Texasin (BioDeep_00000008142)

 

Secondary id: BioDeep_00000270149

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


6,7-Dihydroxy-3-(4-methoxyphenyl)-4-benzopyrone

化学式: C16H12O5 (284.0685)
中文名称: 6,7-二羟基-4-甲氧基异黄酮
谱图信息: 最多检出来源 Homo sapiens(otcml) 16.35%

分子结构信息

SMILES: c1(c(cc2c(c1)occ(c2=O)c1ccc(cc1)OC)O)O
InChI: InChI=1S/C16H12O5/c1-20-10-4-2-9(3-5-10)12-8-21-15-7-14(18)13(17)6-11(15)16(12)19/h2-8,17-18H,1H3

描述信息

同义名列表

4 个代谢物同义名

6,7-Dihydroxy-3-(4-methoxyphenyl)-4-benzopyrone; 6,7-Dihydroxy-4-methoxyisoflavone; Texasin; Texasin



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ABCB1, AIMP2, ALOX15B, ALOX5, ATF4, BCL2, TYR, VEGFA
Peripheral membrane protein 4 ALOX15, ALOX15B, ALOX5, CYP1B1
Endoplasmic reticulum membrane 2 BCL2, CYP1B1
Nucleus 5 AIMP2, ALOX15B, ATF4, BCL2, VEGFA
cytosol 6 AIMP2, ALOX15, ALOX15B, ALOX5, ATF4, BCL2
centrosome 1 ATF4
nucleoplasm 2 ALOX5, ATF4
RNA polymerase II transcription regulator complex 1 ATF4
Cell membrane 4 ABCB1, ALOX15, ALOX15B, ATF4
Multi-pass membrane protein 1 ABCB1
cell surface 2 ABCB1, VEGFA
Golgi apparatus 1 VEGFA
Cytoplasm, cytosol 4 AIMP2, ALOX15, ALOX15B, ALOX5
Lysosome 1 TYR
plasma membrane 3 ABCB1, ALOX15, ALOX15B
Membrane 7 ABCB1, AIMP2, ALOX15, ALOX15B, BCL2, CYP1B1, VEGFA
apical plasma membrane 1 ABCB1
extracellular exosome 2 ABCB1, ALOX15B
endoplasmic reticulum 2 BCL2, VEGFA
extracellular space 2 ALOX5, VEGFA
perinuclear region of cytoplasm 2 ALOX5, TYR
adherens junction 2 ALOX15B, VEGFA
mitochondrion 2 BCL2, CYP1B1
protein-containing complex 2 ATF4, BCL2
intracellular membrane-bounded organelle 2 CYP1B1, TYR
Microsome membrane 1 CYP1B1
Single-pass type I membrane protein 1 TYR
Secreted 1 VEGFA
extracellular region 2 ALOX5, VEGFA
cytoplasmic side of plasma membrane 1 ALOX15
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 ATF4
Nucleus membrane 2 ALOX5, BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 ALOX5, BCL2
Secreted, extracellular space, extracellular matrix 1 VEGFA
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
Apical cell membrane 1 ABCB1
Cytoplasm, perinuclear region 1 ALOX5
pore complex 1 BCL2
Cell junction, focal adhesion 1 ALOX15B
Cytoplasm, cytoskeleton 1 ALOX15B
focal adhesion 1 ALOX15B
Cell junction, adherens junction 1 ALOX15B
extracellular matrix 1 VEGFA
secretory granule 1 VEGFA
nuclear speck 1 ATF4
neuron projection 1 ATF4
chromatin 1 ATF4
cytoskeleton 1 ALOX15B
nuclear envelope 1 ALOX5
Nucleus envelope 1 ALOX5
Lipid droplet 1 ALOX15
Melanosome 1 TYR
Nucleus speckle 1 ATF4
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 1 ALOX5
secretory granule lumen 1 ALOX5
nuclear matrix 1 ALOX5
platelet alpha granule lumen 1 VEGFA
Nucleus matrix 1 ALOX5
nuclear envelope lumen 1 ALOX5
[Isoform a]: Nucleus 1 ALOX15B
external side of apical plasma membrane 1 ABCB1
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
dendrite membrane 1 ATF4
nuclear periphery 1 ATF4
Nucleus intermembrane space 1 ALOX5
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
ATF4-CREB1 transcription factor complex 1 ATF4
ATF1-ATF4 transcription factor complex 1 ATF4
CHOP-ATF4 complex 1 ATF4
Lewy body core 1 ATF4


文献列表

  • Jeong Mi Kim, Ryeo Kyeong Ko, Duk Sang Jung, Sang Suk Kim, Nam Ho Lee. Tyrosinase inhibitory constituents from the stems of Maackia fauriei. Phytotherapy research : PTR. 2010 Jan; 24(1):70-5. doi: 10.1002/ptr.2870. [PMID: 19441007]
  • B Klejdus, J Vacek, L Benesová, J Kopecký, O Lapcík, V Kubán. Rapid-resolution HPLC with spectrometric detection for the determination and identification of isoflavones in soy preparations and plant extracts. Analytical and bioanalytical chemistry. 2007 Dec; 389(7-8):2277-85. doi: 10.1007/s00216-007-1606-3. [PMID: 17899029]