c0264 (BioDeep_00000862023)

Main id: BioDeep_00000003216

 

PANOMIX_OTCML-2023


代谢物信息卡片


InChI=1\C6H6O3\c7-4-1-2-5(8)6(9)3-4\h1-3,7-9

化学式: C6H6O3 (126.0317)
中文名称: 1,2,4-苯三酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C=C1O)O)O
InChI: InChI=1S/C6H6O3/c7-4-1-2-5(8)6(9)3-4/h1-3,7-9H

描述信息

1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes[1].
1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes[1].

同义名列表

29 个代谢物同义名

InChI=1\C6H6O3\c7-4-1-2-5(8)6(9)3-4\h1-3,7-9; 4-06-00-07338 (Beilstein Handbook Reference); 1,2,4-Trihydroxybenzene; Oxyhydrochinon [German]; 1,3,4-Trihydroxybenzene; Hydroquinone, hydroxy-; 2,5-Dihydroxyphenol; Benzene-1,2,4-triol; Hydroxyhydroquinone; 1,3,4-Benzenetriol; 1,2,4-BENZENETRIOL; 4-Hydroxycatechol; EINECS 208-575-1; Oxyhydroquinone; 173401_ALDRICH; WLN: QR BQ DQ; Hydroxyquinol; ZINC00388437; BRN 2042863; CHEBI:16971; CCRIS 2987; AI3-19361; 533-73-3; NSC 2818; NSC2818; C02814; c0264; Benzene-1,2,4-triol; 1,2,4-Benzenetriol



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(8)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, CAT, CNP, CRYZ, CYP2E1, HMBS, PML, TGM5, TYR
Peripheral membrane protein 3 CYP1B1, CYP2E1, PML
Endoplasmic reticulum membrane 4 CYP1B1, CYP2E1, PML, PROS1
Nucleus 4 ALB, GATA1, MPO, PML
cytosol 6 ALB, CAT, CRYZ, HBB, HMBS, PML
centrosome 1 ALB
nucleoplasm 3 GATA1, MPO, PML
Cell membrane 2 CHRNA7, FCER1G
Lipid-anchor 1 CNP
Cytoplasmic side 1 PML
Early endosome membrane 1 PML
Multi-pass membrane protein 1 CHRNA7
Synapse 2 CHRNA7, CNP
cell surface 1 FCER1G
Golgi apparatus 1 ALB
Golgi membrane 1 PROS1
mitochondrial inner membrane 2 CNP, CYP2E1
postsynapse 1 CHRNA7
Lysosome 2 MPO, TYR
plasma membrane 4 CHRNA7, FCER1G, PROS1, TGM5
Membrane 7 CAT, CHRNA7, CNP, CYP1B1, DGCR2, HBB, TMEM131
extracellular exosome 7 ALB, CAT, CNP, CRYZ, HBB, MPO, PROS1
endoplasmic reticulum 2 ALB, PROS1
extracellular space 5 ALB, CNP, HBB, MPO, PROS1
perinuclear region of cytoplasm 2 CNP, TYR
mitochondrion 3 CAT, CRYZ, CYP1B1
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 5 CAT, CYP1B1, CYP2E1, MPO, TYR
Microsome membrane 2 CYP1B1, CYP2E1
Single-pass type I membrane protein 3 FCER1G, TMEM131, TYR
Secreted 2 ALB, PROS1
extracellular region 6 ALB, CAT, DNAH9, HBB, MPO, PROS1
mitochondrial outer membrane 1 CNP
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
transcription regulator complex 1 GATA1
motile cilium 1 DNAH9
nuclear membrane 1 PML
external side of plasma membrane 1 FCER1G
nucleolus 1 PML
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
postsynaptic membrane 1 CHRNA7
Mitochondrion inner membrane 1 CYP2E1
focal adhesion 1 CAT
microtubule 2 CNP, DNAH9
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 PML
PML body 1 PML
secretory granule 1 MPO
axoneme 1 DNAH9
Postsynaptic cell membrane 1 CHRNA7
neuron projection 1 CHRNA7
ciliary basal body 1 ALB
chromatin 1 GATA1
centriole 1 ALB
spindle pole 1 ALB
chromosome, telomeric region 1 PML
blood microparticle 3 ALB, HBB, PROS1
Cytoplasm, cytoskeleton, cilium axoneme 1 DNAH9
microvillus 1 CNP
tertiary granule membrane 1 FCER1G
Melanosome 2 CNP, TYR
pseudopodium 1 CNP
azurophil granule 1 MPO
plasma membrane raft 1 CHRNA7
ficolin-1-rich granule lumen 2 CAT, HBB
secretory granule lumen 1 CAT
Golgi lumen 1 PROS1
endoplasmic reticulum lumen 1 ALB
nuclear matrix 1 PML
transcription repressor complex 1 GATA1
platelet alpha granule lumen 2 ALB, PROS1
tertiary granule lumen 1 HBB
azurophil granule lumen 1 MPO
9+2 motile cilium 1 DNAH9
dynein complex 1 DNAH9
phagocytic vesicle lumen 1 MPO
protein-DNA complex 1 GATA1
ficolin-1-rich granule membrane 1 FCER1G
hemoglobin complex 1 HBB
endocytic vesicle lumen 1 HBB
haptoglobin-hemoglobin complex 1 HBB
acetylcholine-gated channel complex 1 CHRNA7
catalase complex 1 CAT
myelin sheath abaxonal region 1 CNP
myelin sheath adaxonal region 1 CNP
Fc-gamma receptor III complex 1 FCER1G
Fc-epsilon receptor I complex 1 FCER1G
ciliary transition fiber 1 ALB
outer dynein arm 1 DNAH9
distal portion of axoneme 1 DNAH9


文献列表

  • Masato Kajikawa, Tatsuya Maruhashi, Takayuki Hidaka, Yukiko Nakano, Satoshi Kurisu, Takeshi Matsumoto, Yumiko Iwamoto, Shinji Kishimoto, Shogo Matsui, Yoshiki Aibara, Farina Mohamad Yusoff, Yasuki Kihara, Kazuaki Chayama, Chikara Goto, Kensuke Noma, Ayumu Nakashima, Takuya Watanabe, Hiroshi Tone, Masanobu Hibi, Noriko Osaki, Yoshihisa Katsuragi, Yukihito Higashi. Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension. European journal of nutrition. 2019 Apr; 58(3):989-996. doi: 10.1007/s00394-018-1611-7. [PMID: 29330659]
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  • Shun Katada, Takuya Watanabe, Tomohito Mizuno, Shinichi Kobayashi, Masao Takeshita, Noriko Osaki, Shigeru Kobayashi, Yoshihisa Katsuragi. Effects of Chlorogenic Acid-Enriched and Hydroxyhydroquinone-Reduced Coffee on Postprandial Fat Oxidation and Antioxidative Capacity in Healthy Men: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial. Nutrients. 2018 Apr; 10(4):. doi: 10.3390/nu10040525. [PMID: 29690626]
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