j.scitotenv.2015.07.011. [PMID: 26172596]
  • Anne-Mary Lewis-Mikhael, Rocío Olmedo-Requena, Virginia Martínez-Ruiz, Aurora Bueno-Cavanillas, José Juan Jiménez-Moleón. Organochlorine pesticides and prostate cancer, Is there an association? A meta-analysis of epidemiological evidence. Cancer causes & control : CCC. 2015 Oct; 26(10):1375-92. doi: 10.1007/s10552-015-0643-z. [PMID: 26245248]
  • Sunmi Kim, Jeongim Park, Hai-Joong Kim, Jeong Jae Lee, Gyuyeon Choi, Sooran Choi, Sungjoo Kim, Su Young Kim, Duk Hee Lee, Hyo-Bang Moon, Sungkyoon Kim, Kyungho Choi. Association between Several Persistent Organic Pollutants in Serum and Adipokine Levels in Breast Milk among Lactating Women of Korea. Environmental science & technology. 2015 Jul; 49(13):8033-40. doi: 10.1021/acs.est.5b00520. [PMID: 26054256]
  • Hyun-Kyung Lee, Yunsun Jeong, Sunggyu Lee, Woochang Jeong, Eun-Jung Choy, Chang-Keun Kang, Won-Chan Lee, Sang-Jo Kim, Hyo-Bang Moon. Persistent organochlorines in 13 shark species from offshore and coastal waters of Korea: Species-specific accumulation and contributing factors. Ecotoxicology and environmental safety. 2015 May; 115(?):195-202. doi: 10.1016/j.ecoenv.2015.02.021. [PMID: 25704278]
  • Genta Yasunaga, Yoshihiro Fujise, Ryoko Zenitani, Shinsuke Tanabe, Hidehiro Kato. Spatial and temporal variation of PCBs and organochlorine pesticides in the Antarctic minke whales, Balaenoptera bonaerensis, in the period 1987-2005. Chemosphere. 2015 May; 126(?):11-7. doi: 10.1016/j.chemosphere.2014.12.074. [PMID: 25637712]
  • Se-A Kim, Yu-Mi Lee, Ho-Won Lee, David R Jacobs, Duk-Hee Lee. Greater cognitive decline with aging among elders with high serum concentrations of organochlorine pesticides. PloS one. 2015; 10(6):e0130623. doi: 10.1371/journal.pone.0130623. [PMID: 26107947]
  • Helena E Christiansen, Alvine C Mehinto, Fahong Yu, Russell W Perry, Nancy D Denslow, Alec G Maule, Matthew G Mesa. Correlation of gene expression and contaminant concentrations in wild largescale suckers: a field-based study. The Science of the total environment. 2014 Jun; 484(?):379-89. doi: 10.1016/j.scitotenv.2013.08.034. [PMID: 24050789]
  • Katrin Vorkamp, Søren Møller, Knud Falk, Frank F Rigét, Marianne Thomsen, Peter B Sørensen. Levels and trends of toxaphene and chlordane-related pesticides in peregrine falcon eggs from South Greenland. The Science of the total environment. 2014 Jan; 468-469(?):614-21. doi: 10.1016/j.scitotenv.2013.08.073. [PMID: 24056452]
  • Jeffrey M Levengood, David J Soucek, Amy Dickinson, Gregory G Sass, John M Epifanio. Spatial and interspecific patterns in persistent contaminant loads in bighead and silver carp from the Illinois River. Ecotoxicology (London, England). 2013 Sep; 22(7):1174-82. doi: 10.1007/s10646-013-1105-6. [PMID: 23887862]
  • Michio X Watanabe, Tatsuya Kunisue, Norifumi Ueda, Masato Nose, Shinsuke Tanabe, Hisato Iwata. Toxicokinetics of dioxins and other organochlorine compounds in Japanese people: association with hepatic CYP1A2 expression levels. Environment international. 2013 Mar; 53(?):53-61. doi: 10.1016/j.envint.2012.12.008. [PMID: 23333656]
  • Jabir Hussain Syed, Riffat Naseem Malik, Di Liu, Yue Xu, Yan Wang, Jun Li, Gan Zhang, Kevin C Jones. Organochlorine pesticides in air and soil and estimated air-soil exchange in Punjab, Pakistan. The Science of the total environment. 2013 Feb; 444(?):491-7. doi: 10.1016/j.scitotenv.2012.12.018. [PMID: 23295176]
  • Mehmet Isleyen, Pinar Sevim, Joseph Hawthorne, William Berger, Jason C White. Inheritance profile of weathered chlordane and p,p'-DDTs accumulation by Cucurbita pepo hybrids. International journal of phytoremediation. 2013; 15(9):861-76. doi: 10.1080/15226514.2012.760519. [PMID: 23819281]
  • Pilar Suárez, Yolanda Ruiz, Ana Alonso, Fuencisla San Juan. Organochlorine compounds in mussels cultured in the Ría of Vigo: accumulation and origin. Chemosphere. 2013 Jan; 90(1):7-19. doi: 10.1016/j.chemosphere.2012.02.030. [PMID: 22391050]
  • Jessica Lopez, Daryle Boyd, Gina M Ylitalo, Charles Littnan, Ronald Pearce. Persistent organic pollutants in the endangered Hawaiian monk seal (Monachus schauinslandi) from the main Hawaiian Islands. Marine pollution bulletin. 2012 Nov; 64(11):2588-98. doi: 10.1016/j.marpolbul.2012.07.012. [PMID: 22884537]
  • Warren G Foster, Anthony P Cheung, Karelyn Davis, Gillian Graves, John Jarrell, Alain Leblanc, Chun Lei Liang, Tara Leech, Mark Walker, Jean Philippe Weber, Jay Van Oostdam. Circulating metals and persistent organic pollutant concentrations in Canadian and non-Canadian born primiparous women from five Canadian centres: results of a pilot biomonitoring study. The Science of the total environment. 2012 Oct; 435-436(?):326-36. doi: 10.1016/j.scitotenv.2012.06.070. [PMID: 22863808]
  • Ismet Çok, Birgul Mazmanci, Mehmet A Mazmanci, Cafer Turgut, Bernhard Henkelmann, Karl-Werner Schramm. Analysis of human milk to assess exposure to PAHs, PCBs and organochlorine pesticides in the vicinity Mediterranean city Mersin, Turkey. Environment international. 2012 Apr; 40(?):63-69. doi: 10.1016/j.envint.2011.11.012. [PMID: 22280929]
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