griffonin (BioDeep_00000000080)

PANOMIX_OTCML-2023

代谢物信息卡片

(Z)-2-((4R,5S,6S)-4,5-Dihydroxy-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)cyclohex-2-en-1-ylidene)acetonitrile

化学式: C14H19NO8 (329.1110614)
中文名称: 紫草氰苷
谱图信息: 最多检出来源 Viridiplantae(otcml) 6.77%

分子结构信息

SMILES: C1=CC(=CC#N)C(C(C1O)O)OC2C(C(C(C(O2)CO)O)O)O
InChI: InChI=1S/C14H19NO8/c15-4-3-6-1-2-7(17)9(18)13(6)23-14-12(21)11(20)10(19)8(5-16)22-14/h1-3,7-14,16-21H,5H2/b6-3-/t7-,8-,9+,10-,11+,12-,13+,14+/m1/s1

描述信息

Lithospermoside is a glycoside.
Lithospermoside is a natural product found in Tylosema fassoglense, Semiaquilegia adoxoides, and other organisms with data available.
Lithospermoside (Griffonin) is a nature product isolated from the stem bark of Semiaquilegia adoxoides [1].
Lithospermoside (Griffonin) is a nature product isolated from the stem bark of Semiaquilegia adoxoides [1].

同义名列表

7 个代谢物同义名

(Z)-2-((4R,5S,6S)-4,5-Dihydroxy-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)cyclohex-2-en-1-ylidene)acetonitrile; (2Z)-2-[(4R,5S,6S)-4,5-dihydroxy-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclohex-2-en-1-ylidene]acetonitrile; Acetonitrile,2-[(4R,5S,6S)-6-(b-D-glucopyranosyloxy)-4,5-dihydroxy-2-cyclohexen-1-ylidene]-,(2Z)-; griffonin, (4S-(1Z,4alpha,5alpha,6beta))-isomer; Lithospermoside; Lithosprmoside; griffonin

数据库引用编号

16 个数据库交叉引用编号

ChEBI: CHEBI:81324
KEGG: C17771
PubChem: 101613227
PubChem: 10065132
Metlin: METLIN71891
ChEMBL: CHEMBL1817899
MeSH: griffonin
KNApSAcK: C00030677
chemspider: 8240672
CAS: 63492-69-3
medchemexpress: HY-N0821
PMhub: MS000026073
PubChem: 96024090
NIKKAJI: J435.378A
LOTUS: LTS0135894
wikidata: Q27155262

分类词条

其他

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

390785 - Bauhinia rufa: 10.1371/JOURNAL.PONE.0258016
475907 - Lithospermum officinale: 10.1016/S0031-9422(00)89236-5
549775 - Lophira alata: 10.1016/S0305-1978(02)00187-4
670087 - Lophira lanceolata: 10.1016/S0305-1978(02)00187-4
33090 - Plants: -
349366 - Semiaquilegia adoxoides:
228518 - Tylosema fassoglense: 10.1016/S0305-1978(00)00057-0
33090 - 紫草: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Luiz Leonardo Saldanha, Aislan Quintiliano Delgado, Laurence Marcourt, Nathalia Aparecida de Paula Camaforte, Priscilla Maria Ponce Vareda, Samad Nejad Ebrahimi, Wagner Vilegas, Anne Lígia Dokkedal, Emerson Ferreira Queiroz, Jean-Luc Wolfender, José Roberto Bosqueiro. Hypoglycemic active principles from the leaves of Bauhinia holophylla: Comprehensive phytochemical characterization and in vivo activity profile. PloS one. 2021; 16(9):e0258016. doi: 10.1371/journal.pone.0258016. [PMID: 34559860]
Ofentse Mazimba, Runner R T Majinda, Ceciliah Modibedi, Ishmael B Masesane, Avrelija Cencič, Walter Chingwaru. Tylosema esculentum extractives and their bioactivity. Bioorganic & medicinal chemistry. 2011 Sep; 19(17):5225-30. doi: 10.1016/j.bmc.2011.07.006. [PMID: 21813280]
Q B Han, B Jiang, S X Mei, G Ding, H D Sun, J X Xie, Y Z Liu. Constituents from the roots of Semiaquilegia adoxoides. Fitoterapia. 2001 Jan; 72(1):86-8. doi: 10.1016/s0367-326x(00)00242-2. [PMID: 11163952]