PHENOL RED (BioDeep_00000009361)
代谢物信息卡片
化学式: C19H14O5S (354.0562)
中文名称: 苯酚红
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)C(OS2(=O)=O)(C3=CC=C(C=C3)O)C4=CC=C(C=C4)O
InChI: InChI=1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
描述信息
V - Various > V04 - Diagnostic agents > V04C - Other diagnostic agents > V04CH - Tests for renal function and ureteral injuries
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D010635 - Phenolphthaleins
D004396 - Coloring Agents
Same as: D01200
同义名列表
3 个代谢物同义名
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:31991
- KEGG: C12600
- KEGGdrug: D70382
- KEGGdrug: D01200
- PubChem: 4766
- Metlin: METLIN69460
- DrugBank: DB13212
- ChEMBL: CHEMBL258921
- MeSH: Phenolsulfonphthalein
- CAS: 143-74-8
- PMhub: MS000023133
- PubChem: 582990
- NIKKAJI: J5.823H
- KNApSAcK: 31991
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yanhong Li, Xinyan Qu, Quanbo Wang, Sheng Li, Qiang Zhang, Xiaomei Zhang. Tannic acid and carboxymethyl chitosan-based multi-functional double-layered hydrogel with pH-stimulated response behavior for smart real-time infection monitoring and wound treatment.
International journal of biological macromolecules.
2023 Dec; 261(Pt 1):129042. doi:
10.1016/j.ijbiomac.2023.129042
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Mikrochimica acta.
2023 01; 190(2):79. doi:
10.1007/s00604-023-05644-y
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2022 Nov; 47(22):6191-6198. doi:
10.19540/j.cnki.cjcmm.20220613.706
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Planta medica.
2022 Oct; 88(13):1223-1232. doi:
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Naunyn-Schmiedeberg's archives of pharmacology.
2022 08; 395(8):963-974. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2022 Jul; 47(14):3898-3907. doi:
10.19540/j.cnki.cjcmm.20220310.401
. [PMID: 35850848] - Yoshinobu Nakamura, Hina Kozakai, Tsubura Nishio, Kazuki Yoshida, Takeo Nakanishi. Phenolsulfonphthalein as a surrogate substrate to assess altered function of the prostaglandin transporter SLCO2A1.
Drug metabolism and pharmacokinetics.
2022 Jun; 44(?):100452. doi:
10.1016/j.dmpk.2022.100452
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ACS applied materials & interfaces.
2021 Oct; 13(40):47354-47370. doi:
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Analytical methods : advancing methods and applications.
2021 01; 13(2):169-178. doi:
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2020 Nov; 219(?):121202. doi:
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2020 09; 69(3):178-185. doi:
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Scientific reports.
2020 03; 10(1):4829. doi:
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Mediators of inflammation.
2020; 2020(?):2929163. doi:
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. [PMID: 32508523] - Sabrein H Mohamed, Yousry M Issa, Shaimaa A Elfeky. Extraction-free spectrophotometric assay of the antitussive drug pentoxyverine citrate using sulfonephthalein dyes.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2019 Nov; 222(?):117186. doi:
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
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Journal of colloid and interface science.
2019 Nov; 555(?):145-156. doi:
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Journal of immunological methods.
2019 08; 471(?):18-26. doi:
10.1016/j.jim.2019.05.003
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Journal of nutritional science and vitaminology.
2019; 65(1):31-37. doi:
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. [PMID: 30814409] - Kayla A Ross, David S Kolb, Alysson Macedo, Marion Anderson, Claudia Klein. Seminal plasma does not aid in the transport of phenolsulfonphthalein across the uterotubal junction in mares.
The Canadian veterinary journal = La revue veterinaire canadienne.
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Bioorganic & medicinal chemistry.
2018 01; 26(1):278-284. doi:
10.1016/j.bmc.2017.11.046
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Biopharmaceutics & drug disposition.
2017 Nov; 38(8):479-485. doi:
10.1002/bdd.2089
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Scandinavian journal of clinical and laboratory investigation.
2017 Sep; 77(5):358-372. doi:
10.1080/00365513.2017.1325927
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The British journal of nutrition.
2017 Apr; 117(8):1086-1094. doi:
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Journal of microbiological methods.
2016 12; 131(?):102-104. doi:
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2016 Oct; 48(4):320-324. doi:
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Pharmaceutical biology.
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Talanta.
2016; 148(?):264-71. doi:
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2015 Oct; 151(?):89-99. doi:
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Fundamental & clinical pharmacology.
2015 Feb; 29(1):86-94. doi:
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. [PMID: 24920467] - Yuichi Uwai, Misato Tsuge, Yuta Tokai, Tatsuya Kawasaki, Tomohiro Nabekura. Lithium Interferes with the Urinary Excretion of Phenolsulfonphthalein in Rats: Involvement of a Reduced Content of α-Ketoglutarate, the Driving Force for Organic Anion Transporters OAT1 and OAT3, in the Kidney Cortex.
Pharmacology.
2015; 96(5-6):278-83. doi:
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2015 Jan; 10(1):136-42. doi:
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Clinical nutrition (Edinburgh, Scotland).
2014 Dec; 33(6):1140-6. doi:
10.1016/j.clnu.2013.12.014
. [PMID: 24461940] - Hiroaki Honjo, Yuichi Uwai, Tomohiro Nabekura. Effect of selective cyclooxygenase-2 inhibitor lumiracoxib on phenolsulfonphthalein disposition in rats.
Drug metabolism and drug interactions.
2014; 29(3):203-6. doi:
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. [PMID: 24870608] - Yong-Jun Shin, Joo Hyun Lee, Ju-Hee Oh, Young-Joo Lee. Low-dose probenecid selectively inhibits urinary excretion of phenolsulfonphthalein in rats without affecting biliary excretion.
Journal of applied toxicology : JAT.
2013 Jun; 33(6):511-5. doi:
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Ultrasonics sonochemistry.
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International journal of molecular sciences.
2012 Sep; 13(10):12336-48. doi:
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Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences.
2012 07; 41(4):430-3, 449. doi:
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American journal of physiology. Renal physiology.
2012 Jun; 302(12):F1640-9. doi:
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2012 Jun; 31(6):1093-103. doi:
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Journal of ethnopharmacology.
2012 Mar; 140(1):83-90. doi:
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Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva.
2012 Feb; 104(1):4-9. doi:
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2012 Jan; 139(1):189-93. doi:
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Analytical biochemistry.
2011 Sep; 416(1):92-9. doi:
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Plant & cell physiology.
2011 Aug; 52(8):1274-88. doi:
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Toxicology and industrial health.
2011 May; 27(4):379-84. doi:
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Mediators of inflammation.
2011; 2011(?):152137. doi:
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2010 Dec; 33(12):2025-31. doi:
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Molecular endocrinology (Baltimore, Md.).
2009 Jun; 23(6):784-93. doi:
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Journal of medicinal food.
2009 Feb; 12(1):37-46. doi:
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Journal of natural medicines.
2008 Oct; 62(4):396-402. doi:
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Artificial organs.
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2008 Aug; 24(8):1061-4. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2008 Aug; 33(15):1890-4. doi:
"
. [PMID: 19007024] - Shirou Itagaki, Makoto Chiba, Masaki Kobayashi, Mitsuru Sugawara, Michiya Kobayashi, Takeshi Hirano, Ken Iseki. Functional analysis of phenolsulfonphthalein transport system in Long-Evans Cinnamon rats.
Biochimica et biophysica acta.
2008 Jan; 1778(1):270-5. doi:
10.1016/j.bbamem.2007.09.025
. [PMID: 17976528] - Shintaro Fumoto, Yukiko Nakashima, Koyo Nishida, Yukinobu Kodama, Junya Nishi, Mikiro Nakashima, Hitoshi Sasaki, Noboru Otsuka, Junzo Nakamura. Evaluation of enhanced peritoneum permeability in methylglyoxal-treated rats as a diagnostic method for peritoneal damage.
Pharmaceutical research.
2007 Oct; 24(10):1891-6. doi:
10.1007/s11095-007-9313-5
. [PMID: 17476464] - Koyo Nishida, Madoka Okazaki, Ryuichi Sakamoto, Natsuko Inaoka, Hideaki Miyake, Shintaro Fumoto, Junzo Nakamura, Mikiro Nakashima, Hitoshi Sasaki, Mikio Kakumoto, Toshiyuki Sakaeda. Change in pharmacokinetics of model compounds with different elimination processes in rats during hypothermia.
Biological & pharmaceutical bulletin.
2007 Sep; 30(9):1763-7. doi:
10.1248/bpb.30.1763
. [PMID: 17827736] - Mukesh Jain, Kudithipudi Chengalrayan, Ahmed Abouzid, Maria Gallo. Prospecting the utility of a PMI/mannose selection system for the recovery of transgenic sugarcane (Saccharum spp. hybrid) plants.
Plant cell reports.
2007 May; 26(5):581-90. doi:
10.1007/s00299-006-0244-0
. [PMID: 17149641] - Kim Leblanc, Emilie Sexton, Sophie Parent, Geoffroy Bélanger, Marie-Claude Déry, Virginie Boucher, Eric Asselin. Effects of 4-hydroxytamoxifen, raloxifene and ICI 182 780 on survival of uterine cancer cell lines in the presence and absence of exogenous estrogens.
International journal of oncology.
2007 Feb; 30(2):477-87. doi:
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- Sonia, Raman Saini, Rana P Singh, Pawan K Jaiwal. Agrobacterium tumefaciens mediated transfer of Phaseolus vulgaris alpha-amylase inhibitor-1 gene into mungbean Vigna radiata (L.) Wilczek using bar as selectable marker.
Plant cell reports.
2007 Feb; 26(2):187-98. doi:
10.1007/s00299-006-0224-4
. [PMID: 16983450] - Subhankar Roy-Barman, Christof Sautter, Bharat B Chattoo. Expression of the lipid transfer protein Ace-AMP1 in transgenic wheat enhances antifungal activity and defense responses.
Transgenic research.
2006 Aug; 15(4):435-46. doi:
10.1007/s11248-006-0016-1
. [PMID: 16906444] - G E Granero, C Ramachandran, G L Amidon. Rapid in vivo dissolution of ketoprofen: implications on the biopharmaceutics classification system.
Die Pharmazie.
2006 Aug; 61(8):673-6. doi:
NULL
. [PMID: 16964708] - C Dawes. Absorption of urea through the oral mucosa and estimation of the percentage of secreted whole saliva inadvertently swallowed during saliva collection.
Archives of oral biology.
2006 Feb; 51(2):111-6. doi:
10.1016/j.archoralbio.2005.05.007
. [PMID: 16023991] - Sarah L Tao, Tejal A Desai. Micromachined devices: the impact of controlled geometry from cell-targeting to bioavailability.
Journal of controlled release : official journal of the Controlled Release Society.
2005 Dec; 109(1-3):127-38. doi:
10.1016/j.jconrel.2005.09.019
. [PMID: 16274828] - M Broccardo, S Scaccianoce, P Del Bianco, S Agostini, C Petrella, G Improta. Nociceptin/orphanin FQ-induced delay in gastric emptying: role of central corticotropin-releasing factor and glucocorticoid receptors.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
2005 Dec; 17(6):871-7. doi:
10.1111/j.1365-2982.2005.00717.x
. [PMID: 16336503] - Shirou Itagaki, Soji Shimamoto, Mitsuru Sugawara, Michiya Kobayashi, Katsumi Miyazaki, Takeshi Hirano, Ken Iseki. Phenolsulfonphthalein transport by potential-sensitive urate transport system.
European journal of pharmacology.
2005 Aug; 518(2-3):83-9. doi:
10.1016/j.ejphar.2005.06.009
. [PMID: 16083873] - Koyo Nishida, Akiko Kuma, Shintaro Fumoto, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura. Absorption characteristics of model compounds from the small intestinal serosal surface and a comparison with other organ surfaces.
The Journal of pharmacy and pharmacology.
2005 Aug; 57(8):1073-7. doi:
10.1211/0022357056677
. [PMID: 16102265] - Timothy W Meyer, Jason L Walther, Maria Enrica Pagtalunan, Andres W Martinez, Ali Torkamani, Patrick D Fong, Natalie S Recht, Channing R Robertson, Thomas H Hostetter. The clearance of protein-bound solutes by hemofiltration and hemodiafiltration.
Kidney international.
2005 Aug; 68(2):867-77. doi:
10.1111/j.1523-1755.2005.00469.x
. [PMID: 16014068] - Koyo Nishida, Manabu Kamenosono, Akiko Kuma, Shintaro Fumoto, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura. Delivery advantage to the unilateral kidney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model.
Journal of drug targeting.
2005 May; 13(4):215-23. doi:
10.1080/10611860500159097
. [PMID: 16051533] - Gareth C Davies, M Julie Thornton, Tracey J Jenner, Yi-Ju Chen, John B Hansen, Richard D Carr, Valerie A Randall. Novel and established potassium channel openers stimulate hair growth in vitro: implications for their modes of action in hair follicles.
The Journal of investigative dermatology.
2005 Apr; 124(4):686-94. doi:
10.1111/j.0022-202x.2005.23643.x
. [PMID: 15816824] - Weidong Xie, Dongming Xing, Yunan Zhao, Hui Su, Zhen Meng, Yunyun Chen, Lijun Du. A new tactic to treat postprandial hyperlipidemia in diabetic rats with gastroparesis by improving gastrointestinal transit.
European journal of pharmacology.
2005 Mar; 510(1-2):113-20. doi:
10.1016/j.ejphar.2005.01.019
. [PMID: 15740731] - Mari Takahashi, Hiraku Onishi, Yoshiharu Machida. Development of implant tablet for a week-long sustained release.
Journal of controlled release : official journal of the Controlled Release Society.
2004 Nov; 100(1):63-74. doi:
10.1016/j.jconrel.2004.07.031
. [PMID: 15491811] - Ji Yong Ann, Sang Jung Kim, Sang Pyo Han, Jeong Wook Kim, Hyung Joon Kim, Jae Hyuk Do, Jae Gyu Kim, Sae Kyung Chang, Woo Kyu Jeon. [Effect of glutamine on the non-steroidal anti-inflammatory drug-induced bacterial translocation].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi.
2004 Nov; 44(5):252-8. doi:
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- Koyo Nishida, Naoki Tomiyama, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura. Absorption characteristics of compounds with different molecular weights after application to the unilateral kidney surface in rats.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2004 Nov; 58(3):705-11. doi:
10.1016/j.ejpb.2004.04.016
. [PMID: 15451548] - Anna Gerenday, Ann M Fallon. Ecdysone-induced accumulation of mosquito cells in the G1 phase of the cell cycle.
Journal of insect physiology.
2004 Sep; 50(9):831-8. doi:
10.1016/j.jinsphys.2004.06.005
. [PMID: 15350503] - Shirou Itagaki, Soji Shimamoto, Takeshi Hirano, Ken Iseki, Mitsuru Sugawara, Sachiho Nishimura, Michio Fujimoto, Michiya Kobayashi, Katsumi Miyazaki. Comparison of urinary excretion of phenolsulfonphthalein in an animal model for Wilson's disease (Long-Evans Cinnamon rats) with that in normal Wistar rats: involvement of primary active organic anion transporter.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2004 Jul; 7(2):227-34. doi:
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- Timothy W Meyer, Evonne C Leeper, Derek W Bartlett, Thomas A Depner, Yiming Zhao Lit, Channing R Robertson, Thomas H Hostetter. Increasing dialysate flow and dialyzer mass transfer area coefficient to increase the clearance of protein-bound solutes.
Journal of the American Society of Nephrology : JASN.
2004 Jul; 15(7):1927-35. doi:
10.1097/01.asn.0000131521.62256.f0
. [PMID: 15213283] - Koyo Nishida, Seiichi Nose, Akiko Kuma, Takahiro Mukai, Mikiro Nakashima, Hitoshi Sasaki, Junzo Nakamura. Absorption of phenolsulfonphthalein as a model across the mesenteric surface in rats to determine the drug absorption route after intraperitoneal administration.
The Journal of pharmacy and pharmacology.
2004 May; 56(5):683-7. doi:
10.1211/0022357023385
. [PMID: 15142348] - Hai-Xia Ming, Jia-Jun Liu, Shi-Zuo Huang. [Influence of single leaf Asarum himalaicum on renal function of rabbits].
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2004 May; 2(3):199-202. doi:
10.3736/jcim20040314
. [PMID: 15339444] - A H Sawas, S N Pentyala. Evaluation of lipid peroxidation in red blood cells by monitoring the uptake of sucrose and phenol red.
Journal of applied toxicology : JAT.
2004 May; 24(3):223-9. doi:
10.1002/jat.976
. [PMID: 15211617] - Shirou Itagaki, Mitsuru Sugawara, Michiya Kobayashi, Katsumi Miyazaki, Takeshi Hirano, Ken Iseki. Comparison of the disposition behavior of organic anions in an animal model for Wilson's disease (Long-Evans Cinnamon rats) with that in normal Long-Evans Agouti rats.
Drug metabolism and pharmacokinetics.
2004 Apr; 19(2):150-4. doi:
10.2133/dmpk.19.150
. [PMID: 15499181] - Ewa Iwaszko, Anna Wardak, Zbigniew Krupa, Wiesław I Gruszecki. Ion transport across model lipid membranes containing light-harvesting complex II: an effect of light.
Journal of photochemistry and photobiology. B, Biology.
2004 Mar; 74(1):13-21. doi:
10.1016/j.jphotobiol.2004.01.005
. [PMID: 15043842] - Yuji Sakurai, Hideyuki Motohashi, Harumasa Ueo, Satohiro Masuda, Hideyuki Saito, Masahiro Okuda, Noriko Mori, Motokazu Matsuura, Toshio Doi, Atsushi Fukatsu, Osamu Ogawa, Ken-ichi Inui. Expression levels of renal organic anion transporters (OATs) and their correlation with anionic drug excretion in patients with renal diseases.
Pharmaceutical research.
2004 Jan; 21(1):61-7. doi:
10.1023/b:pham.0000012153.71993.cb
. [PMID: 14984259] - Shirou Itagaki, Mitsuru Sugawara, Michiya Kobayashi, Sachiho Nishimura, Michio Fujimoto, Katsumi Miyazaki, Ken Iseki. Major role of organic anion transporters in the uptake of phenolsulfonphthalein in the kidney.
European journal of pharmacology.
2003 Aug; 475(1-3):85-92. doi:
10.1016/s0014-2999(03)02111-3
. [PMID: 12954363] - Somchai Luangjaru, Kait Ruxrungtham, Narumon Wisedopas, Varocha Mahachai. D-xylose absorption in non-chronic diarrhea AIDS patients with the wasting syndrome.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet.
2003 Jun; 86 Suppl 2(?):S477-83. doi:
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- Bao-sheng Liu, Hong-yi Zhang, Fu-li Wang. [The reactions between acidic phenolsulfonphthaleins and human serum albumin].
Guang pu xue yu guang pu fen xi = Guang pu.
2003 Jun; 23(3):539-42. doi:
NULL
. [PMID: 12953536] - Bao-sheng Liu, Hong-yi Zhang, Hong-lei Zhang, Yong Zhao. [The high-sensitivity determination of protein concentration by the enhancement of resonance light scattering of chlorophenol red].
Guang pu xue yu guang pu fen xi = Guang pu.
2003 Apr; 23(2):229-31. doi:
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. [PMID: 12961856] - Shirou Itagaki, Mitsuru Sugawara, Michiya Kobayashi, Katsumi Miyazaki, Ken Iseki. Mechanism of active secretion of phenolsulfonphthalein in the liver via Mrp2 (abcc2), an organic anion transporter.
Drug metabolism and pharmacokinetics.
2003; 18(4):238-44. doi:
10.2133/dmpk.18.238
. [PMID: 15618741] - Stephen J Hernandez-Divers. Green iguana nephrology: a review of diagnostic techniques.
The veterinary clinics of North America. Exotic animal practice.
2003 Jan; 6(1):233-50. doi:
10.1016/s1094-9194(02)00025-7
. [PMID: 12616842] - Pamela L Drake, Edward Krieg, Alexander W Teass, Val Vallyathan. Two assays for urinary N-acetyl-beta-D-glucosaminidase compared.
Clinical chemistry.
2002 Sep; 48(9):1604-5. doi:
10.1093/clinchem/48.9.1604
. [PMID: 12194947] - Koyo Nishida, Seiichi Nose, Akiko Kuma, Takahiro Mukai, Shigeru Kawakami, Mikiro Nakashima, Hitoshi Sasaki, Toshiyuki Sakaeda, Junzo Nakamura. Absorption characteristics of model compounds with different molecular weights from the serosal caecal surface in rats.
The Journal of pharmacy and pharmacology.
2002 Jul; 54(7):1005-9. doi:
10.1211/002235702760089144
. [PMID: 12162704] - Antony S Jeevarajan, Sundeep Vani, Thomas D Taylor, Melody M Anderson. Continuous pH monitoring in a perfused bioreactor system using an optical pH sensor.
Biotechnology and bioengineering.
2002 May; 78(4):467-72. doi:
10.1002/bit.10212
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