cefaloridine (BioDeep_00000858472)

Main id: BioDeep_00000008850

 


代谢物信息卡片


cephaloridine

化学式: C19H17N3O4S2 (415.0660442)
中文名称: 头孢噻啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(=C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=CC=C4
InChI: InChI=1S/C19H17N3O4S2/c23-14(9-13-5-4-8-27-13)20-15-17(24)22-16(19(25)26)12(11-28-18(15)22)10-21-6-2-1-3-7-21/h1-8,15,18H,9-11H2,(H-,20,23,25,26)/t15-,18-/m1/s1

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DB - First-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
Same as: D01075

同义名列表

2 个代谢物同义名

cephaloridine; cefaloridine



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Kazuharu Ienaga, Chan Hum Park, Takako Yokozawa. Protective effect of an intrinsic antioxidant, HMH (5-hydroxy-1-methylhydantoin; NZ-419), against cellular damage of kidney tubules. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 2013 Jul; 65(5):559-66. doi: 10.1016/j.etp.2012.05.001. [PMID: 22749566]
  • Aurijit Sarkar, Kelcey C Anderson, Glen E Kellogg. Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics. European journal of medicinal chemistry. 2012 Jun; 52(?):98-110. doi: 10.1016/j.ejmech.2012.03.008. [PMID: 22483632]
  • Arianna Chiusolo, Rossella Defazio, Edoardo Zanetti, Michele Mongillo, Nadia Mori, Patrizia Cristofori, Andrea Trevisan. Kidney injury molecule-1 expression in rat proximal tubule after treatment with segment-specific nephrotoxicants: a tool for early screening of potential kidney toxicity. Toxicologic pathology. 2010 Apr; 38(3):338-45. doi: 10.1177/0192623310362244. [PMID: 20305092]
  • Takashi Kano, Yukio Kato, Kimihiro Ito, Takuo Ogihara, Yoshiyuki Kubo, Akira Tsuji. Carnitine/organic cation transporter OCTN2 (Slc22a5) is responsible for renal secretion of cephaloridine in mice. Drug metabolism and disposition: the biological fate of chemicals. 2009 May; 37(5):1009-16. doi: 10.1124/dmd.108.025015. [PMID: 19220985]
  • Ines Schneider, Emma Keuleyan, Rudolf Rasshofer, Rumyana Markovska, Anne Marie Queenan, Adolf Bauernfeind. VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. Antimicrobial agents and chemotherapy. 2008 Aug; 52(8):2977-9. doi: 10.1128/aac.00175-08. [PMID: 18519714]
  • R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1385-405. doi: 10.1124/dmd.108.020479. [PMID: 18426954]
  • Masatomo Rokushima, Kae Fujisawa, Naoko Furukawa, Fumio Itoh, Toru Yanagimoto, Ryou Fukushima, Akiko Araki, Manabu Okada, Mikinori Torii, Ikuo Kato, Jun Ishizaki, Kazuo Omi. Transcriptomic analysis of nephrotoxicity induced by cephaloridine, a representative cephalosporin antibiotic. Chemical research in toxicology. 2008 Jun; 21(6):1186-96. doi: 10.1021/tx800008e. [PMID: 18500788]
  • Hiromi Suzuki, Tomoaki Inoue, Tomochika Matsushita, Kazuko Kobayashi, Ikuo Horii, Yoko Hirabayashi, Tohru Inoue. In vitro gene expression analysis of nephrotoxic drugs in rat primary renal cortical tubular cells. Journal of applied toxicology : JAT. 2008 Mar; 28(2):237-48. doi: 10.1002/jat.1329. [PMID: 18172885]
  • Kazuo Nakamura, Kimihiro Ito, Yukio Kato, Takeshi Sugaya, Yoshiyuki Kubo, Akira Tsuji. L-type fatty acid binding protein transgenic mouse as a novel tool to explore cytotoxicity to renal proximal tubules. Drug metabolism and pharmacokinetics. 2008; 23(4):271-8. doi: 10.2133/dmpk.23.271. [PMID: 18762714]
  • Yuka Kohda, Yoshiko Matsunaga, Katsuya Yonogi, Yoshiko Kawai, Akira Awaya, Munekazu Gemba. Protective effect of serum thymic factor, FTS, on cephaloridine-induced nephrotoxicity in rats. Biological & pharmaceutical bulletin. 2005 Nov; 28(11):2087-91. doi: 10.1248/bpb.28.2087. [PMID: 16272694]
  • Yuka Kohda, Yoshiko Kawai, Noriaki Iwamoto, Yoshiko Matsunaga, Hiromi Aiga, Akira Awaya, Munekazu Gemba. Serum thymic factor, FTS, attenuates cisplatin nephrotoxicity by suppressing cisplatin-induced ERK activation. Biochemical pharmacology. 2005 Nov; 70(9):1408-16. doi: 10.1016/j.bcp.2005.08.002. [PMID: 16154539]
  • Jérôme Guitton, Agnès Conjard, Assaad Eid, Mireille Martin, Michelle Boghossian, Hélène Delage, Gabriel Baverel, Bernard Ferrier. Identification of novel targets of cephaloridine in rabbit renal proximal tubules synthesizing glutamine from alanine. Archives of toxicology. 2005 Oct; 79(10):587-94. doi: 10.1007/s00204-005-0673-5. [PMID: 15991025]
  • Yoshiko Kawai, Yuka Kohda, Takaaki Kodawara, Munekazu Gemba. Protective effect of a protein kinase inhibitor on cellular injury induced by cephaloridine in the porcine kidney cell line LLC-PK(1). The Journal of toxicological sciences. 2005 Aug; 30(3):157-63. doi: 10.2131/jts.30.157. [PMID: 16141650]
  • Yuka Kohda, Munekazu Gemba. Cephaloridine induces translocation of protein kinase C delta into mitochondria and enhances mitochondrial generation of free radicals in the kidney cortex of rats causing renal dysfunction. Journal of pharmacological sciences. 2005 May; 98(1):49-57. doi: 10.1254/jphs.fp0040926. [PMID: 15879677]
  • Petra Luckner, Matthias Brandsch. Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2005 Jan; 59(1):17-24. doi: 10.1016/j.ejpb.2004.07.008. [PMID: 15567297]
  • C Cojocel, M S Thomson. Protective effect of resveratrol against 6-hydroxydopamine-induced impairment of renal p-aminohippurate transport. Archives of toxicology. 2004 Sep; 78(9):525-32. doi: 10.1007/s00204-004-0566-z. [PMID: 15071722]
  • Yuka Kohda, Jun Hiramatsu, Munekazu Gemba. Involvement of MEK/ERK pathway in cephaloridine-induced injury in rat renal cortical slices. Toxicology letters. 2003 Jul; 143(2):185-94. doi: 10.1016/s0378-4274(03)00174-7. [PMID: 12749822]
  • Suparat Khamdang, Michio Takeda, Ellappan Babu, Rie Noshiro, Maristela Lika Onozato, Akihiro Tojo, Atsushi Enomoto, Xiu-Lin Huang, Shinichi Narikawa, Naohiko Anzai, Pawinee Piyachaturawat, Hitoshi Endou. Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. European journal of pharmacology. 2003 Mar; 465(1-2):1-7. doi: 10.1016/s0014-2999(03)01381-5. [PMID: 12650826]
  • Ken-ichi Kiyomiya, Naoko Matsushita, Masaru Kurebe, Hiroshi Nakagawa, Saburou Matsuo. Mitochondrial cytochrome c oxidase as a target site for cephalosporin antibiotics in renal epithelial cells (LLC-PK(1)) and renal cortex. Life sciences. 2002 Nov; 72(1):49-57. doi: 10.1016/s0024-3205(02)02181-1. [PMID: 12409144]
  • Yuka Kohda, Munekazu Gemba. Enhancement of protein kinase C activity and chemiluminescence intensity in mitochondria isolated from the kidney cortex of rats treated with cephaloridine. Biochemical pharmacology. 2002 Aug; 64(3):543-9. doi: 10.1016/s0006-2952(02)01216-9. [PMID: 12147306]
  • Michio Takeda, Ellappan Babu, Shinichi Narikawa, Hitoshi Endou. Interaction of human organic anion transporters with various cephalosporin antibiotics. European journal of pharmacology. 2002 Mar; 438(3):137-42. doi: 10.1016/s0014-2999(02)01306-7. [PMID: 11909604]
  • Kyu Yong Jung, Michio Takeda, Minoru Shimoda, Shinichi Narikawa, Akihiro Tojo, Do Kyung Kim, Arthit Chairoungdua, Bong Kyu Choi, Hiroyuki Kusuhara, Yuichi Sugiyama, Takashi Sekine, Hitoshi Endou. Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: in comparison with rOAT1. Life sciences. 2002 Mar; 70(16):1861-74. doi: 10.1016/s0024-3205(02)01500-x. [PMID: 12005172]
  • T Furuno, T Kanno, K Arita, M Asami, T Utsumi, Y Doi, M Inoue, K Utsumi. Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition. Biochemical pharmacology. 2001 Oct; 62(8):1037-46. doi: 10.1016/s0006-2952(01)00745-6. [PMID: 11597572]
  • S Ohnishi, H Saito, A Fukada, K I Inui. Independent organic cation transport activity of Na(+)-L-carnitine cotransport system in LLC-PK(1) cells. American journal of physiology. Renal physiology. 2001 Aug; 281(2):F273-9. doi: 10.1152/ajprenal.2001.281.2.f273. [PMID: 11457718]
  • C Stahl, S Kubetzko, I Kaps, S Seeber, H Engelhardt, M Niederweis. MspA provides the main hydrophilic pathway through the cell wall of Mycobacterium smegmatis. Molecular microbiology. 2001 Apr; 40(2):451-64. doi: 10.1046/j.1365-2958.2001.02394.x. [PMID: 11309127]
  • Y Kohda, M Gemba. Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices. Japanese journal of pharmacology. 2001 Jan; 85(1):54-9. doi: 10.1254/jjp.85.54. [PMID: 11243575]
  • D S Snyder, T J McIntosh. The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics. Biochemistry. 2000 Sep; 39(38):11777-87. doi: 10.1021/bi000810n. [PMID: 10995246]
  • K Kiyomiya, N Matsushita, S Matsuo, M Kurebe. Cephaloridine-induced inhibition of cytochrome c oxidase activity in the mitochondria of cultured renal epithelial cells (LLC-PK(1)) as a possible mechanism of its nephrotoxicity. Toxicology and applied pharmacology. 2000 Sep; 167(2):151-6. doi: 10.1006/taap.2000.8981. [PMID: 10964766]
  • K Kiyomiya, N Matsushita, S Matsuo, M Kurebe. Roles of oxygen radical production and lipid peroxidation in the cytotoxicity of cephaloridine on cultured renal epithelial cells (LLC-PK1). The Journal of veterinary medical science. 2000 Sep; 62(9):977-81. doi: 10.1292/jvms.62.977. [PMID: 11039594]
  • R Hori, M Shimakura, Y Aramata, K Kizawa, I Nozawa, M Takahata, S Minami. [Nephrotoxicity of piperacillin combined with furosemide in rats]. The Japanese journal of antibiotics. 2000 Aug; 53(8):582-91. doi: NULL. [PMID: 11070820]
  • T Cihlar, E S Ho. Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1. Analytical biochemistry. 2000 Jul; 283(1):49-55. doi: 10.1006/abio.2000.4633. [PMID: 10929807]
  • M E Ganapathy, W Huang, D P Rajan, A L Carter, M Sugawara, K Iseki, F H Leibach, V Ganapathy. beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. The Journal of biological chemistry. 2000 Jan; 275(3):1699-707. doi: 10.1074/jbc.275.3.1699. [PMID: 10636865]
  • M Takeda, A Tojo, T Sekine, M Hosoyamada, Y Kanai, H Endou. Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity. Kidney international. 1999 Dec; 56(6):2128-36. doi: 10.1046/j.1523-1755.1999.00789.x. [PMID: 10594788]
  • S Jariyawat, T Sekine, M Takeda, N Apiwattanakul, Y Kanai, S Sophasan, H Endou. The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. The Journal of pharmacology and experimental therapeutics. 1999 Aug; 290(2):672-7. doi: . [PMID: 10411577]
  • H Yabuuchi, I Tamai, J Nezu, K Sakamoto, A Oku, M Shimane, Y Sai, A Tsuji. Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations. The Journal of pharmacology and experimental therapeutics. 1999 May; 289(2):768-73. doi: . [PMID: 10215651]
  • T Yokozawa, S Owada. Effect of ginsenoside-Rd in cephaloridine-induced renal disorder. Nephron. 1999 Feb; 81(2):200-7. doi: 10.1159/000045277. [PMID: 9933756]
  • T Yokozawa, E Dong, Z W Liu, T Shibata, M Hasegawa, H Watanabe, H Oura. Magnesium lithospermate B ameliorates cephaloridine-induced renal injury. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 1997 Dec; 49(5):337-41. doi: 10.1016/s0940-2993(97)80100-5. [PMID: 9455678]
  • M Valentovic, J G Ball, B A Rogers, M K Meadows, R C Harmon, J Moles. Cephaloridine in vitro toxicity and accumulation in renal slices from normoglycemic and diabetic rats. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1997 Aug; 38(2):184-90. doi: 10.1006/faat.1997.2349. [PMID: 9299192]
  • C Bolon, C Gauthier, H Simonnet, G Baverel. Advantages of a two-chamber culture system to test drug nephrotoxicity: the example of cephaloridine. Kidney & blood pressure research. 1997; 20(4):264-70. doi: 10.1159/000174156. [PMID: 9398033]
  • J P Morin, S Marouillat, C Lendormi, C Monteil. Comparative impact of cephaloridine on glutathione and related enzymes in LLC-PK1, LLC-RK1, and primary cultures of rat and rabbit proximal tubule cells. Cell biology and toxicology. 1996 Dec; 12(4-6):275-82. doi: 10.1007/bf00438158. [PMID: 9034621]
  • Y Kawai, M Gemba. Amelioration by cAMP of cephaloridine-induced injury in the porcine kidney cell line LLC-PK1. Japanese journal of pharmacology. 1996 Sep; 72(1):67-70. doi: 10.1254/jjp.72.67. [PMID: 8902601]
  • M A Valentovic, J G Ball, B A Rogers. Comparison of cephaloridine renal accumulation and urinary excretion between normoglycemic and diabetic animals. Toxicology. 1996 Apr; 108(1-2):93-9. doi: 10.1016/0300-483x(95)03295-q. [PMID: 8644123]
  • A R Kraynak, R D Storer, R D Jensen, M W Kloss, K A Soper, J H Clair, J G DeLuca, W W Nichols, R S Eydelloth. Extent and persistence of streptozotocin-induced DNA damage and cell proliferation in rat kidney as determined by in vivo alkaline elution and BrdUrd labeling assays. Toxicology and applied pharmacology. 1995 Dec; 135(2):279-86. doi: 10.1006/taap.1995.1234. [PMID: 8545838]
  • T Yamada. [Studies on the mechanisms of renal damages induced by nephrotoxic compounds]. Nihon hoigaku zasshi = The Japanese journal of legal medicine. 1995 Dec; 49(6):447-57. doi: . [PMID: 8583688]
  • S Halligan, S J Byard, A J Spencer, T J Gray, E S Harpur, F W Bonner. A study of the nephrotoxicity of three cephalosporins in rabbits using 1H NMR spectroscopy. Toxicology letters. 1995 Nov; 81(1):15-21. doi: 10.1016/0378-4274(95)03399-8. [PMID: 8525494]
  • H Kurota, M Yamaguchi. Suppressed expression of calcium-binding protein regucalcin mRNA in the renal cortex of rats with chemically induced kidney damage. Molecular and cellular biochemistry. 1995 Oct; 151(1):55-60. doi: 10.1007/bf01076896. [PMID: 8584014]
  • B M Tune. Effects of L-carnitine on the renal tubular transport of cephaloridine. Biochemical pharmacology. 1995 Aug; 50(4):562-4. doi: 10.1016/0006-2952(95)00169-z. [PMID: 7646563]
  • P W Harvey, G Healing, I R Major, M McFarlane, K A Purdy, O Olatunde, M T Garcia Conesa, D J Everett, A Cockburn. Glucocorticoid amelioration of nephrotoxicity: a study of cephaloridine-methylprednisolone interaction in the rat. Human & experimental toxicology. 1995 Jul; 14(7):554-61. doi: 10.1177/096032719501400702. [PMID: 7576815]
  • M A Valentovic, J G Ball. Cephaloridine nephrotoxicity in diabetic rats: modulation by insulin treatment. Toxicology. 1995 Jun; 100(1-3):11-6. doi: 10.1016/0300-483x(95)03031-a. [PMID: 7624867]
  • B M Tune, C Y Hsu. Toxicity of cephalosporins to fatty acid metabolism in rabbit renal cortical mitochondria. Biochemical pharmacology. 1995 Mar; 49(5):727-34. doi: 10.1016/0006-2952(94)00497-a. [PMID: 7887988]
  • F Moritz, S Marouillat, C Monteil, A Baudelot, J P Fillastre, G Bonmarchand, J P Morin. Impact of cephaloridine on glutathione and related enzymes: comparison of in vivo and in vitro rat models. Archives of toxicology. 1995; 70(2):104-11. doi: 10.1007/bf02733670. [PMID: 8773182]
  • H Dutertre-Catella, C Martin, M Debray, C Pham-Huy, M Thevenin, J M Warnet, R A Podevin, J R Claude. Rabbit renal proximal tubule suspensions as a model for nephrotoxicity evaluation of native or in situ metabolized beta-lactam antibiotics. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. 1995; 17(?):215-7. doi: 10.1007/978-3-642-79451-3_19. [PMID: 7786159]
  • L H Lash, J J Tokarz, E B Woods. Renal cell type specificity of cephalosporin-induced cytotoxicity in suspensions of isolated proximal tubular and distal tubular cells. Toxicology. 1994 Nov; 94(1-3):97-118. doi: 10.1016/0300-483x(94)90031-0. [PMID: 7801333]
  • B M Tune, C Y Hsu. Toxicity of cephaloridine to carnitine transport and fatty acid metabolism in rabbit renal cortical mitochondria: structure-activity relationships. The Journal of pharmacology and experimental therapeutics. 1994 Sep; 270(3):873-80. doi: . [PMID: 7932199]
  • Y Hirouchi, H Naganuma, Y Kawahara, R Okada, A Kamiya, K Inui, R Hori. Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex. Japanese journal of pharmacology. 1994 Sep; 66(1):1-6. doi: 10.1254/jjp.66.1. [PMID: 7861655]
  • K Nagashima, H Kusaka, K Sato, A Karasawa. Effects of KW-3902, a novel adenosine A1-receptor antagonist, on cephaloridine-induced acute renal failure in rats. Japanese journal of pharmacology. 1994 Jan; 64(1):9-17. doi: 10.1254/jjp.64.9. [PMID: 8164396]
  • D M Miller, J S Woods. Urinary porphyrins as biological indicators of oxidative stress in the kidney. Interaction of mercury and cephaloridine. Biochemical pharmacology. 1993 Dec; 46(12):2235-41. doi: 10.1016/0006-2952(93)90614-3. [PMID: 8274157]
  • Y Hirouchi, H Naganuma, Y Kawahara, R Okada, A Kamiya, K Inui, R Hori. Protective effect of N-acyl amino acids (NAAs) on cephaloridine (CER) nephrotoxicity in rabbits. Japanese journal of pharmacology. 1993 Dec; 63(4):487-93. doi: 10.1254/jjp.63.487. [PMID: 7509889]
  • M L Anthony, C R Beddell, J C Lindon, J K Nicholson. Raised transaminase activity of blood plasma from rats with experimentally-induced kidney damage detected by spin-echo 1H-NMR spectroscopy. Journal of pharmaceutical and biomedical analysis. 1993 Oct; 11(10):897-902. doi: 10.1016/0731-7085(93)80047-5. [PMID: 8305593]
  • N Furuta, J Nakada. [Study on gamma-GTP activity in urine and renal tissue of drug-induced nephrotoxicity in rats]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology. 1993 Jul; 84(7):1197-205. doi: 10.5980/jpnjurol1989.84.1197. [PMID: 8102655]
  • S E Kays, W A Crowell, M A Johnson. Cephaloridine nephrotoxicity is potentiated by selenium deficiency but not copper deficiency in rats. The Journal of nutrition. 1992 Jun; 122(6):1232-41. doi: 10.1093/jn/122.6.1232. [PMID: 1588439]
  • F Inage, M Kato, M Yoshida, K Akahane, S Takayama. Lack of nephrotoxic effects of the new quinolone antibacterial agent levofloxacin in rabbits. Arzneimittel-Forschung. 1992 Mar; 43(3A):395-7. doi: NULL. [PMID: 1622439]
  • M A Valentovic, W Jeffrey, J G Ball, D Bailly, M Morenas, J Kinder. Comparative studies of in vitro renal cephaloridine toxicity between normoglycemic and diabetic rats. Journal of applied toxicology : JAT. 1992 Feb; 12(1):19-24. doi: 10.1002/jat.2550120106. [PMID: 1564248]
  • G F Rush, R A Heim, G D Ponsler, J Engelhardt. Cephaloridine-induced renal pathological and biochemical changes in female rabbits and isolated proximal tubules in suspension. Toxicologic pathology. 1992; 20(2):155-68. doi: 10.1177/019262339202000203. [PMID: 1475577]
  • L B Murgatroyd, R J Pickford, I K Smith, I D Wilson, B J Middleton. 1H-NMR spectroscopy as a means of monitoring nephrotoxicity as exemplified by studies with cephaloridine. Human & experimental toxicology. 1992 Jan; 11(1):35-41. doi: 10.1177/096032719201100105. [PMID: 1354458]
  • P J Sausen, A A Elfarra, A J Cooley. Methimazole protection of rats against chemically induced kidney damage in vivo. The Journal of pharmacology and experimental therapeutics. 1992 Jan; 260(1):393-401. doi: NULL. [PMID: 1731048]
  • M Valentovic, J G Ball, D Anestis. Contribution of acetone and osmotic-diuresis by streptozotocin-induced diabetes in attenuation of cephaloridine nephrotoxicity. Toxicology. 1992; 71(3):245-55. doi: 10.1016/0300-483x(92)90027-c. [PMID: 1736416]
  • M L Anthony, K P Gartland, C R Beddell, J C Lindon, J K Nicholson. Cephaloridine-induced nephrotoxicity in the Fischer 344 rat: proton NMR spectroscopic studies of urine and plasma in relation to conventional clinical chemical and histopathological assessments of nephronal damage. Archives of toxicology. 1992; 66(8):525-37. doi: 10.1007/bf01973382. [PMID: 1463387]
  • J L Rosner, T J Chai, J Foulds. Regulation of ompF porin expression by salicylate in Escherichia coli. Journal of bacteriology. 1991 Sep; 173(18):5631-8. doi: 10.1128/jb.173.18.5631-5638.1991. [PMID: 1715858]
  • R K Chaudhary, A K Srivastava, J K Malik. Pharmacokinetics of cephaloridine in Bubalus bubalis. Journal of veterinary pharmacology and therapeutics. 1991 Jun; 14(2):200-5. doi: 10.1111/j.1365-2885.1991.tb00823.x. [PMID: 1920608]
  • T Schutz, R González-Méndez, D C Nabseth, B M Tune, O Jardetzky, D K Stevenson. A study of nephrotoxin-induced acute tubular necrosis with 31P magnetic resonance spectroscopy. Magnetic resonance in medicine. 1991 Mar; 18(1):159-68. doi: 10.1002/mrm.1910180116. [PMID: 2062227]
  • G O Rankin, V J Teets, D W Nicoll, P I Brown. Interactions among nephrotoxicants: N-(3,5-dichlorophenyl)succinimide and cephaloridine. Toxicology. 1991 Feb; 66(1):47-62. doi: 10.1016/0300-483x(91)90177-3. [PMID: 1996467]
  • P P Sokol. Effect of DQ-2556, a new cephalosporin, on organic ion transport in renal plasma membrane vesicles from the dog, rabbit and rat. The Journal of pharmacology and experimental therapeutics. 1990 Nov; 255(2):436-41. doi: NULL. [PMID: 2147035]
  • T Harauchi, T Yoshizaki. A method for determining urinary enzyme activities as nephrotoxic indicators in rats. Japanese journal of pharmacology. 1990 Oct; 54(2):205-15. doi: 10.1254/jjp.54.205. [PMID: 1981795]
  • J D Swann, D Acosta. Failure of gentamicin to elevate cellular malondialdehyde content or increase generation of intracellular reactive oxygen species in primary cultures of renal cortical epithelial cells. Biochemical pharmacology. 1990 Oct; 40(7):1523-6. doi: 10.1016/0006-2952(90)90449-u. [PMID: 2222507]
  • G Gstraunthaler, D Steinmassl, W Pfaller. Renal cell cultures: a tool for studying tubular function and nephrotoxicity. Toxicology letters. 1990 Sep; 53(1-2):1-7. doi: 10.1016/0378-4274(90)90085-z. [PMID: 2219147]
  • G F Rush, G D Ponsler. Biochemical mechanisms of cephaloridine nephrotoxicity in suspensions of isolated rabbit proximal tubules. Toxicology letters. 1990 Sep; 53(1-2):215-7. doi: 10.1016/0378-4274(90)90130-e. [PMID: 2219171]
  • M C Browning. Effect of verapamil on cephaloridine nephrotoxicity in the rabbit. Toxicology and applied pharmacology. 1990 May; 103(3):383-8. doi: 10.1016/0041-008x(90)90311-h. [PMID: 2339412]
  • S Suerbaum, H Leying, B Meyer, W Opferkuch. Influence of beta-lactam antibiotics on serum resistance of K1-positive blood culture isolates of Escherichia coli. Antimicrobial agents and chemotherapy. 1990 Apr; 34(4):628-31. doi: 10.1128/aac.34.4.628. [PMID: 2188587]
  • Y Suzuki, J Sudo. Lipid peroxidation and generations of oxygen radicals induced by cephaloridine in renal cortical microsomes of rats. Japanese journal of pharmacology. 1990 Feb; 52(2):233-43. doi: 10.1254/jjp.52.233. [PMID: 2313932]
  • B M Tune, C Y Hsu. The renal mitochondrial toxicity of cephalosporins: specificity of the effect on anionic substrate uptake. The Journal of pharmacology and experimental therapeutics. 1990 Jan; 252(1):65-9. doi: . [PMID: 2299604]
  • M F Olivier, H Dutertre-Catella, M Thevenin, C Martin, J M Warnet, J R Claude. Increased reduced glutathione and glutathione S-transferase activity in chronic cephaloridine nephrotoxicity studies in the rat. Drug and chemical toxicology. 1990; 13(2-3):209-19. doi: 10.3109/01480549009018121. [PMID: 1980456]
  • L H Lash, J J Tokarz. Isolation of two distinct populations of cells from rat kidney cortex and their use in the study of chemical-induced toxicity. Analytical biochemistry. 1989 Nov; 182(2):271-9. doi: 10.1016/0003-2697(89)90593-9. [PMID: 2692474]
  • K Bauer, M Struyvé, D Bosch, R Benz, J Tommassen. One single lysine residue is responsible for the special interaction between polyphosphate and the outer membrane porin PhoE of Escherichia coli. The Journal of biological chemistry. 1989 Oct; 264(28):16393-8. doi: 10.1016/s0021-9258(19)84719-1. [PMID: 2476443]
  • Y Suzuki, J Sudo. Changes in glutathione peroxidase system and pyridine nucleotide phosphate levels in kidneys of cephaloridine-administered rats. Japanese journal of pharmacology. 1989 Oct; 51(2):181-9. doi: 10.1254/jjp.51.181. [PMID: 2593376]
  • J C Topham, L B Murgatroyd, D V Jones, U R Goonetilleke, J Wright. Safety evaluation of meropenem in animals: studies on the kidney. The Journal of antimicrobial chemotherapy. 1989 Sep; 24 Suppl A(?):287-306. doi: 10.1093/jac/24.suppl_a.287. [PMID: 2681127]
  • M A Valentovic, J G Ball, C Elliott, E Madan. Cephaloridine nephrotoxicity in streptozotocin induced diabetic Fischer 344 (F344) rats. Toxicology. 1989 Jul; 57(2):193-207. doi: 10.1016/0300-483x(89)90165-0. [PMID: 2749746]
  • B M Tune, D Fravert, C Y Hsu. Oxidative and mitochondrial toxic effects of cephalosporin antibiotics in the kidney. A comparative study of cephaloridine and cephaloglycin. Biochemical pharmacology. 1989 Mar; 38(5):795-802. doi: 10.1016/0006-2952(89)90233-5. [PMID: 2930580]
  • R R Sierra, A M Torres, R B Rodriguez, I M Albelo. [Acute renal failure caused by ceporin, kanamycin and gentamicin]. Urologiia i nefrologiia. 1989 Mar; ?(2):50-3. doi: . [PMID: 2728142]
  • T Hayashi, J Sudo. Relieving effect of saline on cephaloridine nephrotoxicity in rats. Chemical & pharmaceutical bulletin. 1989 Mar; 37(3):785-90. doi: 10.1248/cpb.37.785. [PMID: 2752494]
  • H P Satink, J Hessels, A W Kingma, G A van den Berg, F A Muskiet, M R Halie. Microbial influences on urinary polyamine excretion. Clinica chimica acta; international journal of clinical chemistry. 1989 Feb; 179(3):305-14. doi: 10.1016/0009-8981(89)90093-4. [PMID: 2714003]
  • Y Kuwagaki, J Sudo. Influence of endogenous and exogenous Jaffé-reaction-positive pseudo-creatinine chromogens in determination of creatinine in blood of normal and cephaloridine-administered rats. The Journal of toxicological sciences. 1989 Feb; 14(1):23-31. doi: 10.2131/jts.14.23. [PMID: 2738963]
  • Y Suzuki, J Sudo. Changes in lipid peroxidation and activities of xanthine oxidase, superoxide dismutase and catalase in kidneys of cephaloridine-administered rats. Japanese journal of pharmacology. 1989 Jan; 49(1):43-51. doi: 10.1254/jjp.49.43. [PMID: 2724682]
  • R K Chaudhary, A K Srivastava. Disposition and dosage regimen of cephaloridine in calves. Veterinary research communications. 1989; 13(4):325-9. doi: 10.1007/bf00420839. [PMID: 2781723]
  • W Kramer, C Cojocel, D Mayer. Specific alterations of rat renal microsomal proteins induced by cephaloridine. Biochemical pharmacology. 1988 Nov; 37(21):4135-40. doi: 10.1016/0006-2952(88)90107-4. [PMID: 3190753]
  • C Cojocel, W Kramer, D Mayer. Depletion of cytochrome P-450 and alterations in activities of drug metabolizing enzymes induced by cephaloridine in the rat kidney cortex. Biochemical pharmacology. 1988 Oct; 37(19):3781-5. doi: 10.1016/0006-2952(88)90416-9. [PMID: 3178892]
  • J H Smith. The use of renal cortical slices from the Fischer 344 rat as an in vitro model to evaluate nephrotoxicity. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1988 Jul; 11(1):132-42. doi: 10.1016/0272-0590(88)90277-1. [PMID: 2905310]
  • T Hayashi, Y Watanabe, K Kumano, R Kitayama, T Yasuda, I Saikawa, J Katahira, T Kumada, K Shimizu. Protective effect of piperacillin against nephrotoxicity of cephaloridine and gentamicin in animals. Antimicrobial agents and chemotherapy. 1988 Jun; 32(6):912-8. doi: 10.1128/aac.32.6.912. [PMID: 3415211]