Zaluzanin C (BioDeep_00000007489)
PANOMIX_OTCML-2023 natural product
代谢物信息卡片
化学式: C15H18O3 (246.1256)
中文名称:
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 95.12%
分子结构信息
SMILES: C=C1C(=O)OC2C1CCC(=C)C1CC(O)C(=C)C12
InChI: InChI=1S/C15H18O3/c1-7-4-5-10-8(2)15(17)18-14(10)13-9(3)12(16)6-11(7)13/h10-14,16H,1-6H2/t10-,11-,12-,13-,14-/m0/s1
描述信息
A sesquiterpene lactone that is decahydroazuleno[4,5-b]furan-2(3H)-one substituted by methylidene groups at positions 3, 6 and 9 and a hydroxy group at position 8.
同义名列表
3 个代谢物同义名
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:10103
- KEGG: C09606
- PubChem: 72646
- PubChem: 425954
- Metlin: METLIN67843
- ChEMBL: CHEMBL462318
- KNApSAcK: C00003397
- CAS: 16838-87-2
- PMhub: MS000020867
- MetaboLights: MTBLC10103
- PubChem: 11797
- 3DMET: B03123
- NIKKAJI: J14.016C
- KNApSAcK: 10103
- LOTUS: LTS0168502
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
59 个相关的物种来源信息
- 41469 - Ainsliaea: LTS0168502
- 41470 - Ainsliaea acerifolia: 10.1007/S10600-013-0546-8
- 41470 - Ainsliaea acerifolia: LTS0168502
- 418257 - Ainsliaea fragrans: 10.1016/0031-9422(82)83061-6
- 418257 - Ainsliaea fragrans: LTS0168502
- 41477 - Arctotis: LTS0168502
- 563877 - Arctotis revoluta: 10.1016/0031-9422(90)89036-9
- 563877 - Arctotis revoluta: LTS0168502
- 4210 - Asteraceae: LTS0168502
- 130238 - Brachylaena: LTS0168502
- 130239 - Brachylaena discolor: LTS0168502
- 3020428 - Brachylaena discolor var. transvaalensis: LTS0168502
- 41503 - Centaurea: 10.1016/S0031-9422(00)89537-0
- 41503 - Centaurea: LTS0168502
- 130240 - Chaetanthera: LTS0168502
- 368868 - Chaetanthera chilensis: LTS0168502
- 368870 - Chaetanthera chilensis var. tenuifolia: 10.1016/S0031-9422(96)00517-1
- 368870 - Chaetanthera chilensis var. tenuifolia: LTS0168502
- 41544 - Cheirolophus: 10.1016/S0031-9422(00)89537-0
- 41544 - Cheirolophus: LTS0168502
- 65000 - Cheirolophus sempervirens: 10.1016/S0031-9422(00)89537-0
- 65000 - Cheirolophus sempervirens: LTS0168502
- 4264 - Cynara: LTS0168502
- 157702 - Cynara cornigera: 10.1016/S0031-9422(00)80561-0
- 157702 - Cynara cornigera: LTS0168502
- 935151 - Cynara sibthorpiana: 10.1016/S0031-9422(00)80561-0
- 935151 - Cynara sibthorpiana: LTS0168502
- 2759 - Eukaryota: LTS0168502
- 41583 - Gochnatia: LTS0168502
- 1542350 - Gochnatia vernonioides: 10.1016/S0031-9422(00)84955-9
- 1542350 - Gochnatia vernonioides: LTS0168502
- 496630 - Hyalis argentea:
- 3433 - Lauraceae: LTS0168502
- 85222 - Laurus: LTS0168502
- 85223 - Laurus nobilis: 10.1016/S0024-3205(00)00542-7
- 85223 - Laurus nobilis: LTS0168502
- 3398 - Magnoliopsida: LTS0168502
- 92914 - Onopordum: LTS0168502
- 41629 - Saussurea: 10.1016/0031-9422(83)80031-4
- 41629 - Saussurea: LTS0168502
- 324593 - Saussurea costus: 10.1021/NP030147E
- 324593 - Saussurea costus: LTS0168502
- 324593 - Saussurea costus: NA
- 200489 - Saussurea involucrata: LTS0168502
- 200489 - Saussurea involucrata: NA
- 481597 - Scalesia: 10.1016/S0031-9422(97)00464-0
- 481597 - Scalesia: LTS0168502
- 35493 - Streptophyta: LTS0168502
- 261619 - Takhtajaniantha austriaca: 10.1021/NP900378C
- 58023 - Tracheophyta: LTS0168502
- 122556 - Urospermum: LTS0168502
- 122557 - Urospermum dalechampii: 10.1016/S0031-9422(00)89805-2
- 122557 - Urospermum dalechampii: LTS0168502
- 33090 - Viridiplantae: LTS0168502
- 89038 - Youngia: LTS0168502
- 89039 - Youngia japonica: 10.1055/S-2005-916182
- 89039 - Youngia japonica: LTS0168502
- 183101 - Zaluzania: 10.1016/S0040-4020(01)83283-X
- 183101 - Zaluzania: LTS0168502
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Ji-Won Jung, Feng Wang, Ayman Turk, Jeong-Su Park, Hwan Ma, Yuanqiang Ma, Hye-Rin Noh, Guoyan Sui, Dong-Su Shin, Mi-Kyeong Lee, Yoon Seok Roh. Zaluzanin C Alleviates Inflammation and Lipid Accumulation in Kupffer Cells and Hepatocytes by Regulating Mitochondrial ROS.
Molecules (Basel, Switzerland).
2023 Nov; 28(22):. doi:
10.3390/molecules28227484
. [PMID: 38005205] - Navneet Kishore, Pradeep Kumar, Karuna Shanker, Akhilesh Kumar Verma. Human disorders associated with inflammation and the evolving role of natural products to overcome.
European journal of medicinal chemistry.
2019 Oct; 179(?):272-309. doi:
10.1016/j.ejmech.2019.06.034
. [PMID: 31255927] - Sang Zin Choi, Min Cheol Yang, Sang Un Choi, Kang Ro Lee. Cytotoxic terpenes and lignans from the roots of Ainsliaea acerifolia.
Archives of pharmacal research.
2006 Mar; 29(3):203-8. doi:
10.1007/bf02969394
. [PMID: 16596992] - Chang-Ming Sun, Wan-Jr Syu, Ming-Jaw Don, Jang-Jih Lu, Gum-Hee Lee. Cytotoxic sesquiterpene lactones from the root of Saussurea lappa.
Journal of natural products.
2003 Sep; 66(9):1175-80. doi:
10.1021/np030147e
. [PMID: 14510592] - C L Cantrell, S G Franzblau, N H Fischer. Antimycobacterial plant terpenoids.
Planta medica.
2001 Nov; 67(8):685-94. doi:
10.1055/s-2001-18365
. [PMID: 11731906] - J M Megaw, L D Johnson. Glycoprotein synthesized by cultured cells: effects of serum concentrations and buffers on sugar content.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1979 May; 161(1):60-5. doi:
10.3181/00379727-161-40490
. [PMID: 441071]