Cetiedil (BioDeep_00000009578)
Secondary id: BioDeep_00001871534
human metabolite blood metabolite
代谢物信息卡片
化学式: C20H31NO2S (349.2075)
中文名称: 西替地尔
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: C1CCCN(CC1)CCOC(=O)C(C2CCCCC2)C3=CSC=C3
InChI: InChI=1S/C20H31NO2S/c22-20(23-14-13-21-11-6-1-2-7-12-21)19(18-10-15-24-16-18)17-8-4-3-5-9-17/h10,15-17,19H,1-9,11-14H2
描述信息
C - Cardiovascular system > C04 - Peripheral vasodilators > C04A - Peripheral vasodilators
C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
D006401 - Hematologic Agents > D000986 - Antisickling Agents
ATC code: C04AX26
同义名列表
12 个代谢物同义名
3-Thiopheneacetic acid, alpha-cyclohexyl-, 2-(hexahydro-1H-azepin-1-yl)ethyl ester, hydrochloride (1:1); 2-(Hexahydro-1H-azepin-1-yl)ethyl alpha-cyclohexyl-3-thiopheneacetate citrate (1:1); 2-(azepan-1-yl)ethyl 2-cyclohexyl-2-(thiophen-3-yl)acetate; 2-(azepan-1-yl)ethyl 2-cyclohexyl-2-thiophen-3-ylacetate; 2-(azepan-1-yl)ethyl cyclohexyl(thiophen-3-yl)acetate; Cetiedil hydrochloride; Cetiedil citrate (1:1); Cetiedil citrate; Cetiedil oxalate; Cetiedil; Stratene; Cetiedil
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:34619
- KEGG: C13786
- PubChem: 66384
- HMDB: HMDB0249834
- Metlin: METLIN69705
- DrugBank: DB13753
- ChEMBL: CHEMBL419380
- Wikipedia: Cetiedil
- chemspider: 59759
- CAS: 14176-10-4
- PMhub: MS000023371
- PubChem: 854031
- NIKKAJI: J8.485I
- KNApSAcK: 34619
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- B S Jensen, D Strobaek, P Christophersen, T D Jorgensen, C Hansen, A Silahtaroglu, S P Olesen, P K Ahring. Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel.
The American journal of physiology.
1998 09; 275(3):C848-56. doi:
10.1152/ajpcell.1998.275.3.c848
. [PMID: 9730970] - J Giannettini, M Chauvet, M Dell'Amico, M Bourdeaux. Influence of cetiedil on erythrocyte membrane microviscosity and acetylcholinesterase activity.
Pharmacological research.
1992 Jan; 25(1):31-41. doi:
10.1016/s1043-6618(05)80062-3
. [PMID: 1738756] - M P Dube, F B Davis, P J Davis, S D Blas. Bepridil and cetiedil reversibly inhibit thyroid hormone stimulation in vitro of human red cell Ca2+-ATPase activity.
Molecular endocrinology (Baltimore, Md.).
1987 Feb; 1(2):168-71. doi:
10.1210/mend-1-2-168
. [PMID: 2970587] - C Narasimhan, L W Fung. Molecular properties of cetiedil and its interactions with erythrocyte membranes.
Journal of pharmaceutical sciences.
1986 Jul; 75(7):654-9. doi:
10.1002/jps.2600750707
. [PMID: 3020225] - E P Orringer, J R Powell, R E Cross, J F Rogers, O Wojcieszyn, J C Phillips, J Reed, K T Ng, L R Berkowitz. A single-dose pharmacokinetic study of the antisickling agent cetiedil.
Clinical pharmacology and therapeutics.
1986 Mar; 39(3):276-81. doi:
10.1038/clpt.1986.39
. [PMID: 3512147] - M L Holland, K T Ng. Automated capillary gas chromatographic assay using nitrogen-phosphorus detection for the determination of cetiedil in plasma.
Journal of chromatography.
1985 Nov; 345(1):178-83. doi:
10.1016/0378-4347(85)80151-1
. [PMID: 4086578] - H Kohzaki, K Kakinuma, T Asakura, T Yamakawa. Effects of cetiedil on the oxidative metabolism of activated polymorphonuclear leucocytes.
British journal of haematology.
1985 Jul; 60(3):531-9. doi:
10.1111/j.1365-2141.1985.tb07450.x
. [PMID: 4015989] - J D Henderson, V N Mankad, T M Glenn, Y W Cho. Gas chromatographic analysis of cetiedil, a candidate antisickling agent, in human plasma with nitrogen-sensitive detection.
Journal of pharmaceutical sciences.
1984 Dec; 73(12):1748-51. doi:
10.1002/jps.2600731222
. [PMID: 6527249] - C Larousse, M F Kergueris, Y Le Normand, J Visset. Research on the eventual enzymatic induction activity of cetiedil in rat and man.
International journal of clinical pharmacology, therapy, and toxicology.
1980; 18(5):195-9. doi:
NULL
. [PMID: 7390670]