Benzamil (BioDeep_00000009554)
Secondary id: BioDeep_00001875818
human metabolite blood metabolite
代谢物信息卡片
3,5-diamino-N-(N-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide
化学式: C13H14ClN7O (319.0948)
中文名称: 盐酸苯甲酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)CN=C(N)NC(=O)C2=C(N=C(C(=N2)Cl)N)N
InChI: InChI=1S/C13H14ClN7O/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22)
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:34558
- KEGG: C13751
- PubChem: 108107
- HMDB: HMDB0248972
- Metlin: METLIN69682
- ChEMBL: CHEMBL212579
- Wikipedia: Benzamil
- chemspider: 97202
- CAS: 2898-76-2
- PMhub: MS000023347
- PubChem: 586340
- NIKKAJI: J346.598E
- KNApSAcK: 34558
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Liga Skarda, Julia Kowal, Kaspar P Locher. Structure of the Human Cholesterol Transporter ABCG1.
Journal of molecular biology.
2021 10; 433(21):167218. doi:
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American journal of physiology. Renal physiology.
2021 04; 320(4):F596-F607. doi:
10.1152/ajprenal.00444.2020. [PMID: 33554781] - Niklas Ayasse, Peder Berg, Jens Leipziger, Mads Vaarby Sørensen. ENaC expression correlates with the acute furosemide-induced K+ excretion.
Physiological reports.
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2020 05; 31(5):1009-1023. doi:
10.1681/asn.2019080790. [PMID: 32245797] - Reham H Soliman, Jermaine G Johnston, Eman Y Gohar, Crystal M Taylor, David M Pollock. Greater natriuretic response to ENaC inhibition in male versus female Sprague-Dawley rats.
American journal of physiology. Regulatory, integrative and comparative physiology.
2020 02; 318(2):R418-R427. doi:
10.1152/ajpregu.00060.2019. [PMID: 31913682] - Hong Zheng, Xuefei Liu, Kenichi Katsurada, Kaushik P Patel. Renal denervation improves sodium excretion in rats with chronic heart failure: effects on expression of renal ENaC and AQP2.
American journal of physiology. Heart and circulatory physiology.
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JCI insight.
2019 04; 5(?):. doi:
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Journal of cellular biochemistry.
2019 01; 120(1):461-469. doi:
10.1002/jcb.27402. [PMID: 30203535] - Rikke Ydegaard, Henrik Andersen, Christina S Oxlund, Ib A Jacobsen, Pernille B L Hansen, Jonathan F Jürgensen, Antonio Augusto Peluso, Paul M Vanhoutte, Mette Staehr, Per Svenningsen, Boye L Jensen. The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice.
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American journal of physiology. Renal physiology.
2017 Dec; 313(6):F1209-F1215. doi:
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American journal of physiology. Renal physiology.
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
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American journal of physiology. Renal physiology.
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The Journal of clinical investigation.
2015 May; 125(5):2136-50. doi:
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American journal of physiology. Heart and circulatory physiology.
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Pediatric research.
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Experimental physiology.
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Hypertension (Dallas, Tex. : 1979).
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2013 Apr; 304(7):F883-99. doi:
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2013 Feb; 304(3):F279-88. doi:
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American journal of physiology. Renal physiology.
2012 Jul; 303(1):F45-55. doi:
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Journal of psychiatric research.
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Hypertension (Dallas, Tex. : 1979).
2011 Feb; 57(2):231-7. doi:
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PloS one.
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American journal of physiology. Renal physiology.
2010 Dec; 299(6):F1374-8. doi:
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2010 Nov; 299(5):R1326-32. doi:
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2010 Oct; 56(4):636-42. doi:
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American journal of physiology. Renal physiology.
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American journal of physiology. Renal physiology.
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American journal of physiology. Renal physiology.
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