Floridin (BioDeep_00000008850)

 

Secondary id: BioDeep_00000858472

human metabolite


代谢物信息卡片


1-{[(6R,7R)-2-carboxylato-7-{[1-hydroxy-2-(thiophen-2-yl)ethylidene]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium

化学式: C19H17N3O4S2 (415.066)
中文名称: 头孢噻啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(=C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=CC=C4
InChI: InChI=1S/C19H17N3O4S2/c23-14(9-13-5-4-8-27-13)20-15-17(24)22-16(19(25)26)12(11-28-18(15)22)10-21-6-2-1-3-7-21/h1-8,15,18H,9-11H2,(H-,20,23,25,26)/t15-,18-/m1/s1

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DB - First-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
It is used in food processing as a filtration agent and flocculating agent
Same as: D01075

同义名列表

30 个代谢物同义名

1-{[(6R,7R)-2-carboxylato-7-{[1-hydroxy-2-(thiophen-2-yl)ethylidene]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium; (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; (6R,7R)-8-oxo-3-(Pyridinium-1-ylmethyl)-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-8-oxo-3-(Pyridinium-1-ylmethyl)-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; N-(7-((2-Thienyl)acetamido)ceph-3-em-3-ylmethyl)pyridinium-4-carboxylic acid; N-(7-((2-Thienyl)acetamido)ceph-3-em-3-ylmethyl)pyridinium-4-carboxylate; N-(7-(2-Thienylacetamidoceph-3-ylmethyl))-pyridinium-2-carboxylic acid; N-(7-(2-Thienylacetamidoceph-3-ylmethyl))-pyridinium-2-carboxylate; 7-((2-Thienyl)acetamido)-3-(1-pyridylmethyl)cephalosporanic acid; 7-((2-Thienyl)acetamido)-3-(1-pyridylmethyl)cephalosporanate; NCGC00094956-01; Cephaloridinum; cephaloridine; Cephalomycine; Cefaloridinum; Cefaloridina; Cephaloridin; cefaloridine; Cefalorizin; Cepaloridin; Cefaloridin; Kefloridin; Cepalorin; Ceflorin; deflorin; Floridin; Ceporin; Cer; Cephaloridine; Cephaloridine



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ABCB1, ALB, CAT, EIF2AK3, GLUL, HPGDS, SLC22A5
Endoplasmic reticulum membrane 3 EIF2AK3, HSP90B1, OSTC
Nucleus 5 ALB, EIF2AK3, GLUL, HSP90B1, OMP
cytosol 9 ALB, CAT, EIF2AK3, GLUL, GSR, HPGDS, HSP90B1, OMP, SLC22A5
centrosome 1 ALB
nucleoplasm 1 HPGDS
Cell membrane 5 ABCB1, GLUL, HAVCR1, SLC15A2, SLC22A5
Lipid-anchor 1 GLUL
Multi-pass membrane protein 8 ABCB1, ABCC3, OSTC, SLC15A2, SLC22A5, SLC22A6, SLC22A8, SLC22A9
Synapse 1 OMP
cell surface 2 ABCB1, HAVCR1
Golgi apparatus 1 ALB
mitochondrial inner membrane 1 FECH
neuronal cell body 1 OMP
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 GLUL
plasma membrane 9 ABCB1, ABCC3, GLUL, HAVCR1, IGHE, SLC15A2, SLC22A5, SLC22A6, SLC22A8
Membrane 9 ABCB1, ABCC3, CAT, EIF2AK3, HSP90B1, OSTC, SLC15A2, SLC22A5, SLC22A6
apical plasma membrane 4 ABCB1, SLC15A2, SLC22A5, SLC22A8
axon 1 OMP
basolateral plasma membrane 4 ABCC3, SLC22A6, SLC22A8, SLC22A9
caveola 1 SLC22A6
extracellular exosome 11 ABCB1, ALB, CAT, GLUL, GSR, HSP90B1, LYZ, SLC15A2, SLC22A5, SLC22A6, SLC22A8
endoplasmic reticulum 6 ALB, EIF2AK3, GLUL, HSP90B1, OSTC, SLC22A5
extracellular space 3 ALB, IGHE, LYZ
perinuclear region of cytoplasm 2 EIF2AK3, HSP90B1
mitochondrion 4 CAT, FECH, GLUL, GSR
protein-containing complex 4 ALB, CAT, HSP90B1, SLC22A6
intracellular membrane-bounded organelle 2 CAT, HPGDS
Single-pass type I membrane protein 3 EIF2AK3, HAVCR1, IGHE
Secreted 1 ALB
extracellular region 5 ALB, CAT, HSP90B1, IGHE, LYZ
mitochondrial matrix 3 CAT, FECH, GSR
anchoring junction 1 ALB
motile cilium 1 HAVCR1
external side of plasma membrane 1 GSR
midbody 1 HSP90B1
Apical cell membrane 3 ABCB1, SLC15A2, SLC22A5
Mitochondrion inner membrane 1 FECH
focal adhesion 2 CAT, HSP90B1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 HSP90B1
lateral plasma membrane 1 SLC22A8
ciliary basal body 1 ALB
IgE immunoglobulin complex 1 IGHE
Cytoplasmic vesicle, phagosome membrane 1 SLC15A2
phagocytic vesicle membrane 1 SLC15A2
centriole 1 ALB
brush border membrane 1 SLC22A5
spindle pole 1 ALB
blood microparticle 1 ALB
Basolateral cell membrane 4 ABCC3, SLC22A6, SLC22A8, SLC22A9
[Isoform 2]: Cell membrane 1 IGHE
Melanosome 1 HSP90B1
cell body 1 GLUL
sperm plasma membrane 1 HSP90B1
basal plasma membrane 3 ABCC3, SLC22A5, SLC22A6
Microsome 1 GLUL
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 ALB, HSP90B1
platelet alpha granule lumen 1 ALB
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
azurophil granule lumen 1 LYZ
Sarcoplasmic reticulum lumen 1 HSP90B1
Basal cell membrane 3 ABCC3, SLC22A5, SLC22A6
external side of apical plasma membrane 1 ABCB1
[Isoform 3]: Endoplasmic reticulum 1 SLC22A5
[Isoform 3]: Cell membrane 1 IGHE
glial cell projection 1 GLUL
endocytic vesicle lumen 1 HSP90B1
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
catalase complex 1 CAT
oligosaccharyltransferase complex 1 OSTC
endoplasmic reticulum chaperone complex 1 HSP90B1
ciliary transition fiber 1 ALB


文献列表

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  • Kazuharu Ienaga, Chan Hum Park, Takako Yokozawa. Protective effect of an intrinsic antioxidant, HMH (5-hydroxy-1-methylhydantoin; NZ-419), against cellular damage of kidney tubules. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 2013 Jul; 65(5):559-66. doi: 10.1016/j.etp.2012.05.001. [PMID: 22749566]
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