WLN: RVR (BioDeep_00000870837)
Main id: BioDeep_00000001854
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C13H10O (182.0732)
中文名称: 二苯甲酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC=C2
InChI: InChI=1S/C13H10O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H
描述信息
D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents
D003879 - Dermatologic Agents
Benzophenone is an endogenous metabolite.
Benzophenone is an endogenous metabolite.
同义名列表
49 个代谢物同义名
InChI=1\C13H10O\c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12\h1-10; Mettler Toledo Calibration substance ME 18870, Benzophenone; EPA Pesticide Chemical Code 000315; BENZOPHENONE (DIPHENYL-KETONE); .alpha.-Oxodiphenylmethane; METHANONE, diphenyl- (9ci); alpha-Oxodiphenylmethane; Methanone, diphenyl-; Di(phenyl)methanone; BENZOPHENONE (8ci); DIPHENYLMETHANONE; Benzene, benzoyl-; .alpha.-Oxoditane; EINECS 204-337-6; UPCMLD-DP071:001; Ketone, diphenyl; Caswell No. 081G; alpha-Oxoditane; W213403_ALDRICH; NCGC00090787-03; NCGC00090787-04; NCGC00090787-01; Diphenyl ketone; Diphenylketone; 442842_SUPELCO; 427551_ALDRICH; Benzoylbenzene; Phenyl ketone; FEMA No. 2134; ZINC00968233; BENZOPHENONE; 73664_FLUKA; CHEBI:41308; 239852_SIAL; AIDS-017932; B9300_SIAL; AIDS017932; HSDB 6809; AI3-00754; CCRIS 629; ST5214455; NSC 8077; WLN: RVR; 119-61-9; NSC8077; C06354; BZQ; Benzophenone; Benzophenone
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:41308
- KEGG: C06354
- PubChem: 3102
- DrugBank: DB01878
- ChEMBL: CHEMBL90039
- CAS: 119-61-9
- PubChem: 8590
- PDB-CCD: BZQ
- NIKKAJI: J2.481C
- medchemexpress: HY-Y0546
- KNApSAcK: 41308
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
7 个相关的物种来源信息
- 4039 - Daucus carota: 10.1002/CBDV.201300390
- 4463 - Sauromatum venosum: 10.1016/S0031-9422(00)94756-3
- 1883 - Streptomyces:
- 933385 - Tripterospermum taiwanense: -
- 33090 - 木蝴蝶: -
- 33090 - 辛夷: -
- 33090 - 黄芩: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Qi Chen, Qianyu Chen, Guanyong Su, Da Chen, Zhen Ding, Hong Sun. The associations between high-levels of urine benzophenone-type UV filters (BPs) and changes in serum lipid concentrations.
Chemosphere.
2023 Oct; 346(?):140545. doi:
10.1016/j.chemosphere.2023.140545
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Toxicology mechanisms and methods.
2023 Jul; ?(?):1-11. doi:
10.1080/15376516.2023.2223291
. [PMID: 37434431] - Jiayin Long, Qingqing Mao, Yujie Peng, Lei Liu, Yin Hong, Honglin Xiang, Ming Ma, Hui Zou, Junwei Kuang. Three New Benzophenone Derivatives from Selaginella tamariscina.
Molecules (Basel, Switzerland).
2023 Jun; 28(12):. doi:
10.3390/molecules28124582
. [PMID: 37375139] - Ge Zou, Taobo Li, Wencong Yang, Bing Sun, Yan Chen, Bo Wang, Yanghui Ou, Huijuan Yu, Zhigang She. Antioxidative Indenone and Benzophenone Derivatives from the Mangrove-Derived Fungus Cytospora heveae NSHSJ-2.
Marine drugs.
2023 Mar; 21(3):. doi:
10.3390/md21030181
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Toxicology and applied pharmacology.
2022 11; 455(?):116264. doi:
10.1016/j.taap.2022.116264
. [PMID: 36208703] - Sai Hung Lau, I-Chen Lin, Ching-Lun Su, Yi-Tang Chang, Wann-Neng Jane. Synthesis of cross-linked magnetic chitosan beads immobilised with bacteria for aerobic biodegrading benzophenone-type UV filter.
Chemosphere.
2022 Nov; 307(Pt 3):136010. doi:
10.1016/j.chemosphere.2022.136010
. [PMID: 35973493] - Agnieszka Wnuk, Małgorzata Kajta. Is the commonly used UV filter benzophenone-3 a risk factor for the nervous system?.
Acta biochimica Polonica.
2021 Aug; 68(4):557-563. doi:
10.18388/abp.2020_5741
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Aquatic toxicology (Amsterdam, Netherlands).
2021 Jun; 235(?):105835. doi:
10.1016/j.aquatox.2021.105835
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Cell reports.
2021 04; 35(4):109040. doi:
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Transfusion.
2021 02; 61(2):594-602. doi:
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Drug design, development and therapy.
2021; 15(?):3523-3533. doi:
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Molecules (Basel, Switzerland).
2020 Dec; 25(23):. doi:
10.3390/molecules25235690
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Molecules (Basel, Switzerland).
2020 Nov; 25(21):. doi:
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Analytical chemistry.
2020 10; 92(20):14130-14138. doi:
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Food & function.
2020 Sep; 11(9):8297-8308. doi:
10.1039/d0fo01338b
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Chemosphere.
2020 May; 247(?):125887. doi:
10.1016/j.chemosphere.2020.125887
. [PMID: 31978656] - Anna Dalinova, Leonid Chisty, Dmitry Kochura, Varvara Garnyuk, Maria Petrova, Darya Prokofieva, Anton Yurchenko, Vsevolod Dubovik, Alexander Ivanov, Sergey Smirnov, Andrey Zolotarev, Alexander Berestetskiy. Isolation and Bioactivity of Secondary Metabolites from Solid Culture of the Fungus, Alternaria sonchi.
Biomolecules.
2020 01; 10(1):. doi:
10.3390/biom10010081
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Bioorganic chemistry.
2019 11; 92(?):103220. doi:
10.1016/j.bioorg.2019.103220
. [PMID: 31493708] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - Neil Miller, Stephanie C Bosman, Christiaan J Malherbe, Dalene De Beer, Elizabeth Joubert. Membrane selection and optimisation of tangential flow ultrafiltration of Cyclopia genistoides extract for benzophenone and xanthone enrichment.
Food chemistry.
2019 Sep; 292(?):121-128. doi:
10.1016/j.foodchem.2019.04.047
. [PMID: 31054655] - Huibo Liu, Yuchan Chen, Haohua Li, Saini Li, Haibo Tan, Zhaoming Liu, Dongli Li, Hongxin Liu, Weimin Zhang. Four new metabolites from the endophytic fungus Diaporthe lithocarpus A740.
Fitoterapia.
2019 Sep; 137(?):104260. doi:
10.1016/j.fitote.2019.104260
. [PMID: 31284016] - Leïla Bechtella, Carla Kirschbaum, Marine Cosset, Gilles Clodic, Lucrèce Matheron, Gérard Bolbach, Sandrine Sagan, Astrid Walrant, Emmanuelle Sachon. Benzophenone Photoreactivity in a Lipid Bilayer To Probe Peptide/Membrane Interactions: Simple System, Complex Information.
Analytical chemistry.
2019 07; 91(14):9102-9110. doi:
10.1021/acs.analchem.9b01584
. [PMID: 31251038] - Tatsuru Hayashi, Hiroshi Tsuchikawa, Yuichi Umegawa, Michio Murata. Small structural alterations greatly influence the membrane affinity of lipophilic ligands: Membrane interactions of bafilomycin A1 and its desmethyl derivative bearing 19F-labeling.
Bioorganic & medicinal chemistry.
2019 04; 27(8):1677-1682. doi:
10.1016/j.bmc.2019.03.017
. [PMID: 30878192] - Hongxiu Liu, Jiufeng Li, Wei Xia, Bin Zhang, Yang Peng, Yuanyuan Li, Yanqiu Zhou, Jing Fang, Hongzhi Zhao, Yangqian Jiang, Wenyu Liu, Xiaojie Sun, Cheng Hu, Zongwei Cai, Shunqing Xu. Blood pressure changes during pregnancy in relation to urinary paraben, triclosan and benzophenone concentrations: A repeated measures study.
Environment international.
2019 01; 122(?):185-192. doi:
10.1016/j.envint.2018.11.003
. [PMID: 30503318] - Tengfei Xu, Zifeng Pi, Fengrui Song, Shu Liu, Zhiqiang Liu. Benzophenone used as the photochemical reagent for pinpointing C=C locations in unsaturated lipids through shotgun and liquid chromatography-mass spectrometry approaches.
Analytica chimica acta.
2018 Oct; 1028(?):32-44. doi:
10.1016/j.aca.2018.04.046
. [PMID: 29884351] - Luigi Lopardo, David Adams, Andrew Cummins, Barbara Kasprzyk-Hordern. Verifying community-wide exposure to endocrine disruptors in personal care products - In quest for metabolic biomarkers of exposure via in vitro studies and wastewater-based epidemiology.
Water research.
2018 10; 143(?):117-126. doi:
10.1016/j.watres.2018.06.028
. [PMID: 29940357] - Danka Bukvički, Miroslav Novaković, Nurunajah Ab Ghani, Petar D Marin, Yoshinori Asakawa. Secondary metabolites from endemic species Iris adriatica Trinajstić ex Mitić (Iridaceae).
Natural product research.
2018 Aug; 32(15):1849-1852. doi:
10.1080/14786419.2017.1402309
. [PMID: 29126369] - Wongvarit Panidthananon, Tanawat Chaowasku, Boonchoo Sritularak, Kittisak Likhitwitayawuid. A New Benzophenone C-Glucoside and Other Constituents of Pseuduvaria fragrans and Their α-Glucosidase Inhibitory Activity.
Molecules (Basel, Switzerland).
2018 Jul; 23(7):. doi:
10.3390/molecules23071600
. [PMID: 30004411] - Evdochia Adoamnei, Jaime Mendiola, Miriam Moñino-García, Fernando Vela-Soria, Luz M Iribarne-Durán, Mariana F Fernández, Nicolás Olea, Niels Jørgensen, Shanna H Swan, Alberto M Torres-Cantero. Urinary concentrations of benzophenone-type ultra violet light filters and reproductive parameters in young men.
International journal of hygiene and environmental health.
2018 04; 221(3):531-540. doi:
10.1016/j.ijheh.2018.02.002
. [PMID: 29449081] - Kazumi Sugihara. [Effect of Environmental Factors on the Ecotoxicity of Pharmaceuticals and Personal Care Products].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2018; 138(3):277-280. doi:
10.1248/yakushi.17-00177-2
. [PMID: 29503416] - Yan-Jun Wan, Li-Xi Liao, Yu-Qi Liu, Yong Jiang, Lian-Ying Liu, Ke-Wu Zeng, Peng-Fei Tu. [Identification and function analysis of target group for cardioprotection of Baoyuan decoction].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2017 Oct; 42(19):3650-3655. doi:
10.19540/j.cnki.cjcmm.2017.0142
. [PMID: 29235274] - G Archana, Rita Dhodapkar, Anupama Kumar. Ecotoxicological risk assessment and seasonal variation of some pharmaceuticals and personal care products in the sewage treatment plant and surface water bodies (lakes).
Environmental monitoring and assessment.
2017 Aug; 189(9):446. doi:
10.1007/s10661-017-6148-3
. [PMID: 28799017] - Izabella Henc, Adam Kokotkiewicz, Piotr Łuczkiewicz, Ewa Bryl, Maria Łuczkiewicz, Jacek M Witkowski. Naturally occurring xanthone and benzophenone derivatives exert significant anti-proliferative and proapoptotic effects in vitro on synovial fibroblasts and macrophages from rheumatoid arthritis patients.
International immunopharmacology.
2017 Aug; 49(?):148-154. doi:
10.1016/j.intimp.2017.05.034
. [PMID: 28587985] - Hongju Liu, Senhua Chen, Weiyang Liu, Yayue Liu, Xishan Huang, Zhigang She. Polyketides with Immunosuppressive Activities from Mangrove Endophytic Fungus Penicillium sp. ZJ-SY₂.
Marine drugs.
2016 Nov; 14(12):. doi:
10.3390/md14120217
. [PMID: 27897975] - Liping Wang, Rong Wu, Wenwei Fu, Yuanzhi Lao, Changwu Zheng, Hongsheng Tan, Hongxi Xu. Synthesis and biological evaluation of Oblongifolin C derivatives as c-Met inhibitors.
Bioorganic & medicinal chemistry.
2016 09; 24(18):4120-4128. doi:
10.1016/j.bmc.2016.06.054
. [PMID: 27396929] - Bokyung Kim, Bareum Kwon, Sol Jang, Pan-Gyi Kim, Kyunghee Ji. Major benzophenone concentrations and influence of food consumption among the general population in Korea, and the association with oxidative stress biomarker.
The Science of the total environment.
2016 Sep; 565(?):649-655. doi:
10.1016/j.scitotenv.2016.05.009
. [PMID: 27208722] - Zolfaghar Aladaghlo, Alireza Fakhari, Mohammad Behbahani. Solvent-assisted dispersive solid-phase extraction: A sample preparation method for trace detection of diazinon in urine and environmental water samples.
Journal of chromatography. A.
2016 Sep; 1462(?):27-34. doi:
10.1016/j.chroma.2016.07.084
. [PMID: 27495366] - G Archana, Rita Dhodapkar, Anupama Kumar. Offline solid-phase extraction for preconcentration of pharmaceuticals and personal care products in environmental water and their simultaneous determination using the reversed phase high-performance liquid chromatography method.
Environmental monitoring and assessment.
2016 Sep; 188(9):512. doi:
10.1007/s10661-016-5510-1
. [PMID: 27502523] - Ahra Ko, Hui-Seung Kang, Jae-Hong Park, Ji-Eun Kwon, Gui Im Moon, Myung-Sil Hwang, In Gyun Hwang. The Association Between Urinary Benzophenone Concentrations and Personal Care Product Use in Korean Adults.
Archives of environmental contamination and toxicology.
2016 May; 70(4):640-6. doi:
10.1007/s00244-015-0240-x
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Molecules (Basel, Switzerland).
2016 Feb; 21(2):251. doi:
10.3390/molecules21020251
. [PMID: 26907243] - Saroj Kumar Amar, Shruti Goyal, Divya Dubey, Ajeet K Srivastav, Deepti Chopra, Jyoti Singh, Jai Shankar, Rajnish K Chaturvedi, Ratan Singh Ray. Benzophenone 1 induced photogenotoxicity and apoptosis via release of cytochrome c and Smac/DIABLO at environmental UV radiation.
Toxicology letters.
2015 Dec; 239(3):182-93. doi:
10.1016/j.toxlet.2015.09.024
. [PMID: 26440554] - Bi-Ling Wu, Hui-Liang Zou, Fang-Min Qin, Hong-Yu Li, Guang-Xiong Zhou. New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.
Molecules (Basel, Switzerland).
2015 Dec; 20(12):22445-53. doi:
10.3390/molecules201219801
. [PMID: 26694331] - Germaine M Buck Louis, Zhen Chen, Sungduk Kim, Katherine J Sapra, Jisuk Bae, Kurunthachalam Kannan. Urinary concentrations of benzophenone-type ultraviolet light filters and semen quality.
Fertility and sterility.
2015 Oct; 104(4):989-996. doi:
10.1016/j.fertnstert.2015.07.1129
. [PMID: 26253817] - Thea K Kleinschmidt, Martin Haraldsson, Devaraj Basavarajappa, Erik Lundeberg, Madhuranayaki Thulasingam, Maria Ekoff, Alexander Fauland, Christoph Lehmann, Astrid S Kahnt, Lennart Lindbom, Jesper Z Haeggström. Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase.
The Journal of pharmacology and experimental therapeutics.
2015 Oct; 355(1):108-16. doi:
10.1124/jpet.115.227157
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Toxicology letters.
2015 Jun; 235(2):84-95. doi:
10.1016/j.toxlet.2015.03.008
. [PMID: 25800561] - Gang Chen, Kai-hua Wan, Hui-zheng Fu, Qing-wei Yan. [n-Butyl Alcohol-soluble Chemical Constituents of Psidium guajava Leaves].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2015 Mar; 38(3):521-3. doi:
"
. [PMID: 26495653] - Alan J House, Laura R Daye, Michael Tarpley, Kezia Addo, David S Lamson, Margie K Parker, Warren E Bealer, Kevin P Williams. Design and characterization of a photo-activatable hedgehog probe that mimics the natural lipidated form.
Archives of biochemistry and biophysics.
2015 Feb; 567(?):66-74. doi:
10.1016/j.abb.2014.12.014
. [PMID: 25529135] - Rebecca K Moos, Jürgen Angerer, Jürgen Wittsiepe, Michael Wilhelm, Thomas Brüning, Holger M Koch. Rapid determination of nine parabens and seven other environmental phenols in urine samples of German children and adults.
International journal of hygiene and environmental health.
2014 Nov; 217(8):845-53. doi:
10.1016/j.ijheh.2014.06.003
. [PMID: 25008406] - Sujin Kim, Kyungho Choi. Occurrences, toxicities, and ecological risks of benzophenone-3, a common component of organic sunscreen products: a mini-review.
Environment international.
2014 Sep; 70(?):143-57. doi:
10.1016/j.envint.2014.05.015
. [PMID: 24934855] - Theresa Beelders, Dalene de Beer, Maria A Stander, Elizabeth Joubert. Comprehensive phenolic profiling of Cyclopia genistoides (L.) Vent. by LC-DAD-MS and -MS/MS reveals novel xanthone and benzophenone constituents.
Molecules (Basel, Switzerland).
2014 Aug; 19(8):11760-90. doi:
10.3390/molecules190811760
. [PMID: 25105916] - V Lakshmi Ranganatha, A Bushra Begum, P Naveen, Farhan Zameer, Raghavendra Hegdekatte, Shaukath Ara Khanum. Synthesis, xanthine oxidase inhibition, and antioxidant screening of benzophenone tagged thiazolidinone analogs.
Archiv der Pharmazie.
2014 Aug; 347(8):589-98. doi:
10.1002/ardp.201400058
. [PMID: 24853493] - Irene See, Gwendoline Cheng Lian Ee, Soek Sin Teh, Arifah Abdul Kadir, Shaari Daud. Two new chemical constituents from the stem bark of Garcinia mangostana.
Molecules (Basel, Switzerland).
2014 Jun; 19(6):7308-16. doi:
10.3390/molecules19067308
. [PMID: 24901833] - Nargis Jamila, Melati Khairuddean, Nik Soriani Yaacob, Nik Nur Syazni Nik Mohamed Kamal, Hasnah Osman, Sadiq Noor Khan, Naeem Khan. Cytotoxic benzophenone and triterpene from Garcinia hombroniana.
Bioorganic chemistry.
2014 Jun; 54(?):60-7. doi:
10.1016/j.bioorg.2014.04.003
. [PMID: 24813683] - James T Lyles, Adam Negrin, Shabana I Khan, Kan He, Edward J Kennelly. In vitro antiplasmodial activity of benzophenones and xanthones from edible fruits of Garcinia species.
Planta medica.
2014 Jun; 80(8-9):676-81. doi:
10.1055/s-0034-1368585
. [PMID: 24963617] - F Vela-Soria, O Ballesteros, A Zafra-Gómez, L Ballesteros, A Navalón. UHPLC-MS/MS method for the determination of bisphenol A and its chlorinated derivatives, bisphenol S, parabens, and benzophenones in human urine samples.
Analytical and bioanalytical chemistry.
2014 Jun; 406(15):3773-85. doi:
10.1007/s00216-014-7785-9
. [PMID: 24710638] - Kristina Kotnik, Tina Kosjek, Uroš Krajnc, Ester Heath. Trace analysis of benzophenone-derived compounds in surface waters and sediments using solid-phase extraction and microwave-assisted extraction followed by gas chromatography-mass spectrometry.
Analytical and bioanalytical chemistry.
2014 May; 406(13):3179-90. doi:
10.1007/s00216-014-7749-0
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