Imipenem (BioDeep_00000007790)
Secondary id: BioDeep_00001868195
human metabolite blood metabolite
代谢物信息卡片
(5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
化学式: C12H17N3O4S (299.09397220000005)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 6.9%
分子结构信息
SMILES: CC(C1C2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O
InChI: InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1
描述信息
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with cilastatin, a renal dipeptidase inhibitor. [PubChem]
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D013845 - Thienamycins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
23 个代谢物同义名
(5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6S)-3-(2-Formimidoylamino-ethylsulphanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid; (5R,6S)-3-(2-Formimidoylamino-ethylsulphanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylate; (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylate; (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate; (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure; Imipenem, N-formimidoyl thienamycin; N-Formimidoyl thienamycin; N Formimidoylthienamycin; N-Formimidoylthienamycin; Anhydrous, imipenem; Imipenem, anhydrous; Anhydrous imipenem; Imipenem anhydrous; SCHEMBL10033978; Imipenemum; Imipemide; Imipenem; zienam; IMP; IPM
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:471744
- KEGG: C06665
- KEGGdrug: D96091
- KEGGdrug: D04515
- PubChem: 104838
- PubChem: 3695
- HMDB: HMDB0015536
- Metlin: METLIN783
- DrugBank: DB01598
- ChEMBL: CHEMBL148
- Wikipedia: Imipenem
- MeSH: Imipenem
- chemspider: 94631
- PMhub: MS000021269
- PubChem: 8890
- CAS: 64221-86-9
- NIKKAJI: J32.525B
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yue Zhang, Di Wu, Qishun Sun, Zhen Luo, Yuhao Zhang, Bowei Wang, Wenting Chen. Atorvastatin combined with imipenem alleviates lung injury in sepsis by inhibiting neutrophil extracellular trap formation via the ERK/NOX2 signaling pathway.
Free radical biology & medicine.
2024 Aug; 220(?):179-191. doi:
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Scientific reports.
2024 01; 14(1):7. doi:
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Microbial pathogenesis.
2023 Dec; 185(?):106397. doi:
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Pathogens and disease.
2022 08; 80(1):. doi:
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Antimicrobial agents and chemotherapy.
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Antimicrobial agents and chemotherapy.
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BMC microbiology.
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Xenobiotica; the fate of foreign compounds in biological systems.
2019 Nov; 49(11):1296-1302. doi:
10.1080/00498254.2018.1558310. [PMID: 30794062] - Pratik Bhagunde, Parul Patel, Mallika Lala, Kenny Watson, William Copalu, Ming Xu, Pooja Kulkarni, Katherine Young, Matthew L Rizk. Population Pharmacokinetic Analysis for Imipenem-Relebactam in Healthy Volunteers and Patients With Bacterial Infections.
CPT: pharmacometrics & systems pharmacology.
2019 10; 8(10):748-758. doi:
10.1002/psp4.12462. [PMID: 31508899] - Daniela Scribano, Valeria Marzano, Stefano Levi Mortera, Meysam Sarshar, Pamela Vernocchi, Carlo Zagaglia, Lorenza Putignani, Anna Teresa Palamara, Cecilia Ambrosi. Insights into the Periplasmic Proteins of Acinetobacter baumannii AB5075 and the Impact of Imipenem Exposure: A Proteomic Approach.
International journal of molecular sciences.
2019 Jul; 20(14):. doi:
10.3390/ijms20143451. [PMID: 31337077] - Le Zou, Fanqi Meng, Lin Hu, Qi Huang, Min Liu, Tao Yin. A novel reversed-phase high-performance liquid chromatographic assay for the simultaneous determination of imipenem and meropenem in human plasma and its application in TDM.
Journal of pharmaceutical and biomedical analysis.
2019 May; 169(?):142-150. doi:
10.1016/j.jpba.2019.01.039. [PMID: 30861406] - Jyoti Verma, Satyabrata Bag, Bipasa Saha, Pawan Kumar, Tarini Shankar Ghosh, Mayanka Dayal, Tarosi Senapati, Seema Mehra, Prasanta Dey, Anbumani Desigamani, Dhirendra Kumar, Preety Rana, Bhoj Kumar, Tushar K Maiti, Naresh C Sharma, Rupak K Bhadra, Ankur Mutreja, G Balakrish Nair, Thandavarayan Ramamurthy, Bhabatosh Das. Genomic plasticity associated with antimicrobial resistance in Vibrio cholerae.
Proceedings of the National Academy of Sciences of the United States of America.
2019 03; 116(13):6226-6231. doi:
10.1073/pnas.1900141116. [PMID: 30867296] - Boutheina Cherif, Hana Triki, Sana Sahnoun, Khaled Hamden, Afifa Sallemi, Slim Charfi, Saloua Lassoued. Imipenem toxicity in male reproductive organs as a result of inflammatory microenvironment and oxidative stress in germinal cells.
Toxicology.
2019 03; 416(?):44-53. doi:
10.1016/j.tox.2019.02.001. [PMID: 30721722] - A Bricheux, L Lenggenhager, S Hughes, A Karmime, P Lescuyer, A Huttner. Therapeutic drug monitoring of imipenem and the incidence of toxicity and failure in hospitalized patients: a retrospective cohort study.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
2019 Mar; 25(3):383.e1-383.e4. doi:
10.1016/j.cmi.2018.11.020. [PMID: 30528370] - Garyfallia Poulakou, Georgios Renieris, Labros Sabrakos, Olympia Zarkotou, Katherine Themeli-Digalaki, Efstathia Perivolioti, Eleni Kraniotaki, Evangelos J Giamarellos-Bourboulis, Nikolaos Zavras. Daptomycin as adjunctive treatment for experimental infection by Acinetobacter baumannii with resistance to colistin.
International journal of antimicrobial agents.
2019 Feb; 53(2):190-194. doi:
10.1016/j.ijantimicag.2018.10.024. [PMID: 30391645] - Sanwang Li, Feifan Xie. Population pharmacokinetics and simulations of imipenem in critically ill patients undergoing continuous renal replacement therapy.
International journal of antimicrobial agents.
2019 Jan; 53(1):98-105. doi:
10.1016/j.ijantimicag.2018.10.006. [PMID: 30626495] - Ying Jiang, Jun Li, Yingrui Zhang, Xinlan Hu, Xiaoguang Zhang, Xiuling Shang, Shurong Gong, Rongguo Yu. Clinical Situations of Bacteriology and Prognosis in Patients with Urosepsis.
BioMed research international.
2019; 2019(?):3080827. doi:
10.1155/2019/3080827. [PMID: 30881985] - Rania Ben Helal, Raoudha Dziri, Meriem Chedly, Naouel Klibi, Farouk Barguellil, Mohamed Selim El Asli, Mohamed Ben Moussa. Occurrence and Characterization of Carbapenemase-Producing Enterobacteriaceae in a Tunisian Hospital.
Microbial drug resistance (Larchmont, N.Y.).
2018 Nov; 24(9):1361-1367. doi:
10.1089/mdr.2018.0013. [PMID: 29596032] - Varsha Rani Gajamer, Amitabha Bhattacharjee, Deepjyoti Paul, Chandrayee Deshamukhya, Ashish Kr Singh, Nilu Pradhan, Hare Krishna Tiwari. Escherichia coli encoding blaNDM-5 associated with community-acquired urinary tract infections with unusual MIC creep-like phenomenon against imipenem.
Journal of global antimicrobial resistance.
2018 09; 14(?):228-232. doi:
10.1016/j.jgar.2018.05.004. [PMID: 29775789] - Antonio Morales, Manuel Campos, Jose M Juarez, Bernardo Canovas-Segura, Francisco Palacios, Roque Marin. A decision support system for antibiotic prescription based on local cumulative antibiograms.
Journal of biomedical informatics.
2018 08; 84(?):114-122. doi:
10.1016/j.jbi.2018.07.003. [PMID: 29981885] - Amit Vikram, John W Schmidt. Functional blaKPC-2 Sequences Are Present in U.S. Beef Cattle Feces Regardless of Antibiotic Use.
Foodborne pathogens and disease.
2018 07; 15(7):444-448. doi:
10.1089/fpd.2017.2406. [PMID: 29672169] - Hao-Yuan Lee, Shih-Yun Hsu, Jen-Fu Hsu, Chyi-Liang Chen, Yi-Hsin Wang, Cheng-Hsun Chiu. Risk factors and molecular epidemiology of Acinetobacter baumannii bacteremia in neonates.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.
2018 Jun; 51(3):367-376. doi:
10.1016/j.jmii.2017.07.013. [PMID: 28830746] - Junting Yang, Shunwen Zhang, Jiangdong Wu, Jie Zhang, Jiangtao Dong, Peng Guo, Suyu Tang, Wanjiang Zhang, Fang Wu. Imipenem and normal saline with cyclophosphamide have positive effects on the intestinal barrier in rats with sepsis.
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia.
2018 Jun; 162(2):90-98. doi:
10.5507/bp.2018.032. [PMID: 29935492] - Saeed Shams, Ali Hashemi, Mohammad Esmkhani, Somaye Kermani, Elham Shams, Alessandra Piccirillo. Imipenem resistance in clinical Escherichia coli from Qom, Iran.
BMC research notes.
2018 May; 11(1):314. doi:
10.1186/s13104-018-3406-6. [PMID: 29776449] - Talles Prosperi de Paula, Patrícia Campi Santos, Raquel Duque do Nascimento Arifa, Angélica T Vieira, Ludmila de Matos Baltazar, Thiago Vinícius Ávila, Caio Tavares Fagundes, Zélia Menezes Garcia, Renata Lacerda Lima, Mauro Martins Teixeira, Danielle G Souza. Treatment with Atorvastatin Provides Additional Benefits to Imipenem in a Model of Gram-Negative Pneumonia Induced by Klebsiella pneumoniae in Mice.
Antimicrobial agents and chemotherapy.
2018 05; 62(5):. doi:
10.1128/aac.00764-17. [PMID: 29463546] - Weihong Shi, Mingyang Duan, Ligang Jie, Weifeng Sun. A successful treatment of severe systemic lupus erythematosus caused by occult pulmonary infection-associated with hemophagocytic syndrome: A case report.
Medicine.
2018 May; 97(19):e0595. doi:
10.1097/md.0000000000010595. [PMID: 29742693] - Hiromu Takemura, Shigemi Terakubo, Ninyo Okamura, Hideki Nakashima. The reduction of l-cystine to l-cysteine in the supernatant of A549 cell culture causes imipenem inactivation.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2018 May; 24(5):341-346. doi:
10.1016/j.jiac.2017.10.020. [PMID: 29496335] - Manal Mohamed Elhassan Taha, Hisham Elraih Homeida, Omer Mohammed Elhassan Dafalla, Siddig Ibrahim Abdelwahab. Multidrug resistance, prevalence and phylogenetic analysis of genes encoding class II and III integrons in clinically isolated Escherichia coli.
Cellular and molecular biology (Noisy-le-Grand, France).
2018 Apr; 64(5):122-126. doi:
10.14715/cmb/2018.64.5.21. [PMID: 29729705] - Matthew L Rizk, Elizabeth G Rhee, Patricia A Jumes, Mark H Gotfried, Tian Zhao, Eric Mangin, Sheng Bi, Cynthia M Chavez-Eng, Zufei Zhang, Joan R Butterton. Intrapulmonary Pharmacokinetics of Relebactam, a Novel β-Lactamase Inhibitor, Dosed in Combination with Imipenem-Cilastatin in Healthy Subjects.
Antimicrobial agents and chemotherapy.
2018 03; 62(3):. doi:
10.1128/aac.01411-17. [PMID: 29311084] - Abeer M Rababa’h, Tamara B Hijjawi, Karem H Alzoubi, Saddam Al Demour, Mera A Ababneh. The Nephroprotective Effect of N-Acetyl-L-Cysteine and Atorvastatin against Imipenem induced Nephrotoxicity.
Current molecular pharmacology.
2018; 11(2):155-161. doi:
10.2174/1874467210666170731115928. [PMID: 28762308] - Alejandro Cabrera Reina, Ana B Martínez-Piernas, Yannis Bertakis, Christina Brebou, Nikolaos P Xekoukoulotakis, Ana Agüera, José Antonio Sánchez Pérez. Photochemical degradation of the carbapenem antibiotics imipenem and meropenem in aqueous solutions under solar radiation.
Water research.
2018 01; 128(?):61-70. doi:
10.1016/j.watres.2017.10.047. [PMID: 29091805] - Takaya Segawa, Tsuyoshi Sekizuka, Satowa Suzuki, Keigo Shibayama, Mari Matsui, Makoto Kuroda. The plasmid-encoded transcription factor ArdK contributes to the repression of the IMP-6 metallo-β-lactamase gene blaIMP-6, leading to a carbapenem-susceptible phenotype in the blaIMP-6-positive Escherichia coli strain A56-1S.
PloS one.
2018; 13(12):e0208976. doi:
10.1371/journal.pone.0208976. [PMID: 30533034] - Roya Ghanavati, Elnaz Ohadi, Hossein Kazemian, Fateme Yazdani, Alireza Torki, Behrooz S Kalani, Gholamreza Irajian. Evaluation of Fosfomycin Activity Against Extended Spectrum Beta Lactamase (ESBL) Producing Enterobacteriaceae Isolated from Three Centers of Tehran, Iran.
Recent patents on anti-infective drug discovery.
2018; 13(2):180-186. doi:
10.2174/1574891x13666180517075803. [PMID: 29769010] - Gabriel Hundeshagen, David N Herndon, Karel D Capek, Ludwik K Branski, Charles D Voigt, Elizabeth A Killion, Janos Cambiaso-Daniel, Michaela Sljivich, Andrew De Crescenzo, Ronald P Mlcak, Michael P Kinsky, Celeste C Finnerty, William B Norbury. Co-administration of vancomycin and piperacillin-tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients.
Critical care (London, England).
2017 12; 21(1):318. doi:
10.1186/s13054-017-1899-3. [PMID: 29262848] - C Melexopoulou, I D Pavlopoulou, A Zormpala, G L Daikos, J N Boletis, S Marinaki. Syndrome of Inappropriate Antidiuretic Hormone Secretion Complicating Systemic Nocardiosis in a Renal Transplant Recipient: A Case Report.
Transplantation proceedings.
2017 Dec; 49(10):2368-2371. doi:
10.1016/j.transproceed.2017.09.015. [PMID: 29198680] - Amal Tahri, Kamilia Ksouda, Rim Kallel, Salima Daoud, Tahia Boudawara, Khaled Mounir Zeghal, Zouheir Sahnoun. A carbapenem antibiotic imipenem/cilastatin induces an oxidative stress-status and gonadotoxic effects in « wistar » rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Nov; 95(?):308-316. doi:
10.1016/j.biopha.2017.08.039. [PMID: 28858728] - Shi-Wei Liu, Xiao-Yang Xu, Jie Xu, Jiu-Yun Yuan, Wei-Kang Wu, Ning Zhang, Ze-Liang Chen. Multi-drug resistant uropathogenic Escherichia coli and its treatment by Chinese medicine.
Chinese journal of integrative medicine.
2017 Oct; 23(10):763-769. doi:
10.1007/s11655-016-2738-0. [PMID: 28028717] - Krishus Nepal, Narayan Dutt Pant, Bibhusan Neupane, Ankit Belbase, Rikesh Baidhya, Ram Krishna Shrestha, Binod Lekhak, Dwij Raj Bhatta, Bharat Jha. Extended spectrum beta-lactamase and metallo beta-lactamase production among Escherichia coli and Klebsiella pneumoniae isolated from different clinical samples in a tertiary care hospital in Kathmandu, Nepal.
Annals of clinical microbiology and antimicrobials.
2017 Sep; 16(1):62. doi:
10.1186/s12941-017-0236-7. [PMID: 28927454] - Imran Ali, Muhammad Shabbir. Antibiotics susceptibility patterns of uropathogenic E. coli with special reference to fluoroquinolones in different age and gender groups.
JPMA. The Journal of the Pakistan Medical Association.
2017 Aug; 67(8):1161-1165. doi:
NULL. [PMID: 28839298] - Anna Silva Machado, Maura S Oliveira, Cristina Sanches, Carlindo Vieira da Silva Junior, David S Gomez, Rolf Gemperli, Silvia Regina Cavani Jorge Santos, Anna S Levin. Clinical Outcome and Antimicrobial Therapeutic Drug Monitoring for the Treatment of Infections in Acute Burn Patients.
Clinical therapeutics.
2017 Aug; 39(8):1649-1657.e3. doi:
10.1016/j.clinthera.2017.06.008. [PMID: 28705450] - So Yeon Kim, Sang Yop Shin, Ji-Young Rhee, Kwan Soo Ko. Imipenem-resistant Gram-negative bacterial isolates carried by persons upon medical examination in Korea.
Journal of microbiology (Seoul, Korea).
2017 Aug; 55(8):612-618. doi:
10.1007/s12275-017-6555-8. [PMID: 28721477] - N Grall, V Lazarevic, N Gaïa, C Couffignal, C Laouénan, E Ilic-Habensus, I Wieder, P Plesiat, C Angebault, M E Bougnoux, L Armand-Lefevre, A Andremont, X Duval, J Schrenzel. Unexpected persistence of extended-spectrum β-lactamase-producing Enterobacteriaceae in the faecal microbiota of hospitalised patients treated with imipenem.
International journal of antimicrobial agents.
2017 Jul; 50(1):81-87. doi:
10.1016/j.ijantimicag.2017.02.018. [PMID: 28499958] - Grazia Piizzi, David T Parker, Yunshan Peng, Markus Dobler, Anup Patnaik, Som Wattanasin, Eugene Liu, Francois Lenoir, Jill Nunez, John Kerrigan, David McKenney, Colin Osborne, Donghui Yu, Leanne Lanieri, Jade Bojkovic, JoAnn Dzink-Fox, Maria-Dawn Lilly, Elizabeth R Sprague, Yipin Lu, Hongming Wang, Srijan Ranjitkar, Lili Xie, Bing Wang, Meir Glick, Lawrence G Hamann, Ruben Tommasi, Xia Yang, Charles R Dean. Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC.
Journal of medicinal chemistry.
2017 06; 60(12):5002-5014. doi:
10.1021/acs.jmedchem.7b00377. [PMID: 28549219] - Gowrishankar Soundararajan, Satya Prathyusha Bhamidimarri, Mathias Winterhalter. Understanding Carbapenem Translocation through OccD3 (OpdP) of Pseudomonas aeruginosa.
ACS chemical biology.
2017 06; 12(6):1656-1664. doi:
10.1021/acschembio.6b01150. [PMID: 28440622] - Rumyana Markovska, Temenuga Stoeva, Lyudmila Boyanova, Petya Stankova, Daniela Pencheva, Radka Kaneva, Vanyo Mitev, Ivan Mitov. Isolation of Escherichia coli ST131 producing KPC-2 in Bulgaria.
Infectious diseases (London, England).
2017 May; 49(5):429-431. doi:
10.1080/23744235.2016.1270464. [PMID: 28049378] - Marina Oviaño, Cecilia de la Luna Ramírez, Luis Pedro Barbeyto, Germán Bou. Rapid direct detection of carbapenemase-producing Enterobacteriaceae in clinical urine samples by MALDI-TOF MS analysis.
The Journal of antimicrobial chemotherapy.
2017 05; 72(5):1350-1354. doi:
10.1093/jac/dkw579. [PMID: 28119478] - Z Zhu, G W Cao, J J Bao, Z H Hu, Z Shen, H Tao, B Cao, F Xu. [Effects of application of vancomycin in the early stage of patients with extremely severe burn].
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns.
2017 Apr; 33(4):206-210. doi:
10.3760/cma.j.issn.1009-2587.2017.04.004. [PMID: 28427133] - Marcelo V Radisic, Laura Linares, Javier Afeltra, Natalia Pujato, Roxana G Vitale, Martin Bravo, Ana C Dotta, Domingo H Casadei. Acute pulmonary involvement by paracoccidiodomycosis disease immediately after kidney transplantation: Case report and literature review.
Transplant infectious disease : an official journal of the Transplantation Society.
2017 Apr; 19(2):. doi:
10.1111/tid.12655. [PMID: 28039947] - Hana Suchánková, Michal Lipš, Karel Urbánek, Michael N Neely, Jan Strojil. Is continuous infusion of imipenem always the best choice?.
International journal of antimicrobial agents.
2017 Mar; 49(3):348-354. doi:
10.1016/j.ijantimicag.2016.12.005. [PMID: 28189734] - Esther Ríos, María Carmen López, Iciar Rodríguez-Avial, Esther Culebras, Juan José Picazo. Detection of Escherichia coli ST131 clonal complex (ST705) and Klebsiella pneumoniae ST15 among faecal carriage of extended-spectrum β-lactamase- and carbapenemase-producing Enterobacteriaceae.
Journal of medical microbiology.
2017 Feb; 66(2):169-174. doi:
10.1099/jmm.0.000399. [PMID: 27902381] - James A Karlowsky, Daryl J Hoban, Meredith A Hackel, Sibylle H Lob, Daniel F Sahm. Antimicrobial susceptibility of Gram-negative ESKAPE pathogens isolated from hospitalized patients with intra-abdominal and urinary tract infections in Asia-Pacific countries: SMART 2013-2015.
Journal of medical microbiology.
2017 Jan; 66(1):61-69. doi:
10.1099/jmm.0.000421. [PMID: 28051952] - Fabrice Compain, Benjamin Rossi, Clémence Richaud, Emmanuel Guerot, Hidayeth Rostane, Sophie Jarraud, Isabelle Podglajen. Photo Quiz: A 44-Year-Old Kidney Transplant Patient with Pneumonia.
Journal of clinical microbiology.
2017 01; 55(1):1-2. doi:
10.1128/jcm.masthead.55-1. [PMID: 28031443] - Mario Martínez-Florensa, Marta Consuegra-Fernández, Fernando Aranda, Noelia Armiger-Borràs, Marianna Di Scala, Esther Carrasco, Jerónimo Pachón, Jordi Vila, Gloria González-Aseguinolaza, Francisco Lozano. Protective Effects of Human and Mouse Soluble Scavenger-Like CD6 Lymphocyte Receptor in a Lethal Model of Polymicrobial Sepsis.
Antimicrobial agents and chemotherapy.
2017 01; 61(1):. doi:
10.1128/aac.01391-16. [PMID: 27895015] - Bradley A Boucher, Joanna Q Hudson, David M Hill, Joseph M Swanson, G Christopher Wood, S Casey Laizure, Angela Arnold-Ross, Zhe-Yi Hu, William L Hickerson. Pharmacokinetics of Imipenem/Cilastatin Burn Intensive Care Unit Patients Undergoing High-Dose Continuous Venovenous Hemofiltration.
Pharmacotherapy.
2016 12; 36(12):1229-1237. doi:
10.1002/phar.1866. [PMID: 27862103] - Aryann R Ganjo, Delshad M Maghdid, Isam Y Mansoor, Dik J Kok, Juliette A Severin, Henri A Verbrugh, Deborah Kreft, M H Fatah, A A Alnakshabandi, Asad Dlnya, Anette M Hammerum, Kim Ng, Wil Goessens. OXA-Carbapenemases Present in Clinical Acinetobacter baumannii-calcoaceticus Complex Isolates from Patients in Kurdistan Region, Iraq.
Microbial drug resistance (Larchmont, N.Y.).
2016 Dec; 22(8):627-637. doi:
10.1089/mdr.2015.0060. [PMID: 27003287] - Chien-Chih Wu, Tsung-Yu Pai, Fei-Yuan Hsiao, Li-Jiuan Shen, Fe-Lin Lin Wu. The Effect of Different Carbapenem Antibiotics (Ertapenem, Imipenem/Cilastatin, and Meropenem) on Serum Valproic Acid Concentrations.
Therapeutic drug monitoring.
2016 10; 38(5):587-92. doi:
10.1097/ftd.0000000000000316. [PMID: 27322166] - L Y Deng, Z C Yang, Y L Gong, G T Huang, S P Yin, B Jiang, Y Z Peng. [Therapeutic effect of phages on extensively drug-resistant Acinetobacter baumannii-induced sepsis in mice].
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns.
2016 Sep; 32(9):523-8. doi:
10.3760/cma.j.issn.1009-2587.2016.09.003. [PMID: 27647067]