Chemical Formula: C11H14N2O
Chemical Formula C11H14N2O
Found 129 metabolite its formula value is C11H14N2O
5-Methoxytryptamine
5-Methoxytryptamine, also known as mexamine or 5-MT, belongs to the class of organic compounds known as tryptamines and derivatives. Tryptamines and derivatives are compounds containing the tryptamine backbone, which is structurally characterized by an indole ring substituted at the 3-position by an ethanamine. It is biosynthesized via the deacetylation of melatonin in the pineal gland. 5-MT acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors. 5-Methoxytryptamine exists in all living organisms, ranging from bacteria to humans. Its affinity for the 5-HT5A receptor is unknown. It has no affinity for the 5-HT3 receptor and is affinity for the 5-HT1E receptor is very weak in comparison to the other 5-HT1 receptors. 5-MT has been shown to occur naturally in the body in low levels. Serotonin derivative proposed as potentiator for hypnotics and sedatives. [HMDB] KEIO_ID M040
Cytisine
N - Nervous system > N07 - Other nervous system drugs > N07B - Drugs used in addictive disorders > N07BA - Drugs used in nicotine dependence C78272 - Agent Affecting Nervous System > C47796 - Cholinergic Agonist > C73579 - Nicotinic Agonist relative retention time with respect to 9-anthracene Carboxylic Acid is 0.054 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.052 Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3]. Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3]. Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3].
N-Methylserotonin
N-methylserotonin is a product of the serotonin-degradative pathway, found in urine specimens of patients with psychiatric disorders (PubMed ID 8747157 ).
2-Methyl-5-hydroxytryptamine
2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects[1].
Alline
Alline is found in onion-family vegetables. Alline is an alkaloid from Chinese chives (Allium odorum) and several other Allium specie
1H-Indol-5-ol, 3-(2-amino-1-methylethyl)-
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists
Indantadol
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent
Cytisinicline
Cytisine is an organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking. It has a role as a nicotinic acetylcholine receptor agonist, a phytotoxin and a plant metabolite. It is an alkaloid, an organic heterotricyclic compound, a secondary amino compound, a lactam and a bridged compound. Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus. Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy. Also known as baptitoxine or sophorine, cytisine has been used as a smoking cessation treatment since 1964, and is relatively unknown in regions outside of central and Eastern Europe. Cytisine is a partial nicotinic acetylcholine agonist with a half-life of 4.8 hours. Recent Phase III clinical trials using Tabex (a brand of Cytisine marketed by Sopharma AD) have shown similar efficacy to varenicline, but at a fraction of the cost. Cytisine is a natural product found in Viscum cruciatum, Thermopsis chinensis, and other organisms with data available. See also: Cytisus scoparius flowering top (part of); Thermopsis lanceolata whole (part of). An organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking. N - Nervous system > N07 - Other nervous system drugs > N07B - Drugs used in addictive disorders > N07BA - Drugs used in nicotine dependence C78272 - Agent Affecting Nervous System > C47796 - Cholinergic Agonist > C73579 - Nicotinic Agonist Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3]. Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3]. Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3].
N-Methylserotonin
A member of the class of tryptamines that is serotonin in which one of the hydrogens attached to the primary amino group is replaced by a methyl group. relative retention time with respect to 9-anthracene Carboxylic Acid is 0.054 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.053
5-Methoxytryptamine
A member of the class of tryptamines that is the methyl ether derivative of serotonin.
Cytisin
N - Nervous system > N07 - Other nervous system drugs > N07B - Drugs used in addictive disorders > N07BA - Drugs used in nicotine dependence C78272 - Agent Affecting Nervous System > C47796 - Cholinergic Agonist > C73579 - Nicotinic Agonist CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2241 Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3]. Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3]. Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3].
1H-Benzimidazole-2-methanol,1-(1-methylethyl)-(9CI)
1H-Benzimidazole-2-methanol,alpha-ethyl-alpha-methyl-,(alphaR)-(9CI)
Pyrrolo[1,2-a]quinoxalin-2-ol,1,2,3,3a,4,5-hexahydro-,(2R,3aR)- (9CI)
Pyrrolo[1,2-a]quinoxalin-2-ol,1,2,3,3a,4,5-hexahydro-,(2S,3aR)- (9CI)
Pyrrolo[1,2-a]pyrazine, 2-acetyl-1-ethylidene-1,2,3,4-tetrahydro- (9CI)
7-amino-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one
1-(7-amino-3,4-dihydroisoquinolin-2(1H)-yl)ethanone
1,2,3,4-TETRAHYDRO-NAPHTHALENE-1-CARBOTHIOIC ACID HYDRAZIDE
5-HYDROXYMETHYL-2-METHYL-4-TRIFLUOROMETHYL-1,3-THIAZOLE
1H-SPIRO[FURO[3,4-C]PYRIDINE-3,4-PIPERIDINE] DIHYDROCHLORIDE
Quinoxaline, 1-acetyl-1,2,3,4-tetrahydro-4-methyl- (9CI)
3-(4,4-DIMETHYL-4,5-DIHYDRO-1,3-OXAZOL-2-YL)-4-METHYLPYRIDINE
6-(TERT-BUTYL) 3-METHYL 2-AMINO-4,7-DIHYDRO-THIENO[2,3-C]PYRIDINE-3,6(5H)-DICARBOXYLATE
1H-Benzimidazole-2-methanol,1-ethyl-alpha-methyl-(9CI)
2-(4,5-DIHYDRO-4,4-DIMETHYLOXAZOL-2-YL)BENZENAMINE
1H-Benzimidazole,5-methoxy-2-(1-methylethyl)-(9CI)
1H-Benzimidazole-2-methanol,alpha-(1-methylethyl)-(9CI)
4,6-DIMETHYL-2-OXO-1-PROPYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE
Pyrrolo[1,2-a]pyrazine-8-carboxaldehyde, 1-ethyl-3,4-dihydro-6-methyl- (9CI)
2-[(4S)-4,5-dihydro-4-(1-Methylethyl)-2-oxazolyl]- yridine
1-(1(R)-ALPHA-METHYLBENZYL)-AZIRIDINE-2(S)-CARBOXAMIDE
Pyrazino[2,1-c][1,4]benzoxazine,1,2,3,4,4a,5-hexahydro-(9Cl)
(5S)-5-amino-3-methyl-2,5-dihydro-1H-3-benzazepin-4-one
1H-Imidazole,4,5-dihydro-4-[(4-methylphenoxy)methyl]-(9CI)
1H-Benzimidazole-2-methanol,alpha,alpha,1-trimethyl-(9CI)
1-(4-FLUORO-PHENYL)-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE
1H-Benzimidazole-2-methanol,alpha,1,5-trimethyl-(9CI)
1-amino-3-Methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
3-(2-aminopropyl)-1H-indol-5-ol
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists
(8bR)-3-methyl-1,2,3a,4-tetrahydropyrrolo[2,3-b]indol-8b-ol
2-Me 5-HT
2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects[1].