(R)-Pronuciferine (BioDeep_00000007494)
Secondary id: BioDeep_00001869235
human metabolite Endogenous
代谢物信息卡片
化学式: C19H21NO3 (311.15213560000007)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: c1(c2c3c(cc1OC)CCN([C@@H]3C[C@@]12C=CC(=O)C=C1)C)OC
InChI: InChI=1S/C19H21NO3/c1-20-9-6-12-10-15(22-2)18(23-3)17-16(12)14(20)11-19(17)7-4-13(21)5-8-19/h4-5,7-8,10,14H,6,9,11H2,1-3H3
描述信息
Alkaloid from Nelumbo nucifera (East India lotus). (R)-Pronuciferine is found in many foods, some of which are poppy, coffee and coffee products, sacred lotus, and cherimoya.
(R)-Pronuciferine is found in cherimoya. (R)-Pronuciferine is an alkaloid from Nelumbo nucifera (East India lotus
同义名列表
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:42
- KEGG: C09611
- PubChem: 200480
- PubChem: 628376
- HMDB: HMDB0030344
- Metlin: METLIN67847
- ChEMBL: CHEMBL237766
- KNApSAcK: C00001905
- foodb: FDB002188
- chemspider: 545754
- CAS: 17236-29-2
- CAS: 2128-60-1
- PMhub: MS000020872
- PubChem: 11802
- 3DMET: B03127
- NIKKAJI: J20.736E
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
41 个相关的物种来源信息
- 13440 Cocculus: 10.1016/0040-4020(80)88040-9
- 1433320 Berberis montana:
- 174969 Uvaria: 10.1016/S0305-1978(97)00101-4
- 1433329 Berberis sibirica:
- 49314 Annona cherimola: 10.1002/JCCS.199900010
- 248829 Meconopsis cambrica: 10.1021/NP50013A012
- 4432 Nelumbo nucifera:
- 379217 Cissampelos capensis: 10.3390/MOLECULES16043001
- 341009 Antizoma angustifolia: 10.1016/J.BSE.2004.04.003
- 63812 Peumus boldus: 10.1021/NP50033A021
- 152359 Cocculus laurifolius: 10.1016/0040-4020(80)88040-9
- 1433329 Berberis sibirica:
- 174962 Uvaria dulcis: 10.1016/S0305-1978(97)00101-4
- 461634 Stephania rotunda: 10.1021/NP50022A007
- 63805 Glossocalyx longicuspis: 10.1021/NP50041A025
- 1317845 Glossocalyx brevipes: 10.1021/NP50041A025
- 2516453 Stephania corymbosa: 10.1248/YAKUSHI1947.89.12_1691
- 63807 Gyrocarpus americanus: 10.1016/0031-9422(88)83172-8
- 1433320 Berberis montana: 10.1021/NP9000976
- 152353 Hypserpa nitida: 10.1016/J.BMCL.2007.08.027
- 13440 Cocculus: 10.1016/0040-4020(80)88040-9
- 1433320 Berberis montana:
- 174969 Uvaria: 10.1016/S0305-1978(97)00101-4
- 1433329 Berberis sibirica:
- 49314 Annona cherimola: 10.1002/JCCS.199900010
- 248829 Meconopsis cambrica: 10.1021/NP50013A012
- 4432 Nelumbo nucifera:
- 379217 Cissampelos capensis: 10.3390/MOLECULES16043001
- 341009 Antizoma angustifolia: 10.1016/J.BSE.2004.04.003
- 63812 Peumus boldus: 10.1021/NP50033A021
- 152359 Cocculus laurifolius: 10.1016/0040-4020(80)88040-9
- 1433329 Berberis sibirica:
- 174962 Uvaria dulcis: 10.1016/S0305-1978(97)00101-4
- 461634 Stephania rotunda: 10.1021/NP50022A007
- 63805 Glossocalyx longicuspis: 10.1021/NP50041A025
- 1317845 Glossocalyx brevipes: 10.1021/NP50041A025
- 2516453 Stephania corymbosa: 10.1248/YAKUSHI1947.89.12_1691
- 63807 Gyrocarpus americanus: 10.1016/0031-9422(88)83172-8
- 1433320 Berberis montana: 10.1021/NP9000976
- 152353 Hypserpa nitida: 10.1016/J.BMCL.2007.08.027
- 9606 Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Michael E Pyne, Nicholas D Gold, Vincent J J Martin. Pathway elucidation and microbial synthesis of proaporphine and bis-benzylisoquinoline alkaloids from sacred lotus (Nelumbo nucifera).
Metabolic engineering.
2023 Mar; ?(?):. doi:
10.1016/j.ymben.2023.03.010. [PMID: 37004909] - Mamiko Yano, Souichi Nakashima, Yoshimi Oda, Seikou Nakamura, Hisashi Matsuda. BBB-permeable aporphine-type alkaloids in Nelumbo nucifera flowers with accelerative effects on neurite outgrowth in PC-12 cells.
Journal of natural medicines.
2020 Jan; 74(1):212-218. doi:
10.1007/s11418-019-01368-7. [PMID: 31707550] - Omer Bayazeid, Cemil Can Eylem, Tuba Reçber, Funda Nuray Yalçın, Sedef Kır, Emirhan Nemutlu. An LC-ESI-MS/MS method for the simultaneous determination of pronuciferine and roemerine in some Papaver species.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2018 Oct; 1096(?):223-227. doi:
10.1016/j.jchromb.2018.08.020. [PMID: 30189375] - Chengjun Ma, Gang Li, Yanfeng He, Bo Xu, Xiangquan Mi, Honglun Wang, Zhenhua Wang. Pronuciferine and nuciferine inhibit lipogenesis in 3T3-L1 adipocytes by activating the AMPK signaling pathway.
Life sciences.
2015 Sep; 136(?):120-5. doi:
10.1016/j.lfs.2015.07.001. [PMID: 26164185] - Jong Hoon Ahn, Eun Sil Kim, Chul Lee, Soonok Kim, Soo-Hyun Cho, Bang Yeon Hwang, Mi Kyeong Lee. Chemical constituents from Nelumbo nucifera leaves and their anti-obesity effects.
Bioorganic & medicinal chemistry letters.
2013 Jun; 23(12):3604-8. doi:
10.1016/j.bmcl.2013.04.013. [PMID: 23642481] - Seikou Nakamura, Souichi Nakashima, Genzo Tanabe, Yoshimi Oda, Nami Yokota, Katsuyoshi Fujimoto, Takahiro Matsumoto, Rika Sakuma, Tomoe Ohta, Keiko Ogawa, Shino Nishida, Hisako Miki, Hisashi Matsuda, Osamu Muraoka, Masayuki Yoshikawa. Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells.
Bioorganic & medicinal chemistry.
2013 Feb; 21(3):779-87. doi:
10.1016/j.bmc.2012.11.038. [PMID: 23270663] - Pi Cheng, Yun-bao Ma, Shu-ying Yao, Quan Zhang, En-jun Wang, Meng-hong Yan, Xue-mei Zhang, Feng-xue Zhang, Ji-jun Chen. Two new alkaloids and active anti-hepatitis B virus constituents from Hypserpa nitida.
Bioorganic & medicinal chemistry letters.
2007 Oct; 17(19):5316-20. doi:
10.1016/j.bmcl.2007.08.027. [PMID: 17723297]