BROMOBENZENE (BioDeep_00000008454)

   

natural product


代谢物信息卡片


BROMOBENZENE

化学式: C6H5Br (155.9575)
中文名称: 溴苯
谱图信息: 最多检出来源 Macaca mulatta(otcml) 7.28%

分子结构信息

SMILES: Brc1ccccc1
InChI: InChI=1S/C6H5Br/c7-6-4-2-1-3-5-6/h1-5H

描述信息

The simplest member of the class of bromobenzenes, that is benzene in which a single hydrogen has been substituted by a bromine. A liquid at room temperature (m.p. -30degreeC; b.p.760 156degreeC), it is used as a solvent, particularly for large-scale crystallisations, and for the introduction of phenyl groups in organic synthesis.

同义名列表

3 个代谢物同义名

BROMOBENZENE; Bromobenzene; Bromobenzene



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ALB, CASP3, CAT, CYP1A1, CYP2E1, GRHPR, HPGDS, NFE2L2, NQO1, PTGS2
Peripheral membrane protein 4 CYP1A1, CYP2E1, PTGS2, SORD
Endoplasmic reticulum membrane 5 CYP1A1, CYP2E1, HMOX1, HSP90B1, PTGS2
Mitochondrion membrane 1 SORD
Nucleus 7 ALB, CASP3, HMOX1, HSP90B1, NFE2L2, NQO1, PLCZ1
cytosol 14 ALB, CASP3, CAT, GCLM, GPT, GRHPR, GSR, HMOX1, HPGDS, HSP90B1, NFE2L2, NQO1, PLCZ1, SORD
dendrite 1 NQO1
mitochondrial membrane 1 SORD
centrosome 2 ALB, NFE2L2
nucleoplasm 6 CASP3, CD2, HMOX1, HPGDS, NFE2L2, PLCZ1
RNA polymerase II transcription regulator complex 1 NFE2L2
Cell membrane 2 CD2, TNF
Cytoplasmic side 1 HMOX1
Synapse 1 NQO1
cell surface 2 CD2, TNF
glutamatergic synapse 1 CASP3
Golgi apparatus 3 ALB, CD2, NFE2L2
mitochondrial inner membrane 2 CYP1A1, CYP2E1
neuronal cell body 3 CASP3, NQO1, TNF
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 2 NFE2L2, NQO1
plasma membrane 4 ACVR1, CD2, NFE2L2, TNF
Membrane 6 ACVR1, CAT, HMOX1, HSP90B1, NQO1, SORD
caveola 1 PTGS2
extracellular exosome 7 ALB, CAT, GPT, GRHPR, GSR, HSP90B1, SORD
endoplasmic reticulum 4 ALB, HMOX1, HSP90B1, PTGS2
extracellular space 4 ALB, HMOX1, SORD, TNF
perinuclear region of cytoplasm 3 HMOX1, HSP90B1, PLCZ1
mitochondrion 4 CAT, CYP1A1, GRHPR, GSR
protein-containing complex 5 ALB, CAT, CD2, HSP90B1, PTGS2
intracellular membrane-bounded organelle 4 CAT, CYP1A1, CYP2E1, HPGDS
Microsome membrane 3 CYP1A1, CYP2E1, PTGS2
postsynaptic density 1 CASP3
pronucleus 1 PLCZ1
Single-pass type I membrane protein 2 ACVR1, CD2
Secreted 1 ALB
extracellular region 5 ALB, CAT, CD2, HSP90B1, TNF
cytoplasmic side of plasma membrane 1 CD2
mitochondrial outer membrane 1 HMOX1
mitochondrial matrix 2 CAT, GSR
anchoring junction 1 ALB
motile cilium 1 SORD
external side of plasma membrane 3 CD2, GSR, TNF
nucleolus 1 PLCZ1
midbody 1 HSP90B1
apical part of cell 1 ACVR1
cell-cell junction 1 CD2
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cytoplasm, perinuclear region 1 PLCZ1
Mitochondrion inner membrane 2 CYP1A1, CYP2E1
Membrane raft 1 TNF
focal adhesion 2 CAT, HSP90B1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, GRHPR
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 HSP90B1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
ciliary basal body 1 ALB
chromatin 1 NFE2L2
mediator complex 1 NFE2L2
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Cell projection, cilium, flagellum 1 SORD
Melanosome 1 HSP90B1
sperm plasma membrane 1 HSP90B1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 3 ALB, HSP90B1, PTGS2
platelet alpha granule lumen 1 ALB
Single-pass type IV membrane protein 1 HMOX1
Sarcoplasmic reticulum lumen 1 HSP90B1
protein-DNA complex 1 NFE2L2
death-inducing signaling complex 1 CASP3
endocytic vesicle lumen 1 HSP90B1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
sperm head 1 PLCZ1
catalytic complex 1 GRHPR
endoplasmic reticulum chaperone complex 1 HSP90B1
BMP receptor complex 1 ACVR1
activin receptor complex 1 ACVR1
glutamate-cysteine ligase complex 1 GCLM
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Hiroki Yoshioka, Sarah Tominaga, Mai Nishikawa, Yasuro Shinohara, Makoto Nakao, Masae Yoshikawa, Tohru Maeda, Nobuhiko Miura. Different Renal Chronotoxicity of Bromobenzene and Its Intermediate Metabolites in Mice. Biological & pharmaceutical bulletin. 2021; 44(1):150-153. doi: 10.1248/bpb.b20-00694. [PMID: 33390544]
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  • Priya Josson Akkara, Evan Prince Sabina. Pre-treatment with Beta Carotene Gives Protection Against Nephrotoxicity Induced by Bromobenzene via Modulation of Antioxidant System, Pro-inflammatory Cytokines and Pro-apoptotic Factors. Applied biochemistry and biotechnology. 2020 Feb; 190(2):616-633. doi: 10.1007/s12010-019-03111-0. [PMID: 31407161]
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