(-)-Cytisine (BioDeep_00000841815)

   


代谢物信息卡片


(-)-Cytisine

化学式: C11H14N2O (190.1106)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C2CNCC1C3=CC=CC(=O)N3C2
InChI: InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2

描述信息

同义名列表

1 个代谢物同义名

(-)-Cytisine



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 BCL2, PTGS1, PTGS2, S100A12, STAT1
Peripheral membrane protein 3 PTGS1, PTGS2, S100A12
Endoplasmic reticulum membrane 3 BCL2, PTGS1, PTGS2
Nucleus 3 BCL2, S100A12, STAT1
cytosol 4 BCL2, PRKCQ, S100A12, STAT1
dendrite 1 STAT1
nucleoplasm 1 STAT1
RNA polymerase II transcription regulator complex 1 STAT1
Cell membrane 2 GRIK1, S100A12
Multi-pass membrane protein 1 GRIK1
Synapse 1 TAC1
Golgi apparatus 1 PTGS1
neuronal cell body 1 TAC1
presynaptic membrane 1 GRIK1
plasma membrane 3 GRIK1, PRKCQ, S100A12
Membrane 1 BCL2
axon 2 STAT1, TAC1
caveola 1 PTGS2
extracellular exosome 1 PTGS1
endoplasmic reticulum 2 BCL2, PTGS2
extracellular space 1 TAC1
perinuclear region of cytoplasm 1 STAT1
mitochondrion 1 BCL2
protein-containing complex 3 BCL2, PTGS2, STAT1
intracellular membrane-bounded organelle 2 GRIK1, PTGS1
Microsome membrane 2 PTGS1, PTGS2
Secreted 1 S100A12
extracellular region 3 DNAH9, S100A12, TAC1
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
centriolar satellite 1 PRKCQ
motile cilium 1 DNAH9
photoreceptor outer segment 1 PTGS1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
nucleolus 1 STAT1
postsynaptic membrane 1 GRIK1
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 S100A12
microtubule 1 DNAH9
axoneme 1 DNAH9
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Postsynaptic cell membrane 1 GRIK1
kainate selective glutamate receptor complex 1 GRIK1
neuron projection 2 PTGS1, PTGS2
chromatin 1 STAT1
cytoskeleton 1 S100A12
Cytoplasm, cytoskeleton, cilium axoneme 1 DNAH9
Endomembrane system 1 PTGS1
myelin sheath 1 BCL2
secretory granule lumen 1 S100A12
endoplasmic reticulum lumen 1 PTGS2
postsynaptic density membrane 1 GRIK1
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
9+2 motile cilium 1 DNAH9
dynein complex 1 DNAH9
BAD-BCL-2 complex 1 BCL2
ISGF3 complex 1 STAT1
outer dynein arm 1 DNAH9
distal portion of axoneme 1 DNAH9


文献列表

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  • Fangmei Chen, Xiaoying Yin, Yanqing Wang, Yixin Lv, Si Sheng, Sheng Ouyang, Youquan Zhong. Pharmacokinetics, Tissue Distribution, and Druggability Prediction of the Natural Anticancer Active Compound Cytisine N-Isoflavones Combined with Computer Simulation. Biological & pharmaceutical bulletin. 2020 Jun; 43(6):976-984. doi: 10.1248/bpb.b20-00004. [PMID: 32188833]
  • Piotr Tutka, Denis Vinnikov, Ryan J Courtney, Neal L Benowitz. Cytisine for nicotine addiction treatment: a review of pharmacology, therapeutics and an update of clinical trial evidence for smoking cessation. Addiction (Abingdon, England). 2019 11; 114(11):1951-1969. doi: 10.1111/add.14721. [PMID: 31240783]
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  • Yu-hang Wu, Zhong-bao Han, Jia-ze Ma, Yan He, Li-yan Liu, Shi-gang Xin, Zhan Yu. [Intermolecular Interactions between Cytisine and Bovine Serum Albumin A Synchronous Fluorescence Spectroscopic Analysis and Molecular Docking Research]. Guang pu xue yu guang pu fen xi = Guang pu. 2016 Mar; 36(3):765-9. doi: NULL. [PMID: 27400521]
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