Dimethyl sulfone (BioDeep_00000866166)

Main id: BioDeep_00000008513

 

PANOMIX_OTCML-2023 BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


methylsulfonylmethane

化学式: C2H6O2S (94.0088496)
中文名称: 二甲基砜
谱图信息: 最多检出来源 () 0%

Reviewed

Last reviewed on 2024-08-21.

Cite this Page

Dimethyl sulfone. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/dimethyl_sulfone (retrieved 2024-11-24) (BioDeep RN: BioDeep_00000866166). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CS(=O)(=O)C
InChI: InChI=1S/C2H6O2S/c1-5(2,3)4/h1-2H3

描述信息

C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D000893 - Anti-Inflammatory Agents
Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective[1][2][3].
Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective[1][2][3].

同义名列表

29 个代谢物同义名

Methylsulfonyl methane; Methane, sulfonylbis-; Methylsulfonylmethane; Methyl sulfone (8CI); Sulphonylbismethane; Sulfonylbismethane; Dimethyl sulphone; sulfonyldimethane; EINECS 200-665-9; Dimethyl sulfone; Dimethylsulfone; SPECTRUM1505358; NCGC00095990-01; M81705_ALDRICH; Methyl sulfone; MolMap_000019; ZINC04658606; mesylmethane; 41631_FLUKA; CCRIS 2938; CHEBI:9349; 54841-73-5; NSC 63345; AI3-25306; NSC63345; 67-71-0; C11142; Dimethyl sulfone; Dimethyl sulfone



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Elizabeth A Tanner, Melody A Gary, Stephan Michalik, Asheal A Davis, Brian K McFarlin. Optimized Curcumin, Pomegranate Extract, and Methylsulfonylmethane Reduce Acute, Systemic Inflammatory Response to a Half-marathon Race. Alternative therapies in health and medicine. 2022 Sep; 28(6):72-81. doi: . [PMID: 32619204]
  • Cameron V Fili, Ling Lin, Jonathan Chapman, David Hamilton, Charles R Yates. Methylsulfonylmethane and Sesame Seed Oil Improve Dyslipidemia and Modulate Polyunsaturated Fatty Acid Metabolism in Two Mouse Models of Diabetes. Journal of medicinal food. 2022 Jun; 25(6):607-617. doi: 10.1089/jmf.2021.0196. [PMID: 35708633]
  • Yueming Guo, Pengpeng Li, Zongliang Wang, Peibiao Zhang, Xiaodong Wu. Sustained Delivery of Methylsulfonylmethane from Biodegradable Scaffolds Enhances Efficient Bone Regeneration. International journal of nanomedicine. 2022; 17(?):4829-4842. doi: 10.2147/ijn.s377036. [PMID: 36246935]
  • Da-Yeon Lee, Chan-Yang Lee, Jin-Na Shin, Jeong-Ho Oh, Soon-Mi Shim. Impact of soy lecithin, zinc oxide, and methylsulfonylmethane, as excipient ingredients, on the bioaccessibility and intestinal transport of branched-chain amino acids from animal and plant protein mixtures. Food & function. 2021 Nov; 12(22):11399-11407. doi: 10.1039/d1fo01712h. [PMID: 34673869]
  • X Liu, S Robbins, J Eyles, T Fedorova, S Virk, L A Deveza, A J McLachlan, D J Hunter. Efficacy and safety of a supplement combination on hand pain among people with symptomatic hand osteoarthritis an internet-based, randomised clinical trial the RADIANT study. Osteoarthritis and cartilage. 2021 05; 29(5):667-677. doi: 10.1016/j.joca.2021.01.011. [PMID: 33617972]
  • M S Abdul Rasheed, U P Tiwari, J C Jespersen, L L Bauer, R N Dilger. Effects of methylsulfonylmethane and neutralizing anti-IL-10 antibody supplementation during a mild Eimeria challenge infection in broiler chickens. Poultry science. 2020 Dec; 99(12):6559-6568. doi: 10.1016/j.psj.2020.09.046. [PMID: 33248571]
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  • M S Abdul Rasheed, M L Oelschlager, B N Smith, L L Bauer, R A Whelan, R N Dilger. Dietary methylsulfonylmethane supplementation and oxidative stress in broiler chickens. Poultry science. 2020 Feb; 99(2):914-925. doi: 10.1016/j.psj.2019.12.010. [PMID: 32029168]
  • H L Yan, S C Cao, Y D Hu, H F Zhang, J B Liu. Effects of methylsulfonylmethane on growth performance, immunity, antioxidant capacity, and meat quality in Pekin ducks. Poultry science. 2020 Feb; 99(2):1069-1074. doi: 10.1016/j.psj.2019.10.002. [PMID: 32029143]
  • Xiaoqian Liu, David J Hunter, Jillian Eyles, Andrew J McLachlan, Jeffry Adiwidjaja, Shane K Eagles, XiaoSuo Wang. Pharmacokinetic assessment of constituents of Boswellia serrata, pine bark extracts, curcumin in combination including methylsulfonylmethane in healthy volunteers. The Journal of pharmacy and pharmacology. 2020 Jan; 72(1):121-131. doi: 10.1111/jphp.13184. [PMID: 31608447]
  • M S Abdul Rasheed, M L Oelschlager, B N Smith, L L Bauer, R A Whelan, R N Dilger. Toxicity and tissue distribution of methylsulfonylmethane following oral gavage in broilers. Poultry science. 2019 Oct; 98(10):4972-4981. doi: 10.3382/ps/pez265. [PMID: 31111938]
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  • Ranjith Kumar Velusamy, Ramasamy Tamizhselvi. Protective effect of methylsulfonylmethane in caerulein-induced acute pancreatitis and associated lung injury in mice. The Journal of pharmacy and pharmacology. 2018 Sep; 70(9):1188-1199. doi: 10.1111/jphp.12946. [PMID: 29971769]
  • Francisco Adelvane de Paulo Rodrigues, Alan Diego da Conceição Santos, Pedro Henrique Quintela Soares de Medeiros, Mara de Moura Gondim Prata, Tailane Caína de Souza Santos, James Almada da Silva, Gerly Anne de Castro Brito, Armênio Aguiar Dos Santos, Edilberto Rocha Silveira, Aldo Ângelo Moreira Lima, Alexandre Havt. Gingerol suppresses sepsis-induced acute kidney injury by modulating methylsulfonylmethane and dimethylamine production. Scientific reports. 2018 08; 8(1):12154. doi: 10.1038/s41598-018-30522-6. [PMID: 30108263]
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  • Tommaso Cai, Daniele Tiscione, Luca Gallelli, Paolo Verze, Alessandro Palmieri, Vincenzo Mirone, Riccardo Bartoletti, Gianni Malossini. Serenoa repens associated with selenium and lycopene extract and bromelain and methylsulfonylmethane extract are able to improve the efficacy of levofloxacin in chronic bacterial prostatitis patients. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica. 2016 Oct; 88(3):177-182. doi: 10.4081/aiua.2016.3.177. [PMID: 27711089]
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  • Keyvan Amirshahrokhi, Shahab Bohlooli. Effect of methylsulfonylmethane on paraquat-induced acute lung and liver injury in mice. Inflammation. 2013 Oct; 36(5):1111-21. doi: 10.1007/s10753-013-9645-8. [PMID: 23595869]
  • Rehab Kamel, Engy M El Morsy. Hepatoprotective effect of methylsulfonylmethane against carbon tetrachloride-induced acute liver injury in rats. Archives of pharmacal research. 2013 Sep; 36(9):1140-8. doi: 10.1007/s12272-013-0110-x. [PMID: 23591777]
  • Nadia Ms Arafa, Hayam M Hamuda, Samuel T Melek, Sahar K Darwish. The effectiveness of Echinacea extract or composite glucosamine, chondroitin and methyl sulfonyl methane supplements on acute and chronic rheumatoid arthritis rat model. Toxicology and industrial health. 2013 Mar; 29(2):187-201. doi: 10.1177/0748233711428643. [PMID: 22173958]
  • Pawel Mochalski, Karin Krapf, Clemens Ager, Helmut Wiesenhofer, Agapios Agapiou, Milt Statheropoulos, Dietmar Fuchs, Ernst Ellmerer, Boguslaw Buszewski, Anton Amann. Temporal profiling of human urine VOCs and its potential role under the ruins of collapsed buildings. Toxicology mechanisms and methods. 2012 Sep; 22(7):502-11. doi: 10.3109/15376516.2012.682664. [PMID: 22482743]
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